What klonopin used for


Clonazepam (Klonopin) | NAMI: National Alliance on Mental Illness

Brand name: Klonopin®

  • Tablet: 0.5 mg, 1 mg, 2 mg
  • Wafer (orally disintegrating tablet): 0.125 mg, 0.25 mg, 0.5 mg, 1 mg, 2 mg

Generic name: clonazepam (kloe NA ze pam)

All FDA black box warnings are at the end of this fact sheet. Please review before taking this medication.

What Is Clonazepam And What Does It Treat?

Clonazepam is a benzodiazepine. It is approved for the treatment of panic disorder (with or without agoraphobia), as well as certain types of seizure disorders. However, benzodiazepines are also commonly used to treat difficulty sleeping and alcohol withdrawal.

Panic Disorder occurs when a person experiences unexpected and repeated episodes of intense fear. These episodes have physical symptoms including chest pain, shortness of breath, heart palpitations, sweating, dizziness, and nausea. Fear of future episodes is also part of panic disorder.

What Is The Most Important Information I Should Know About Clonazepam?

Do not drive a car or operate machinery until you know how this medication affects you because you may notice that you feel tired or dizzy.

When starting clonazepam, anxiety or insomnia may improve rapidly or over a period of days.

Benzodiazepines, such as clonazepam, are often used for short periods of time only. They may produce emotional and/or physical dependence (addiction) even when used as recommended. With input from you, your health care provider will assess how long you will need to take the medicine.

Do not stop taking clonazepam without talking to your healthcare provider first. Stopping clonazepam abruptly may result in one or more of the following withdrawal symptoms: irritability, nausea, tremor, dizziness, blood pressure changes, rapid heart rate, and seizures. Withdrawal reactions may occur when dosage reduction occurs for any reason.

The use of clonazepam with drugs like opioid medications has led to serious side effects including slowed and difficulty breathing and death. Opioid drugs are medications used to treat pain and include medications such as: codeine, oxycodone, morphine, and illegal drugs like heroin. Some opioid medications are also in cough syrup.

If you are taking clonazepam with an opioid medication, get medical assistance immediately if you feel dizziness or sleepiness, if you have slow or troubled breathing, or if you pass out. Caregivers must get medical help right away if a patient does not respond and does not wake up.

Avoid alcohol while taking this medication.

Are There Specific Concerns About Clonazepam And Pregnancy?

If you are planning on becoming pregnant, notify your healthcare provider to best manage your medications. People living with anxiety disorders who wish to become pregnant face important decisions regarding risk versus benefit of benzodiazepine use in pregnancy. Clonazepam can increase the risk of premature birth and low birth weight. Newborn withdrawal and “floppy baby syndrome” are other possible side effects. It is important to discuss this with your doctor and caregivers.

Regarding breastfeeding, caution is advised since clonazepam does pass into breast milk.

What Should I Discuss With My Healthcare Provider Before Taking Clonazepam?

  • Symptoms of your condition that bother you the most
  • If you have thoughts of suicide or harming yourself
  • Medications you have taken in the past for your condition, whether they were effective or caused any adverse effects
  • If you experience side effects from your medications, discuss them with your health care provider. Some side effects may pass with time, but others may require changes in the medication.
  • Any other psychiatric or medical problems you have including obstructive sleep apnea
  • All other medications you are currently taking (including over the counter products and herbal and nutritional supplements) and any medication allergies you have
  • Other non-medication treatment you are receiving such as talk therapy or substance abuse treatment. Your provider can explain how these different treatments work with the medication
  • If you are elderly or are prone to falls
  • If you are pregnant, plan to become pregnant, or are breast-feeding
  • If you have acute narrow-angle glaucoma or untreated open-angle glaucoma
  • If you have liver disease
  • If you have phenylketonuria (PKU)
  • If you drink alcohol or use drugs

How Should I Take Clonazepam?

Clonazepam may be taken with or without food. Take with food if you experience an upset stomach.

Clonazepam may be taken every day at regular times or on an as needed (“PRN”) basis. Typically, your healthcare provider will limit the number of doses you should take in one day.

Your health care provider will determine the dose and method of taking the medication that is right for you based upon your response.

Clonazepam oral disintegrating tablets must remain in their original packaging. Open the package with clean dry hands before each dose. Do not try to put tablets in a pillbox if you take the orally disintegrating tablets. Take the tablets right away, do not store for later use.

Clonazepam oral disintegrating tablets will dissolve in your mouth within seconds and can be swallowed with or without liquid.

If you take the medication every day (instead of ‘as needed’), use a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take it. You may also ask a family member or a friend to remind you or check in with you to be sure you are taking your medication.

What Happens If I Miss A Dose Of Clonazepam?

If you miss a dose of clonazepam, take it as soon as you remember, unless it is closer to the time of your next dose. Discuss this with your healthcare provider. Do not double your next dose or take more than what is prescribed.

What Should I Avoid While Taking Clonazepam?

Avoid drinking alcohol and using illegal drugs while you are taking clonazepam. They may decrease the benefits (e. g., worsen your condition) and increase the adverse effects (e.g., sedation) of the medication. Alcohol increases the risk of accidental overdose with medications like clonazepam.

What Happens If I Overdose With Clonazepam?

If an overdose occurs call your doctor or 911. You may need urgent medical care. You may also contact the poison control center at 1-800-222-1222.

Symptoms of overdose include confusion, impaired coordination, slow reflexes, coma, and death.

A specific treatment to reverse the effects of clonazepam does exist. This medicine, called flumazenil, can reverse the effects of clonazepam but must be given through an IV at a hospital. Only a doctor can decide if you need this medication.

What Are Possible Side Effects Of Clonazepam?

Common side effects

  • Feeling dizzy, drowsy, fatigued, or lightheaded
  • Impaired coordination, decreased ability to concentrate

If you experience these side effects after starting clonazepam they will often improve over the first week or two as you continue to take the medication.

Rare/serious side effects

  • Shortness of breath, trouble speaking, feeling very tired, dizziness, or passing out.
  • Increased heart rate, headache, memory impairment, irritability, and restlessness may occur.
  • Some people taking benzodiazepines develop a severe allergic reaction and swelling of the face. This can occur as early as with the first dose.
  • Some people taking benzodiazepines for sleep have experienced various behaviors while they were asleep/not fully awake, such as sleep driving, making phone calls, and preparing or eating food. The individuals have no memory of the events when they awaken.
  • Signs of feeling depressed or low mood, thoughts of harming or killing yourself, or lack of interest in life.

Are There Any Risks For Taking Clonazepam For Long Periods Of Time?

Clonazepam is a safe and effective medication when used as directed. Benzodiazepines may produce emotional and/or physical dependence (addiction) even when used as recommended. Physical dependence may develop after 2 or more weeks of daily use. The risk of withdrawal reactions when stopping therapy with clonazepam is increased with prolonged use of the medication. 

What Other Medications May Interact With Clonazepam?

The following medications may increase the levels and effects of clonazepam:

  • Ketoconazole (Nizoral®), itraconazole (Sporanox®), nefazodone (Serzone®), fluvoxamine (Luvox®), cimetidine (Tagamet®), and ritonavir (Norvir®)

The following medications may decrease the levels and effects of clonazepam:

  • Carbamazepine (Tegretol®), phenytoin (Dilantin®), and phenobarbital (Luminal®)

Clonazepam should not be taken with other benzodiazepine medications.

Clonazepam may cause drowsiness, so caution should be used when combining it with other medications that cause drowsiness. These could include:

  • Antihistamines such as diphenhydramine (Benadryl®)
  • Narcotic pain medication such as morphine, oxycodone (OxyContin®), and hydrocodone (Vicodin® and Lortab®)
  • Opioid cough medications such as codeine cough syrup
  • Sleeping medications such as zolpidem (Ambien®)
  • Other anti-anxiety medications, antipsychotic medications, certain anticonvulsant medications, and tricyclic antidepressant medications (such as amitriptyline)

How Long Does It Take For Clonazepam To Work?

When starting clonazepam, anxiety or insomnia may improve rapidly or over a period of days or within hours of the first dose of medication.

Summary of FDA Black Box Warnings

The FDA has found that benzodiazepine drugs, such as clonazepam, when used in combination with opioid medications or other sedating medications can result in serious adverse reactions including slowed or difficult breathing and death. Patients taking opioids with benzodiazepines, other sedating medications, or alcohol, and caregivers of these patients, should seek immediate medical attention if that start to experience unusual dizziness or lightheadedness, extreme sleepiness, slow or difficulty breathing, or unresponsiveness.

As a benzodiazepine, clonazepam comes with the risk of abuse, misuse, and addiction to the medication. Physical dependence to clonazepam can occur with prolonged use of the medication. A withdrawal reaction may occur when stopping clonazepam, but this risk can be reduced by slowly reducing the dose of clonazepam when stopping. Do not stop taking clonazepam abruptly, and do not make any changes to therapy without consulting your health care provider.

Provided by

(September 2021)

©2021 The College of Psychiatric and Neurologic Pharmacists (CPNP) and the National Alliance on Mental Illness (NAMI). CPNP and NAMI make this document available under the Creative Commons Attribution-No Derivatives 4.0 International License. Last Updated: January 2016.

This information is being provided as a community outreach effort of the College of Psychiatric and Neurologic Pharmacists. This information is for educational and informational purposes only and is not medical advice. This information contains a summary of important points and is not an exhaustive review of information about the medication. Always seek the advice of a physician or other qualified medical professional with any questions you may have regarding medications or medical conditions. Never delay seeking professional medical advice or disregard medical professional advice as a result of any information provided herein. The College of Psychiatric and Neurologic Pharmacists disclaims any and all liability alleged as a result of the information provided herein.

Facts, Side Effects, Cost, Dosing

What is Klonopin?

Klonopin is a medication that belongs to a class known as benzodiazepines. The medication is used to treat seizures, panic attacks, and anxiety. Sometimes the medication is used as a secondary medication to manage symptoms of mania in people with bipolar disorder.

When did the U.S. Food and Drug Administration (FDA) approve the medication?

Clonazepam, the generic version of Klonopin, was first approved by the FDA in 1998.

Is there a generic version of Klonopin?

Yes, the generic version is known as clonazepam and is sold in the U.S.

Are there any major differences between Klonopin and other medications used to treat bipolar disorder?

Anti-anxiety drugs like Klonopin are sometimes prescribed to manage severe manic symptoms associated with bipolar disorder, but Klonopin is not a primary medication used to treat bipolar disorder. Klonopin is often prescribed in combination with other medications to manage symptoms. Benzodiazepines like Klonopin can be habit-forming, so persons with bipolar disorder who have a history of substance dependence may do better with other medications. The drug comes in tablet and orally disintegrating form.

Can children take Klonopin?

Children can be prescribed Klonopin to treat seizure disorder, but the drug’s safety and effectiveness have not been studied for those with panic disorder or bipolar disorder. Talk to your child’s doctor about the risks of the medication.

Are there potential interaction issues for people taking Klonopin and any other drugs?

There are hundreds of drugs which are known to interact with Klonopin in major, moderate, or mild ways, so let your doctor know what other medications you are taking before you begin taking the medication, including over the counter medications, herbals, and supplements. Taking some medications with Klonopin increases the risk of breathing problems or coma, so talk to your doctor if you take codeine, hydrocodone, hydromorphone, fentanyl, meperidine, methadone, morphine, oxycodone, and tramadol. If you take these medications and experience dizziness, sleepiness, lightheadedness, difficulty breathing, or unresponsiveness, seek emergency medical care immediately. It is not recommended to take Klonopin with alcohol as Klonopin may enhance the effects of alcohol.

Are there any other medical conditions that would make someone ineligible for Klonopin therapy?

Talk to your doctor about other medical conditions before you take Klonopin, such as glaucoma and liver disease. Also tell your doctor if you have a history of substance use problems or suicidal thoughts.

What is the typical dose that would be prescribed to someone taking Klonopin?

Dosage will vary depending on the age of the patient and the condition being treated.

What do I do if I miss a dose?

Take the dose of Klonopin when you remember, but skip the missed dose if it’s almost time for your next dose. You should never take extra doses of the medication to make up for missed doses.

What side effects can Klonopin cause?

Common side effects may vary depending on the diagnosis, and can include:

It is recommended that you wait to drive or operate machinery until you know how the medication affects you. It is also recommended that people avoid alcohol and illegal drugs while on the medication, as they can worsen adverse effects. Moreover, taking the medication at bedtime may be preferred because of its tendency to cause drowsiness. Report side effects to your doctor immediately. Serious side effects can include rash, hives, hoarseness, trouble breathing, swelling, or difficulty breathing or swallowing. You can also report side effects to the FDA at 1-800-FDA-1088 or online.

What are the potential psychological side effects of taking Klonopin?

Klonopin may cause suicidal thoughts and behaviors in a small percentage of people who take the medication. It is recommended to avoid use in patients with depression due to this risk. Seek medical help if you experience these thoughts or other changes in your behavior or mood.

Is it safe for a woman who is pregnant, about to become pregnant, or nursing to take Klonopin?

Klonopin can cause birth defects and fetal harm when taken during pregnancy. The drug may be transferred via breast milk and potentially harm a baby. Therefore, talk to your doctor if you are pregnant, planning to become pregnant, or are nursing before you take Klonopin.

Can symptoms occur if Klonopin is discontinued?

It’s important not to discontinue use of the drug before talking with your doctor. Withdrawal symptoms of Klonopin can include seizure, hallucinations, shaking, sweating, cramps, sleeping problems, changes in behavior, and anxiety.

What should I do if I overdose on Klonopin?

An overdose of Klonopin could be fatal, so seek immediate help or call the Poison Help Line at 1-800-222-1222 if you overdose. Overdose symptoms can include confusion, drowsiness, loss of consciousness, or coma.

Is Klonopin habit-forming?

Klonopin can be habit-forming, so it’s important to take the medication exactly as directed. If you have a history of substance misuse problems, talk to your doctor about the risks of taking the medication. It is important to understand the risk of improper use, and to monitor for symptoms for abuse, misuse, and addiction.

How much does Klonopin cost?

According to goodrx.com, 60 tablets of 0.5 mg Klonopin cost approximately $160. Sxity tablets of 0.5 mg generic clonazepam cost approximately $20.

Are there any disadvantages to Klonopin?

The biggest disadvantages of Klonopin are potential side effects and its habit-forming potential. Pregnant women are also typically advised not to take the medication. Klonopin is not a preferred option for older adults as it may increase risk of death with use.

DISCLAIMER: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other healthcare providers. This article mentions drugs that were FDA-approved and available at the time of publication and may not include all possible drug interactions or all FDA warnings or alerts. The author of this page explicitly does not endorse this drug or any specific treatment method. If you have health questions or concerns about interactions, please check with your physician or go to the FDA site for a comprehensive list of warnings.

Notes: This article was originally published January 5, 2017 and most recently updated September 26, 2022.

Arpimed

What Clonazepam is and what it is used for

Clonazepam is the active ingredient in Clonazepam.

Clonazepam belongs to a group of medicines called benzodiazepines.

Clonazepam is used to treat epilepsy in infants and older children and adults.

Clonazepam reduces the frequency of seizures.

Clonazepam reduces the severity of epileptic seizures.

What you need to know before you use Clonazepam

Do not take Clonazepam,

  • If you are allergic (hypersensitive) to clonazepam or any of the other ingredients of this medicine.
  • If you are allergic (hypersensitive) to other benzodiazepines, including diazepam, flurazepam, temazepam.

If you have any of these conditions, check with your doctor before using clonazepam.

Do not take Clonazepam,

  • If you have breathing problems or lung disease.
  • If you have severe liver failure.
  • If you have myasthenia gravis (muscle weakness and increased muscle fatigue).
  • If you have obstructive sleep apnea (stopping breathing during sleep)
  • If you abuse alcohol or take prescription or recreational drugs.

If you have any of these conditions, check with your doctor before using clonazepam.

Warnings and precautions

While being treated with antiepileptic drugs like clonazepam, some people have thoughts of harming themselves or committing suicide. If you experience any of these, tell your doctor immediately.

Talk to your doctor or pharmacist before taking clonazepam if:

  • If you have liver or kidney problems or impaired lung function.
  • Have you ever been depressed.
  • If you have ever had suicidal thoughts.
  • If you have recently lost a loved one.
  • If you regularly use alcohol or recreational drugs or have abused alcohol or recreational drugs in the past.
  • You suffer from spinal or cerebellar ataxia (movements become inaccurate, balance is disturbed when standing, slurred speech and rapid eye movement sleep develop).
  • You have a rare genetic blood disorder called porphyria.
  • If you are an elderly or malnourished patient, your doctor may need to adjust your dose of clonazepam.

If you have any of these conditions, check with your doctor before using clonazepam.

Drug interactions

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including OTC and herbal remedies. Clonazepam may interfere with the effects of certain drugs. Some drugs may also affect the effects of clonazepam.

The following drugs are especially important to note:

  • Other epilepsy drugs such as carbamazepine, hydantoins, phenobarbital, phenytoin, primidone, or sodium valproate.
  • Cimetidine (used to treat stomach problems and heartburn).
  • Rifampicin (an antibiotic used to treat infections).
  • Sleeping drugs.
  • Medicines used to relieve anxiety (tranquilizers).
  • Painkillers (analgesics) and drugs that reduce muscle tone (muscle relaxants).

Surgery

Tell your doctor or dentist that you are taking clonazepam if you are having surgery or dental work that requires pain relief. clonazepam and alcohol

Pregnancy and breast-feeding

It is not recommended to take clonazepam if you are pregnant, think you might be pregnant, or are breastfeeding, unless your doctor has told you to. Clonazepam has an adverse effect on fetal development during pregnancy.

Effects on ability to drive and use machines

Talk to your doctor about driving and using machines before using clonazepam, because clonazepam slows down your response rate, especially when you start taking it. If you have any doubts about your ability to perform certain activities, contact your doctor. Clonazepam affects the ability to drive vehicles, as the drug can cause drowsiness and dizziness.

  • Do not drive while taking this drug until you know how it affects you.
  • If you know that this drug affects your ability to drive, driving while taking the drug is a legal violation.
  • You will not be held liable if:
  • Clonazepam has been prescribed for medical and dental problems and,
  • You have taken clonazepam as prescribed by your doctor or as described in this package insert and,
  • Clonazepam
  • does not affect the ability to drive safely.
  • If you have any doubts about your ability to drive safely while taking clonazepam, talk to your doctor.

Development of dependence

When taking clonazepam, there is a risk of dependence, which increases with increasing dose and duration of treatment, in patients with a history of alcohol and / or drug abuse.

Important information about the ingredients of Clonazepam

Clonazepam tablets contain lactose.

If you have been told by your doctor that you have an intolerance to some sugars, check with your doctor before taking clonazepam.

How to take Clonazepam

Clonazepam should be taken exactly as directed by your doctor. If you have any doubts, then you should consult with your doctor.

  • Clonazepam should be started at a low dose and increased gradually over 2-4 weeks until the optimal maintenance dose is found to meet the patient's needs.
  • Usually, on the recommendation of a physician, the daily dose is divided into 3 doses per day in equal doses for each dose with an equal interval of time between doses.
  • If the daily dose cannot be evenly divided into several doses, take the largest dose at bedtime.
  • After reaching an effective maintenance dose, the drug can be taken in a single daily dose at bedtime.

Adults and children over 12 years old

  • The usual starting dose is 1 mg or less per day.
  • Then the dose is gradually increased (usually up to 4-8 mg per day). The maximum daily dose should not exceed 20 mg.

Old age

  • The usual starting dose is 0.5 mg or less per day.
  • Then the dose is gradually increased (usually up to 4-8 mg per day). The maximum daily dose should not exceed 20 mg.

Children under 1 year

  • The usual starting dose is 0.25 mg or less per day.
  • Then the dose is gradually increased (usually up to 0.5-1 mg per day).

Children 1 to 5 years

  • The usual starting dose is 0.25 mg or less per day.
  • Then the dose is gradually increased (usually up to 1-3 mg per day).

Children 5 to 12 years old

  • The usual starting dose is 0.5 mg or less per day.
  • Then the dose is gradually increased (usually up to 3-6 mg per day).

If you have taken more Clonazepam than recommended

  • If you have taken more clonazepam than recommended, contact your doctor or nearest hospital immediately. Take a pack of medicines with you.
  • If you have taken a large amount of clonazepam, you may experience lethargy, drowsiness, dizziness, incoordination and decreased body reaction.

If you forget to take Clonazepam

  • If you forget to take Clonazepam, skip the missed dose and take your next dose at the scheduled time.
  • Do not take a double dose to make up for a missed one.

Stopping Clonazepam

If you take clonazepam for a long time, you may develop addiction and withdrawal symptoms if you stop taking it.

  • You should talk to your doctor before you stop taking clonazepam, because if you suddenly stop taking the drug, you may have a recurrence of epileptic seizures and the development of a withdrawal syndrome. (see Possible Side Effects).
  • If you need to reduce the dose or stop taking the drug, you need to do it gradually. Your doctor will tell you how to do this.

If someone else has taken clonazepam by mistake, they should contact their doctor or the nearest hospital immediately.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Possible side effects

Like all medicines, clonazepam can cause side effects, although not everyone gets them.

Important side effects :

Allergic reactions .

If you develop an allergic reaction, call your doctor immediately.

Allergic reactions may manifest as the following symptoms:

  • Sudden swelling of the larynx, face, lips and mouth. These symptoms can lead to difficulty breathing or swallowing.
  • Sudden swelling of hands, feet and ankles.
  • Skin rash or itching.

Cardiovascular adverse reactions

If you have any of these symptoms, you should contact your doctor immediately.

These symptoms include:

  • Shortness of breath, swelling of the ankles, cough, fatigue and palpitations.
  • Pain in the chest area, which can radiate to the neck, shoulder and left arm.

Nervous system side effects

If you have any of these symptoms, you should talk to your doctor.

These symptoms include:

  • Feelings of aggression, agitation, irritability, nervousness, agitation, anxiety and hostility.
  • Sleep disturbance, nightmares and vivid dreams.
  • Hallucinations, manias and speech impairment.
  • Development of new types of seizures not previously observed

Children and infants

  • Special care should be taken when taking clonazepam in children and infants, as clonazepam may lead to respiratory dysfunction, coughing and a feeling of suffocation. This may be caused by excessive salivation.
  • Early puberty possible. After the abolition of clonazepam, this process stops.

Other possible side effects

Taking clonazepam may cause the following symptoms:

  • Drowsiness and fatigue
  • Dizziness and fatigue.
  • Muscle weakness or flexibility, jerky movements (poor coordination)
  • Walking instability

Tell your doctor if you have any of these symptoms. Your healthcare provider will prescribe you a low dose, if necessary, by gradually increasing the dose of clonazepam.

The following symptoms may occur at any time during treatment with clonazepam

  • Anxiety
  • Difficulty in remembering new things
  • Headache
  • Depression
  • Slow or broken speech
  • Poor coordination of movements, including unsteadiness when walking
  • Increased incidence of epileptic seizures
  • Circulatory, renal and hepatic system

    • Liver dysfunction (diagnosed by laboratory liver tests)
    • Uncontrolled urination
    • Problems with the circulatory system. Symptoms include feeling tired, bruising from minor concussions, shortness of breath, and nosebleeds.

    Your healthcare provider should perform periodic blood tests if necessary.

    Gastrointestinal tract

    • Nausea
    • Gastric disorders

    Organs of vision

    • Diplopia (double vision)
    • Involuntary oscillatory movements (nystagmus)

    Respiratory system

    • Respiratory failure (respiratory depression). The first signs include sudden noisy, labored and irregular breathing. The development of cyanosis of the skin is possible.

    Skin and hair

    • Skin rash, urticaria and pruritus.
    • Skin discoloration
    • Hair loss

    Sexual system

    • Libido reduction
    • Erectile dysfunction

    Syndrome Withdrawal

    When taking benzodiazepines such as clonazepam, addiction to the drug may develop. Therefore, with a sudden discontinuation or dose reduction of clonazepam, a withdrawal syndrome may develop. Withdrawal syndrome can lead to the development of the following symptoms:

    • Sleep disorder
    • Muscle pain, tremor and restlessness
    • Feelings of increased anxiety, tension, feelings of irritability or agitation, or mood changes
    • Increased sweating
    • Headache

    The following symptoms are less common:

    • Hypersensitivity to light, noise and physical contact
    • Hallucinations
    • Tingling and numbness of hands and feet
    • Feeling out of touch with reality

    Trauma

    Patients taking benzodiazepines are at an excessive risk of falling or breaking bones, especially the elderly, patients taking sedatives, including alcohol.

    Reporting side effects insert. You can also report side effects to Arpimed LLC by going to the website www.arpimed.com and filling out the appropriate form “Report a side effect or ineffectiveness of a drug” and to the Scientific Center for Expertise of Drugs and Medical Technologies named after. Academician E.Gabrielyan, by going to the website www.pharm.am in the section “Report a side effect of a drug” and fill out the form “Map of reporting a side effect of a drug”. Scientific center hotline: +37410237665; +37498773368 By reporting side effects, you help provide more information about the safety of this drug.

    How to store Clonazepam

    • The drug should be stored out of the reach of children, dry, protected from light at a temperature not exceeding 25 0
    • Shelf life - 3 years. Do not use clonazepam after the expiration date which is stated on the package. When specifying the expiration date, the last day of the specified month is meant.
    • Do not throw away leftover tablets. Ask your doctor or pharmacist how to dispose of medicines you no longer need. Keep the medicine with you if your doctor has instructed you to do so.
    • If the tablets have changed color or show other signs of deterioration, ask your pharmacist how to dispose of the medicine.

    Package contents and additional information

    What Clonazepam contains

    One tablet contains:

    active substance - clonazepam - 2 mg;

    excipients: microcrystalline cellulose, lactose monohydrate, corn starch, povidone, sodium starch glycolate, magnesium stearate, purified talc.

    What Clonazepam looks like and contents of the pack:

    White, round, flat tablets scored on one side.

    Carton containing 24 tablets (1 blister of 24 tablets) with leaflet. Klonopin and MDMA | Interactions and mixing effects

    klonopin and MDMA

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    MDMA, the full name is methylenedioxymethylamphetamine. A bit boring, so most people just call it MDMA, Ecstasy, Molly, Mum and Dad, X, E, or XTC, Disco Biscuits, Thizz, and all the other street names that might confuse the uninitiated user a bit.

    Can Klonopin and MDMA be mixed?

    Before we continue talking about Klonopin and MDMA, disclaimer : The World's Best Rehab Blog aims to improve the quality of life for people struggling with addiction and mental health issues. We use fact-based content and publish material that is researched, cited, edited and reviewed by professionals. The information we publish is not intended to replace professional medical advice, diagnosis or treatment. It should not be used as a substitute for the advice of your doctor or other qualified health care provider.

    To be honest, we don't recommend mixing Klonopin with MDMA. If you are using it for entertainment, why bother? Klonopin does not increase the effects of MDMA and can cause serious complications that will really ruin your evening. For example, death, which is always a risk when mixing MDMA and Klonopin.

    When mixed with Klonopin, MDMA may interfere with the body's ability to maintain the correct temperature. Indeed, it can also be caused by taking large amounts of MDMA without mixing it with Klonopin. Users sometimes experience a dangerous rise in body temperature (hyperthermia), which can lead to liver, kidney or heart failure, or even (as we said) death.

    klonopin and MDMA interaction

    If you're looking for an interaction between klonopin and MDMA, remember that with MDMA there's really no way to tell what it's been diluted with or mixed with. Pure MDMA, meaning it has no other substances, is not a safe drug. MDMA on its own and even without klonopin can have the same effects as other stimulants such as cocaine and amphetamines. A person taking ecstasy may experience increased heart rate and blood pressure, muscle tension, involuntary clenching of teeth, nausea, blurred vision, weakness, chills, or sweating.

    Since MDMA is not pure, you are not aware of the interaction with Klonopin in your body.

    MDMA is as likely to be mixed with other substances as any other drug. A supposedly "clean" Molly might contain ephedrine (a stimulant), dextromethorphan (a cough suppressant), ketamine, caffeine, cocaine, methamphetamine, or even bath salts. The fact that it comes in crystal or powder form and not tablets like ecstasy does not prove that it is pure. In this case, it is impossible to accurately predict the effect of mixing Klonopin and MDMA in your body. Indeed, the chemical reactions of MDMA and Klonopin in your body can be completely different from those of someone else taking exactly the same amount of Klonopin and MDMA due to individual physiology.

    According to the National Institute on Drug Abuse (NIDA), a significant percentage of molly or ecstasy contains some level of impurities. So it's not just the effects of mixing Klonopin and Molly. We are talking about mixing MDMA, klonopin and everything else that is used as a diluent.

    Common items used to cut MDMA

    • Paramethoxyamphetamine (PMA) or MDEA
    • Aspirin
    • Caffeine
    • Methamphetamine or amphetamine
    • Cocaine
    • Bath salts, including preparations such as mephedrone
    • butylone
    • Ketamine
    • LSD

    Unfortunately, the DEA also reported that “over 80 different unique substances have been sold as MDMA. Many drugs sold as "Molly" or "Ecstasy" do not contain MDMA at all." What worries you, in any case, you decide to look at it.

    klonopin and MDMA and fentanyl

    What the above list of cutting agents does not reveal is probably the most agonizing thing that has come up in the last few years. This is the widespread and unqualified use of fentanyl as a cutting agent for MDMA and other drugs. Many people now use MDMA for recreational purposes. It's illegal. And most people are informed enough to balance the risk (both prosecution and health) of taking MDMA and mixing MDMA with Klonopin.

    Most people don't haggle over a huge lethal dose of Fentanly thinking it's MDMA. Completely wrong. An unacceptable behavior in the eyes of many, but a seemingly acceptable practice for those involved in the sale and production of MDMA. When we mix fentanl with MDMA and then {fuldrug}, there's a chance of a massive myocardial infarction... a.k.a. a heart attack. And usually death.

    Isn't MDMA safe? Then surely klonopin and MDMA are also safe?

    No drug is "safe". Such is the nature of drugs! If they can be 100% avoided, then great. If not. Learn about all the facts and interactions between drugs. With regard to MDMA, there has been a lot of news recently about medically supervised clinical trials. Psilocybin and MDMA are two of the promising psychedelic drugs for mental illness treatments. A recent phase 3 trial of MDMA and talk therapy for people suffering from post-traumatic stress disorder has shown positive results. However, these are limited medical trials. They do not in any way support the use of MDMA or the mixing of Klonopin and MDMA.

    Mixing drugs is not something to be taken lightly, if you are on Klonopin and also use alcohol or weed, you can explore the effects here. Effects of klonopin and weed or effects of klonopin and alcohol or klonopin and cocaine.

    klonopin vs.

    MDMA

    MDMA vs. klonopin

    3,4-methyl Endioxy methamphetamine0839 ecstasy ) and crystalline form ( Molly or Mandy ), is a potent central nervous system (CNS) stimulant that is primarily used for recreational purposes. Desired effects include altered sensations, increased energy, empathy, and pleasure. When taken orally, effects begin in 30 to 45 minutes and last 3 to 6 hours.

    MDMA was first developed in 1912 by Merck. It has been used to enhance psychotherapy since 1970s and became popular as a street drug in the 1980s. MDMA is commonly associated with dance parties, raves and electronic dance music. It can be mixed with other substances such as ephedrine, amphetamine and methamphetamine. In 2016, about 21 million people aged 15 to 64 used ecstasy (0.3% of the world's population). This was broadly similar to the percentage of people using cocaine or amphetamines, but lower than cannabis or opioids. In the United States, as of 2017, about 7% of people have used MDMA at some point in their lives, and 0.9% used it in the last year.

    Short-term side effects include teeth grinding, blurred vision, sweating and heart palpitations, and long-term use can also lead to addiction, memory problems, paranoia, and trouble sleeping. Deaths due to fever and dehydration have been reported. After use, people often feel depressed and tired. MDMA works primarily by increasing the activity of the neurotransmitters serotonin, dopamine and norepinephrine in parts of the brain. It belongs to the substituted amphetamine drug classes and has stimulant and hallucinogenic effects.

    MDMA is banned in most countries. and has limited medical approval
    in a small number of countries. In the United States, the Food and Drug Administration is currently evaluating the drug for clinical use. Canada has allowed limited distribution of MDMA and other psychedelics such as psilocybin upon application and approval from Health Canada.

    Klonopin and MDMA overdose effects

    According to the latest data, about 119,000 people in the US alone are receiving treatment for ecstasy and MDMA related problems. In addition, one study found that 19,458 people died from psychostimulants, including MDMA, in 2019.

    But the answer to the question: "Can you overdose on ecstasy?" not quite straight forward. While it is possible to die as a result of using ecstasy, death from this drug is not necessarily a direct result of overuse, but rather due to side effects. And when klonopin and MDMA are mixed, these side effects can increase rapidly and exponentially.

    According to medical experts, direct death from MDMA and ecstasy use is usually associated with overheating. MDMA interferes with the body's ability to regulate temperature, and Klonopin further interferes with this process. When people are then in warm conditions or dancing, the risk of overheating is higher. The medical term for this is hyperthermia, and with hyperthermia people are at increased risk:

    • Dehydration
    • Cerebral edema
    • Muscle disorder
    • Electrolyte imbalance
    • Violation of the organ

    klonopin and MDMA for emergencies

    Many ecstasy "overdoses" are a direct result of additives in the pills themselves, such as the fentanly we talked about earlier. When MDMA users arrive at a hospital or rehab center, doctors and staff are not immediately aware of what percentage of the pills they ingested was MDMA compared to other supplements, or what other substances (legal or illegal) were ingested, such as Klonopin. and MDMA. This requires a blood toxicology test, and while the results are pending, healthcare professionals will do their best to treat dehydration and overheating. 1 https://www. ncbi.nlm.nih.gov/pmc/articles/PMC3931692/.

    When the patient's condition stabilizes, there is a good chance of a full recovery. However, some cases of ecstasy overdose can be fatal, especially when using fentanyl and other very dangerous cutting agents.

    If you've used MDMA and ecstasy and find it hard to stop, it's probably time to get help. Don't risk overdosing or developing a chronic addiction.

    If you are taking klonopin and also use alcohol or MDMA, you can investigate the effects of klonopin and alcohol as well as the signal of klonopin and weed and klonopin and cocaine here.

    For the effects of other drugs and weeds, refer to our Weeds and Other Drugs List A to L or our Weeds and Other Drugs List MZ.

    Or you can find what you are looking for in our A to L Alcohol and Other Drugs Index or M to Z Alcohol and Other Drugs Index or our A to L MDMA and Other Drugs Index or MDMA and Others Index drugs from M to Z, or Cocaine and other drugs Index from A to L or Index of cocaine and other drugs from M to Z.

    To find information about the rehabilitation of drug addicts and drug addicts around the world

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    If you want to stop taking MDMA or Klonopin, you may experience withdrawal symptoms. MDMA withdrawal can be explored here, and Klonopin withdrawal can be found on our Withdrawal Index.

    Find the best rehabs near you to help you treat or manage your addiction

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    Links: Klonopin and MDMA

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