St john's wort and adderall

Other Medications, Alcohol, and More

Adderall (amphetamine/dextroamphetamine) is a prescription drug that’s used to treat attention deficit hyperactivity disorder (ADHD) in adults and some children. Adderall is also used to treat narcolepsy. Like other drugs, Adderall may have interactions.

Some interactions occur because one substance causes another substance to have a different effect than expected. For example, sometimes alcohol, another drug, or a supplement can affect how a drug acts in your body. Interactions can also occur if you have certain health conditions.

Keep reading to learn about Adderall’s possible interactions. And for more information about Adderall, including details about its uses, see this article.

Adderall vs. Adderall XR

There are two forms of Adderall available: Adderall and Adderall XR. Adderall is the immediate-release form of the drug. This means that after you take a dose, the drug begins working right away. But the drug’s effects don’t last all day. Some people may only need to take Adderall once per day, while others may take it every 4 to 6 hours.

On the other hand, Adderall XR is an extended-release form of the drug. That means the drug is slowly released into your body over time to manage your ADHD symptoms. Adderall XR is only taken once daily.

Adderall and Adderall XR contain the same active ingredients, amphetamine and dextroamphetamine. This means they also have the same interactions. But this article focuses on Adderall only.

To learn more about Adderall XR, talk with your doctor.

Certain health conditions or other factors could raise your risk of harm if you take Adderall. In that case, your doctor may not prescribe Adderall for you. This is known as a contraindication. The list below includes contraindications of Adderall.

If you have a history of drug misuse. Adderall has a risk of misuse and dependence. In fact, the drug has a boxed warning for this risk. (To learn more, see the “Boxed warning” section at the beginning of this article. ) If you’ve misused or been dependent on drugs before, your doctor may recommend a drug other than Adderall.

If you have heart disease or high blood pressure. Adderall may raise your risk of heart problems or high blood pressure. If you already have heart disease or high blood pressure, taking Adderall could worsen your condition. If you have one of these conditions, talk with your doctor before taking Adderall. Your doctor will likely recommend a different drug for you.

If you have hyperthyroidism. If you have hyperthyroidism (overactive thyroid), your doctor will likely treat this condition before prescribing Adderall. This is because Adderall can make the symptoms of an overactive thyroid even worse.

If you have glaucoma. Adderall can cause increased eye pressure. If you have glaucoma, taking Adderall may make your condition worse. Your doctor will likely recommend a drug other than Adderall for your condition.

If you have agitation. If you have agitation, your doctor may recommend a drug other than Adderall for you. This is because Adderall may make your agitation worse.

If you’ve recently taken a monoamine oxidase inhibitor (MAOI). Your doctor will not prescribe Adderall if you’re currently taking an MAOI or have taken one in the past 14 days. This is because taking an MAOI with Adderall may raise your risk of serious high blood pressure, which can even be life threatening. To help prevent this interaction, you should wait at least 14 days after your last dose of an MAOI before taking Adderall. Examples of MAOIs may include:

• phenelzine (Nardil)
• methylene blue (ProvayBlue)
• selegiline (Emsam)
• tranylcypromine (Parnate)
• isocarboxazid (Marplan)

If you’ve had an allergic reaction. If you have had an allergic reaction to Adderall or any of its ingredients, your doctor likely won’t prescribe Adderall. You can ask them about other treatments that may be better options for you.

Before you start taking Adderall, talk with your doctor if any of the factors above apply to you. Your doctor can determine whether Adderall is safe for you to take.

Adderall may interact with alcohol. It’s best to avoid alcohol while you’re taking Adderall. This is because alcohol can raise your risk of certain side effects from Adderall. For example, both Adderall and alcohol can both cause high blood pressure or fast or irregular heartbeat. Combining alcohol and Adderall can raise your risk of these side effects. Or it could make these side effects more severe if you do experience them.

In addition, alcohol may worsen symptoms of attention deficit hyperactive disorder (ADHD), which Adderall is used to treat.

Drinking alcohol while taking Adderall may decrease the effects that you feel from alcohol. This may cause you to drink more than usual, which can be dangerous.

If you drink alcohol, talk with your doctor before taking Adderall.

Before you start taking Adderall, tell your doctor and pharmacist about any prescription, over-the-counter, or other drugs you take. Sharing this information with them may help prevent possible interactions.

If you have questions about drug interactions that may affect you, talk with your doctor or pharmacist.

The chart below lists drugs that may interact with Adderall. Keep in mind that this chart does not include all drugs that may interact with Adderall. For more information about some of these interactions, see the “Drug interactions explained” section below.

Drug group or drug name	Drug examples	What can happen
Alkalinizing agents	• acetazolamide • sodium bicarbonate	• Can increase the effects of Adderall • Can raise the risk of side effects from Adderall
Tricyclic antidepressants (TCAs)	• doxepin (Silenor) • desipramine • (Norpramin) • amitriptyline • nortriptyline (Pamelor)	• Can increase the risk of serotonin syndrome • Can increase the effects of Adderall or TCAs
Selective serotonin reuptake inhibitors (SSRIs)	• fluoxetine (Prozac) • sertraline (Zoloft) • citalopram (Celexa) • paroxetine (Paxil)	Can raise the risk of side effects from Adderall and SSRIs
Serotonin Norepinephrine reuptake inhibitors (SNRIs)	• duloxetine (Cymbalta) • venlafaxine (Effexor XR) • desvenlafaxine (Pristiq)	Can increase the risk of side effects from Adderall and SNRIs
Quinidine		Can increase the risk of side effects from Adderall and Quinidine
Ritonavir (Norvir)		Can raise the risk of side effects from Adderall and Ritonavir
Triptans	• sumatriptan (Imitrex) • zolmitriptan (Zomig) • eletriptan (Relpax) • rizatriptan (Maxalt)	Can increase the risk of side effects from Adderall and triptans
Certain opioids	• tramadol (Ultram) • fentanyl (Subsys) • meperidine (Demerol)	Can raise the risk of side effects from Adderall and certain opioids. Adderall can also increase the effects of Meperidine.
Lithium (Lithobid)		Can increase the risk of side effects from Adderall and lithium Can make Adderall less effective
Buspirone		Can raise the risk of side effects from Adderall and buspirone
Monoamine oxidase inhibitors (MAOIs)	• tranylcypromine (Parnate) • isocarboxazid (Marplan) • methylene blue (ProvayBlue) • selegiline (Emsam)	Can raise the risk of serious side effects from Adderall and MAOIs. Due to this risk, your doctor will not prescribe an MAOI with Adderall. For more information, see “When should I avoid Adderall?” above.
Chlorpromazine		Can make Adderall less effective
Ethosuximide (Zarontin)		Can make ethosuximide less effective
Haloperidol (Haldol)		Can make Adderall less effective
Certain seizure medications	• phenobarbital • phenytoin (Dilantin) • topiramate (Topamax)	Can make your seizure medication less effective
Proton pump inhibitors	• omeprazole (Prilosec) • esomeprazole (Nexium) • pantoprazole (Protonix)	Can make Adderall less effective
Antacids	• sodium bicarbonate (Alka-Seltzer) • magnesium hydroxide • calcium carbonate (Tums)	Can increase your risk of side effects from Adderall
h3 Blockers	• cimetidine (Tagamet HB) • ranitidine (Zantac) • famotidine (Pepcid AC)	Can raise your risk of side effects from Adderall
Bupropion (Wellbutrin SR)		Can increase your risk of side effects from bupropion
Phentermine (Adipex-P)		Can raise your risk of side effects from Adderall and phentermine
Trazodone		Can increase your risk of side effects from Adderall and trazodone
Atomoxetine (Straterra)		Can raise your risk of side effects from Adderall and atomoxetine
blood pressure drugs	• propranolol (Inderal LA, InnoPran XL) • metoprolol succinate (Toprol XL) • losartan (Cozaar) • lisinopril (Zestril)	Can make your blood pressure medication less effective

Learn more about certain drug interactions that can occur with Adderall.

Interaction with serotonin norepinephrine reuptake inhibitors (SNRIs)

Adderall may interact with certain antidepressants, such as SNRIs. See the chart below for details.

What could happen	Examples of SNRIs	What you can do
Can cause serotonin syndrome, a drug reaction that can be dangerous	• duloxetine (Cymbalta) • venlafaxine (Effexor XR) • desvenlafaxine (Pristiq)	Before taking Adderall, your doctor will discuss the risk of serotonin syndrome with you. During your Adderall treatment, watch for symptoms of serotonin syndrome, including agitation, confusion, or twitching muscles. If you develop symptoms, call your doctor right away or go to the hospital.

Interaction with Bupropion (Wellbutrin SR)

Adderall may interact with bupropion, which is an antidepressant. Learn more in the chart below.

What could happen	What you can do
Can raise your risk of having a seizure, especially if you’ve had seizures in the past	Your doctor may monitor your seizure risk closely while you take Adderall with Wellbutrin. In some cases, they may recommend that you take a drug other than Adderall to treat your condition

Interaction with atomoxetine (Stratera)

Adderall and atomoxetine may interact, as described below.

What could happen	What you can do
Can raise the risk of high blood pressure	Due to this risk, your doctor will likely monitor your blood pressure closely while you’re taking both Adderall and Strattera. Or if they determine it’s not safe for you to take Adderall and Strattera together, they’ll recommend other treatment options.

Adderall may have other interactions. They could occur with supplements, foods, vaccines, or even lab tests. See below for details.

Does Adderall interact with supplements?

Before you start taking Adderall, talk with your doctor and pharmacist about any supplements, herbs, and vitamins you take. Sharing this information with them may help you avoid possible interactions.

Adderall may interact with a supplement containing tryptophan. This is because tryptophan increases the amount of serotonin in your body. And taking this with Adderall may increase your risk of serotonin syndrome occurring.

If you have questions about interactions that may affect you, talk with your doctor or pharmacist.

Adderall interactions with herbs

Adderall can interact with an herbal supplement called St. John’s wort, which may be used to treat depression.

Taking Adderall with St. John’s wort can raise your risk of serotonin syndrome, a drug reaction that can be dangerous. Due to this risk, your doctor may recommend that you stop using St. John’s wort during your Adderall treatment.

If you have questions about this interaction, talk with your doctor or pharmacist.

Adderall interactions with vitamins

Adderall may interact with vitamin C. Taking Adderall with vitamin C could make Adderall less effective. Due to this risk, your doctor may recommend spacing out your doses of Adderall and vitamin C by at least 1 hour to prevent this interaction.

Does Adderall interact with food?

Adderall can interact with caffeine. This is because both Adderall and caffeine have stimulant effects. When used together, this can raise your risk of certain side effects from the medication, including anxiety or a fast heartrate. Due to this risk, your doctor may recommend limiting your caffeine during your Adderall treatment.

Examples of foods and drinks that may contain caffeine include:

• coffee
• chocolate
• soda
• some dietary supplements
• teas, including green tea

Does Adderall interact with lab tests?

Adderall may interfere with a urine test used to check your corticosteroid levels. Your doctor may order this test if they’re trying to see how well your adrenal glands are working.

If you need to have a urinary steroid test done, it’s important that your doctor knows you’re taking Adderall.

Does Adderall interact with cannabis or CBD?

Cannabis (marijuana) and cannabis products, such as cannabidiol (CBD), have not been specifically reported to interact with Adderall.

Before you start treatment with Adderall, tell your doctor and pharmacist if you take cannabis. By sharing this information with them, you may help prevent possible interactions.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

Certain medical conditions or other health factors may raise the risk of interactions with Adderall. Before taking Adderall, talk with your doctor about your health history. They’ll determine whether Adderall is right for you.

Health conditions or other factors that might interact with Adderall include:

• Tourette syndrome or tics. Tell your doctor if you have Tourette syndrome or tics. Adderall may worsen the symptoms of these conditions. During your Adderall treatment, your doctor may monitor you closely to make sure the drug isn’t making the symptoms of your condition worse.
• Blood circulation problems. Adderall may decrease your blood circulation, especially to your fingers or toes. If you already have a condition that affects blood circulation, such as Raynaud’s phenomenon, Adderall may make your condition worse. Your doctor can determine if Adderall is a safe treatment option for you.
• Heart problems, including high blood pressure. Adderall can raise your risk of heart problems, including heart attack or stroke. If you already have heart problems, taking Adderall could make them worse. Before taking Adderall, tell your doctor about any heart problems you have. They may monitor your heart during your treatment. In some cases, they may recommend a drug other than Adderall for you.
• Glaucoma. Adderall can cause increased eye pressure. If you have glaucoma, taking Adderall may make your condition worse. Your doctor will likely recommend a drug other than Adderall for your condition.
• Mood disorders. If you have certain mood disorders, such as anxiety or bipolar disorder, Adderall could worsen your condition. Due to this risk, your doctor may recommend a drug other than Adderall for you.
• Seizures. If you have a seizure disorder, taking Adderall could raise your risk of a seizure. If you’ve had seizures before, your doctor can determine whether it’s safe for you to take Adderall. And if you have a seizure while taking Adderall, your doctor will have you stop taking the drug and switch to a different treatment.
• Thyroid problems. Adderall may make symptoms of hyperthyroidism (overactive thyroid) worse. For example, both Adderall and hyperthyroidism can cause a fast heart rate. Your doctor will likely treat your thyroid condition before prescribing Adderall.
• Pregnancy. It’s not known if it may be safe to take Adderall during pregnancy. If you’re pregnant or planning to become pregnant, talk with your doctor before taking Adderall.
• Breastfeeding. You should not breastfeed while taking Adderall. Adderall passes into breast milk and can cause side effects in a breastfed child. If you’re breastfeeding or planning to breastfeed, talk with your doctor about your options.
• Past drug dependence or misuse. Adderall has a risk of misuse and dependence. In fact, the drug has a boxed warning for this risk. (To learn more, see the “Boxed warning” section above.) If you’ve misused or been dependent on drugs before, your doctor may recommend a drug other than Adderall.
• Allergic reaction. If you’ve had an allergic reaction to Adderall or any of its ingredients, your doctor will likely not prescribe Adderall. You can ask them about other treatments that may be better choices for you.

Find answers to some frequently asked questions about Adderall and possible interactions.

Does Adderall interact with benzodiazepines?

Adderall isn’t known to interact with benzodiazepines. Benzodiazepines are a group of drugs that can be used to treat anxiety. Examples of benzodiazepines include:

• clonazepam (Klonopin)
• Alprazolam (Xanax)
• Lorazepam (Ativan)

It’s important to note that clonazepam can also be used to treat certain seizure disorders. Adderall may raise your risk of seizures. If you’re using clonazepam for a seizure disorder, talk with your doctor before taking Adderall. They can determine if it’s safe for you to take these drugs together.

Is it safe to take Adderall with gabapentin (Neurontin)?

It should be safe to take gabapentin with Adderall. There aren’t any known interactions between these drugs.

Gabapentin is a drug used to treat nerve pain or to manage seizure disorders. Adderall may raise your risk of seizures. If you take gabapentin for a seizure disorder, talk with your doctor before taking Adderall. They can determine if these drugs are safe to take together.

Can I take Adderall with Abilify?

Yes, you can likely take Adderall with aripiprazole (Abilify). These drugs are not known to interact with each other.

Abilify is a drug that treats certain mood disorders, such as bipolar disorder or major depressive disorder. If you have other questions about taking these drugs together, talk with your doctor or pharmacist.

Can I take Adderall with the supplement lion’s mane?

There aren’t any reported interactions between Adderall and the mushroom supplement lion’s mane. Lion’s mane may be used to treat anxiety, depression, or nerve problems.

If you’re interested in taking lion’s mane during your Adderall treatment, talk with your doctor or pharmacist.

Taking certain steps can help you avoid interactions with Adderall. Before starting treatment, talk with your doctor and pharmacist. Things to discuss with them include:

• Whether you drink alcohol or use cannabis.
• Other medications you take, as well as any vitamins, supplements, and herbs. Your doctor or pharmacist can help you fill out a medication list.
• What to do if you start taking a new drug during your Adderall treatment.

It’s also important to read Adderall’s label and other paperwork that comes with the drug. You may see colored stickers on the label that describe interactions. And the paperwork (sometimes called the prescribing information) may have other details about interactions. If you need help understanding this information, your doctor or pharmacist can help.

Taking Adderall exactly as prescribed can also help prevent interactions.

If you still have questions about Adderall and its possible interactions, talk with your doctor.

Questions you may want to ask your doctor include:

• Does my risk of interactions depend on my Adderall dosage?
• Do other drugs for ADHD or narcolepsy have the same interactions as Adderall?
• Should I tell you if I start taking another medication or supplement while I’m taking Adderall?
• Could I still take Adderall even if it interacts with a health condition I have?

If you take Adderall for ADHD, you can learn more about your condition by signing up for Healthline’s ADHD newsletter.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Adderall and interactions: Supplements, alcohol, and more

Adderall (amphetamine/dextroamphetamine) is a brand-name prescription drug used to treat attention deficit hyperactivity disorder (ADHD). It’s also used to treat narcolepsy.

As with other medications, Adderall can interact with alcohol and certain other drugs. It can also interact with some supplements and foods. An interaction occurs when one substance causes another substance to have a different effect than expected.

For more about Adderall’s interactions, keep reading. For additional information about Adderall, including details about its uses, see this article.

In some cases, a factor or condition could prevent your doctor from prescribing Adderall due to the risk of harm. This is known as a contraindication. The contraindications of Adderall include the ones mentioned below.

If you have a serious heart or blood vessel problem. Taking Adderall can increase your heart rate and blood pressure. If you have a serious heart or blood vessel problem, the side effects could lead to heart attack or stroke. The side effects could also, in rare cases, lead to sudden death. In addition, Adderall could make your condition worse. Examples of serious heart and blood vessel problems include:

• moderate to severe hypertension (high blood pressure)
• advanced arteriosclerosis (hardening of the arteries)
• heart disease that causes symptoms such as chest pain or shortness of breath

If you have hyperthyroidism. Taking Adderall can increase your heart rate and blood pressure. Hyperthyroidism (an overactive thyroid gland) can also cause these symptoms. If you have hyperthyroidism, Adderall could worsen your symptoms.

If you have glaucoma. Adderall can increase the pressure in your eyes. If you have glaucoma, taking Adderall could worsen your condition.

If you have had an allergic reaction to Adderall or any of its ingredients. If you’ve had an allergic reaction to Adderall or any of its ingredients, taking the drug could cause such a reaction. You could also have an allergic reaction with Adderall if you’ve had such a reaction to other drugs called amphetamines. (Adderall is a type of amphetamine.)

If you’re in an agitated state. If you’re in an agitated state, taking Adderall could worsen it. Agitation refers to feeling restless, nervous, or annoyed. Sometimes it can be due to a mental health condition.

If you have a history of drug misuse or dependence. Adderall has a risk of misuse and dependence. If you’ve misused or been dependent on drugs in the past, you may have an increased risk of these problems with Adderall. In fact, the drug has a boxed warning about this risk. This is a serious warning from the Food and Drug Administration (FDA). To learn more, see “Boxed warning: Risk of misuse and dependence” at the top of this article.

If you have recently taken a monoamine oxidase inhibitor drug. Monoamine oxidase inhibitors (MAOIs) are an older class of antidepressant drugs. Adderall typically should not be taken within 14 days of taking an MAOI drug. Doing so can cause dangerous side effects, including kidney failure, heart attack, and unsafe rises in blood pressure.

If you’ve taken an MAOI recently, be sure to let your doctor know. They may still prescribe Adderall. However, they’ll likely have you wait at least 14 days from your last dose of the MAOI before you start Adderall treatment.

To learn more, see “Drug interactions in depth” below.

Note: Before you start treatment with Adderall, it’s important to tell your doctor if any of these factors apply to you. They can determine whether to prescribe Adderall.

Adderall may interact with alcohol. For example, drinking alcohol with Adderall can reduce the effects of alcohol, so you may drink more than you usually would. This can have dangerous results, such as loss of consciousness.

Drinking alcohol while taking Adderall may also increase the risk of certain side effects of the drug. These can include increased blood pressure and a fast or irregular heartbeat. Such side effects can increase your risk of heart attack or stroke.

Drinking alcohol can also worsen symptoms of attention deficit hyperactivity disorder (ADHD), which Adderall is used to treat.

If you drink alcohol, talk with your doctor about how much is safe to drink with Adderall. However, in general, it’s safest to avoid drinking alcohol while you take the medication.

Before you start treatment with Adderall, tell your doctor and pharmacist which prescription, over-the-counter, and other medications you take. By sharing this information with them, you may help prevent possible interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Here’s a chart of drugs that can interact with Adderall. Keep in mind that this chart does not include all drugs that may interact with Adderall. Some of these interactions are described in detail below in “Drug interactions in depth.”

Drug class or drug name	Drug examples	Interaction result with Adderall
monoamine oxidase inhibitors (MAOIs)*	• isocarboxazid (Marplan) • linezolid (Zyvox) • phenelzine (Nardil) • selegiline (Emsam, Zelapar) • tranylcypromine (Parnate)	can cause dangerous side effects
tricyclic antidepressants (TCAs)	• amitriptyline • desipramine (Norpramin) • imipramine (Tofranil)	can increase the risk of serotonin syndrome and heart-related side effects from Adderall
selective serotonin reuptake inhibitors (SSRIs)	• citalopram (Celexa) • escitalopram (Lexapro) • fluoxetine (Prozac) • fluvoxamine (Luvox) • paroxetine (Paxil, Brisdelle, Pexeva) • sertraline (Zoloft)	can increase the risk of serotonin syndrome
serotonin noradrenaline reuptake inhibitors (SNRIs)	• desvenlafaxine (Pristiq) • duloxetine (Cymbalta) • venlafaxine (Effexor XR)	can increase the risk of serotonin syndrome
triptans	• almotriptan • eletriptan (Relpax) • frovatriptan (Frova) • naratriptan (Amerge) • rizatriptan (Maxalt, Maxalt-MLT) • sumatriptan (Imitrex, Tosymra, others)	can increase the risk of serotonin syndrome
lithium (Lithobid)	—	can increase the risk of serotonin syndrome
buspirone†	—	can increase the risk of serotonin syndrome
mirtazapine (Remeron)	—	can increase the risk of serotonin syndrome
certain opioids	• fentanyl (Subsys, Fentora, Lazanda, Actiq) • tramadol (ConZip, Ultram, Qdolo)	can increase the risk of serotonin syndrome
cytochrome p450 2D6 (CYP2D6) inhibitors	• fluoxetine (Prozac) • paroxetine (Paxil, Brisdelle, Pexeva) • quinidine • ritonavir (Norvir)	can increase the risk of side effects from Adderall
antacids	• calcium carbonate (TUMS) • sodium bicarbonate (Alka-Seltzer) • magnesium hydroxide/calcium carbonate (Rolaids)	can increase the risk of side effects from Adderall
h3 blockers	• cimetidine (Tagamet HB) • famotidine (Pepcid AC) • nizatidine (Axid) • ranitidine (Zantac)	can increase the risk of side effects from Adderall
urinary alkalinizers	• acetazolamide	can increase the risk of side effects from Adderall
proton pump inhibitors	• esomeprazole (Nexium) • lansoprazole (Prevacid) • omeprazole (Prilosec) • pantoprazole (Protonix) • rabeprazole (Aciphex)	can make Adderall less effective than usual
bupropion (Wellbutrin SR, Wellbutrin XL)	—	can increase the risk of seizures

* To learn more, see “When to avoid Adderall” above.
† Buspar, a brand-name version of buspirone, used to be available but has been discontinued.

Here’s a closer look at certain drug interactions with Adderall.

Serotonergic drugs

Serotonergic drugs are drugs that increase levels of the chemical serotonin in your body.

Interaction result. Increased risk of serotonin syndrome.

Interaction explained. Adderall and serotonergic drugs can increase levels of serotonin in your body. Taking Adderall with a serotonergic drug can cause your serotonin level to rise too much, leading to serotonin syndrome.

Examples of serotonergic drugs. Here are some serotonergic drugs:

• selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine (Prozac)
• serotonin noradrenaline reuptake inhibitors (SNRIs), such as venlafaxine (Effexor XR)
• tricyclic antidepressants, such as amitriptyline
• certain other antidepressants, such as mirtazapine (Remeron)
• triptans for migraine, such as sumatriptan (Imitrex)
• the anxiety drug buspirone
• lithium (Lithobid)
• certain opioids, such as fentanyl (Subsys, Fentora, Lazanda, Actiq)

Steps you or your doctor may take. If you take Adderall with a serotonergic drug, your doctor may prescribe a dosage of Adderall that’s lower than usual. See your doctor right away if you have symptoms of serotonin syndrome while taking Adderall with a serotonergic drug.

Symptoms of serotonin syndrome can include dry mouth, dilated pupils, hallucinations, and sweating more than usual. Other symptoms can include a very high body temperature, stiff muscles, and delirium (sudden confusion about what’s real).

Monoamine oxidase inhibitors

Adderall has a serious interaction with drugs called monoamine oxidase inhibitors (MAOIs). These include MAOI antidepressants, and certain drugs for Parkinson’s disease or infections.

Interaction result. Risk of dangerous side effects.

Interaction explained. Taking Adderall with an MAOIcan cause a hypertensive crisis (a dangerous increase in blood pressure), heart attack, or stroke. The drug combination can also cause serotonin syndrome. This is a serious condition caused by a buildup of the chemical serotonin in your body. (To learn about symptoms of serotonin syndrome, see “Serotonergic drugs” above.)

Examples of MAOI drugs. Here are some MAOIs:

• isocarboxazid (Marplan)
• linezolid (Zyvox)
• methylene blue (ProvayBlue)
• phenelzine (Nardil)
• selegiline (Emsam, Zelapar)
• tranylcypromine (Parnate)

Steps you or your doctor may take. Adderall typically should not be taken within 14 days of taking an MAOI drug. If you’ve taken an MAOI recently, be sure to let your doctor know. They may still prescribe Adderall. However, they’ll likely have you wait at least 14 days from your last dose of the MAOI before starting Adderall treatment.

Acid-reducing drugs

Acid-reducing drugs reduce the level of acid in your stomach. The medications are used to treat conditions such as indigestion, heartburn, or stomach ulcers.

Interaction result. Increased risk of side effects from Adderall.

Interaction explained. Acid-reducing drugs can increase the absorption of Adderall into your body. This can raise the level of Adderall in your blood, which can make side effects from Adderall more likely.

Examples of acid-reducing drugs. Here are some acid-reducing drugs:

• antacids, such as calcium carbonate (TUMS)
• h3 blockers, such as famotidine (Pepcid AC)
• proton pump inhibitors, such as esomeprazole (Nexium)

Steps you or your doctor may take. If you take Adderall with an acid-reducing drug, your doctor may prescribe a dosage of Adderall that’s lower than usual. Also, keep in mind that you should not take antacids at the same time of day as Adderall.

Adderall may have other interactions, such as with supplements, herbs, or foods. You’ll find details below.

Adderall interactions with supplements

Before you start treatment with Adderall, tell your doctor and pharmacist which supplements, herbs, and vitamins you take. By sharing this information with them, you may help prevent possible interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Adderall interaction with supplements

Certain supplements can raise the level of the chemical serotonin in your body. Taking Adderall with one of these supplements can increase your risk of serotonin syndrome. This is a serious condition caused by a buildup of serotonin in your system.

Examples of these supplements include tryptophan and 5-HTP (5-hydroxytryptophan).

Adderall interactions with herbs

An herb called St. John’s wort can increase the level of serotonin in your body. Taking Adderall with St. John’s wort can increase your risk of serotonin syndrome.

Adderall interactions with vitamins

Taking Adderall with vitamin C can reduce the absorption of Adderall into your body. This could make Adderall less effective than usual. You should take vitamin C and Adderall at least 1 hour apart.

Adderall interactions with food

Adderall has stimulant effects. If you consume caffeine with Adderall, this may increase the stimulant effects of the drug. This could cause or worsen Adderall side effects such as trouble sleeping, anxiety, and increased heart rate.

You should avoid consuming large amounts of caffeine with Adderall. Caffeine is found in several foods and drinks, such as:

• tea, including green tea
• coffee
• chocolate
• cola drinks

Adderall and cannabis or CBD

Cannabis (marijuana) and cannabis products, such as cannabidiol (CBD), have not been specifically reported to interact with Adderall. However, as with any drug or supplement, talk with your doctor before taking cannabis in combination with Adderall. The impact of cannabis may affect how well you stick to your Adderall treatment plan.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

Certain medical conditions and other factors may increase the risk of interactions with Adderall. Before you take Adderall, be sure to talk with your doctor about your health history. Adderall may not be the right treatment option if you have certain medical conditions or other factors affecting your health. These include:

• High blood pressure. Adderall can increase your blood pressure. If you have mildly high blood pressure, Adderall could make it worse. If you have moderately or severely high blood pressure, your doctor will likely not prescribe Adderall. To learn more, see “When to avoid Adderall” above.
• Heart conditions. Adderall can increase your heart rate and blood pressure. If you have a heart condition, Adderall could make it worse. Your doctor may check your heart function before prescribing Adderall to make sure the drug is safe for you. If you have a serious heart condition, your doctor will likely not prescribe Adderall. To learn more, see “When to avoid Adderall” above.
• Circulation problems. Adderall can decrease blood flow to your fingers and toes. If you have a circulation problem such as Raynaud’s disease, taking Adderall could worsen your symptoms.
• Mental health conditions. If you have a mental health condition such as bipolar disorder, anxiety, psychosis, or schizophrenia, taking Adderall could worsen your symptoms.
• Tourette’s syndrome or tics. If you haveTourette’s syndrome or tics affecting movements or speech, taking Adderall could worsen your symptoms.
• Seizures. If you have a seizure disorder, taking Adderall could increase your risk of having a seizure.
• Allergic reaction. If you’ve had an allergic reaction to Adderall or any of its ingredients, taking the drug could cause such a reaction. You could also have an allergic reaction with Adderall if you’ve had such a reaction to other drugs called amphetamines. (Adderall is a type of amphetamine.)
• Hyperthyroidism. Taking Adderall can increase your heart rate and blood pressure. Hyperthyroidism can also cause these symptoms. If you have hyperthyroidism, Adderall could worsen your symptoms.
• Glaucoma. Adderall can increase the pressure in your eyes. If you have glaucoma, taking Adderall could worsen your condition.
• Agitation. If you’re in an agitated state, taking Adderall could worsen it. Agitation refers to feeling restless, nervous, or annoyed. Sometimes it can be due to a mental health condition.
• Past drug misuse or dependence. Adderall has a risk of misuse and dependence. If you’ve misused or been dependent on drugs in the past, you may have an increased risk of these problems with Adderall. In fact, the drug has a boxed warning about this risk. This is a serious warning from the Food and Drug Administration (FDA). To learn more, see “Boxed warning: Risk of misuse and dependence” at the top of this article.
• Pregnancy. It’s not known if Adderall is safe to take during pregnancy.
• Breastfeeding. You should not take Adderall if you’re breastfeeding. The drug can pass into breast milk and cause side effects in a child who is breastfed.

Here are some frequently asked questions about Adderall and possible interactions.

Does Adderall interact with antihistamines?

Adderall is not known to interact with antihistamines (medications that treat allergies). However, some antihistamines can make you feel drowsy. Examples include chlorpheniramine and diphenhydramine (Benadryl). Adderall tends to make you more alert than usual. So if you take it with one of these antihistamines, Adderall may reduce drowsiness from the antihistamine.

It’s generally considered safe to take Adderall with antihistamines. If you have additional questions about taking these medications together, talk with your doctor or pharmacist.

Can you take gabapentin and Adderall together?

Adderall is not known to interact with gabapentin (Neurontin, Gralise, Horizant). Gabapentinis a seizure medication that’s also prescribed for nerve pain.

However, if you take gabapentin to help prevent seizures, it’s important to note that Adderall can increase your risk of having a seizure. This means that gabapentin may not work as well as usual to help prevent seizures if you take it with Adderall.

Your doctor and pharmacist can help answer other questions you have about Adderall and gabapentin.

Are there interactions between Adderall and Ativan or Klonopin?

There are no known interactions between Adderall and lorazepam (Ativan) or clonazepam (Klonopin). They can be used together safely if you take them as your doctor prescribes.

Ativan and Klonopin are a type of drug called benzodiazepines and are used to relieve anxiety. Adderall is sometimes prescribed with these drugs for people who have both anxiety and attention deficit hyperactivity disorder (ADHD).

Klonopin is sometimes also used to help prevent certain types of seizures. It’s important to note that Adderall can increase your risk of having a seizure. This means Klonopin may not work as well as usual to help prevent seizures if you take it with Adderall.

If you’re interested in taking Adderall with Ativan or Klonopin, talk with your doctor. They can advise you on the right treatment plan for you.

You can take certain steps to help prevent interactions with Adderall. Your doctor and pharmacist are key resources, so reach out to them before starting treatment. For example, you should plan the following:

• Let them know if you drink alcohol or take cannabis.
• Tell them about any other medications you take, as well as any supplements, herbs, and vitamins.
• Create a medication list, which your doctor and pharmacist can help you fill out.
• Check with your doctor or pharmacist before taking any new medications, supplements, herbs, or vitamins while you’re taking Adderall.

It’s also important to read the label of Adderall and other paperwork that comes with the drug. The label may have colored stickers that mention an interaction. And the paperwork, sometimes called the prescribing information, may contain details about interactions. If this information is difficult to understand, ask your doctor or pharmacist to help explain it.

You can also help prevent interactions with Adderall by taking it exactly as your doctor prescribes.

Besides learning about interactions, you may want to find out more about Adderall. These resources might help:

• Overview of Adderall. For a general overview of Adderall, you can see this article.
• Side effects. If you’re interested in the side effects of Adderall, see this article. Another option is to refer to the prescribing information for Adderall and Adderall XR.
• Drug comparison. For information abouthow Adderall compares with other drugs such as modafinil, Strattera, and methylphenidate, see this article. You can also find information about how Adderall compares with the following medications:
  • Dexedrine
  • Vyvanse
  • Ritalin
  • Concerta
  • guanfacine
• Facts about your condition. To learn more about attention deficit hyperactivity disorder (ADHD), see our list of related articles. For more information about narcolepsy, you can visit our science of sleep hub and list of sleep articles.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Incredible Adventures of Books in 2022: What to Read in the Next Twelve Months

Incredible Adventures of Books in 2022: What to Read in the Next Twelve Months

Incredible adventure books in 2022:

Text: Polina Boyarkina, Elena Vasilyeva

It is becoming more and more difficult to publish books in Russia, but even in cramped circumstances, publishers are making ambitious plans. "Reading" polled more than twenty publishers to make sure that you won't be bored in the coming year.

Corpus continues to republish books by Vladimir Nabokov, in company with Eduard Limonov in Alpina. Prose” was attended by Lyudmila Petrushevskaya, Pavel Pepperstein and Lena Eltang, “Gorodets” will publish three volumes of texts by Dmitry Danilov and Pavel Krusanov. Elena Shubina's Editorial Office is preparing new books by popular contemporary prose writers: a collection of short stories by Dmitry Bykov, a novel by Evgeny Vodolazkin, works by Andrei Rubanov, Lyudmila Ulitskaya, and a collection of essays by Tatyana Tolstaya. A long-awaited event will also take place in the field of translated literature: ABC will republish Thomas Pynchon's Gravity's Rainbow in a new edition.

Due to the printing crisis, the release of many planned books is significantly delayed, so only approximate release dates for new books are indicated: the publishers ask for possible delays with understanding. Several books have been moved from our last year's review for this year: they are Crawling to Be Born Again in Bethlehem by Joan Didion ( No Kidding Press , scheduled for release in winter-spring), Books of Jacob by Olga Tokarchuk (Eksmo, we are waiting in July), "Daddy" by Emma Kline ("Phantom", summer-autumn), "The Return of Baron Wenkheim" by Laszlo Krasnahorkai (Corpus, autumn-winter) and "Kremulator" by Sasha Filipenko ("Time", spring-summer).

Also in 2022, we will have several Russian-language books about mental disorders and neuropsychiatric dispensaries (“Alpina. Prose”, “There is a meaning”, “Bumkniga”) - it seems that this topic is gradually coming out of the shadows. Among other trends, I would like to note the growing interest in Croatian literature: No Age will release two novels by Ante Tomić, and Ivan Limbach Publishing House will publish Ruth Tannenbaum by Milenko Ergovich.

And the favorites selected by the literary reviewer Elena Vasilyeva and the editor-in-chief of "Reading" Polina Boyarkina, look below.

Edited by Elena Shubina

• Vera Bogdanova "Season of poisoned fruits", March

Vera Bogdanova wrote a novel about a generation in their thirties who are afraid to live their own lives. Zhenya was taught to be good, but she did not live up to expectations. Dasha "doesn't know how to choose men." Ilya is afraid of not being masculine enough. Each of the heroes has their own problems, and the world does not care about people - it explodes and burns every day.

• Sergey Lebedenko “(not) freedom”, April

The debut novel by Sergey Lebedenko, a telegram blogger, curator of the "Experiences" section and columnist of "Reading", is dedicated to power in modern Russia. The fates of the characters will be united by a "theatrical" case, and everyone will be powerless before the indifference of the state machine: defendants, lawyers and even judges.

• Anastasia Sopikova "Longing for the outskirts", spring-summer

The collection of stories by Anastasia Sopikova, the columnist for Reading, cannot be called bright and soul-saving — and it has the honest “Tosca” in its title. The central text of the book "Friend Jonathan" was published in the magazine "Youth" and entered the long list of awards for young authors of FICKN35.

• Alexey Salnikov Occulttrager, August-September

According to Aleksey Salnikov, his new novel will be about “everyday adventures of the occult trader Praskovya Golovnyakova, her few friends and her homunculus. Conditional Pervouralsk, the merged finale of the Game of Thrones, several deaths of the main character, but in the end everything is fine.

• Anastasia Volodina "Protagonist", autumn

The second novel by Lyceum Prize finalist Anastasia Volodina tells about the tragedy that happened at the university. One of the students commits suicide, and his friends and teachers are tormented by the question of why he did it. There are nine chapters and nine voices in the story, each of which adds new details to an already known picture.

• Olga Breininger "Too far", the second half of the year

Olga Breininger, writer and literary anthropologist, author of the novel There Was No Adderall in the Soviet Union, is preparing to present her second major text. According to her, "Too Far" is a novel about social networks, virtual reality and digital copies of ourselves that we create to avoid loneliness.

• Mikhail Elizarov, new collection of prose, second half of

The first new collection of Elizarov's short texts in the last ten years, as the author himself says, will be based on "varieties of demonic worlds. " The book will also include the "Cubes" cycle, which remains the only one not reprinted in the "Mikhail Elizarov's Reading Room" series.

EKSMO

• Ksenia Burzhskaya "St. John's wort", February

In the center of the new book by Xenia Burzhskaya, the author of the novel "My White" (about the growing up of a girl who has two mothers), there are again family issues. The heroes are trying to build a life on their own illusions and mistakes of the past, on addiction and uncertainty. The word "abuse" has long become understandable and familiar, but is it so easy to distinguish between abuse and passion?

New Literary Review

• Anastasia Vepreva, Roman Osminkin "Kommunalka on Petrogradskaya", February

The phenomenon of the St. Petersburg communal apartment is so curious that it is studied in the literature in different ways - starting from works on sociology and ending with Samokatov's History of the Old Apartment. Another book in the piggy bank of those who are interested is a chronicle of the life of a communal apartment (which miraculously did not disappear) in the post-Soviet era. "A paradoxical artistic fusion of dystopia, literary voyeurism and psychological drama," according to the publishers.

• Per Faxneld “Infernal Feminism: Lucifer as the Liberator of Women in 19th Century Culture” (translated from English by Tatyana Azarkovich), February-March

Per Faxneld, a religious scholar from Stockholm University, has written a book about a new reading of the plot of a woman as the devil's accomplice. In the 19th century, Lucifer began to be considered the liberator of women, an assistant in the fight against patriarchy. This idea is reflected in literature, fine arts and consumer culture items.

• Three books by Elena Dushechkina in the Scientific Library series, the first half of the year

In 2020, Elena Dushechkina, a literary critic and culturologist, a student of Dmitry Likhachev and a professor at St Petersburg University, passed away. The UFO Publishing House will publish her works Strict Joy of Contemplation: Articles on Russian Culture (due in February), Svetlana. Cultural History of the Name" (due to appear in May) and "Russian Tree" (to be released in the autumn).

• Alexandra Arkhipova "An epidemic of rumors in Russia", spring

Alexandra Arkhipova, author of Dangerous Soviet Things, continues to investigate rumors and fakes. She emphasizes that they are distributed by everyone - even educated and experienced people. In a troubled time, it becomes even more difficult to distinguish the reliable from the false - and resisting the infodemic turns out to be no less important than the virus epidemic.

• Alexander Stesin "Troy against all", spring

Known for his travelogues and autobiographical essays, Alexander Stesin, winner of the NOS award for his collection New York Detour, this time has written a novel whose plot hints at autofiction. The main character grows up in Russia, moves to the USA, and then goes to work in Angola. All his life he is in search of something - and he cannot find it in any way.

• Oksana Vasyakina Steppe, spring

One of the main novels of last year, The Wound, was dedicated to the death of her mother, Vasyakina's new novel is about the death of her father. And also about the HIV epidemic and how our country cannot cope with its history, how people who witnessed and participated in historical events continue to live in them. “The Wound was cold, but the Steppe will be warm,” says the writer herself.

Limbus Press

• Dmitry Bakin "Pursued by life", winter

Dmitry Bakin, who died in 2015, is called one of the most extraordinary and mysterious writers of post-perestroika Russia, little known to a wide audience. During his lifetime, he actively published in literary magazines and gained loyal admirers, his book "Country of Origin" in 1996 received "Anti-Booker". Driven by Life is the most complete collection of his works.

• Sofia Sinitskaya Chronicle of Hunchbacked, winter-spring

The main storyteller of modern Russian literature, Sofia Sinitskaya, places the city at the center of her new novel - but no, not St. Petersburg, but Vyborg, from the time it was founded by the Swedes to the present day. And, of course, she does everything for which we love her: she creates a fascinating historical saga in which real events are intertwined with fantasy ones, documentaries with mythology, eventually turning the text into phantasmagoric chronicles.

• Alla Gorbunova "Kukushkin honey", winter-spring

After the triumph of the collection of short stories "The End of the World, My Love", the poetess Alla Gorbunova published two more books of prose, but poetry will be published for the first time after a long break. Kukushkin Honey will include texts written over the past three years. The title is a symbol of the impossible: it is a combination of the "honey of poetry" from Scandinavian mythology and the "cuckoo's nest" from the English counting rhyme.

• Native Speech: From Archpriest Avvakum to the Leningrad Group (compiled by Andrey Rossomahin), spring-summer

"Native speech" is an international scientific collection, articles for which were written by two dozen scientists - representatives of various academic disciplines. The texts of the anthology are devoted to the origin of obscene words, their existence in folklore, their therapeutic effect and political pragmatics, as well as their use in the songs of the Leningrad group.

• "Odyssey" in the retelling of Sergei Nosov, summer

"Limbus Press" continues the "Epos" series, for which modern writers retell the heroic songs of different peoples. This time - the great about the great: Sergei Nosov will rewrite Homer's "Odyssey" in his own way, for him this legend is "something from childhood. "

Ivan Limbach Publishing House

• Dominique Fortier Cities on Paper. Life of Emily Dickinson (translated from French by Alla Smirnova), winter

Canadian writer Dominique Fortier created a literary portrait of the American poet Emily Dickinson, in which she explores the nature of creativity in general — as a journey into oneself. Dickinson herself was ahead of the time in which she lived, she was able to recreate the whole world in a few poetic lines without leaving her garden or even her room.

• Alexander Sobolev "Shadow over the right shoulder", spring

The author's new novel "Gryphons guard the lyre": an old manuscript was found in an antique shop in Vienna, authored by an unknown person who lived in 1916 in the Vologda province. He finds himself involved in a series of disturbing and mysterious phenomena that lead to new interpretations of eternal questions - about the blindness of passion, about guilt and responsibility, about the importunity of kindness and the cruelty of love of freedom.

ALPINA.PROZA

• Alexey Polyarinov Night Shift, March

"Night Shift" - a collection of articles, essays and essays by the writer Alexei Polyarinov. This book can be called a kind of continuation of "Almost Two Kilograms of Words", a hit three years ago: at that time, Polarinov spoke about literature and cinema in such a fascinating way that all the texts and films discussed in the book gained new admirers.

• Rahim Jafarov "His last days", summer

In 2021, Rahim Jafarov won the New Horizons Award with his novel Sato. In the new novel His Last Days, the hero-writer imitates a mental disorder in order to end up in a psychiatric hospital and describe this experience in a book whose character, surprise, also writes about a person with a deviation.

• Islam Khanipaev "Cold Eyes", August

Last year, the director and screenwriter from Dagestan, Islam Khanipaev, took second place in the Prose category of the Lyceum Prize for Young Authors with the story Type Me, the story of an eight-year-old boy who is being bullied at school. Then the manuscript was shortlisted for the NOS award. "Cold Eyes" is a new work by Khanipaev - an action-packed psychological detective novel.

CORPUS

• Vladimir Nabokov "Hell, or Joy" (translated from English by Andrey Babikov), April

The publishing house Corpus continues a large-scale project to republish texts by Vladimir Nabokov. The writer's longest and most complex novel, Ada, has not only been republished, but also retranslated by Andrey Babikov, editor of the Nabokov series. An alternate history set in Anti-Terra contains another novel in the same genre, and Nabokov is once again as modern as ever.

• Jonathan Franzen "Crossroads" (translated from English by Yulia Poleshchuk), spring

A new novel from the author of "Amendments", "Freedom" and "Sinlessness". On Christmas Eve 1971, each member of the Hildebrandt family finds themselves at a crossroads. Parents, the priest and his wife, and their children face problems related to religion, sex, self-determination. As always, Franzen creates a variant of the great American novel.

Phantom Press

• John Bart Creative Vacation (translated from English by Maxim Nemtsov), summer-autumn

A novel by a classic of American postmodernism, not previously translated into Russian, based on the real story of the death of former CIA agent John Paisley in 1978. A captivating family saga and love story written using postmodern philological tools.

AZBUKA

• Nina Prowse "Maid" (translated from English by Irina Teterina), January

Maid Molly Gray loves detective stories so much that she decides to investigate the murder of the owner of the hotel where she works. However, she also becomes the main suspect in the crime. The debut novel by Canadian writer Nina Prowse sounded loud even before its release: the rights to film adaptation and translation into thirty-three languages ​​have already been sold.

SINDBAD

• Denis Johnson "Dreams of trains" (translated from English by Sergei Kumysh), spring

The second book translated into Russian by Denis Johnson, a classic of modern American literature. The story "Dreams of Trains" tells about the hermit Robert Grainier, whose life was spent among the hills, rivers and railroad tracks of Northern Idaho. As always with Johnson, this is a text about sadness, light and beauty.

• Sally Rooney "Beautiful world, where are you" (translated from English by Anna Babyashkina), summer

The third novel by Sally Rooney, author of Conversations with Friends and Normal People, was released in English in September 2021 and predictably became a bestseller. The heroes of "Beautiful World" believe that the collapse of humanity is already close, art has become a commodity, and beauty is dead - but they are looking for a way to believe that everything is still not so bad.

NO AGE

• Yoko Ogawa "Professor's Favorite Equation" (translated from Japanese by Dmitry Kovalenin), February

Another novel about memory from the author of The Memory Police. The hero, a mathematician, gets into an accident and gets a head injury. Since then, he remembers what happened to him only for eighty minutes - and then unconsciousness begins. We learn about the fate of the professor from the housekeeper, with whose son the scientist becomes very friendly, and she will tell a story about what it means to live in the present.

• Chelsea J. Summers Definitely Hungry (translated from English by Elena Yakovleva), March

A novel about how sexual appetite can literally mix with hunger. Dorothy Daniels is a restaurant critic who tells the story of her life behind bars because she loves to eat not only food but also men. And they must first be killed. April

The description of McKay's book immediately brings to mind "All Who Can Breathe Breath" by Linor Goralik. Victims of a mysterious pandemic are beginning to understand the language of animals: mammals, birds, and even insects. Gradually, these voices drive people crazy. The main character Jean, together with a dingo named Sue, goes in search of her ill son and granddaughter, and she discovers a bizarre world in which a person is even more isolated from other inhabitants of the globe.

LIVEBOOK

• Miika Nousiainen "Reboot" (translated from Finnish by Ivan Prilezhaev), spring

The protagonist Sami is almost forty years old, and he desperately dreams of children - even more than his mother, who is expecting grandchildren. However, Sami has yet to be in a serious relationship, and the girls tell him over and over again that they are "not that close." As a result, he will try to change his life - and readers will receive an intergenerational rom-com.

• Jean Hanff Korelitz "Story" (translated from English by Dmitry Shepelev), summer

At the center of the novel is Jacob Finch Bonner, a once promising young writer. For many years he did not write anything worthy. One day, his student from writing classes brings the beginning of a great novel - and soon dies. Jake decides to own the plot, expecting neither blackmail nor retribution.

NO KIDDING Press

• Annie Ernault The Education of a Girl (translated from French by Maria Krasovitskaya), summer

Last year No Kidding Press translated Erno's text "The Event" about a clandestine abortion, the film adaptation of which won the top prize at the Venice Film Festival. In Bringing Up a Girl, Erno also returns to his youth and reminisces about his first sexual experience, which turned into depression and shame.

SUBSCRIPTION Publications

• Virginia Woolf Nanny Lagton's Curtain (translated from English by Shasha Martynova, illustrations by Ivan Sergeev), March

B 19In the year 24, Ann Stephen, the daughter of Virginia's brother, visited the Wolfe house. The writer was finishing her fourth novel, Mrs. Dalloway, but digressed to entertain her niece. So she composed this short fairy tale about an embroidering nanny, the bright land of her dreams, and the enterprising inhabitants. Forty years later, a manuscript of this story was discovered in the archives of the British Museum.

• Lorrie Moore Gate on the Stairs0008

Tessie, a farmer's daughter from the Midwest, goes to university, and after the first semester begins to work as a nanny. She becomes more and more involved in the life of this family, moving away from her own. Critics say that this is not only a novel about the brutality of growing up and indifference, but also about the anxiety and division of America after 9/11.

Ad Marginem

• Rachel Kask "Transit", Kudos (translated from English by Anastasia Basova), winter

The second and third parts of the autofiction trilogy by the British writer Rachel Cask, in which she develops the themes of creativity and life of a creative person, raised in "Contour". In "Transit" the heroine is on the verge of change and wants to live and escape from life at the same time, and in Kudos she is looking for where the border between personality and image lies.

• Olivia Lang Everyone's Body (translated from English by Svetlana Kuznetsova), summer

Everyone's Body is Olivia Lange's latest book to date. The author positions it as a novel about the body and freedom, about sexual violence, about racism and the fight for civil rights. The heroes of a new study by the British writer this time are Nina Simone, Christopher Isherwood, Andrea Dworkin, Sigmund Freud, Susan Sontag and Malcolm H.

• Amy Liptrot The Instant (title in progress; translated from English by Anastasia Basova), summer-autumn

The action of The Instant begins when the action of the book Pasture, the hit eco-fiction of last year, ends. The heroine leaves the Orkney Islands and goes to Berlin. There, she learns about life in a new city, looks for dates on dating apps, and walks in parks and nightclubs. After the themes of ecology and addiction, Liptrop is fascinated by the search for love in the digital age.

THERE IS MEANING

• Henry Mance How to Love Animals in a Man-Created World (translated from English by Vasily Gorokhov), March

We continue the theme of the relationship between people and animals, but in non-fiction. Almost all of us love animals, but does it make their life easier? It seems not much - moreover, it seems that the worst time in the history of their existence has come for them. Journalist Henry Mance proposes ways to end the exploitation of animals in an age of new ethics and humanism.

• Daria Blagova South Wind April

Social journalist Daria Blagova wrote a novel about the integration of patients with mental diagnoses. The main character Sasha, after the death of her mother, returns to her native provincial town in the Caucasus, where her twenty-six-year-old brother Zhenya, who has a mental diagnosis, found himself unattended. Sasha decides to stay in the city and build a new life. April

Following the One Chain anthology, another collection will be released, in which eminent writers will coexist with graduates of the School of Literary Practices. Within the framework of the book, the relationship of modern man with nature will be considered from different points of view, and one of the key problems will be the significance of the place that the world around us occupies in our lives, and the little attention that we pay to it.

MYTH

• Quive McDonnell Strange times. Foreseen Incidents with the Immortals (translated from English by Olga Burdova), January

From the author of the detective The Man with One of the Many Faces is a novel about the work of a weekly supernatural newspaper. One day, journalists have information about a real tragedy at their disposal, and they will have to arrange their own investigation, which can dispel even their skepticism.

• Siran Jay Zhao Iron Widow (translated from English by Evelina Nesimova and Olga Glushkova), March

Zetian lives in a world where people are attacked by alien invaders and many families sell their children to the army. Warriors always fight in combat vehicles in pairs: a man is the main pilot, a woman is the second, and her only task is to die, giving life energy to the first pilot.

• Daniel Handler We are Pirates (translated from English by Sergei Karpov), August

Daniel Handler is better known as Lemony Snicket, but he doesn't just write books for teens. The heroine of We're Pirates, 14-year-old Gwen, hijacks a boat to terrorize San Francisco Bay. Her father will have to go to save his daughter - and so each of the heroes will seek their happiness and freedom.

• Donald Antrim "One Hundred Brothers" (translated from English by Sergey Karpov), August

The One Hundred Brothers was written in 1997, and in 1999 The New Yorker listed Donald Antrim as one of the top twenty writers under the age of forty. The action of "One Hundred Brothers" takes place in one night in the huge library of the family mansion. There are ninety-nine brothers in the house - and the hundredth is missing.

KNIZHNIKI

• Jane Yolen Princess Rosehip (translated from English by Galina Gimon, Olga Bukhina), January

American writer Jane Yolen retells the plot of the fairy tale about Sleeping Beauty, transferring the events to Poland in 1942. It combines a magical story and reality with death camps and guerrillas - and the result is a book about good and evil, hope and despair, and about love.

Popcorn Books

• Evgenia Nekrasova "Skin", winter

The main book series Bookmate Originals 2021 about the American slave Hope and the Russian serf Domna, who change skin and fate and survive in the harsh Russia of the 19th century, is published in paper format. The text has not undergone major changes, but has received a new visual design.

• Ibi Zoboi "Pride" (translated from English by Alexandra Glebovskaya), spring

"Pride and Prejudice" in the Brooklyn setting - this is how the novel by the American writer of Haitian origin Ibi Zoboi can be characterized. She herself grew up in Brooklyn - and the main character of the novel Zuri Benitez lives there, who has Brooklyn and family pride and pride in her Afro-Latino roots.

• Sayaka Murata "Earthnoids" (translated from Japanese by Dmitry Kovalenin), summer

In the latest novel to date, Sayaka Murata, the author of Combini Man, re-creates a heroine who is not like other people. Natsuki grew up in the mountains with her cousin, but circumstances separated them. Now she leads the life of an inconspicuous city dweller, but she is haunted by shadows from her childhood.

• Laurie Holes Anderson Speak Summer

A cult comic written more than twenty years ago and still relevant. Fifteen-year-old Melinda begins to be bullied at school after a party to which she called the police after running away. But she cannot tell anyone what happened then. In 2004, a film adaptation was released, starring Kristen Stewart.

Individuum

• John Higgs Strange and Strange. How Relativity, Rock and Roll and Science Fiction Defined the 20th Century (translated from English by Nikolay Mezin), Spring

Historian and journalist John Higgs offers to look at the 20th century from the point of view of the history of ideas and the gradual penetration of the concept of relativity into all spheres of life. He asks questions: what does science fiction and pop culture have to say about philosophy and psychology? how did scientists and artists, without saying a word, come to the same images? And he is trying to make a forecast of what to expect from the 21st century.

BOOKBOOK

• Alexandra Shevchenko "Stationary", spring

A few years ago, the artist Alexandra Shevchenko ended up in a neuropsychiatric hospital — and after that she created a book about how people with difficult lives live there. The book will feature the voices of Nina, blinded by love for her daughter; Lisa, who hears an obsessive voice; Olya, who voluntarily went into the world of dreams and fantasies; Tanya, who struggles with bipolar affective disorder; Dasha, who suffers from an eating disorder; Svetlana, subject to mania; Artyom with hypersensitivity, as well as the story of Alexandra herself.

RHINO

• Milena Slavitskaya "She" (translated from Czech by Olga Nazarova), February

In the collection of stories by the Czech writer and art historian Milena Slavitskaya, the main characters are secondary female characters from the works of famous writers: Franz Kafka, Samuel Beckett, Henry Miller, Milan Kundera, Thomas Bernhard, Torgni Lindgren and Michel Houellebeck. Another extremely interesting way to re-read the classics.

Text: Elena Vasilyeva Polina Boyarkina

Publication date: January 19, 2022
Category: Remarks

Tags: ABC Bookbook Ivan Limbakh Publishing House UFO novelties Edited by Elena Shubina Sinbad Eksmo No Kidding Press Popcorn Books

Collections:

Quive McDonnell. The Man with One of Many Faces

The protagonist of Detective Quive McDonnell's "The Man with One of Many Faces" is Paul Mulcrone. He has a rather strange job: he comes to the memory-losing clients in nursing homes to portray their relatives. It would seem that things could go wrong. But one day they tried to kill him. And then again - and, obviously, not by chance ...

DiCaprio won't call

The plot of "The Story of a Marriage" is as follows: there lives in the world a housewife, Pearly Cook, a nondescript black woman in her thirties. She lives with her husband Holland and their son, who has polio. They also have a dog. In order not to annoy Holland, the dog does not bark, Perly does not talk, the son walks on tiptoe. We know about Holland that he is amazingly handsome and amazingly vulnerable - that's probably all. And then - a dazzling stranger who offers Purley a lot of money for her faithful.

Ilya Veresov. We other vskl

In the poetic world of Ilya Veresov "weights are transparently dripping from the sky", snow has fallen and "the sky - getting ready to jump - is ringing with bubbles of ulcers". The first “Experiments” this year are on the “Readings” website.

Evgenia Nekrasova: I want to create a community for the protection of mythical creatures

In 2021, the writer Evgenia Nekrasova published the book series Skin and the collection House Love. In December, in St. Petersburg, a presentation of "Domovoi Love" was held, which was held by the editor-in-chief of "Reading" Polina Boyarkina. In continuation of this conversation, and ahead of the release of the paper version of Skin by Popcorn Books, Evgeniya Nekrasova and Polina Boyarkina discussed why the future of Russian literature lies in hybridity, whether it is possible to write a text about another culture without appropriation, and how magical consciousness works. Details are in the new issue of a series of interviews with young authors.

The Newest Literary Review: The Top Books of November and December by Vera Bogdanova

Vera Bogdanova, writer, literary reviewer and author of the Bogdanova and the Times blog, talks about the most interesting novelties in fiction and non-fiction in Russia and the United States - a look at Russian book market in the context of the global literary process. In this issue: new novels by Anna Matveeva and Jodi Picoult, quarantine on a paradise island, medieval sex and uncomfortable women.

Focalin vs Adderall: Differences, Similarities & What's Best for You - Drug Vs. Friend

Home >> Drug Vs. Friend >> Focalin vs Adderall: Differences, Similarities & Which One Is Best for You

Drug Vs. Friend

Drug Overview and Key Differences | Conditions of treatment | Efficiency | Insurance coverage and cost comparison | Side effects | Drug Interactions | Warnings | FAQ

Focaline (dexmethylphenidate) and Adderall (dextroamphetamine/levoamphetamine) are medicines used to treat ADHD or Attention Deficit Hyperactivity Disorder. As stimulants, these drugs help improve concentration and reduce impulsivity in people with ADHD. Although their exact mode of action is unknown, Focalin and Adderall are thought to increase the effects of norepinephrine and dopamine on the brain. Low levels of norepinephrine and dopamine can contribute to the development of ADHD symptoms.

Focalin and Adderall are in the same class of drugs. However, they do have some differences in formulation, usage, and side effects.

What are the main differences between Focalin and Adderall?

Focalin (Focalin coupons), also known by the generic name dexmethylphenidate, is manufactured by Novartis Pharmaceuticals. It is an isomer or close relative of methylphenidate, the active ingredient in Ritalin, concerto, metadata, and daitran. As an isomer, it is expected to be more potent than preparations containing methylphenidate.

Focalin (more about Focalin) is available as immediate release tablets in 2.5 mg, 5 mg or 10 mg doses. Focalin is rapidly absorbed after administration and reaches its maximum concentration in the blood after 1–1.5 hours. It is usually taken twice a day and lasts about four hours per dose.

Focalin XR is an extended release tablet available in 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, 30 mg, 35 mg and 40 mg doses. Focalin XR can be taken once a day. Due to its long duration, the effects of Focalin XR do not wear off as quickly as Focalin.

Adderall (Adderall Coupons) is a branded ADHD medication manufactured by TEVA Pharmaceuticals. It contains dextroamphetamine and levoamphetamine combined with four different amphetamine salts.

Adderall (more about Addreall) is available in 5mg, 7.5mg, 10mg, 12.5mg, 15mg, 20mg and 30mg immediate release tablets. Adderall reaches its maximum concentration approximately three hours after ingestion, with the effect typically lasting four to six hours.

Adderall XR is an extended release formulation of Adderall that is available in 5 mg, 10 mg, 15 mg, 20 mg, 25 mg and 30 mg dosages. Adderall Extended Release is administered once a day and its effect lasts up to 12 hours. Unlike Focalin, those with kidney problems may need to adjust their Adderall dosage. Adderall can accumulate in the body when the kidneys are damaged and increase the risk of side effects.

Main differences between Focalin and Adderall
What form(s) does the drug come in?	Oral tablet	Oral tablet
What is the standard dosage?	Initially 2.5 mg twice daily. Doses should be taken at intervals of 4 hours, regardless of meals. Doses may be increased by 2.5–5 mg up to a maximum amount of 20 mg/day or 10 mg twice daily.	Children 3 to 5 years: 2.5 mg daily. The dosage can be increased by 2.5 mg at weekly intervals. Adults and children 6 years of age and older: 5 mg once or twice a day. The dosage can be increased by 5 mg at weekly intervals.
How long does a typical treatment take?	Long-term use should be evaluated periodically.	Long-term use should be evaluated periodically.
Who usually takes this medicine?	Adults and children 6 years and older	Adults and children 3 years and older

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Conditions treated by Focalin and Adderall

Focalin and Adderall are stimulant drugs used to treat ADHD. Both drugs treat ADHD symptoms such as impulsivity, anxiety, and problems with organization, time management, and multitasking.

Focalin is used to treat ADHD in adults and children 6 years of age and older, while Adderall may be used to treat ADHD in adults and children 3 years of age and older. The contents of Focalin XR and Adderall XR capsules can be added to applesauce for easier intake in children with ADHD.

Adderall is also FDA approved for the treatment of narcolepsy, a chronic condition associated with excessive daytime sleepiness. Focalin is not approved for the treatment of narcolepsy, although it can be used off-label as a stimulant.

One systematic review in The Lancet pooled data from 133 double-blind, randomized clinical trials. This review compared preparations containing methylphenidate, amphetamines, and non-stimulants such as guanfacine and clonidine. The results showed that preparations containing methylphenidate are more effective in children and adolescents, while amphetamines are more effective in adults. Amphetamines such as Adderall (dextroamphetamine/levoamphetamine) and Vyvans (lisdexamphetamine) are also preferred as first-line short-term treatments for ADHD.

Talk to your doctor about the best ADHD treatment for you or your child. One treatment may be preferred over another depending on age, previously tried medications, and general condition.

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Focalin and Adderall coverage and cost comparison

Many Medicare and insurance programs cover Generic Focalin. With an average price of around $110, the Focalin can be quite expensive without insurance. You can use the Focalin SingleCare card to save more. For a 30-day supply of 10mg tablets, the SingleCare discount can bring the cost down to under $40 depending on which pharmacy you use.

Get a discount card with a SingleCare prescription

Generic Adderall may be covered by some Medicare plans and insurance. Without insurance, Adderall can cost an average of $132. However, you don't have to pay more than you need to for ADHD treatment. Using an Adderall discount card can bring the price down to around $28 at participating pharmacies.

9000 9000 Medepa0008

	Focalin	Adderall
Usually covered?	yes	yes
Usually covered by Medicare Part D?	Yes	Yes
Standard dosage	10 mg twice a day (60 tablets)	10 mg once a day
0–36 US dollars	7–78 dollars
Cost SingleCare	$ 37 +	27+ 27+ 27+ 27+ 27+ 27+

9059 9 Adderall

The most common side effects of Focalin and Adderall are indigestion (abdominal pain), palpitations (palpitations), increased blood pressure, nausea, and dry mouth. Stimulants can also cause loss of appetite, which can lead to weight loss.

Focalin may also cause other side effects such as sore throat and migraine. Other side effects of Adderall include an unpleasant taste or taste disturbance.

Serious side effects include hypersensitivity reactions or allergic reactions to drug ingredients. Seek medical attention right away if you have a severe rash or difficulty breathing (anaphylaxis) after taking these medicines.

9019 Yes

99

9Applicable?	Frequency	Applicable?	Frequency
Lumber pain	Yes	*	*
LAST

Source: DailyMed (Focalin), DailyMed (Adderall)

Frequency not based on face-to-face trial data. This may not be a complete list of side effects that you may experience. Please contact your doctor or health care provider for more information.

*not reported

Focalin and Adderall drug interactions

Focalin and Adderall have similar drug interactions. Monoamine oxidase inhibitors (MAOIs) may enhance the effects of CNS stimulants such as Focalin and Adderall. Taking MAOIs with CNS stimulants can lead to dangerously high blood pressure (hypertensive crisis), stroke, and heart attack. Do not use Focalin or Adderall with an MAOI or within 14 days of stopping an MAOI.

The use of focaline and adderall should be monitored in individuals taking serotonergic drugs such as antidepressants, fentanyl, lithium and St. John's wort. Combining Focalin or Adderall with serotonergic drugs may increase the risk of serotonin syndrome, a potentially life-threatening condition.

Since stimulants can increase blood pressure, the effects of blood pressure medications may be reduced. If you are taking stimulants and blood pressure medications, your dosage may need to be adjusted.

Warnings Focalin and Adderall

Focalin and Adderall are controlled substances that are potentially dangerous to abuse. Both drugs are classified as DEA Schedule II drugs. Taking these medicines for a long time can increase the risk of abuse and dependence, especially if they are taken beyond the prescribed dosage. These medicines should only be used under the direction of a doctor.

Focalin and Adderall are CNS stimulants that may be associated with an increased risk of cardiovascular events such as stroke and heart attacks. Their use should be supervised by those with a history of heart disease and heart rhythm problems (arrhythmias). Stimulants can also increase blood pressure and heart rate. Monitor your blood pressure while taking stimulants, especially if you have a history of high blood pressure.

The use of stimulants may cause or exacerbate other mental health problems. Watch for signs of hostility, anxiety, aggression, paranoia, and depression while taking stimulants. Tell your doctor if you have a history of depression or bipolar disorder before taking Focalin or Adderall.

Frequently Asked Questions about Focalin vs. Adderall

What is focaline?

Focalin is a prescription drug for ADHD. It is available as a generic medicine called dexmethylphenidate. Focalin is part of a class of drugs called CNS stimulants. Focalin immediate release tablets are usually taken twice a day with effects lasting up to four hours between doses. Focalin is also available in extended release tablets.

What is Adderall?

Adderall is a brand-name ADHD medication also available as a generic drug containing a combination of amphetamine salts. It acts as a stimulant drug to improve attention and control impulsivity in people with ADHD. Adderall is available in both immediate release and extended release forms. Adderall immediate release tablets are usually taken every four to six hours for ADHD.

Are Focalin and Adderall the same thing?

Both Focalin and Adderall act in a similar way by blocking the reuptake of norepinephrine and dopamine in the brain. However, Focalin contains dexmethylphenidate and Adderall contains amphetamine salts. They also have some differences in available strengths and side effects.

Which is better - Focalin or Adderall?

Both Focalin and Adderall are effective treatment options for ADHD. Research suggests that Focalin is better for treating children and adolescents, while Adderall is better for treating adults with ADHD. Both formulations are available in immediate and extended release versions. Consult with your healthcare provider to determine the best treatment option for you.

Can I use Focalin or Adderall while pregnant?

There may be a risk of birth defects when using Focalin or Adderall during pregnancy. Stimulants should only be used if the benefits outweigh the potential risks. Not enough information is known about the risk of side effects when taking stimulants during pregnancy. Check with your doctor before using Focalin or Adderall during pregnancy.

Can I take Focalin or Adderall with alcohol?

It is generally not recommended to drink alcohol while taking Focalin or Adderall. Drinking alcohol while taking stimulants can increase the risk of side effects, especially heart problems. The combination of alcohol and stimulants can also increase the risk of abuse, addiction, and overdose.

How strong is Focalin compared to Adderall?

Focalin and Adderall are comparable in efficacy in the treatment of ADHD. The effectiveness of the stimulant depends on the dosage prescribed, other medications you may be taking, and your general condition.

What is the equivalent of Adderall?

Adderall is a stimulant medication that contains a combination of amphetamine salts. Other short-acting stimulant drugs that treat ADHD include:

• Focalin (dexmethylphenidate)
• Ritalin (methylphenidate)
• Dexedrine (dextroamphetamine)

Focalin keeps you awake? / Is Focalin a stimulant?

Focalin is a CNS stimulant. Focalin may be prescribed to improve attention and focus in people with ADHD. Due to its stimulating effect, it can also promote wakefulness. However, it is not approved by the FDA for the treatment of sleep disorders such as narcolepsy.

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