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With Training, People in Mind-Controlled Wheelchairs Can Navigate Normal, Cluttered Spaces

Nov. 18, 2022 — A mind-controlled wheelchair can help a paralyzed person gain new mobility by translating users' thoughts into mechanical commands. Researchers now demonstrate that tetraplegic users can operate ...


Researchers Identify Protein That Contributes to Tau Neurotoxicity in Alzheimer's Disease

Nov. 17, 2022 — Researchers have identified a protein that interacts and enhances the spread of neurotoxic species of tau -- which is primarily found in neurons that appear abnormal in the brains of Alzheimer's ...


Mental Health, Substance Use Issues Prevalent Among Nonpsychiatric Emergency Room Patients

Nov. 17, 2022 — A new study found that about 45 percent of patients who visit the emergency department for physical injuries and ailments also have mental health and substance use problems that are often ...


New Target for Alzheimer's Therapies Found

Nov. 17, 2022 — Researchers discover link between the protein medin and Alzheimer's ...


Study Yields Clues to Why Alzheimer's Disease Damages Certain Parts of the Brain

Nov. 16, 2022 — A study yields clues to why certain parts of the brain are particularly vulnerable to Alzheimer's damage. It comes down to the gene APOE, the greatest genetic risk factor for Alzheimer's ...


Pattern of Gene Activity for ADHD

Nov. 16, 2022 — Researchers have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD). The study found that individuals diagnosed with ...


Corporal Punishment Affects Brain Activity, Anxiety, and Depression

Nov. 16, 2022 — Don't spank your kids. That's the conventional wisdom that has emerged from decades of research linking corporal punishment to a decline in adolescent health and negative effects on ...


Alzheimer's Risk Gene Undermines Insulation of Brain's 'Wiring'

Nov. 16, 2022 — In people carrying the APOE4 risk variant, a key brain cell type mismanages cholesterol needed to insulate neurons properly --another sign that APOE4 contributes to disease by disrupting lipids in ...


Gossypetin Found in Hibiscus May Beat Alzheimer's Disease

Nov. 16, 2022 — A research team has verified that gossypetin activates immune cells in the brain that clear A beta, which triggers Alzheimer's ...


How Hormonal Birth Control May Affect the Adolescent Brain

Nov. 15, 2022 — One aspect of hormonal contraceptives' effect on the teenage body remains a mystery -- whether and how they modify the developing brain. New research in young rats links synthetic hormones found ...


Potential New Lead Compounds for the Treatment of Depression and Anxiety Disorders

Nov. 15, 2022 — Currently, various classes of drugs are available for the treatment of mental illnesses -- such as depression and anxiety disorders. However, although these drugs confer benefits, they are also . ..


In Utero Exposure to Flame Retardants Increases Anxiety Symptoms in Adolescents

Nov. 15, 2022 — New research found that in utero exposure to certain flame retardant chemicals may be a risk factor for developing anxiety symptoms in early ...


Children Learn More Quickly Than Adults

Nov. 15, 2022 — If you've ever had the feeling that your elementary school kids were 'smarter' than you -- or at least capable of picking up new information and skills faster -- a new study suggests ...


The Hunt for Disrupted Brain Signals Behind Autism

Nov. 15, 2022 — Part of understanding the underlying causes of autism spectrum disorder relies on figuring out which cells' signaling patterns in the brain are disrupted, and when during nervous system ...


Brain Area Thought to Impart Consciousness, Behaves Instead Like an Internet Router

Nov. 14, 2022 — The legendary scientist Francis Crick first postulated in 2005 that the brain region known as the claustrum is the seat of consciousness. Researchers now posit that Crick may have been incorrect: ...


How COVID-19 Causes Neurological Damage

Nov. 14, 2022 — It's not uncommon for people to lose their sense of taste and smell due to a COVID-19 infection. In others, the disease has had an even stronger impact on the nervous system, with effects ...


Fluorescent Mouse Blood Will Help Us Gain Knowledge About Brain Diseases

Nov. 14, 2022 — A fluorescent protein makes it possible to follow disease progression in brain diseases such as Alzheimer's, strokes, and depression. That may lead to better insight into diseases and possible ...


Rats Bop to the Beat

Nov. 11, 2022 — Accurately moving to a musical beat was thought to be a skill innately unique to humans. However, new research now shows that rats also have this ability. The optimal tempo for nodding along was ...


Previously Unknown Ability of the Autonomic Nervous System Discovered

Nov. 11, 2022 — The autonomic nervous system is known as the control center for involuntary bodily processes such as the beating of our hearts and our breathing. The fact that this part of the nervous system also ...


The Nose-Brain Pathway: Exploring the Role of Trigeminal Nerves in Delivering Intranasally Administered Antidepressant

Nov. 11, 2022 — Scientists have developed a novel concept of a nose-to-brain system for the clinical application of neuropeptides. They developed a derivative of glucagon-like peptide-2 and found that when ...


Novel genetically based impulsivity score may help identify children who are especially vulnerable -- ScienceDaily

While not all impulsive behaviour speaks of mental illness, a wide range of mental health disorders which often emerge in adolescence, including depression and substance abuse, have been linked to impulsivity. So, finding a way to identify and treat those who may be particularly vulnerable to impulsivity early in life is especially important.

A group of researchers, led by scholars at McGill University, have developed a genetically based score which could help identify, with a high degree of accuracy (greater than that of any impulsivity scores currently in use), the young children who are most at risk of impulsive behaviour.

Their findings are especially compelling because the score they have developed was able to detect those at a higher risk of impulsivity within three ethnically diverse community samples of children, from a cohort of close to 6,000 children.

This discovery of a novel score for impulsivity in early life can inform prevention strategies and programs for children and adolescents who are at risk for psychiatric disorders. In addition, by describing the function of the gene networks comprising the score, the study can stimulate the development of new therapies in the future.

A shift in perspective leads to new findings

The impulsivity risk score was developed by looking at the co-expression of a number of genes in the prefrontal cortex and the striatum, areas of the brain that play a role in decision-making and emotional regulation, among other things.

"Typically, genetic approaches to identifying the neurobiological signature for impulsivity (or any other condition or disease) tend to focus on identifying the variation in a few genetic markers that might be responsible for the problem," said Patricia Pelufo Silveira, an Associate Professor in the Department of Psychiatry and Researcher at the Douglas Research Centre and one of the two senior authors on the recent paper in Molecular Psychiatry. "We came at the problem from the opposite direction, by focusing on a gene known to be associated with the maturation of the brain in these two key areas and then looking for a network of other genes that were most closely associated with it."

It took a lot of hunting

This approach was based on earlier work in mice models, led by Cecilia Flores, a co-senior author on the paper and a Full Professor, in the Department of Psychiatry which had identified the importance of a specific gene (known as DCC), which acts as a "guidance cue" that determines when and precisely where brain dopamine cells form connections in the prefrontal cortex and striatum. This coordinated development is essential for the maturation of impulse control.

But to create the new impulsivity score, it took a lot of hunting to narrow down the genes most closely associated with DCC. "Our approach exploits the fact that genes operate within complex networks that, ultimately, perform very precise biological functions. These so-called gene networks have the property of being highly tissue-specific, so we began with an unbiased look at groups of genes that are co-expressed with DCC in brain regions known to play an important role supporting inhibitory control," says co-author Jose Maria Restrepo, a PhD student in the Integrated Program in Neuroscience at McGill University.

"The results underline the importance of data sharing and open science," adds Flores. "Imagine if we had had to collect this information in all these countries over all these years. Our discovery was only possible because we had access to all these data."

Story Source:

Materials provided by McGill University. Note: Content may be edited for style and length.

psychology: news today

Power November 14, 2022 18:07

A new law on psychological assistance will help protect Russians from charlatans

Now there are many specialists in the field of psychology working in Russia, but without a legal framework, their competence remains in question.

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Society 04 October 2022 18:02

“We need to live on”: psychologist Zashchirinskaya said that she would help to defeat stress forever

Full immersion in current goals and tasks at work will help to distract from daily negative obsessive thoughts, the expert explained.

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Society September 23, 2022 16:54

Fragile co-dependency: the reasons for the increase in the number of marriages and divorces in St.
Petersburg are named

In St. Petersburg during the two months of the summer the number of separated and formed married couples increased. Psychologist Olga Ivanova explained that this trend is due to the reluctance of young families to work on relationships.

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Incidents September 14, 2022 10:24

A sixth-grader fell from the seventh floor in Tikhvin

The issue of the criminal case is currently being resolved.

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Showbiz 04 September 2022 15:09

Psychologist Stepanova explained why Nagiyev hides his women

Many admirers of Nagiyev would like to get a minute of fame: give out sensational interviews, appear at social events, the specialist is convinced.

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Society 02 September 2022 00:57

The bill on psychological assistance will protect Russians from false specialists

During the coronavirus pandemic, Russians began to turn to psychologists more often. This has led to an increase in the number of scammers who, under the guise of psychological assistance, provide other services.

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Society August 23, 2022 21:16

Petersburg sexologist Frantov forbade kissing a child on the lips

Kissing as a universal form of expressing feelings can become a behavior outside the family, which is not good for the child.

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Society 10 August 2022 14:43

“There is only one strategy”: how to help a child survive the trauma after an encounter with a rapist

A scandalous story happened on Leninsky Prospekt - in the cabin of a trolleybus, a 17-year-old girl was harassed by an unknown person. The attacker faces a criminal article, and the victim - a psychological trauma.

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Society 08 August 2022 14:13

Psychologists told how to save nerves in the absence of a summer vacation

The reaction of the body at critical moments depends entirely on several factors, such as life experience and mental characteristics, experts say.

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Society 05 June 2022 19:18

Psychologist Naumova spoke about the alarming signs of adultery

In order not to bring the relationship to the point of no return and complete collapse, the doctor recommended more often to discuss together points of view even on the simplest everyday problem.

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