Does prozac help with anger

[Anger outbursts in unipolar depressive disorders]

Review

. 1997 Jun;23 Spec No 3:39-42.

[Article in French]

M Fava¹

Affiliations

Affiliation

¹ Massachusetts General Hospital, Boston 02114, USA.

PMID: 9333559

Review

[Article in French]

M Fava. Encephale. 1997 Jun.

. 1997 Jun;23 Spec No 3:39-42.

Author

M Fava¹

Affiliation

¹ Massachusetts General Hospital, Boston 02114, USA.

PMID: 9333559

Abstract

Approximately one third of depressed outpatients present with "anger attacks", sudden spells of anger accompanied by symptoms of autonomic activation such as tachycardia, sweating, flushing, and tightness of the chest. These anger attacks are experienced by the patients as uncharacteristic of them and inappropriate to the situations in which they occur. Depressed patients with anger attacks are significantly more anxious and hostile, and they are more likely to meet criteria for borderline, histrionic, narcissistic, and antisocial personality disorders than depressed patients without anger attacks. Treatment studies suggest that antidepressant treatment of anger attacks in depression is helpful and sage. Anger attacks disappear in 53-71% of depressed outpatients treated with antidepressants such as fluoxetine (Prozac), sertraline and imipramine. In addition, the rate of emergence of anger attacks after treatment with fluoxetine (Prozac) (6-7%) is no different from the rates observed after treatment with sertraline (8%) and imipramine (10%), and lower than the rate with placebo (20%). Finally, one can hypothesize that antidepressants that affect serotonergic neurotransmission, known to be involved in the modulation of aggressive behavior in animals and humans, should be particularly effective in this population. Larger placebo-controlled studies, comparing selective serotonin reuptake inhibitors such as fluoxetine with relatively noradrenergic tricyclic antidepressants such as desipramine, may help us understand whether depressed patients with anger attacks show a distinctive responsiveness to drug treatment.

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Fluoxetine in the treatment of anger: an open clinical trial

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Clinical Trial

. 1996 Sep;57(9):398-401.

R N Rubey¹, M R Johnson, N Emmanuel, R B Lydiard

Affiliations

Affiliation

¹ Department of Veterans Affairs, Charleston, SC 29401-5799, USA.

PMID: 9746447

Clinical Trial

R N Rubey et al. J Clin Psychiatry. 1996 Sep.

. 1996 Sep;57(9):398-401.

Authors

R N Rubey¹, M R Johnson, N Emmanuel, R B Lydiard

Affiliation

¹ Department of Veterans Affairs, Charleston, SC 29401-5799, USA.

PMID: 9746447

Abstract

Background: Intense anger, easy irritability, and low frustration tolerance are frequently encountered in clinical practice and may occur as part of the constellation of symptoms associated with a number of Axis I and Axis II diagnoses. Recent studies have suggested the efficacy of fluoxetine in treating anger in depressed and borderline patients. The present study examines the treatment of anger as a target symptom regardless of accompanying psychopathology.

Method: In this preliminary trial, 11 subjects experiencing intense anger were treated in an open-label fashion with fluoxetine over an 8-week period. Anger was measured by a clinician-administered Clinical Global Impressions-Severity (CGI-S) scale and a self-report anger inventory, the Multidimensional Anger Inventory (MAI). The Hamilton Rating Scale for Depression was administered at baseline and final visits.

Results: All 11 enrolled patients completed the study, and all patients demonstrated clinical improvement as measured by both the CGI-S and the MAI. Nine patients were rated as responders and 2 as nonresponders according to prospectively established criteria. Fluoxetine was well tolerated and showed rapid onset of action.

Conclusion: This study is limited by small sample size and nonblinded, open-label design, but nonetheless suggests that fluoxetine may be useful in moderating anger as it occurs as part of the symptomatology of a number of Axis I and Axis II disorders. Controlled studies are warranted.

Cited by

Relationship of anger and anger attacks with depression: a brief review.
Painuly N, Sharan P, Mattoo SK. Painuly N, et al. Eur Arch Psychiatry Clin Neurosci. 2005 Aug;255(4):215-22. doi: 10.1007/s00406-004-0539-5. Epub 2004 Nov 12. Eur Arch Psychiatry Clin Neurosci. 2005. PMID: 16133740 Review.

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90,000 Feelings Blocked by Antidepressants - T&P

Psychiatrist Judy Holland told The New York Times how social and drug-industry behaviors force women to suppress their natural emotionality with the help of antidepressants.

Emotions are normal, but pills make feelings synthetic, says Holland. T&P translated the most important thing from her speech.

Women are sensitive. They have evolved to be more sensitive to their environment, more empathic for the needs of their children, and more intuition for the intentions of their partners. Some research suggests that women are better at articulating their feelings because, over the course of their development, their brains have learned to spend more effort on speech, memory, and the perception of other people's emotions.

These observations are based in biology, not feminist or anti-feminist ideologies, but have social causes. Women's sensitivity is a sign of health, not disease. This is the source of strength. But women are under constant pressure to control their emotions. They are taught to apologize for their tears, to restrain their anger and be afraid to appear hysterical.

Women are almost twice as likely as men to be diagnosed with depression and anxiety. Drugs help many of them, but for others they do a disservice. The increase in prescriptions for psychiatric drugs, especially those prescribed by doctors from third-party specialties, is creating a new norm of behavior, pushing women to seek medication support.

The chemistry of the brain and body must be in harmony. Imagine that serotonin is responsible for positive thinking in the brain. Too high content of this hormone guarantees carelessness, too low - makes you see a problem in every situation.

Tears are not necessarily associated with sadness. When we are frightened, confused, when we face injustice or are deeply moved by events around us, we cry. This does not mean weakness or loss of control.

Most antidepressants used to treat anxiety increase the production of serotonin. It seems that things are getting better, but this is far from always beneficial. Serotonin can not only drive away fears, but also cause emotional and physical numbness. As a rule, it suppresses negative emotions more than positive ones, makes a person feel more rational and dispassionate. But in some cases, antidepressants drown out many other human feelings: empathy, irritation, sadness, creativity, anger, mourning, anxiety, erotic desire.

Tears are not necessarily associated with sadness. When we are frightened, confused, when we face injustice or are deeply moved by events around us, we cry. This does not mean weakness or loss of control. With high doses of antidepressants, it becomes very difficult to cry. As a result, a person may be in the grip of apathy and indifference. The need for change manifests itself through a feeling of discomfort and anxiety due to the fact that something is going wrong - we understand what is right only when we can feel it. If the cure is to increase complacency, it won't help anyone.

From an excess of medicines, human emotions become synthetic. For personal growth, happier relationships, and a more peaceful world, we need more empathy, compassion, responsiveness, emotionality, and sensitivity, not the other way around.

For more information on the blockade of female sensitivity from taking antidepressants, visit The New York Times website.

Alexey Pavperov

how to be happy and not get drunk

Fluoxetine is known in the drug market as Prozac. This antidepressant is not the first decade of confident steps spread around the world. Allegedly, you can take a completely legal pill and become happier, get rid of fears or embarrassment, worry less about trifles and be more efficient. Some even drink a miracle pill in order to lose weight.

In Russia, you need a prescription to buy medicine. But sales are brisk and without much control. However, as the “happiness pill” spreads across the vast expanses of the largest country, a significant part of the population of which lives in the middle lane with a short summer and, for many, a completely vile autumn, opponents and critics appear at the remedy for all ailments. A new wave of prohibition initiatives may overwhelm Russian society after the investigation of a criminal case related to the use of an antidepressant by children is over.

At the end of autumn 2013, in one of the Family Doctor clinics, the attending physician prescribed fluoxetine for a minor patient. On January 2 of the following year, the girl committed suicide.

Now all the circumstances of what happened are being clarified. According to Storm, a criminal case was initiated under Article 238 of the Criminal Code of the Russian Federation “Production, storage, transportation or sale of goods and products, performance of work or provision of services that do not meet safety requirements” (which negligently caused serious harm to health or death of a person). The maximum penalty is imprisonment for up to six years.

Authorities believe that fluoxetine was prescribed to a teenager despite the fact that there are contraindications contained in the instructions, according to which it should not be prescribed to persons under 18 years of age. In addition, in their opinion, there was no conclusion of the medical commission on the prescription of the drug for indications not approved in the instructions for its use.

According to the case file, the girl sustained fatal injuries as a result of a side effect of fluoxetine, an increase in suicidal tendencies.

It is worth noting that the girl made attempts to die before. Now the investigation has to find out all the circumstances of the incident.

Quite simply, fluoxetine causes the body to produce serotonin, which is responsible for the functioning of the brain and the entire nervous system. Those who are clinically depressed have a reduced content of this substance, so such patients are in a depressed state. Stimulation of the production of serotonin leads to the activation of the brain, and what the mental abilities are aimed at - except for the person himself, probably no one will say for sure. From this, the results of the use of fluoxetine may vary.

Read where it is convenient: add Daily Storm to your favorites in Yandex.News, subscribe to Zen or Telegram.

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Zen

More than 40 million people worldwide use Prozac, which is slightly less than the population of Ukraine. The drug is especially popular in its "homeland", in the United States. That's where most of his critics are. They argue that the company that developed the drug deliberately concealed real statistics, including that in minors, taking pills can develop suicidal moods and aggressive behavior. By the way, the inspirers of the Ivanteevsky shooter - the schoolchildren who staged the massacre at the Columbine educational institution - were "sitting" on Prozac.

There is a wealth of analytical material on the Web, of varying quality, about the pros and cons of using Prozac. Their authors convincingly prove their position, and disputes are still going on. Find out how harmful or useful this antidepressant really is, how it affects fragile minds, what percentage of those who took it decided to commit suicide, and what percentage are more successful at work and manage anger, and what does the war of pharmacological giants probably have to do with it? deal with the state, involving experts. In the meantime, Prozac can be bought at the pharmacy.

Interviewed by "Storm" Russian parliamentarians from the profile committees of both chambers did not express a consolidated opinion on the antidepressant that is fashionable in the West. Some - referring to the lack of knowledge about the medicine, and this once again suggests that in Russia the remedy is not yet so common.

Doctor of Medicine, pediatric neurologist Pavel Sokol explained in a commentary to the publication that, in general, fluoxetine is not a children's story, but a doctor who prescribes it to minors takes professional risks. “This means that the use of the drug can be challenged even in criminal proceedings. Moreover, the public was already frightened by the case of child suicide from such drugs. The doctor also stressed that he had no personal experience with the use of fluoxetine in pediatric practice, since it is prohibited for minors.

According to the memoirs of children's suicidologist, psychotherapist Gennady Bannikov, earlier Prozac could be given to children from the age of 14, since the treatment of adolescents from this age is not much different from the treatment of adults.

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Does prozac help with anger

[Anger outbursts in unipolar depressive disorders]

Affiliation

Author

Affiliation

Abstract

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Fluoxetine in the treatment of anger: an open clinical trial

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Create a file for external citation management software

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Psychiatrist Judy Holland told The New York Times how social and drug-industry behaviors force women to suppress their natural emotionality with the help of antidepressants.

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how to be happy and not get drunk