When to take effexor xr

How and when to take venlafaxine

Venlafaxine tablets and capsules can be either standard or slow release.

Standard tablets release the venlafaxine into your system as soon as you swallow them. Slow release tablets and capsules are released into your system gradually.

Dosage and strength

The usual starting dose for venlafaxine is 75mg a day but your doctor may gradually increase it to a maximum dose of 375mg.

If you have problems with your liver or kidneys your doctor might prescribe a lower dose.

Standard tablets come as 37.5mg or 75mg tablets. Slow release tablets and capsules come as 75mg and 150mg.

How to take it

You will usually take standard tablets twice a day, once in the morning and once in the evening.

You will usually take slow release tablets or capsules once a day. You can take them at any time as long as you stick to the same time every day. If you have trouble sleeping, it's best to take it in the morning.

How long to take it for

Once you're feeling better it's likely that you will continue to take venlafaxine for several more months. Most doctors recommend that you take antidepressants for 6 months to 1 year after you no longer feel depressed. Stopping before that time can make depression come back.

The decision to stop your treatment or carry on will depend on what symptoms you have and how serious they are. It will also depend on whether it's a one-off problem or one that keeps coming back, how well venlafaxine works for you, and whether you have had any bad side effects.

If you forget to take it

If you occasionally forget to take a dose, just take your next dose at the usual time. Never take 2 doses at the same time to make up for a forgotten one.

If you often forget doses, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to help you remember to take your medicine.

Stopping venlafaxine

Your doctor will recommend reducing your dose gradually over several weeks, if you have been taking venlafaxine for a long time.

This is to help prevent any withdrawal symptoms you might get as a reaction to coming off the medicine. These include:

feeling dizzy
feeling sick
numbness or tingling in the hands or feet
trouble sleeping
feeling agitated or anxious
headaches
shaking

If you take too much

The amount of venlafaxine that can lead to an overdose varies from person to person.

Taking too much can cause symptoms such as:

feeling sleepy
feeling sick (nausea) or being sick (vomiting)
a faster heartbeat
feeling dizzy
fits or seizures

Urgent advice: Contact 111 for advice now if:

you take more than your prescribed dose of venlafaxine

Go to 111.nhs.uk or call 111.

If you need to go to a A&E, do not drive yourself. Get someone else to drive you or call for an ambulance.

Take the venlafaxine packet, or the leaflet inside it, plus any remaining medicine with you.

Page last reviewed: 10 February 2022
Next review due: 10 February 2025

Effexor XR Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Warnings:

Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits. However, a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. It is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition.

Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.

Warnings:

. .. Show More

Uses

Venlafaxine is used to treat depression, anxiety, panic attacks, and social anxiety disorder (social phobia). It may improve your mood and energy level and may help restore your interest in daily living. It may also decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. Venlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.

How to use Effexor XR

Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start using venlafaxine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually once daily with food, either in the morning or evening.

Do not crush, chew, or dissolve this medication. Doing so can release all of the drug at once, increasing the risk of side effects. Swallow whole without crushing or chewing.

If you are taking the capsules, swallow them whole. If you have trouble swallowing the capsules whole, you may open the capsule and sprinkle the contents onto a spoonful of applesauce. Swallow all of the mixture right away without chewing. Drink a glass of water after each dose.

The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Keep taking this medication even if you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Also, you may experience symptoms such as confusion, mood swings, blurred vision, headache, tiredness, sleep changes, and brief feelings similar to electric shock. Your dose may need to be gradually decreased to reduce side effects. Report any new or worsening symptoms right away.

It may take several weeks to feel the benefit of this medication. Tell your doctor if your condition lasts or gets worse.

Side Effects

Precautions

Before taking venlafaxine, tell your doctor or pharmacist if you are allergic to it; or to desvenlafaxine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, personal or family history of glaucoma (angle-closure type), high blood pressure, heart problems (such as heart failure, previous heart attack), high cholesterol, kidney disease, liver disease, seizure disorder, thyroid disease.

This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially dizziness when standing. Older adults may also be more likely to develop a type of salt imbalance (hyponatremia), especially if they are taking "water pills" (diuretics). Dizziness and salt imbalance can increase the risk of falling. Older adults may also be at greater risk for bleeding while using this drug.

Children may be more sensitive to the side effects of the drug, especially loss of appetite and weight loss. Monitor weight and height in children who are taking this drug.

During pregnancy, this medication should be used only when clearly needed. It may harm an unborn baby. Also, babies born to mothers who have used this drug during the last 3 months of pregnancy may rarely develop withdrawal symptoms such as feeding/breathing difficulties, seizures, muscle stiffness, or constant crying. If you notice any of these symptoms in your newborn, tell the doctor promptly.

Since untreated mental/mood problems (such as depression, anxiety, panic attacks) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss the benefits and risks of using this medication during pregnancy with your doctor.

This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen/naproxen, "blood thinners" such as dabigatran/warfarin).

Aspirin can increase the risk of bleeding when used with this medication. However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually 81-162 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and at least 7 days after treatment with this medication. Ask your doctor when to start or stop taking this medication.

The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/"ecstasy," St. John's wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, other SNRIs such as duloxetine/milnacipran), tryptophan, among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Venlafaxine is very similar to desvenlafaxine. Do not take medications containing desvenlafaxine while using venlafaxine.

This medication may interfere with certain lab tests (including urine tests for amphetamines), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.

Does Effexor XR interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe drowsiness, seizures, fast/irregular heartbeat.

Do not share this medication with others.

Keep all regular medical and psychiatric appointments. Laboratory and/or medical tests (such as blood pressure, cholesterol) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Effexor - Pharmacy in Israel

Description
Delivery within Israel
Delivery to Russia
Delivery to Belarus

Description

Antidepressant from the group of selective serotonin and norepinephrine reuptake inhibitors. Depression is a very serious reason to see a doctor, you should not ignore the problem that has arisen. You will be prescribed an antidepressant that will help you and restore the lost quality of life and the ability to enjoy. Thinking where to buy Effexor? We recommend you our reliable partner, a pharmacy in the center of Tel Aviv. Buying a drug is simple, contact us through the website, we will help you with placing an order and purchasing.

Mechanism of action

The mechanism of the antidepressant action of effexor is to increase the activity of neurotransmitters during the transmission of nerve impulses to the central nervous system.
Venlafaxine and its main metabolite, O-desmethyl venlafaxine, are potent inhibitors of neuronal reuptake of serotonin and norepinephrine and inhibit dopamine reuptake. Single and long-term administration of venlafaxine and EFA reduces β-adrenergic reactions. nine0013

Application protocol

The drug is taken orally, during meals, swallowed whole, washed down with water.
The recommended starting dose is 75 mg/day. If clinically indicated, the dose may be increased to 375 mg/day, but due to the risk of dose-dependent side risks, this should be done only after clinical evaluation by a specialist. Treatment should continue for at least several months.

Efficacy

Effexor has been shown to be effective in the treatment of depressive disorders in clinical studies. There is a pronounced antidepressant effect, with a decrease in signs of emotional lability, irritability, which leads to an improvement in the quality of life and daily activity. nine0013

Indications

Treatment and prevention of recurrence of major depressive episodes
Treatment of generalized anxiety disorder.
Treatment of social anxiety disorder.
Treatment of panic disorder with or without agoraphobia.

Contraindications

hypersensitivity to effexor or any of the components of the preparation
concomitant use with MAO inhibitors
severe renal and/or liver dysfunction
patients under the age of 18
pregnancy or lactation

Side effects

agranulocytosis, aplastic anemia, pancytopenia, neutropenia, thrombocytopenia, increased blood prolactin concentration
anaphylactic reaction
dizziness, asthenia, weakness, insomnia
tachycardia, atrial fibrillation, QT prolongation
irritability, tremor, muscle hypertonicity, paresthesia
increased blood pressure, sedation, fatigue, asthenia, chills
hyperemia of the skin
decreased appetite, nausea, vomiting, taste perversion
decreased libido, erectile dysfunction and/or ejaculation, urinary incontinence, urinary incontinence, anorgasmia, menorrhagia,
visual impairment, mydriasis, balance disorder, tinnitus, vertigo
depersonalization, nightmares, nervousness, suicidal mood, agitation, confusion, mania, delirium. nine0004

Interaction

Effexor is an inhibitor of the cytochrome P450 2D6 isoenzyme and leads to an increase in the concentration of tricyclic antidepressants, carbamazepine, and some atypical antipsychotics. The drug is not used in combination with MAO inhibitors. Simultaneous use with clozapine increases the concentration of effexor, which can lead to the development of side effects. Drinking alcohol should be avoided while taking Effexor.

Storage conditions

Store in a place protected from light at a temperature not exceeding 25°C, out of the reach of children.

Delivery in Israel

Delivery in Israel

Our pharmacy delivers drugs quickly in Tel Aviv and throughout Israel.

The drug is transported in a refrigerator, while maintaining the temperature regime. This allows you not to spoil the medicine.

How can I order delivery of medication?

To place an order for the delivery of medicines in Tel Aviv or Israel, please contact our pharmacist by phone in the "Contacts" section. We will inform you as soon as possible and the shipping cost. nine0013

Delivery to Russia

Delivery is carried out by the Israeli company Bio Logistica LTD, which specializes in the legal transportation of medicines and biological materials.

Registration of customs documents for the delivery of medicines, as well as airport security permits, accompanying documentation.

The logistics company we cooperate with helps with all these questions. nine0013

To find out the cost of delivering medicines to your country and city, contact Bio Logistica LTD directly via WhatsApp and they will advise you free of charge.

WhatsApp +7 999 542 02 88 (Russian speaking manager)

Every Israeli pharmacy offers discounts on certain medicines. Before ordering medicines from Israel, we recommend that you contact our pharmacists to clarify the availability of discounts and special offers.

In this case, you get the opportunity to return VAT included in the price in the amount of 15% at the TAX FREE counter at the airport. Ben Gurion. nine0013

All documents required for the TAXFREE refund are processed at the pharmacy after the purchase.

Please note that VAT refunds do not apply to special offers.

Delivery to Belarus

Delivery is carried out by the Israeli company Bio Logistica LTD, which specializes in the legal transportation of medicines and biological materials.

Registration of customs documents for the delivery of medicines, as well as airport security permits, accompanying documentation. nine0013

The logistics company we cooperate with helps with all these questions.

To find out the conditions and cost of delivery to Belarus, contact the representative of Bio Logistica LTD in Belarus by phone and they will advise you free of charge.

WhatsApp +7 999 542 02 88 (Russian speaking manager)

In this case, you get the opportunity to return VAT included in the price in the amount of 15% at the TAX FREE counter at the airport. Ben Gurion.

All documents required for the TAXFREE refund are processed at the pharmacy after the purchase.

Please note that VAT refunds do not apply to special offers.

Separation of antidepressants: what you need to know

contents

Some people need long-term use of antidepressants. But others may want to stop taking their medications. This may be due to unwanted side effects, changing medications, or simply because they feel like they no longer need the medication. nine0013

If you want to stop taking antidepressants, it's important to talk to your doctor about lowering your dose to zero rather than abruptly stopping your medication. This will avoid the withdrawal syndrome.

Symptoms and duration of withdrawal may be different for everyone. For most people, the symptoms are mild, but for others, they may be more severe and last longer. Common withdrawal symptoms include:

depression
anxiety
irritability
mood swings
flu-like symptoms, including excessive sweating, chills, aches and headaches
nausea or other stomach problems
dizziness
loss of appetite
insomnia
restless dreams, or other uncontrolled movement 9000 eg, tremors
sensitivity to sound or ringing in the ears
stiffness or pain in the limbs
brain shaking, which may look like you are getting an electric shock to the head

When you hear the word withdrawal, you may think of addiction or addiction. However, having withdrawal symptoms while on antidepressant medication does not mean you are addicted. Instead, the symptoms are due to your brain adapting after exposure to the drug.

Although all antidepressants can cause withdrawal symptoms, they are especially common with constriction:

selective serotonin reuptake inhibitors (SSRIs) such as escitalopram (Lexapro), sertraline (Zoloft) and paroxetine (Paxil)
serotonin and norepinephrine reuptake inhibitors (SNRIs), such as desvenlafaxine (Pristiq), duloxetine (Cymbalta), and venlafaxine (Effexor).

These drugs affect how your brain uses certain chemicals called neurotransmitters.

No matter which antidepressant you want to stop taking, don't try it yourself. Always talk to your doctor about the best way to remove a medication.

Tapering of antidepressants can be difficult. It can evoke many complex emotions. Keeping these tips in mind will make the process as easy as possible.

Talk to your doctor first

Always talk to your doctor about whether or not to reduce your medication. If they agree that narrowing is right for you, I can help you plan the best way to do it.

Give Antidepressants a Chance

Experts recommend taking antidepressants for at least six to nine months. Ideally, you should take them for at least six months after you feel better. nine0013

You may cut down on your antidepressants because you feel better, but it can also mean that the medication is working for you. Tapering too quickly reduces the likelihood of depression returning.

Know what affects your cone

How long your cone lasts depends on many factors, including:

the type of medication you are taking because some take longer to clear out of your body than others
your current dose drug, since higher doses usually require a longer constriction
have you had symptoms from previous medication changes that may cause your doctor to recommend slower tapering to try and avoid them

Be aware that tapering can take time find that the duration lasts longer or if you need it longer than other people you know who have taken their medications. They are all different and react differently.

Use mood calendar

A Mood Calendar can help you keep track of how you feel when you narrow your circle. Monitoring your daily mood can help you talk to your doctor if you have withdrawal symptoms, as well as determine if depression is returning.

Stick to healthy habits when you narrow your circle

Eat a healthy diet, exercise regularly, and reduce stress as much as possible. This can not only reduce the risk of narrowing symptoms, but also reduce the risk of depression in the future. nine0013

For example, a review of 25 studies found that exercise can help people cope with depression. Moderate to strenuous exercise was especially helpful.

Stay in touch with your doctor

Talk to your doctor about how you are feeling during your procedure, this will help them make adjustments if necessary so that you can narrow it down safely.

Ask family and friends for support

Narrowing can trigger a lot of emotions. This can help others support you and understand what is going on. nine0013

Consider talking therapy

Only one analysis showed that 20th place people taking antidepressants also receive psychotherapy. However, a meta-analysis study of antidepressants and psychotherapy found evidence that speech therapy during and after antidepressant tapering may be useful in preventing relapse or relapse.

Whether or not you have withdrawal symptoms during constriction, you may need to add talking therapy to your treatment. nine0013

End the entire process

End the entire process is important. Remember that your doctor is always there to help you. You should schedule monthly appointments to check for symptoms, adjust the cone if necessary, and make sure there is no recurrence of depression.

The time it takes to remove the medicine depends on the dose and how long you take the medicine. It also depends on the type of medication.

All medicines take some time to leave your body as they build up over time. If you experience withdrawal symptoms, they often begin around 90 percent of the drug is excreted from your body. The table below shows how long it takes for conventional antidepressants to leave your body.

Drug Time until drug is half the drug Time until drug is 99% cleared from the body SSRI citalopram (celexa) 36 hours 7.3 days sesitalopram (Lexapro) 27–32 hours 6.1 days paroxetine (Paxil) 24 hours 4.4 days fluoxetine (Prozac) 4 to 6 days 25 days sertraline (Zoloft) 26 hours 5. 4 days SNRIs duloxetine (Cymbalta) 12 hours 2.5 days venlafaxine (efexor) 5 hours 1 dandesvenlafaxine (Pristiq) 12 hours 2.5 days

Since mood swings are common withdrawal symptoms, it can sometimes be difficult to tell if you are feeling withdrawn or if you are depressed again. Several ways to tell the difference include:

Withdrawal symptoms begin within a few days of reducing the dose of the antidepressant or stopping the medication. Relapse symptoms usually start later, weeks or months after you start to shrink. They also appear gradually from the withdrawal syndrome. nine0004
Withdrawal and relapse have different physical symptoms. For example, while both can lead to insomnia, weaning is much more likely to cause flu-like symptoms and dizziness.
Withdrawal symptoms begin to disappear within a few weeks as your body adjusts to the new levels of neurotransmitters. Relapse symptoms usually last longer and may get worse.

Releasing antidepressants can be a good option for many people, but it's important to do it right.

Learn more