Side effects of stopping celexa

Citalopram (Celexa) | NAMI: National Alliance on Mental Illness

Brand names:

  • Celexa®
    • Tablets: 10 mg, 20 mg, 40 mg
  • Citalopram
    • Tablets: 10 mg, 20 mg, 40 mg
    • Liquid: 10 mg/5 ml

Generic name: citalopram (sye TAL oh pram)

All FDA black box warnings are at the end of this fact sheet.  Please review before taking this medication.

What Is Citalopram And What Does It Treat?

Citalopram is an antidepressant medication that works in the brain. It is approved for the treatment of major depressive disorder (MDD).

Symptoms of depression include:

  • Depressed mood - feeling sad, empty, or tearful
  • Feeling worthless, guilty, hopeless, and helpless
  • Loss of interest or pleasure in your usual activities
  • Sleep and eat more or less than usual (for most people it is less)
  • Low energy, trouble concentrating, or thoughts of death (suicidal thinking)
  • Psychomotor agitation (‘nervous energy’)
  • Psychomotor retardation (feeling like you are moving and thinking in slow motion)
  • Suicidal thoughts or behaviors

Citalopram may also be helpful when prescribed “off-label” for obsessive-compulsive disorder, generalized anxiety disorder, panic disorder, social phobia (also known as social anxiety disorder), posttraumatic stress disorder, eating disorders such as binge eating disorder, and premenstrual dysphoric disorder (PMDD). “Off-label” means that it hasn’t been approved by the Food and Drug Administration for this condition. Your mental health provider should justify his or her thinking in recommending an “off-label” treatment. They should be clear about the limits of the research around that medication and if there are any other options.

What Is The Most Important Information I Should Know About Citalopram?

Do not stop taking citalopram even when you feel better. With input from you, your health care provider will assess how long you will need to take the medicine.

Missing doses of citalopram may increase your risk for relapse in your symptoms.

Stopping citalopram abruptly may result in one or more of the following withdrawal symptoms: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin).

Depression is also a part of bipolar illness. People with bipolar disorder who take antidepressants may be at risk for "switching" from depression into mania. Symptoms of mania include "high" or irritable mood, very high self-esteem, decreased need for sleep, pressure to keep talking, racing thoughts, being easily distracted, frequently involved in activities with a large risk for bad consequences (for example, excessive buying sprees).

Medical attention should be sought if serotonin syndrome is suspected. Please refer to serious side effects for signs/symptoms.

Are There Specific Concerns About Citalopram And Pregnancy?

If you are planning on becoming pregnant, notify your health care provider to best manage your medications. People living with MDD who wish to become pregnant face important decisions. Untreated MDD has risks to the fetus, as well as the mother. It is important to discuss the risks and benefits of treatment with your doctor and caregivers. For women who take antidepressant medications during weeks 13 through the end of their pregnancy (second and third trimesters), there is a risk that the baby can be born before it is fully developed (before 37 weeks).

For mothers who have taken SSRIs during their pregnancy, there appears to be less than a 1% chance of infants developing persistent pulmonary hypertension. This is a potentially fatal condition that is associated with use of the antidepressant in the second half of pregnancy. However, women who discontinued antidepressant therapy were five times more likely to have a depression relapse than those who continued their antidepressant. If you are pregnant, please discuss the risks and benefits of antidepressant use with your health care provider.

Caution is advised with breastfeeding since citalopram does pass into breast milk.

What Should I Discuss With My Health Care Provider Before Taking Citalopram?

  • Symptoms of your condition that bother you the most
  • If you have thoughts of suicide or harming yourself
  • Medications you have taken in the past for your condition, whether they were effective or caused any adverse effects
  • If you experience side effects from your medications, discuss them with your provider. Some side effects may pass with time, but others may require changes in the medication.
  • Any other psychiatric or medical problems you have, including a history of bipolar disorder
  • All other medications you are currently taking (including over the counter products, herbal and nutritional supplements) and any medication allergies you have
  • Other non-medication treatment you are receiving, such as talk therapy or substance abuse treatment. Your provider can explain how these different treatments work with the medication.
  • If you are pregnant, plan to become pregnant, or are breastfeeding
  • If you drink alcohol or use drugs

How Should I Take Citalopram?

Citalopram is usually taken one time per day with or without food.

Typically patients begin at a low dose of medicine and the dose is increased slowly over several weeks.

The dose usually ranges from 20 mg to 40 mg once daily. For patients older than 60 years, the maximum recommended dose is 20 mg once daily. Only your health care provider can determine the correct dose for you.

The liquid should be measured with a dosing spoon or oral syringe which you can get from your pharmacy.

If you are taking citalopram, you should not take other medications that include escitalopram (Lexapro®).

Consider using a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member or friend to remind you or check in with you to be sure you are taking your medication.

What Happens If I Miss A Dose Of Citalopram?

If you miss a dose of citalopram, take it as soon as you remember, unless it is closer to the time of your next dose. Discuss this with your health care provider. Do not double your next dose or take more than what is prescribed.

What Should I Avoid While Taking Citalopram?

Avoid drinking alcohol or using illegal drugs while you are taking antidepressant medications. They may decrease the benefits (e. g., worsen your condition) and increase adverse effects (e.g., sedation) of the medication.

What Happens If I Overdose With Citalopram?

If an overdose occurs, call your doctor or 911. You may need urgent medical care. You may also contact the poison control center at 1-800-222-1222.

A specific treatment to reverse the effects of citalopram does not exist.

What Are The Possible Side Effects Of Citalopram?

Common side effects

Headache, nausea, diarrhea, dry mouth, increased sweating, feeling nervous, restless, fatigue, or having trouble sleeping (insomnia). These will often improve over the first week or two as you continue to take the medication.

Sexual side effects, such as problems with orgasm or ejaculatory delay often do not diminish over time.

Rare/serious side effects

Low sodium blood levels (symptoms of low sodium levels may include headache, weakness, difficulty concentrating and remembering), teeth grinding, angle closure glaucoma (symptoms of angle closure glaucoma may include eye pain, changes in vision, swelling or redness in or around eye), serotonin syndrome (symptoms may include shivering, diarrhea, confusion, severe muscle tightness, fever, seizures, and death), seizure

SSRI antidepressants including citalopram may increase the risk of bleeding events. Combined use of aspirin, nonsteroidal anti-inflammatory drugs (e.g., ibuprofen, naproxen), warfarin, and other anti-coagulants may increase this risk. This may include symptoms such as gums that bleed more easily, nose bleed, or gastrointestinal bleeding. Some cases have been life threatening.

Risk of abnormal heart rhythms with citalopram

August 2011: Citalopram at doses greater than 40 mg per day could potentially cause a dangerous abnormality in the electrical activity of the heart. Citalopram use is discouraged in patients with congenital long QT syndrome. Patients with low levels of potassium and magnesium in the blood are also at increased risk. If you are currently taking citalopram at a dose greater than 40 mg per days, talk to your health care professional. Seek immediate care if you experience an irregular heartbeat, shortness of breath, dizziness, or fainting while taking citalopram. If you are taking citalopram, your health care professional may occasionally order an electrocardiogram (ECG, EKG) to monitor your heart rate and rhythm. Your health care provider may also order tests to check levels of potassium and magnesium in your blood.

Are There Any Risks For Taking Citalopram For Long Periods Of Time?

To date, there are no known problems associated with long term use of citalopram. It is a safe and effective medication when used as directed.

What Other Medications May Interact With Citalopram?

Citalopram should not be taken with or within 2 weeks of taking monoamine oxidase inhibitors (MAOIs). These include phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®), rasagiline (Azilect®), and selegiline (Emsam®).

Although rare, there is an increased risk of serotonin syndrome when citalopram is used with other medications that increase serotonin, such as other antidepressants, migraine medications called “triptans” (e.g., Imitrex®), some pain medications (e.g., tramadol (Ultram®), the antibiotic linezolid (Zyvox®), and amphetamines.

Citalopram may increase the effects of other medications that can cause bleeding (e. g., ibuprofen (Advil®, Motrin®), warfarin (Coumadin®) and aspirin).

Increased risk of QT prolongation when used with:

  • Certain antiarrhythmics: quinidine (Quinidex Extentabs®, Quinaglute®, Quinalan®), procainamide (Procanbid®, Pronestyl®, Pronestyl-SR®), amiodarone (Cordarone®, Pacerone®), sotalol (Betapace®, Sorine®)
  • Certain antipsychotics: chlorpromazine (Thorazine®), thioridazine (Mellaril®)
  • Certain antibiotics: gatifloxacin (Tequin®), moxifloxacin (Avelox®)
  • Methadone®

How Long Does It Take For Citalopram To Work?

Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.

Summary of FDA Black Box Warnings

Suicidal thoughts or actions in children and adults

Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients with major depressive disorder (MDD), both adult and pediatric, may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in behavior, whether or not they are taking antidepressant medications. This risk may persist until significant remission occurs.

In short-term studies, antidepressants increased the risk of suicidality in children, adolescents, and young adults when compared to placebo. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24. Adults age 65 and older taking antidepressants have a decreased risk of suicidality. Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or health care professional. All patients being treated with antidepressants for any indication should watch for and notify their health care provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.


Provided by

(December 2020)

©2020 The College of Psychiatric and Neurologic Pharmacists (CPNP) and the National Alliance on Mental Illness (NAMI). CPNP and NAMI make this document available under the Creative Commons Attribution-No Derivatives 4.0 International License. Last Updated: January 2016.

This information is being provided as a community outreach effort of the College of Psychiatric and Neurologic Pharmacists. This information is for educational and informational purposes only and is not medical advice. This information contains a summary of important points and is not an exhaustive review of information about the medication. Always seek the advice of a physician or other qualified medical professional with any questions you may have regarding medications or medical conditions. Never delay seeking professional medical advice or disregard medical professional advice as a result of any information provided herein. The College of Psychiatric and Neurologic Pharmacists disclaims any and all liability alleged as a result of the information provided herein.

Symptoms, treatment, and when to call 911

Citalopram, which people may know by the brand name Celexa, is a drug that doctors commonly prescribe to treat depression. Stopping Celexa can cause withdrawal symptoms, even if a person does it gradually.

People report a wide range of Celexa withdrawal symptoms, including nausea, anxiety, and insomnia.

Restarting Celexa may relieve withdrawal symptoms, but this might not be a desirable solution for many people.

Other methods to prevent and treat Celexa withdrawal symptoms include drug tapering, which refers to gradually reducing the dosage over a fixed period, and cognitive behavioral therapy (CBT).

In this article, we discuss the symptoms of Celexa withdrawal and how to treat them.

Celexa is an antidepressant that belongs to the family of selective serotonin reuptake inhibitors (SSRIs). Doctors often prescribe SSRIs to treat depression in adults.

Celexa contains the active ingredient citalopram, which works as an antidepressant by increasing the amount of serotonin in the brain.

Experts suggest that depression occurs when there are imbalances in chemicals in the brain called neurotransmitters. Low serotonin in the brain may contribute to depressive symptoms.

The Food and Drug Administration (FDA) has only approved Celexa for the treatment of depression in adults. However, some doctors may prescribe the drug for other indications, such as:

  • alcohol use disorder
  • coronary arteriosclerosis
  • obsessive-compulsive disorder (OCD)
  • panic disorder
  • postmenopausal flushing
  • premenstrual dysphoric disorder

All SSRIs can potentially cause a person to experience withdrawal symptoms after discontinuing the drug. However, not everyone will experience these symptoms.

Clinical studies on Celexa withdrawal have shown that symptoms typically appear within a few days of stopping the drug and last a few weeks before gradually improving.

While people are most likely to experience withdrawal symptoms after abruptly stopping SSRIs, these symptoms can sometimes also occur with gradual tapering.

However, doctors still recommend tapering off Celexa over a period of several weeks to several months, depending on how long a person has been taking it.

In some cases, a person may experience withdrawal symptoms that start later or last longer than usual. Due to this, doctors may misinterpret a return of depressive symptoms as Celexa withdrawal.

The symptoms that people most commonly report after stopping Celexa are dizziness, anxiety, and irritability.

Other signs and symptoms of SSRI withdrawal may include:

  • lightheadedness
  • vertigo
  • shock-like sensations
  • burning or prickling sensation in the hands, legs, feet, and other parts of the body
  • fatigue
  • headaches
  • nausea
  • tremor
  • diarrhea
  • visual disturbances
  • insomnia

Some people also report hypersensitivity of the genitals and premature ejaculation.

In an article in Psychotherapy and Psychosomatics, researchers report three cases of people who experienced withdrawal symptoms from stopping Celexa.

All three participants had progressively lowered their dosage of Celexa before stopping the drug.

The symptoms of Celexa withdrawal appeared 1–5 days after completely stopping the drug, and they lasted between 1 week and 2 months.

People with Celexa withdrawal may need to speak with a doctor. The doctor may advise them to restart Celexa and gradually reduce their dosage.

They may also offer support for withdrawal symptoms, depending on the person’s experience.

Doctors sometimes recommend switching from Celexa to an SSRI with a longer half-life, such as fluoxetine (Prozac), which is less likely to cause withdrawal symptoms.

Other strategies may include group CBT and well-being therapy.

Repots show that some babies who have had exposure to Celexa during the third trimester have developed complications requiring long hospital stays involving breathing support and tube feeding.

However, stopping Celexa during pregnancy can lead to withdrawal symptoms and, more significantly, a return of depressive symptoms.

As untreated depression can cause health concerns for both the baby and the pregnant person, doctors will need to weigh the benefits and risks of stopping Celexa during the third trimester of pregnancy.

Possible risks for the baby include:

  • prematurity
  • low birth weight
  • intrauterine growth restriction

Untreated depression during pregnancy can also affect the child’s development, potentially leading to:

  • higher impulsivity
  • dysfunctional social interactions
  • cognitive, behavioral, and emotional difficulties

It may also affect the pregnant person, putting them at higher risk of postpartum depression and suicidality.

Other associations include increased hospital admissions and preeclampsia. Pregnant people with untreated depression may also be more likely to engage in risky behaviors, such as:

  • smoking
  • illicit drug use
  • unhealthy alcohol use
  • poor nutrition

People experiencing Celexa withdrawal may need to speak with a doctor if the symptoms affect their everyday life.

The doctor can help them decide whether to restart Celexa or start a new SSRI with a lower risk of withdrawal symptoms.

Dealing with Celexa withdrawal may not always require restarting antidepressant therapy. In some cases, doctors may recommend psychotherapy.

Anyone experiencing suicidal thoughts or a return of severe depressive symptoms may need to call 911 for emergency help.

Some people experience prolonged periods of Celexa withdrawal symptoms.

For example, people using SSRIs for long-term treatment may experience persistent withdrawal symptoms on stopping. These can include:

  • disturbed mood
  • depression
  • emotional lability
  • mood swings
  • anxiety
  • difficulty concentrating
  • impaired memory

Anyone experiencing prolonged Celexa withdrawal symptoms should speak with a doctor.

People who stop taking Celexa may experience withdrawal symptoms, particularly following long-term use of the drug.

Withdrawal symptoms can occur after suddenly or progressively stopping the drug. The symptoms of Celexa withdrawal and their intensity may vary from person to person.

People experiencing troubling Celexa withdrawal symptoms should speak with a doctor, who can help them find ways to manage the symptoms.

Severe depressive symptoms and suicidality require immediate medical attention.

Celexa Side Effects: What You Need to Know


If you are looking for treatment options for depression, your doctor may suggest Celexa (citalopram) for your condition. This is a prescription medication used to treat depression in adults.

Celexa comes as a tablet that you take by mouth. Usually used as a long term treatment. For more information about Celex, see this detailed drug article.

Like all medicines, Celexa can cause mild or serious side effects. Keep reading to find out more.

What are the most common side effects of Celexa?

Some people may experience mild or severe side effects while taking Celexa. Examples of commonly reported side effects of Celexa may include:

  • nausea
  • drowsiness
  • dry mouth
  • insomnia (trouble sleeping)*
  • sweating more than usual

See below for other possible mild and serious side effects of Celexa.

What are the mild side effects of Celexa?

Celexa may cause mild side effects in some people.

Examples of mild side effects reported with Celexa include:

  • sexual problems in women and men*†
  • weight gain or weight loss*
  • insomnia (sleep problems)*

In most cases, these side effects should be temporary. Some of them are easy to manage too. But if you have any symptoms that continue or bother you, talk to your doctor or pharmacist. And don't stop taking Celexa unless your doctor tells you to.

Celexa may cause mild side effects other than those listed above. See the Celexa Medication Guide for details.

After the Food and Drug Administration (FDA) approves a drug, it monitors and analyzes the drug's side effects. If you would like to notify the FDA of a side effect you had with Celexa, visit MedWatch.

What are the serious side effects of Celexa?

Rarely, serious side effects may occur with Celexa. Serious side effects reported with Celexa include:

  • Suicidal thoughts and behavior in children and young adults*
  • Withdrawal symptoms when the drug is stopped abruptly†
  • Bruising or bleeding more easily than usual
  • Abnormal heart rhythms
  • hypomania or mania (episodes of high energy and excitement)
  • low blood sodium
  • seizures
  • serotonin syndrome (high levels of a brain chemical called serotonin)
  • allergic reaction‡

If you develop serious side effects while taking Celexa, call your doctor right away. If the side effects seem life-threatening or if you think you need a medical emergency, call 911 or your local emergency number right away.

Side effects in children

Celexa is not approved for use in children. But in some cases, the drug can be used off-label to treat depression in children. Off-label use of a drug means the use of a drug for purposes other than those for which it has been approved by the Food and Drug Administration (FDA).

If you have questions about whether your child can take Celexa, talk to their doctor.

It is important to note that Celexa has a boxed warning for the risk of suicidal thoughts and behavior in children and young adults (ages 18 to 24). The boxed warning is the most severe warning from the FDA. It warns doctors and patients about drug side effects that can be dangerous.

See the "Explanation of Side Effects" section below for details.

Frequently Asked Questions About Celexa Side Effects

Below are answers to some frequently asked questions about Celexa side effects.

Do I have a higher risk of side effects during the first week of taking Celexa?

Yes, you may have a higher risk of certain side effects during the first week of taking Celexa.

For example, the risk of suicidal thoughts and behavior* is highest when taking Celexa immediately after you start taking the drug.

To reduce the risk of side effects from Celexa, your doctor will start with a low dose of Celexa. They may slowly increase your dosage over time until the symptoms of your condition begin to ease. For detailed dosage information, see this detailed drug article.

Will I experience withdrawal side effects if I stop taking Celexa?

Yes, you may experience withdrawal side effects if you suddenly stop taking Celexa.

Withdrawal side effects are symptoms that can occur when you stop taking a drug that your body has become addicted to. Examples of withdrawal side effects that may occur with Celexa include:

  • agitation
  • weakness
  • dizziness
  • drowsiness
  • dry mouth
  • insomnia (trouble sleeping)
  • nausea and vomiting

You should not stop taking Celexa unless your doctor tells you it is safe to do so. When it's time to stop taking Celexa, your doctor will gradually decrease your dosage. This helps reduce the risk of side effects of withdrawal after stopping treatment with Celexa.

Does Celexa cause any long term side effects?

Possibly. Most Celexa side effects improve or disappear within hours or days of taking the drug. But in rare cases, the side effects of Celexa can last longer.

For example, there have been reports of sexual problems* caused by antidepressants (such as Celexa) persisting for several weeks or months after stopping treatment. These long-term sexual problems were reported after antidepressants were released to the market.

Since Celexa was approved, abnormal heart rhythm (a rare side effect) has been reported in very rare cases to cause long-term, life-threatening heart problems.

If you have questions about what to expect from Celexa treatment, talk to your doctor or pharmacist.

Do the side effects of Celexa change depending on the dose I take (10 mg, 20 mg or 40 mg)?

Yes, the side effects of Celexa can vary depending on the strength of the drug you are taking.

For example, your risk of abnormal heart rhythms from Celexa is higher if you take higher doses of the drug.

Talk to your doctor or pharmacist if you have any questions about the risk of certain side effects from Celexa or what concentration is right for your condition.

How long do the side effects of Celexa usually last?

Most side effects of Celexa last from a few hours to a few days after starting treatment. But the duration of side effects from the drug can be different for each person taking Celexa.

For more information about what to expect from Celexa treatment, talk to your doctor or pharmacist.

Side effects explained

Find out more about some of the side effects Celexa may cause.

Sexual problems in women and men

Sexual problems are a common side effect of Celexa. These side effects can occur in both women* and men* taking the drug.

Sexual problems in men taking Celexa may include:

  • delayed ejaculation (when ejaculation requires more than 30 minutes of sexual stimulation)
  • erectile dysfunction (inability to get or maintain an erection sufficient for intercourse)
  • low libido (sex drive)

Sexual problems in women taking Celexa may include:

  • orgasm problems
  • low libido

Be aware that the depression that Celexa is used to treat can also cause sexual problems. Therefore, it can be difficult to tell if these side effects are caused by Celexa or the disease you are taking the drug to treat.

What can help

If you have sexual problems while taking Celexa, talk to your doctor. They can help determine if these side effects are related to your condition or to a drug.

Weight gain or weight loss

Weight gain and weight loss are common side effects of Celexa. But some weight changes may not be caused by Celexa itself. The depression that Celexa is used to treat can also cause weight changes. Therefore, a change in weight after you start taking Celexa may be a sign that the drug is working to treat your condition.

What can help

If you are concerned about weight gain or loss while taking Celexa, talk to your doctor. They may suggest ways to manage your weight during treatment.

Insomnia (trouble sleeping)

Insomnia is a common side effect of Celexa. The drug may also cause other sleep problems in some people. For example, instead of insomnia, you may feel sleepy after taking Celexa.

You will usually learn more about how Celexa affects you after you have taken several doses of the drug.

What can help

Talk to your doctor if you have insomnia or other sleep problems because of Celexa. They may recommend ways to manage this side effect.

Suicidal ideation and behavior in children and young adults

Selexa has a boxed warning for suicidal ideation and behavior. The boxed warning is the most serious warning from the Food and Drug Administration (FDA).

This risk affects children and young adults (aged 18 to 24) who take antidepressants such as Celexa. It is important to note that Celexa is not approved for use in people under 18 years of age.

Regardless of age, this risk is highest during the first few months of treatment and after any dosage changes.

While you are taking Celexa, you should watch for the following symptoms:

  • restlessness
  • hypomania or mania (episodes of high energy and agitation)
  • impulsive behavior
  • insomnia (sleep problems)
  • mood changes such as agitation, aggressiveness, hostility and irritability
  • panic attacks
  • feelings of anxiety

for which Celexa is used.

What can help

Tell your doctor right away if you have any unusual changes in mood, behavior, thoughts, or feelings while taking Celexa. They may ask you to stop taking Celexa and switch to another drug to treat your condition.

If you have thoughts of harming yourself, call 911 or your local emergency number immediately.

Suicide Prevention

If you think someone is at immediate risk of harming themselves or harming another:

  • Call 911 or your local emergency number.
  • Stay with the person until help arrives.
  • Remove all weapons, knives, medicines, and other items that could cause harm.
  • Listen, but don't judge, argue, threaten or yell.

If you or someone you know is thinking about suicide, get help from a crisis or suicide prevention hotline. Call the National Suicide Prevention Hotline at 800-273-8255.

Allergic reaction

Like most medicines, Celexa can cause an allergic reaction in some people. This side effect was not reported in studies of the drug. But ever since Celexa became available for use, allergic reactions have been reported.

Symptoms may be mild or severe and may include:

  • skin rash
  • itching
  • erythema (temporary warmth, redness or discoloration of the skin)
  • swelling under the skin, usually on the eyelids, lips, arms or legs
  • swelling of the mouth, tongue, or throat that makes breathing difficult
What may help

If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. They may suggest an over-the-counter oral antihistamine such as Benadryl (diphenhydramine) or a topical product such as hydrocortisone cream to relieve your symptoms.

If your doctor confirms that you had a mild allergic reaction to Celexa, he or she will decide whether you should continue taking Celexa.

If you have symptoms of a severe allergic reaction, such as swelling or difficulty breathing, call 911 or your local emergency number right away. These symptoms can be life threatening and require immediate medical attention.

If your doctor confirms that you have had a serious allergic reaction to Celexa, he may ask you to switch to another treatment.

Tracking side effects

While on Celexa, consider keeping a record of any side effects you experience. You can then share this information with your doctor. This is especially helpful when you first start taking new medications or using a combination of treatments.

Your side effect notes may include things like:

  • what dose of the drug you were taking when you had the side effect
  • How soon after starting this dose did you experience a side effect
  • What were your symptoms due to the side effect
  • How did it affect your daily activities
  • What other medications did you also take
  • Any other information you think Important

Taking notes and sharing them with your doctor will help him learn more about how Celexa affects you. Your doctor may use this information to adjust your treatment plan if necessary.

Celexa Warnings

It may not be safe to take Celexa in certain situations. Read on to learn more about possible warnings for Celexa.

Boxed Warning: Suicidal Thoughts and Behaviors in Children and Young Adults

Selexa has a boxed warning for suicidal thoughts and behaviors. The boxed warning is the most serious warning from the Food and Drug Administration (FDA).

This risk affects children and young adults (aged 18 to 24) who take antidepressants such as Celexa. It is important to note that Celexa is not approved for use in people under 18 years of age.

See the "Explanation of Side Effects" section above for more information.

Other warnings

Celexa may not be right for you if you have certain medical conditions or other health conditions. Talk to your doctor about your medical history before taking Celexa. The list below includes factors to consider.

Angle-closure glaucoma. Before starting treatment with Celexa, tell your doctor if you have angle-closure glaucoma. The drug may increase the risk of an attack of glaucoma (a sudden worsening of glaucoma that leads to blurred vision and pain in the eyes). If you develop these symptoms while taking Celexa, call 911 or your local emergency number immediately.

Bipolar disorder. Celexa may cause hypomania or mania (episodes of high energy and arousal that may be associated with bipolar disorder). Tell your doctor if you have bipolar disorder before taking Celexa. They may prescribe a drug other than Celexa for your condition.

Bleeding problems. Celexa may increase the risk of bleeding. If you already have bleeding problems, your risk of this side effect may be even higher. Tell your doctor if you have any bleeding problems before taking Celexa.

Heart problems. Celexa may cause abnormal heart rhythms. You may be at a higher risk of this side effect if you already have heart problems. Tell your doctor if you have any heart problems, such as heart failure or a recent heart attack, before taking Celexa.

Liver or kidney problems. If you have liver or kidney problems, your body may have trouble getting Celexa out of your system. This may increase the risk of side effects from the drug. Tell your doctor about any liver or kidney problems you have before taking Celexa.

Low blood sodium. Celexa may cause low blood sodium levels. If you already have low sodium, talk to your doctor before taking Celexa.

Seizures. Celexa may cause convulsions. If you already had seizures before taking the drug, your risk of this side effect may be even higher while taking Celexa. Tell your doctor if you have seizures before taking Celexa.

Allergic reaction. If you have had an allergic reaction to Celexa or any of its ingredients, your doctor will likely not prescribe Celexa. Ask your doctor which other medicines are best for your condition.

Use of monoamine oxidase inhibitors (MAOIs). MAOIs are a group of drugs used to treat depression. Before you start Celexa, tell your doctor if you are taking an MAOI. Taking these drugs together may increase the risk of serotonin syndrome. Because of this, you should not take Celexa if you are taking an MAOI. Your doctor will ask you to wait 2 weeks or more after you stop taking an MAOI before you start taking Celexa. And if you stop taking Celexa, your doctor will suggest that you wait at least 2 weeks before starting an MAOI.

Drinking alcohol and Celexa

It is recommended to avoid drinking alcohol while taking Celexa. Drinking alcohol while taking Celexa may cause problems with clear thinking or muscle coordination.

If you drink alcohol, talk to your doctor before taking Celexa.

Pregnancy and breastfeeding while taking Celexa

Taking Celexa while pregnant or breastfeeding may not be safe.

If you are pregnant or breastfeeding, planning to become pregnant or breastfeeding, talk to your doctor about the risks and benefits of taking Celexa.

What to ask your doctor

Celexa is used to treat depression in adults. Some people who take Celexa may experience mild side effects. In rare cases, serious side effects may also occur.

If you have any questions about the side effects of Celexa, talk to your doctor or pharmacist. Here are some questions you can ask:

  • What are the side effects of Selexa compared to the side effects of similar drugs such as Lexapro (escitalopram)?
  • How can I manage the side effects that I may have with Celexa?
  • Do I have other health conditions that could increase my risk of side effects while taking Celexa?
  • Are there any side effects of Celexa that I should tell you about right away?

To read first-hand stories of people coping with their condition, subscribe to Drink-Drink's depression newsletter.

Ask a pharmacist


Are there any medicines that can increase the risk of side effects if I take them with Celexa?



Yes, taking certain medications with Celexa can increase the risk of side effects. Examples of such drugs include:

Certain CYP2C19 inhibitors. Taking Celexa with these drugs may increase the risk of side effects of Celexa, including irregular heartbeats (rare side effects). Examples of CYP2C19 inhibitorsinclude omeprazole (Prilosec), cimetidine (Tagamet), and voriconazole (Vfend).

Non-steroidal anti-inflammatory drugs (NSAIDs). Taking NSAIDs with Celexa may increase the risk of bleeding. Examples of these drugs include naproxen (Aliv), ibuprofen (Advil), and meloxicam (Mobic).

Anticoagulants and antiplatelet agents (blood thinners). Taking these drugs with Celexa may increase the risk of bleeding. Examples of blood thinners include clopidogrel (Plavix), warfarin (Coumadin), rivaroxaban (Xarelto), apixaban (Eliquis), and aspirin (Bayer, Ecotrin, Saint Joseph Low, and others).

Antipsychotics. Taking antipsychotics with Celexa may increase the risk of serotonin syndrome. Examples of these drugs include aripiprazole (Abilify) and quetiapine (Seroquel).

Certain oral antifungals. Taking Celexa with certain antifungal medicines you take by mouth may increase the risk of heart rhythm problems while taking Celexa. Examples of these antifungals include ketoconazole and itraconazole.

The above list does not include all drugs that may interact with Celexa. Before starting treatment with Celexa, tell your doctor and pharmacist about all prescription and over-the-counter medicines you are taking. They can determine if they are safe to use with Celexa.

Elisabeth Scheffel, PharmD, BCACP, CDCES Answers represent the opinions of our medical experts. All content is for informational purposes only and should not be considered medical advice.

Registration data: Drink-Drink has made every effort to ensure that all information is accurate, complete and up to date. However, this article should not be used as a substitute for the knowledge and experience of a licensed healthcare professional. You should always check with your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or side effects. The absence of warnings or other information for a given medicinal product does not mean that the drug or combination of drugs is safe, effective, or suitable for all patients or for all specific uses.

Celexa and MDMA | Interactions and mixing effects

Celexa and MDMA

  1. Name: Celexa and MDMA
  2. Author Philippa Gold
  3. Edited by Hugh Soames
  4. Reviewed Dr. Ruth Arenas
  5. celexa and MDMA : At Worlds Best Rehab, we are committed to providing the most up-to-date and accurate health information on the Internet so that our readers can make informed decisions about their health care. Our subject matter experts specialize in addiction treatment and behavioral therapy. We follow strict guidelines when verifying information and use only reliable sources when citing statistical data and medical information. Look for the icon in our articles for the latest and most accurate information. If you believe that any of our content is inaccurate or out of date, please let us know via our contact page,
  6. Must read disclaimer : The world's best rehab recovery blog aims to improve the quality of life for people struggling with addiction and mental health issues. We use fact-based content and publish material that is researched, cited, edited and reviewed by professionals. The information we publish is not intended to replace professional medical advice, diagnosis or treatment. It should not be used as a substitute for the advice of your doctor or other qualified health care provider. In case of a medical emergency, contact the emergency services immediately.
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MDMA, the full name is methylenedioxymethylamphetamine. A bit boring, so most people just call it MDMA, Ecstasy, Molly, Mum and Dad, X, E, or XTC, Disco Biscuits, Thizz, and all the other street names that might confuse the uninitiated user a bit.

Can Celexa be mixed with MDMA?

Before we continue talking about celex and MDMA, disclaimer : The world's best rehab blog aims to improve the quality of life for people struggling with addiction and mental health issues. We use fact-based content and publish material that is researched, cited, edited and reviewed by professionals. The information we publish is not intended to replace professional medical advice, diagnosis or treatment. It should not be used as a substitute for the advice of your doctor or other qualified health care provider.

To be honest, we don't recommend mixing Celexa with MDMA. If you are using it for entertainment, why bother? Celexa does not enhance the effects of MDMA and can cause serious complications that will really ruin your evening. For example, death, which is always a risk when mixing MDMA and Celexa.

When mixed with Celexa, MDMA may interfere with the body's ability to maintain the correct temperature. Indeed, this can also be caused by taking MDMA in large amounts without mixing with Celexa. Users sometimes experience a dangerous rise in body temperature (hyperthermia), which can lead to liver, kidney or heart failure, or even (as we said) death.

Celexa-MDMA interaction

If you're looking for an interaction between Celexa and MDMA, remember that with MDMA there's really no way to tell what it's been diluted with or mixed with. Pure MDMA, meaning it has no other substances, is not a safe drug. MDMA on its own and even without celexa can have the same effects as other stimulants such as cocaine and amphetamines. A person taking ecstasy may experience increased heart rate and blood pressure, muscle tension, involuntary clenching of teeth, nausea, blurred vision, weakness, chills, or sweating.

Since MDMA is not pure, you are not aware of the interaction with Celexa in your body.

MDMA is as likely to be mixed with other substances as any other drug. A supposedly "clean" Molly might contain ephedrine (a stimulant), dextromethorphan (a cough suppressant), ketamine, caffeine, cocaine, methamphetamine, or even bath salts. The fact that it comes in crystal or powder form and not tablets like ecstasy does not prove that it is pure. In this case, it is impossible to accurately predict the effect of mixing Celexa and MDMA in your body. Indeed, the chemical reactions of MDMA and Celex in your body can be completely different than someone else taking the exact same amount of Celex and MDMA, due to individual physiology.

According to the National Institute on Drug Abuse (NIDA), a significant percentage of molly or ecstasy contains some level of impurities. So it's not just the effects of mixing Celexa and Molly. We are talking about mixing MDMA, Celex and everything else that is used as a diluent.

Common items used to cut MDMA

  • Paramethoxyamphetamine (PMA) or MDEA
  • Aspirin
  • Caffeine
  • Methamphetamine or amphetamine
  • Cocaine
  • Bath salts, including preparations such as mephedrone
  • butylone
  • Ketamine
  • LSD

Unfortunately, the DEA also reported that “over 80 different unique substances have been sold as MDMA. Many drugs sold as "Molly" or "Ecstasy" do not contain MDMA at all." What worries you, in any case, you decide to look at it.

celex, MDMA and fentanyl

What the above list of cutting agents does not reveal is probably the most agonizing thing that has come up in the last few years. This is the widespread and unqualified use of fentanyl as a cutting agent for MDMA and other drugs. Many people now use MDMA for recreational purposes. It's illegal. And most people are informed enough to balance the risk (both prosecution and health) of taking MDMA and mixing MDMA with Celexa.

Most people don't haggle over a huge lethal dose of Fentanly thinking it's MDMA. Completely wrong. An unacceptable behavior in the eyes of many, but a seemingly acceptable practice for those involved in the sale and production of MDMA. When we mix fentanl with MDMA and then {fuldrug}, there's a chance of a massive myocardial infarction... a.k.a. a heart attack. And usually death.

Isn't MDMA safe? Then surely celexa and MDMA are also safe?

No drug is "safe". Such is the nature of drugs! If they can be 100% avoided, then great. If not. Learn about all the facts and interactions between drugs. With regard to MDMA, there has been a lot of news recently about medically supervised clinical trials. Psilocybin and MDMA are two of the promising psychedelic drugs for mental illness treatments. A recent phase 3 trial of MDMA and talk therapy for people suffering from post-traumatic stress disorder has shown positive results. However, these are limited medical trials. They do not in any way support the use of MDMA or the mixing of Celexa and MDMA.

Mixing drugs is not something to be taken lightly, if you are on Celexa and also use alcohol or weed, you can explore the effects here. The effects of selex and weed or the effects of celex and alcohol or celex and cocaine.

Celexa vs. MDMA

MDMA vs. Celexa

3,4-methyl Endioxy Methamphetamine ( MDMA ) commonly found in 9 tablet form 6 tablets0655 ecstasy ) and crystalline form ( Molly or Mandy ), is a potent central nervous system (CNS) stimulant that is primarily used for recreational purposes. Desired effects include altered sensations, increased energy, empathy, and pleasure. When taken orally, effects begin in 30 to 45 minutes and last 3 to 6 hours.

MDMA was first developed in 1912 by Merck. It has been used to enhance psychotherapy since 1970s and became popular as a street drug in the 1980s. MDMA is commonly associated with dance parties, raves and electronic dance music. It can be mixed with other substances such as ephedrine, amphetamine and methamphetamine. In 2016, about 21 million people aged 15 to 64 used ecstasy (0.3% of the world's population). This was broadly similar to the percentage of people using cocaine or amphetamines, but lower than cannabis or opioids. In the United States, as of 2017, about 7% of people have used MDMA at some point in their lives, and 0.9% used it in the last year.

Short-term side effects include teeth grinding, blurred vision, sweating and heart palpitations, and long-term use can also lead to addiction, memory problems, paranoia, and trouble sleeping. Deaths due to fever and dehydration have been reported. After use, people often feel depressed and tired. MDMA works primarily by increasing the activity of the neurotransmitters serotonin, dopamine and norepinephrine in parts of the brain. It belongs to the substituted amphetamine drug classes and has stimulant and hallucinogenic effects.

MDMA is banned in most countries. and has limited medical approval
in a small number of countries. In the United States, the Food and Drug Administration is currently evaluating the drug for clinical use. Canada has allowed limited distribution of MDMA and other psychedelics such as psilocybin upon application and approval from Health Canada.

Overdose effects of celexa and MDMA

According to recent data, about 119,000 people in the US alone are receiving treatment for problems related to ecstasy and MDMA. In addition, one study found that 19,458 people died from psychostimulants, including MDMA, in 2019.

But the answer to the question: "Can you overdose on ecstasy?" not quite straight forward. While it is possible to die as a result of using ecstasy, death from this drug is not necessarily a direct result of overuse, but rather due to side effects. And when Celexa and MDMA are mixed, these side effects can increase rapidly and exponentially.

According to medical experts, direct death from MDMA and ecstasy use is usually associated with overheating. MDMA interferes with the body's ability to regulate temperature, and Celexa further interferes with this process. When people are then in warm conditions or dancing, the risk of overheating is higher. The medical term for this is hyperthermia, and with hyperthermia people are at increased risk:

  • Dehydration
  • Cerebral edema
  • Muscle disorder
  • Electrolyte imbalance
  • Violation of the organ

Celexa and MDMA for emergencies

Many ecstasy "overdoses" are the direct result of additives in the pills themselves, such as the fentanly we talked about earlier. When MDMA users arrive at a hospital or rehab center, doctors and staff are not immediately aware of what percentage of the pills they ingested was MDMA compared to other supplements, or what other substances (legal or illegal) were ingested, such as celexa. and MDMA. This requires a blood toxicology test, and while the results are pending, healthcare professionals will do their best to treat dehydration and overheating. 1

When the patient's condition stabilizes, there is a good chance of a full recovery. However, some cases of ecstasy overdose can be fatal, especially when using fentanyl and other very dangerous cutting agents.

If you've used MDMA and ecstasy and find it hard to stop, it's probably time to get help. Don't risk overdosing or developing a chronic addiction.

If you are taking celex and also use alcohol or MDMA, you can research the effects of celex and alcohol as well as the signal of celex and weed and celex and cocaine here.

For the effects of other drugs and weeds, refer to our Weeds and Other Drugs List A to L or our Weeds and Other Drugs List MZ.

Or you can find what you are looking for in our A to L Alcohol and Other Drugs Index or M to Z Alcohol and Other Drugs Index or our A to L MDMA and Other Drugs Index or MDMA and Others Index drugs from M to Z, or Cocaine and other drugs Index from A to L or Index of cocaine and other drugs from M to Z.

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If you want to stop taking MDMA or Celexa, you may experience withdrawal symptoms. MDMA withdrawal can be explored here, and Celexa withdrawal can be found on our Withdrawal Index.

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Recommendations: Celexa and MDMA

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