Does abilify work immediately
Aripiprazole (Abilify) | NAMI: National Alliance on Mental Illness
Brand names:
-
- Tablet: 2 mg, 5mg, 10 mg, 15 mg, 20 mg, 30 mg
- Abilify MyCite®
- Oral tablet with a digestible sensor: 2 mg, 5 mg, 10 mg, 15 mg, 20 mg, 30 mg
- Abilify Maintena®
- Extended-release injectable suspension: 300 mg, 400 mg
- Aristada® (aripiprazole lauroxil)
- Extended-release injectable suspension: 441 mg, 662 mg, 882 mg, 1064 mg
- Aristada Initio® (aripiprazole lauroxil)
- Extended-release injectable suspension: 675 mg
Generic name: aripiprazole (ay ri PIP ray zole), aripiprazole lauroxil (law rox il)
- Aripiprazole
- Oral tablet: 2 mg, 5mg, 10 mg, 15 mg, 20 mg, 30 mg
- Orally disintegrating tablet: 10 mg, 15 mg
- Oral solution: 1 mg/mL
All FDA black box warnings are at the end of this fact sheet. Please review before taking this medication.
What Is Aripiprazole And What Does It Treat?
Aripiprazole is a medication that works in the brain to treat schizophrenia. It is also known as a second-generation antipsychotic (SGA) or atypical antipsychotic. Aripiprazole rebalances dopamine and serotonin to improve thinking, mood, and behavior.
Symptoms of schizophrenia include:
- Hallucinations – imagined voices or images that seem real
- Delusions - beliefs that are not true (e.g., other people are reading your thoughts)
- Disorganized thinking or trouble organizing your thoughts and making sense
- Little desire to be around other people
- Trouble speaking clearly
- Lack of motivation
Aripiprazole may help some or all of these symptoms.
Aripiprazole is also FDA approved for the following indications:
- Acute treatment of manic or mixed episodes of bipolar disorder (when used alone or with lithium or valproate)
- Maintenance (long-term) treatment of bipolar disorder
- Adjunctive treatment of major depressive disorder.
This means aripiprazole is used in addition to an antidepressant to help treat depression. - Irritability associated with autistic disorders
- Tourette’s syndrome
This medication sheet will focus primarily on schizophrenia. You can find more information about bipolar disorder, depression, and autism spectrum disorders here.
Aripiprazole may also be helpful when prescribed “off-label” for borderline personality disorder or drug-induced hyperprolactinemia (elevated prolactin levels caused by other antipsychotics). “Off-label” means that it hasn’t been approved by the Food and Drug Administration for this condition. Your mental health provider should justify his or her thinking in recommending an “off-label” treatment. They should be clear about the limits of the research around that medication and if there are any other options.
What Is The Most Important Information I Should Know About Aripiprazole?
Schizophrenia requires long-term treatment.
Do not stop taking aripiprazole, even when you feel better.
With input from you, your health care provider will assess how long you will need to take the medicine.
Missing doses of aripiprazole may increase your risk for a relapse in your symptoms.
Do not stop taking aripiprazole or change your dose without talking with your health care provider first.
For aripiprazole to work properly, it should be taken every day as ordered by your health care provider.
Are There Specific Concerns About Aripiprazole And Pregnancy?
If you are planning on becoming pregnant, notify your health care provider to best manage your medications. People living with schizophrenia who wish to become pregnant face important decisions. This is a complex decision since untreated schizophrenia has risks to the fetus, as well as the mother. It is important to discuss the risks and benefits of treatment with your doctor and caregivers.
Antipsychotic use during the third trimester of pregnancy has a risk for abnormal muscle movements (extrapyramidal symptoms [EPS]) and/or withdrawal symptoms in newborns following delivery.
Symptoms in the newborn may include agitation, feeding disorder, hypertonia, hypotonia, respiratory distress, somnolence, and tremor; these effects may be self-limiting or require hospitalization.
In general, infants exposed to SGAs via breast milk should be monitored weekly for the first month of exposure for symptoms, such as appetite changes, insomnia, irritability, or lethargy.
Caution is advised with breastfeeding since aripiprazole does pass into breast milk.
What Should I Discuss With My Health Care Provider Before Taking Aripiprazole?
- Symptoms of your condition that bother you the most
- If you have thoughts of suicide or harming yourself
- Medications you have taken in the past for your condition, whether they were effective or caused any adverse effects
- If you ever had muscle stiffness, shaking, tardive dyskinesia, neuroleptic malignant syndrome, or weight gain caused by a medication
- If you experience side effects from your medications, discuss them with your provider.
Some side effects may pass with time, but others may require changes in the medication. - Any psychiatric or medical problems you have, such as heart rhythm problems, long QT syndrome, heart attacks, diabetes, high cholesterol, or seizures
- If you have a family history of diabetes or heart disease
- All other medications you are currently taking (including over the counter products, herbal and nutritional supplements) and any medication allergies you have
- Other non-medication treatment you are receiving, such as talk therapy or substance abuse treatment. Your provider can explain how these different treatments work with the medication.
- If you are pregnant, plan to become pregnant, or are breastfeeding
- If you smoke, drink alcohol, or use illegal drugs
How Should I Take Aripiprazole?
Aripiprazole tablets and suspension are usually taken 1 time per day with or without food.
Typically, patients begin at a low dose of medicine and the dose is increased slowly over several weeks.
The oral dose of aripiprazole usually ranges from 2 mg to 30 mg taken once daily. The dose of aripiprazole maintena extended-release injection ranges from 300 mg to 400 mg given once monthly; the dose of aripiprazole lauroxil extended-release injection ranges from 441 mg to 1064 mg – depending on the dose, it is given once per month, every 6 weeks, or every 2 months. Aripiprazole Maintena requires a two-week oral medication overlap; aripiprazole lauroxil requires a three-week oral overlap. Aripiprazole lauroxil Initio is typically given after an oral dose of aripiprazole along with an aripiprazole lauroxil injection – this allows for a one-day initiation and does not require further oral overlap. Only your health care provider can determine the correct formulation and dose for you.
Use a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member or a friend to remind you or check in with you to be sure you are taking your medication.
What Happens If I Miss A Dose Of Aripiprazole?
If you miss a dose of oral aripiprazole, take it as soon as you remember, unless it is closer to the time of your next dose. Do not double your next dose or take more than what is prescribed. If you miss an injection, call your doctor or pharmacist right away. Discuss this with your health care provider.
What Should I Avoid While Taking Aripiprazole?
Avoid drinking alcohol or using illegal drugs while you are taking aripiprazole. They may decrease the benefits (e.g., worsen your confusion) and increase adverse effects (e.g., sedation) of the medication.
What Happens If I Overdose With Aripiprazole?
If an overdose occurs call your doctor or 911. You may need urgent medical care. You may also contact the poison control center at 1-800-222-1222.
A specific treatment to reverse the effects of aripiprazole does not exist.
What Are Possible Side Effects Of Aripiprazole?
Common side effects
Headache, extrapyramidal symptoms, drowsiness, restlessness, fatigue, sedation, agitation, insomnia, anxiety, weight gain, cholesterol abnormalities, increased glucose, nausea, vomiting, constipation, application site rash (MyCite), tremor
Rare/serious side effects
Rash, dry mouth, muscle aches, seizure, agitation
Aripiprazole may increase the blood levels of a hormone called prolactin.
Side effects of increased prolactin levels include females losing their period, production of breast milk and males losing their sex drive or possibly experiencing erectile problems. Long term (months or years) of elevated prolactin can lead to osteoporosis or increased risk of bone fractures.
Some people may develop muscle-related side effects while taking aripiprazole. The technical terms for these are “extrapyramidal symptoms” (EPS) and “tardive dyskinesia” (TD). Symptoms of EPS include restlessness, tremor, and stiffness. TD symptoms include slow or jerky movements that one cannot control, often starting in the mouth with tongue rolling or chewing movements.
Temperature regulation: Impaired core body temperature regulation may occur; caution with strenuous exercise, heat exposure, and dehydration.
Second generation antipsychotics (SGAs) increase the risk of weight gain, high blood sugar, and high cholesterol. This is also known as metabolic syndrome.
Your health care provider may ask you for a blood sample to check your cholesterol, blood sugar, and hemoglobin A1c (a measure of blood sugar over time) while you take this medication.
- Information on healthy eating and adding exercise to decrease your chances of developing metabolic syndrome may be found at the following sites:
- http://www.helpguide.org/articles/healthy-eating/healthy-eating.htm
- http://www.helpguide.org/home-pages/exercise-fitness.htm
SGAs have been linked with higher risk of death, strokes, and transient ischemic attacks (TIAs) in elderly people with behavior problems due to dementia.
All antipsychotics have been associated with the risk of sudden cardiac death due to an arrhythmia (irregular heart beat). To minimize this risk, antipsychotic medications should be used in the smallest effective dose when the benefits outweigh the risks. Your doctor may order an EKG to monitor for irregular heartbeat.
Neuroleptic malignant syndrome is a rare, life threatening adverse effect of antipsychotics which occurs in <1% of patients.
Symptoms include confusion, fever, extreme muscle stiffness, and sweating. If any of these symptoms occur, contact your health care provider immediately.
All antipsychotics can cause sedation, dizziness, or orthostatic hypotension (a drop in blood pressure when standing up from sitting or lying down). These side effects may lead to falls which could cause bone fractures or other injuries. This risk is higher for people with conditions or other medications that could worsen these effects. If falls or any of these symptoms occur, contact your health care provider.
The U.S. Food and Drug Administration (FDA) is warning that compulsive or uncontrollable urges to gamble, binge eat, shop, and have sex have been reported with the use of aripiprazole (Abilify, Abilify Maintena, Aristada, Aristada Initio). These uncontrollable urges were reported to have stopped when the medicine was discontinued or the dose was reduced. These impulse-control problems are rare, but they may result in harm to the patient and others if not recognized.
Are There Any Risks For Taking Aripiprazole For Long Periods Of Time?
Tardive dyskinesia (TD) is a side effect that develops with prolonged use of antipsychotics. Medications such as aripiprazole have been shown to have a lower risk of TD compared to older antipsychotics, such as Haldol® (haloperidol). If you develop symptoms of TD, such as grimacing, sucking, and smacking of lips, or other movements that you cannot control, contact your health care provider immediately. All patients taking either first or second generation antipsychotics should have an Abnormal Involuntary Movement Scale (AIMS) completed regularly by their health care provider to monitor for TD.
Second generation antipsychotics (SGAs) increase the risk of diabetes, weight gain, high cholesterol, and high triglycerides. (See “Serious Side Effects” section for monitoring recommendations).
What Other Medications May Interact With Aripiprazole?
The following medications may increase the levels and effects of aripiprazole:
- The antibiotic clarithromycin (Biaxin®)
- Antidepressants, such as fluoxetine (Prozac®), paroxetine (Paxil®), and nefazodone
- Antifungals, such as fluconazole (Diflucan®), ketoconazole (Nizoral®), and itraconazole (Sporanox®)
- The antiarrhythmic agent quinidine
- HIV medications, such as the protease inhibitors indinavir (Crixivan®), ritonavir (Norvir®), saquinavir (Fortovase®, Invirase®), and lopinavir/ritonavir (Kaletra®)
The following medications may decrease the levels and effects of aripiprazole: carbamazepine (Tegretol®) and rifampin (Rifadin®).
How Long Does It Take For Aripiprazole To Work?
It is very important to tell your doctor how you feel things are going during the first few weeks after you start taking aripiprazole. It will probably take several weeks to see big enough changes in your symptoms to decide if aripiprazole is the right medication for you.
Antipsychotic treatment is generally needed lifelong for persons with schizophrenia. Your doctor can best discuss the duration of treatment you need based on your symptoms and illness.
- Hallucinations, disorganized thinking, and delusions may improve in the first 1-2 weeks
- Sometimes these symptoms do not completely go away
- Motivation and desire to be around other people can take at least 1-2 weeks to improve
- Symptoms continue to get better the longer you take aripiprazole
- It may take 2-3 months before you get the full benefit of aripiprazole
Summary of FDA Black Box Warnings
Increased mortality in elderly patients with dementia related psychosis
- Both first generation (typical) and second generation (atypical) antipsychotics are associated with an increased risk of mortality in elderly patients when used for dementia related psychosis.
- Although there were multiple causes of death in studies, most deaths appeared to be due to cardiovascular causes (e.g. sudden cardiac death) or infection (e.g., pneumonia).
- Antipsychotics are not indicated for the treatment of dementia-related psychosis.
Suicidal Thoughts or Actions in Children, Teens, and Young Adults
Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide.
- Patients treated with antidepressants may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in behavior, whether or not they are taking medications. This risk may persist until significant remission occurs.
- Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or health care professional.
- All patients being treated with this medication for depression should watch for and notify their health care provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.
Provided by
(November 2022)
©2022 The College of Psychiatric and Neurologic Pharmacists (CPNP) and the National Alliance on Mental Illness (NAMI). CPNP and NAMI make this document available under the Creative Commons Attribution-No Derivatives 4.0 International License. Last Updated: January 2016.
This information is being provided as a community outreach effort of the College of Psychiatric and Neurologic Pharmacists. This information is for educational and informational purposes only and is not medical advice. This information contains a summary of important points and is not an exhaustive review of information about the medication.
Always seek the advice of a physician or other qualified medical professional with any questions you may have regarding medications or medical conditions. Never delay seeking professional medical advice or disregard medical professional advice as a result of any information provided herein. The College of Psychiatric and Neurologic Pharmacists disclaims any and all liability alleged as a result of the information provided herein.
8 Answers inc. Side Effects, Dosage & Uses for Aripiprazole
Aripiprazole, sold under the brand name Abilify, is an oral and injectable medication used to treat mental disorders such as schizophrenia, Tourette’s, bipolar disorder, and in some cases, depression. Abilify is thought to restore the balance of naturally occurring chemicals within the brain to reduce symptoms such as hallucinations and improve concentration. In general, it can be used to help people with mental disorders more actively participate in everyday life.
The content on this page is provided for informational purposes only.
If you have any questions or concerns about your treatment, you should talk to your doctor, pharmacist, or healthcare professional. This is particularly important if you are taking multiple medications or have any existing medical conditions.
What is Abilify (aripiprazole) used for?
Abilify is used to treat the symptoms of mental or mood disorders (schizophrenia, bipolar disorder, depression, Tourette’s disorder, and irritability associated with autism spectrum disorder) but it does not cure the actual disease. It can be used alone or alongside other medications. Abilify is an antipsychotic drug, antimanic agent, making it a common prescription for those who suffer from manic episodes or hallucinations.
How Does Abilify Work?
It is not completely understood how aripiprazole, Abilify’s active ingredient, actually works. However, studies have suggested that the drug works by activating the serotonin and dopamine receptors in the brain which in turn stabilizes moods, behavior, and thinking.
Dopamine regulates the way we think and feel, and serotonin influences your mood and behavior. Many people suffering from mental conditions have too much or too little of one or both chemicals. By stabilizing the levels of these chemicals, Abilify is thought to improve thoughts, behaviors, and mood.
What are the side effects of Abilify (aripiprazole)?
Abilify is a second-generation psychotic, also known as an atypical antipsychotic. In comparison to first-generation psychotics, side effects are milder. However, Abilify can still cause side effects ranging from mild to severe. Mild side effects typically go away after a few days or weeks of consistent medication-taking, but if they persist or worsen you should speak with your doctor.
Mild Side Effects:
- Nausea
- Memory loss
- Headache
- Dizziness
- Cold-like symptoms
- Anxiety
- Hair Loss
- Libido Changes
- Insomnia
Severe Side Effects:
- Stroke – If you notice numbness or weakness on one side of your body, a feeling of confusion, or trouble walking, seek immediate medical attention.
- Neuroleptic malignant syndrome (NMS) – Symptoms include high fever, a rapid heartbeat, and stiff muscles. NMS is a medical emergency and you should seek immediate medical attention if you notice these symptoms.
- Changes in metabolism – This is usually marked by feeling unusually thirsty or hungry, feeling confused, and gaining weight.
- Feeling unusual urges – Urges do something you would not ordinarily do or to do something excessively, constitute an unusual urge. These can range from binge eating to sexual urges.
- Extrapyramidal disorder – This is a movement disorder that can cause symptoms such as tremors, trouble speaking , and anxiety.
If you experience any of these serious side effects you should speak with your doctor or seek immediate medical attention if it is an emergency.
In some rare cases, patients can experience allergic reactions. Seek emergency medical care if you experience any of the following symptoms after taking Abilify.
- Skin rash
- Wheezing
- Tightness in the throat or chest
- Difficulty talking or breathing
- Swelling of the face, lips, tongue, or throat
Does Abilify cause weight gain?
Oftentimes patients being treated for mental conditions such as bipolar disorder are used to weight gain as a potential side effect. For that reason, a common question from patients who are prescribed Abilify is “will I gain weight?” A potential side effect of Abilify and other atypical antipsychotics is weight gain. If you notice your weight increasing, speak with your healthcare provider about ways to best manage your weight.
How long does Abilify withdrawal last and what does it entail?
There are a variety of reasons why a person may stop taking Abilify and as with any other antipsychotic, it is possible to experience withdrawal. The limited research that has been conducted on this topic suggests that around 40% of people who stop taking antipsychotics will experience some form of withdrawal.
Symptoms may include:
- Nausea and vomiting
- Insomnia
- Restlessness
- Anxiety
- Panic attacks
- Dizziness
- Cold-like symptoms
- Muscle spasms or uncontrolled movements
If you’re experiencing these symptoms, you’re almost certainly wondering when you can expect them to end. Typically, the symptoms will reach a peak after approximately one week, and will decline gradually over time.
A safer way to stop taking Abilify is to gradually do so under the direction and care of your healthcare provider. He or she can help you slowly reduce your dose so that you are less likely to experience severe withdrawal symptoms.
How long does it take Abilify to work?
Due to the nature of Abilify and the severity of symptoms it may be used to treat, it isn’t uncommon to wonder how long it will take to be effective. Since everyone is different, there is no one definitive answer. It can start making a noticeable difference in just a couple days or it may take a few weeks.
However, most people will have felt the full effects of the medication within four to six weeks of beginning treatment. It is important not to stop taking Abilify just because you begin feeling better. Continue your dose as instructed by your healthcare provider to maintain the benefits.
How much does Abilify cost?
The price of Abilify will vary greatly depending on location and insurance coverage. However, the cash price of Abilify is $940.71 for 30 tablets of 2mg, 5mg, 10mg, or 15mg. The price for 30 20mg or 30mg tablets is $1,326.65. Regardless of the dosage, Abilify is typically taken once a day so these prices are for a one-month supply.
Can I combine Abilify and alcohol?
Typically, drinking is not recommended while taking Abilify, as alcohol can increase the effects of Abilify on the nervous system. This can lead to dizziness, drowsiness, and difficulty concentrating. It may also result in poor judgment and impaired thinking. Drinking alcohol can also have negative effects, depending on the medical condition you are taking Abilify to treat.
If you intend to drink while taking Abilify you should first speak with your doctor.
The content on this page is provided for informational purposes only. If you have any questions or concerns about your treatment, you should talk to your doctor, pharmacist, or healthcare professional. This is particularly important if you are taking multiple medications or have any existing medical conditions.
Trick your brain: how to overcome laziness and start working
Recent advances in neuropsychology will help everyone who is used to being lazy, but is looking for new ways of motivation
Early yesterday, no time today, late tomorrow. We are always waiting for the right moment to make a dream come true. Either there is no time and knowledge, then the circumstances are not the same. Famous people had similar problems.
Everyone got out as best they could. So, resentment and hatred for the Metallica group moved forward Dave Mustaine, the founder of the American metal band Megadeth, the French writer Victor Hugo cut his hair in an unsightly way to eliminate the desire to go out and finish the novel on time, and the composer Ludwig van Beethoven stimulated activity by pouring ice water. Nowadays, it is not necessary to resort to such radical methods. It is enough to analyze the latest achievements in the field of neuropsychology, adjust your behavior a little and enjoy the result.
Finished reading here
As we already know from the previous article, two opposing parts live in us. The representative of the ancient brain, let's call him Zhrulkin (he wants everything now), and the young brain - Rationalov (thinks about the future). Due to the fact that Rationalov consumes more energy and is less responsible for survival and procreation, Zhrulkin more often dominates us.
The usefulness of Zhrulkin has been proven by millions of years of incredible human vitality. He makes sure that we work less, eat more, and motivate us to have sex. There are exceptions, and a person from childhood can control Zhrulkin, but not everyone is so lucky. Therefore, most need various tricks in order to push it into the background. Consider the most effective ways.
Use your brain's weakness for unfinished business
Once you start, you won't be stopped. The brain gets to work. After all, unfinished business terribly annoys him. This was confirmed in his research by psychologist Kenneth McGraw. The subjects were given a puzzle and, when everything was almost ready, they were asked to finish. There was no rational point in continuing to complete the puzzle, but 90% of the participants remained to complete the work.
A similar effect occurs when reading an uninteresting book or watching a movie.
There is no point in continuing, but unconsciously I want to finish reading or watching it. To use the method for your own selfish purposes, it is enough to get off the ground, for example, by working in a group of like-minded people.
The action in progress effect will keep pushing you to work.
Change your mental attitude
A patient of the American psychiatrist Milton Erickson could not keep her weight at 60 kg. As soon as the cherished figure was reached, the girl returned to her usual 80 kg. Erickson warned that the treatment would be painful, and the patient agreed. He forced her to increase her total from 80 to 90 kg. The girl threw tantrums, sobbed, but gradually recovered to 90 kg.
And then, with incredible relief, she began to reduce it and quickly reached 60 kg.
The secret of success is to change the mental attitude from "lose weight - gain weight" to "gain - lose weight." The fear of overcoming this horror again allowed me to consolidate my success and not gain more weight. Many more are familiar with the problem of skipping workouts: today I will cancel the lesson, but next time I will go 100%. And the next day, do not go, giving yourself a new promise. The way out will be to change the attitude “I won’t go today - I’ll go tomorrow”, to “I won’t go today - I won’t go tomorrow”. Promise yourself that if you skip class today, you will forget about sports for two weeks. And it is more difficult to do it than to postpone it for tomorrow. So you get rid of the standard excuse and stop feeding yourself breakfast.
Make the first step as easy as possible
Getting started is often difficult because of how long it can take.
The brain draws scary pictures of a temporary apocalypse. Trembling with horror, we try to move this terrible moment as far as possible. An effective anti-apocalyptic solution would be to split the task into a number of small, not scary, and sometimes tasty ones. You don't have to do a thesis.
Plan to make a title page, table of contents, or introduction. It is best that the first step takes no more than 20 seconds. Thanks to the butterfly effect, small actions can lead to incredible results.
Build neural connections
The brain doesn't like doing new things. From his point of view, it can be unsafe and very energy-consuming. The new activity differs from the usual one in a smaller number of neural connections in the brain. And to develop new connections, you need to constantly practice.
The practice of visualization copes with this task very well: the brain does not care whether you are actually doing the work or just imagining how you are working on a new thing.
In both cases, new neuropaths will be built. The effectiveness of visualization was able to prove the Australian psychologist Alan Richardson, conducting research on basketball players.
Only by visualizing their training sessions with throwing the ball into the basket, the players were able to improve their results. The progress of the players who trained in the gym during the same time was not much better. If you do not have enough willpower to start the daily necessary actions, mentally imagine that you are doing this business, and most importantly, with pleasure. Only the necessary neural connections will be developed in at least 45 days, but with each repetition it will be easier and easier for you to act.
Train your willpower
Success in life depends on willpower. The research of professor of psychobiology Casey from Cornwell University clearly proves this. Casey offered marshmallows to the children, but with the condition that if you wait 15 minutes, you can get another sweet. Some of the children could not resist the temptation and ate marshmallows right away. After 40 years, the professor decided to find out the fate of the children and saw that those who passed the test and did not eat marshmallows turned out to be more efficient, moderate in nutrition and less susceptible to bad habits. But there is good news for the weak-willed: willpower can be trained.
You can follow the path of the physicist Nikola Tesla, who deliberately refused desserts in favor of others, thus developing willpower.
Or start meditating. After all, meditation suppresses the ancient impulsive brain, reducing stress, anxiety and fear. Meditation activates the frontal lobes responsible for willpower, improving attention, memory, concentration and creativity. Five to ten minutes of meditation a day is enough to develop self-control.
Fill up with hormone fuel
Hormones regulate metabolism and cellular activity, have a significant impact on performance. A cocktail of melatonin, dopamine, endorphin, serotonin and oxytocin will add strength and motivation to achieve outstanding results.
Melatonin strengthens the immune system, slows down the aging process, and is produced only at night, so good sleep is so important.
Dopamine is a hormone of pleasure, it affects motivation.
It is helped to produce pleasant memories, delicious food, and alcohol, but with devastating consequences.
Endorphin is a hormone of joy. Synthesis occurs under the influence of physical activity.
Serotonin is a hormone of good mood, produced under the influence of pleasant memories and sunlight.
Oxytocin reduces anxiety, and its synthesis is promoted by sex, massage and communication with friends.
The main thing to remember is that the performance depends on the quality of the fuel. Therefore, supply the body with first-class fuel.
These recommendations will be enough to move in the direction of your dreams.
After all, a modern person has at least a few opportunities a day to change his life, and the surrounding conditions are conducive to this. The main thing is to suppress the desire to radically change in one day, and introduce new practices gradually, without stress for the body. And according to the law of dialectics, quantity always turns into quality.
Therefore, 30 minutes of daily willpower will be enough to reach new heights in the field of health, relationships, finances, creativity and other areas of life. The point is small - to tear yourself off the couch and act.
- The secret life of the brain: the reasons why we are lazy
- Ladder of success. Why money doesn’t make us happy
- Constructor for oneself: how human emotions arise and what they depend on
The Amur region is stepping up work on creating the largest gas chemical cluster in the Far Eastern Federal District — Amurskaya Pravda
In the region, work is being intensified to create the largest gas chemical cluster in the Far East. The governor of the region, Vasily Orlov, gave an instruction about this the day before. “The center of the gas chemical complex is now the Svobodny ASEZ. Here, the construction of the largest Amur GPP in the country is in the active phase, in the near future a decision will be made to build another mega-plant - the Amur Gas Chemical Complex. Today, they form the main influx of investments in the region, thanks to which the necessary socio-economic and industrial infrastructure is being created,” said Lyudmila Starkova, Minister of Economic Development and Foreign Relations of the Amur Region.
However, according to the minister, after the launch of these facilities at full capacity, the volume of current investments is expected to decrease. “In order to fully use the existing infrastructure for the benefit of the development of the territory and create a new influx of investments in the future, we will reformat the work on creating a gas chemical cluster in the region.
In other words, the medium-term investment potential of the Amur region is being formed here now,” explained Lyudmila Starkova.
Photo: Press Service of the Government of the Amur Region
The ministry is working in this direction jointly with the Ministry for the Development of the Russian Far East, as well as with the federal and regional Investment Promotion Agency. As Pavel Puzanov, head of the Investment Promotion Agency of the Amur Region, notes, the development of gas chemical production in the world is now based on the cluster approach. This allows you to create several dozen interconnected industries and reduce operating costs. Cluster members are in close interaction, but do not compete with each other. Over time, the market begins to perceive the cluster as a single company, where you can immediately purchase a wide range of products.
- The raw material base of the gas chemical cluster in the Amur region will allow the production of a number of products that are in demand on the domestic and foreign markets.
Film and non-woven materials, pipes for various purposes, packaging, glues and adhesives (substances that connect materials with surface adhesion - Approx. AP), consumer goods - this is only a part of the production capabilities that the Amur Gas Chemical Cluster will have, - listed Pavel Puzanov.
Photo: Joint press center of the Amur GPP construction project
Today, the concept of a gas chemical cluster involves the participation of large regional, Russian and international investors at the initial stage. However, in the future, with the help of state support measures, small and medium-sized businesses can become full-fledged participants. This, in turn, will lead to the creation of new jobs and improve the welfare of the region as a whole.
The concept of a gas chemical cluster is planned to be considered at the next meeting of the Supervisory Board for the development of priority development areas in the Amur Region. It will take place at the end of February 2020.
The gas chemical cluster will provide investors with the opportunity to create new production facilities based on large-scale investment projects. They will complete construction in the coming years and start at full capacity. Cluster residents can be both large companies with a large amount of investment, as well as representatives of small and medium-sized businesses, the press service of the regional government notes.
Photo: Press Service of the Government of the Amur Region
Age category of materials: 18+
