Viibryd 10 mg reviews


Effectiveness, Ease of Use, and Satisfaction

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Most voted positive review

83 People found this comment helpful

I have been on most anti-depressants on the market but they stop working after a while. When my doctor gave me a sample packet with 10mg, 20mg and 40mg,I threw the paperwork away. I started on 10mg every morning for seven days. I THOUGHT I HAD DIED AND GONE TO HEAVEN. I felt like a new person. The same thing with the 20mg. My family and friends were amazed; however, I did talk a lot about not...

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Most voted negative review

28 People found this comment helpful

I am honestly starting my first day tomorrow and in hopes it will truely help my severe depression.

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Condition: Major Depressive Disorder

Overall rating 1.0

EffectivenessEase of UseSatisfaction

I was hopeful to have something more calming than my usual anxiety meds because I was getting really upset with my spouse more than ever before so my doctor had me try vibryd. Once I got to the 40mg after the first week or two, I thought I was going crazy. I cried and was scared and felt alone. I honestly thought I was losing it. I had insomnia, but the worst were nightmares and slight suicidal thoughts. I think this is a dangerous medication to take and I will never touch it again in my life.

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Condition: Major Depressive Disorder

Overall rating 1.0

EffectivenessEase of UseSatisfaction

My treatment was for anxiety and depression. I started on 20 mg and went up to 40mg after a couple of weeks. My anxiety got so bad that I had to go back to Paxil. The Viibryd did absolutely NOTHING for my anxiety or my depression. I'm still feeling awful. Only been back on the Paxil for a week but hoping that something improves because I am absolutely miserable.

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Condition: Major Depressive Disorder

Overall rating 3.0

EffectivenessEase of UseSatisfaction

I've dealt with depression in my teens. I have been diagnosed with major depressive disorder since 3 years ago. I maxed out on taking Effexor, Zoloft and Hydroxyzine..also take Gabapentin, and trazadone for sleep. Started Viibryd 1 week ago. So far I've had suicidal ideation ad am crying all the time from the minute I wake up up and throughout the day. I asked my doctor next week. TRYING TO HOLD OUT

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Condition: Other

Overall rating 5.0

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Generalized Anxiety Disorder-Have tried many different drugs. Celexa, Zoloft this by far is best and easiest on my body

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Condition: Other

Overall rating 1.3

EffectivenessEase of UseSatisfaction

I wish I would have read these reviews before I switched from Zoloft to Viibryd. I have been taking this for about 7 weeks now for anxiety. Started off on 40 mg of Viibryd right away. The first few weeks I felt dizzy with horrible stomach problems. Then on week 4 I forgot to refill my prescription (forgot my new dr was closed on Fridays). I could typically go 4 days without zoloft until I started to notice withdrawals. Not with Viibryd, withdrawals were noticeable the next day. I had to leave work a few times because I couldn't focus or stay awake. I have been at least an hour late to work because I physically can not wake up. My job is one of my favorite things in my life, so not being on time is completely out of the norm. I couldn't hold a conversation with coworkers or customers without feeling like a panic attack was coming on. My dreams have been so realistic and horrifying. These past few weekends, I have slept until 3 or 4 pm. Im a very active person so this is very unusual. I feel like my brain is going to explode and all I do is cry and have so much anger when I am awake. The best advice I can give- if you are feeling like this (crying, anger, rage, hurting yourself) is reach out to your biggest support person and cry and express your feelings. Today was the scariest episode i have had and im lucky enough to have an amazing, understanding daughter and husband. Do whatever calms you. Mine is a candle lit in my room watching hulu. Im slowly going to get off of this and switch back to zoloft. I do not recommend this drug but if you do try viibryd, please start off on the smallest dosage possible. Read More Read Less

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Condition: Major Depressive Disorder

Overall rating 2.0

EffectivenessEase of UseSatisfaction

I switched from long term prozac use to vibryd. I was on it for 2 weeks and almost ended up in ER. Ambulance called because of constant crying,rage and more. Very bad drug for me

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Condition: Major Depressive Disorder

Overall rating 2.3

EffectivenessEase of UseSatisfaction

TL;DR: viibryd gave me uncontrollable stomach aches and diarrhea after almost a year of use. Along with this, accidentally forgetting to take it would in turn disable me completely the next day, being unable to get out of bed due to extreme fatigue I’ve never felt before. Overall, it worked until It didn’t, and I almost want to cry about it, since it was my miracle drug for a good while. - I’m beyond devastated about the life altering side effects I started to develop 6+ months into viibryd. The drug had been the first one to ease my depressive symptoms and all of a sudden started to give me terrible belly issues. I would get stomach aches after every meal, but tried to change my diet to see if that would help. It didn’t, sadly. Went on vacation and was running to the bathroom multiple times after every meal with what I would describe as really bad pain and uncontrollable diarrhea. Weeks prior to this, I started to experience stomach aches after dinner everyday, but I thought my main issue was overeating (which it most definitely was, but viibryd was taking the stomach aches to another level). I will be going to my doctor asap to ween off this drug and depressingly start my drug hunt again. Read More Read Less

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Condition: Major Depressive Disorder

Overall rating 4.7

EffectivenessEase of UseSatisfaction

I thought I should add my experience with Viibryd cause it's definitely been a good one mostly. I started it after seeing my last psychiatrist, so about maybe first started when I was 21? I'm 25 just recently as well, I wouldn't still be taking a medicine if it didn't help me. I have multiple mental disorders & other health issues, but the after I started the Viibryd I was able to sleep better, do things, work, be productive, all instead of letting my depression & mental health crush me. I will say I don't think I had any stomach issues anyone said, & I take it IN THE MORNING, if your doctor is saying night, they're putting something that's basically giving you the go to move around & be awake in your nightmeds & it'll definitely mess you up. Also, the ONLY thing I've experienced side effects wise, was having night terrors & sleep paralysis if I miss a doze & take a nap during the day, I wouldn't advise it. & I experienced when they tried to change me from being on 40mg of Viibryd, major withdrawals while still being on 20mgs of it, it really helps alot more than most medicines I've been on, & I was Early Onset with Bipolar/Depression/Anxiety etc, so I was medicated by 7yrs old. I hope this helps someone in the future!Read More Read Less

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Condition: Major Depressive Disorder

Overall rating 4.7

EffectivenessEase of UseSatisfaction

I've tried and failed more than 15 antidepressants over the last 9 years since my depression diagnosis, and was feeling particularly discouraged after a bad time withdrawing from Effexor. My psychiatrist suggested I get genetic testing done to help narrow down what medications I might have fewer issues with, and Viibryd seemed like the next reasonable choice when we got my results back. I've been on Viibryd for about 7 months and it has honestly been night and day. I finally have the energy to do things again. I experience a bit of moodiness around the start of my periods but my depression is basically gone day to day. The one downside is a bit of stomach discomfort when I was first getting acclimated to it (as well as if I don't eat enough with my dose), but it's very manageable compared to the side effects I dealt with on other medications.Read More Read Less

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Condition: Major Depressive Disorder

Overall rating 4. 3

EffectivenessEase of UseSatisfaction

I'm a 57 year old terminally disabled veteran with an SMI diagnosis prolonged PTSD anxiety and depression this med has changed my life thank you

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Condition: Major Depressive Disorder

Overall rating 4.0

EffectivenessEase of UseSatisfaction

I think Viibryd is finally helping after about 2 months. So thankful! I’ve suffered from various levels of depression since my late teens. I’m almost 63. I’ve tried a lot of anti depressants. Didn’t work or couldn’t tolerate the side effects even after about 3 months, so stopped. However been on Wellbutrin 300 ER for about 25 year and it initially helped for years. About 10 years ago life/health issues began, took a turn for worse. Hypertension, elevated cholesterol, minor cardiac stuff. Carpal tunnel syndrome since corrected, osteoarthritis, and some other stuff. Never smoked, rarely pot years ago. Rarely drank. Had mild covid twice, vaccinated. Have mild Covid Long. Isolation due to Covid et cetera made depression worse. Initially 0.5 mg at night was great. FINALLY slept well. But after 2-3 nights I became hyper and couldn’t sleep. And had to take some thing to help me relax in order to sleep but eventually change the dose to morning. I’m not exactly an early riser but I do wake up a couple hours earlier than I would like to take the medication, 10 mg now, and then go back to sleep for an hour or two. I’m still sleeping really well. I feel it’s helping more by taking it in the morning. I haven’t gained weight from it but I am doing some exercise, always have. I don’t have much of an appetite during the day at all and 9pm…. So even though it’s not healthy I probably get most of my calories before I go to bed and probably just a little bit fewer than if I had an appetite during the day. My hope is it continues to work. I am beginning to feel that I need a an increase in the dosage. I’m assuming my MD will increase the dosage when I see her at the end of this monthRead More Read Less

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Condition: Major Depressive Disorder

Overall rating 2.7

EffectivenessEase of UseSatisfaction

Only on 4th day of starter pack and immediately the 1st day I have been running to the bathroom with diarrhea everyday. No appetite. Although after the 1st day I felt better a little lighter in the head without all the anxiety and voices horrible headaches. I would rather be be depressed and crying in the shower than on the toilet even after not eating anything all day.

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Condition: Major Depressive Disorder

Overall rating 1.0

EffectivenessEase of UseSatisfaction

I started taking this medication on March 23 my stomach started hurting on April 6, I told my Dr on numerous times that I could not take this medication. He kept saying this is good medication you have to get use to it. I suffered with pain in the top of my stomach, no appetite, lost weight 5lbs, felt tired, no energy, etc. still my Dr wanted me to take it at night. I could not it another night. It took two days for it to be out of my system, my pain stopped, my appetite returned, my energy was back. I was checking in at my Dr office and a lady was on the phone stating she started Viibryd the night before and she was in the emergency room the next day. RUN FROM THIS DRUGRead More Read Less

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Condition: Major Depressive Disorder

Overall rating 4.7

EffectivenessEase of UseSatisfaction

I have my life back! I have suffered from Depression since I was a teenager, high anxiety, panic attacks, OCD. Anti-depressant prescribing has always been a crap shoot for psychiatrists, try this one try that one, until we find the one that works, problem is it can take 6-13 weeks before the real effects are seen. Who wants to spend that much time when they are suffering, just to start all over again? I was on Zoloft for over ten years, it did help with the panic attacks and social anxiety, but the sexual side effects were too much for me. No libido and delayed ejaculation, if at all, no thank you. I had a DNA test and found that only 3 antidepressants were compatible with my biochemistry and Zoloft was not one of them. I decided to go with Viibryd because of its novel mode of action (Both Serotonergic Agonist and SSRI). About a year ago I tapered off the Zoloft and was antidepressant free for almost a full year. The depression came back with a vengeance. I tapered up on Viibryd, 2 weeks at 10 mg and then 20 mg. I have now been using it for 2 months with little side effects. I have a lust for life again! I am out of the house, no longer bed bound! One of the side effects is talkativeness, this was especially true for me if I had some alcoholic drinks. One should stay away from alcohol while on antidepressants anyway so I have stopped. My recommendation for those still suffering, ask your doctor about the DNA tests. It removes the guesswork of which drugs to try first. From a quick look at the numbers in these reviews, it looks like people either hate or love this drug. For me it has been an easy transition since I did not have any other antidepressants in my system. I wonder if others were seeing side effects of coming off their previous antidepressant when switching to Viibryd and then blaming Viibryd for those feelings? Every case is different and with antidepressants less is more, so be gentle on yourself and patient. Make sure you have a support system bigger than just a drug, the drug can only meet our disease halfway, group therapy is highly recommended. The only thing different about this drug is that it must be eaten with food, a high fat content meal is best, I don't think it needs to be a big meal, but without food less than half the drug is absorbed so it won't be as effective. I usually have Full Fat yogurt in the morning, I am not a morning person and I don't like to have a big breakfast, so this has been working for me. This is the first drug that I can truly say I feel a difference when I take it, and the difference for me has been wonderful! Read More Read Less

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Condition: Major Depressive Disorder

Overall rating 2.7

EffectivenessEase of UseSatisfaction

GI Bleeding. Not good for I have platelets less than 50,000 Constant diarrhea nausea. Stops working. In creases blood pressure on me. I have heart desease. Sleep paralysis. Insomnia. Nightmares.

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Condition: Major Depressive Disorder

Overall rating 5.0

EffectivenessEase of UseSatisfaction

I have tried zoloft which made me very sick i almost got into a car accident because of how dizzy i was, i tried lexapro who made me worst than zoloft and finally got into viibryd, it took a week to get the fully effect of the pill and made me a different person. I am taking right now 5mg which is a very low dosage but since i am very sensitive to medications, it was the right choice for me. I came back to life, i started doing things i couldnt like simple things as taking shower!...i feel different!...please give it time to work!....also, take it at the same time everyday and take it in the morning because it can give you nightmares!!!...the side effects are very mild!!!!!!...Read More Read Less

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Condition: Major Depressive Disorder

Overall rating 2.0

EffectivenessEase of UseSatisfaction

Viibryd is not for me. I titrated off Lexapro, which I had been on for 5 years, because it just kind of pooped out on me at the highest dose. My doctor had me start on Viibryd slowly, starting with 5mg, then 10mg, then 20mg, I was on it for about 6 weeks total, and I only felt worse day by day. I didn't have any gastro side effects, but I did have intense, vivid dreams that would hold influence over my whole day. I felt disconnected from everyone and everything in my life, distracted by anxiety and suicidal ideation. I felt hopeless, had excess energy that only fed my anxiety, and struggled to get out of bed every morning. I tried to stick with it, thinking that these were side effects I needed to push thought, but suicidal thoughts are NOT tolerable effects and you should contact your dr. immediately if they begin. My psychiatrist pulled me off and started me on another drug. Read More Read Less

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Condition: Major Depressive Disorder

Overall rating 4. 7

EffectivenessEase of UseSatisfaction

I've been taking this nearly a year and I've seen a fantastic improvement in my mood, especially during winter months when SAD makes things worse. Initially, I had a strong reaction to this medication but I stuck through it and after about 3-4 weeks, the side effects disappeared. This is compared to Wellbutrin that gave me awful initial side effects and Celexa that was milder. I had to discontinue Wellbutrin shortly after starting and I was on Celexa for over two years and stopped with the approval of my doctor and therapist. I hope to Viibryd to work through some issues and get to a healthier place. The side effects of this drug long term are far less severe or non existent compared to Celexa that had some persistent side effects. I would recommend it.Read More Read Less

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Condition: Major Depressive Disorder

Overall rating 1.0

EffectivenessEase of UseSatisfaction

I don’t understand how this is approved for use as an antidepressant. I’ve been on various antidepressants for half my life and I have never experienced the absolute horror of side effects that I did with Viibryd. Not only did I have the absolute worst insomnia, in my sleepless nights I had uncontrollable crying episodes and impulses to hurt myself. It was like I had no control over my body and it was horrifying. Do not take this medication.

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Condition: Other

Overall rating 3. 7

EffectivenessEase of UseSatisfaction

I switched from 40 mg Paxil to 40 mg Viibyrd using the proper titration schedule. The sexual side effects from Paxil disappeared week 2. Viibyrd is working just as well as Paxil for my PTSD and anxiety. However, I notice that Viibyrd is metabolized very quickly and absolutely must be taken after a large breakfast to carry me through the day. I have contacted the company that produces Viibyrd and asked if an XR or CR version was in development. I also suggested a coated version to survive the stomach environment better. If you are having the same same issue, please reach out to them via phone or e-mailRead More Read Less

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Viibryd (Vilazodone) Reviews | Everyday Health

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5 Stars

Posted 3 months ago (7/4/2022) 5

Rated for Depression Report

I have found it to be a wonderful drug. I would recommend not posting that you don’t think people should take it. Everyone reacts differently. I’ve had no side effects.

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1 Stars

Posted 4 months ago (6/25/2022) 1

Rated for Depression Report

Terrible side effects including feelings of being shocked, hallucinations, loss of balance. It has a short half-life and so must be taken at exactly the same time daily. It was helpful at first but now is having the reverse effect and causing lethargy, depression and anxiety. Very difficult to get off of it since it has a severe effect on my well being. My general practitioner made a huge mistake prescribing this and keeping me on it. My current psychiatrist is working very hard to get me off of it.

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4 Stars

Posted 4 months ago (6/19/2022) 4

Rated for Depression Report

I improved a great deal after 2 months. I was taking samples. Then when prescribed, after great results, my insurance company refused to pay for it. I have taken various antidepressants since 1982. This one was great for me but I can't get insurance for it. I have been on most antidepressants so I don't know why they won't cover it. I am back to my usual depressed state---no interest in doing anything. I used to love exercise---now no interest in exercise, being outdoors, sex, etc. Just BLAH and flat affect. It would have been wonderful to take this medication as prescribed to give me a better quality of life----damn insurance companies run by people in offices looking only at the dollar signs and not caring about the quality of people's lives.

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2 Stars

Posted 5 months ago (5/27/2022) 2

Rated for Depression Report

NOT working for me. Dr started me so slowly and its taken 3 months to get to 35mg. My depression is flat and my anxiety and panic is not under control and is even worse.I feel like Im taking a placebo. In fact its gotten so bad Im becoming agoraphobic. Seeing a new dr tomo and now have to figure out a whole other direction. You KNOW how hard it is switching meds to find the right one. I dread it, but this anxiety, panic and depression isn't responding to Viibryd. Oh, yes it is very toxic to your bowels as well. Not a happy camper writing this review. Back to square one.

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1 Stars

Posted 5 months ago (5/25/2022) 1

Rated for Depression Report

Constant nausea, ridiculous diarrhea, chronic lingering headaches, hot flashes any time I experienced any emotion (I’m only 31) heart racing, hands trembling, dizziness, loss of memory and oh my god the nightmares are so beyond horrible and I mean horrible. Stay away from this drug, I took it for months and these side effects never stopped. Worst drug I’ve ever taken.

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1 Stars

Posted 6 months ago (4/13/2022) 1

Rated for Depression Report

$1000/month with insurance... No thanks

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5 Stars

Posted 8 months ago (2/24/2022) 5

Rated for Depression Report

I've been taking this nearly a year and I've seen a fantastic improvement in my mood, especially during winter months when SAD makes things worse. Initially, I had a strong reaction to this medication but I stuck through it and after about 3-4 weeks, the side effects disappeared. This is compared to Wellbutrin that gave me awful initial side effects and Celexa that was milder. I had to discontinue Wellbutrin shortly after starting and I was on Celexa for over two years and stopped with the approval of my doctor and therapist. I hope to Viibryd to work through some issues and get to a healthier place. The side effects of this drug long term are far less severe or non existent compared to Celexa that had some persistent side effects. I would recommend it.

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1 Stars

Posted 9 months ago (1/11/2022) 1

Rated for Depression Report

Tried for eight weeks. Wouldn't recommend. Night sweats, nausea with vomiting, gi upset, the sexual dysfunction wasn't any different from other SSRIs. Read an article saying Viibryd failed 5 of 7 trails where it was no better than placebo and thought, wtf am I taking? Going to take a break from prescriptions and give st John's wort a try. Tired of depression. Good luck out there.

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1 Stars

Posted 12 months ago (10/6/2021) 1

Rated for Depression Report

So far, I am seeing that the people who like this drug are new users. I was all about it at first too. Now after 8 months, things are bad. Primarily, majorly depressed with all associated symptoms. I've also started up again with OCD and anxiety. If you have just started Viibryd and like it, be vigilant. The positive effects may diminish.

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4 Stars

Posted 17 months ago (5/11/2021) 4

Rated for Depression Report

Tried Lexapro, Wellbutrin, and one other that I can't recall the name of. Just being on 10mg for two weeks has revolutionized my life. The fog that hazed my vision has lifted, I feel more present in my surroundings and the people around me. My mood swings and horrific temper have disappeared almost over night. I had some diarrhea, passed a lot of gas and insomnia, but those have subsided. Haven't agreed to up the dose, yet, as 10mg has made huge strides for me. My depression and anxiety have nearly vanished almost over night, and the headaches and fogginess in the mornings have, as well. Would recommend if the other staples Haven't done you well (the ones i tried before made me crazier).

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1 Stars

Posted 18 months ago (4/17/2021) 1

Rated for Depression Report

Chest palpatines happened when sleeping. The anxiety and nervousness crept up daily. I was sorting laundry and had a panic attack. My chest felt like I was jumping off a cliff. I was so tried after such a severe attack, it left me worn out in a sweat. I couldn't sleep, and then I started to hallucinate. Looking at a nail in the wall, it would zoom in closer and closer every time I closed my eyes. Started vomiting and couldn't even hold water down. I was pacing my apartment, felt twitchy and dirty so I took a shower. Felt extremely out of place and uneasy. I then decided to go to the park, but felt so helpless and didn't see the meaning to life when watching parents cheer their kids playing baseball. I went back to my apartment and had the biggest crying fit I've ever had. I never felt that feeling of such despair and sadness. After this vomitting got worse, couldn't hold down water. I remember it felt like my brain was scrambled. 2 ER Hospital visits, 1 ambulance, 1 health clinic, and a verbal confrontation with a cab driver over the course of 48 hours. It was walking nightmare on this drug. Never again

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5 Stars

Posted 18 months ago (4/9/2021) 5

Rated for Depression Report

After years of trying different antidepressants, viibryd was the one I was waiting for. I feel present in the world, lost weight, and have no sexual side effects. I feel great after 6 month. I feel so lucky to have found this med. keep trying until you find the right medication for you.

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1 Stars

Posted 18 months ago (4/8/2021) 1

Rated for Depression Report

This is definitely not for me. I suffer with depression and anxiety. I was on Wellbutrin for almost 2 years but my anxiety was getting worse. I was taken off Wellbutrin and I started taking viibryd the middle of February 2021 at 10mg for about 2 weeks and felt really good but I could tell it wasn't enough so I started taking 20mg and that's when all the side affects started. I started having shock waves start at my chest and roll out my body, so bad I would twitch hard. Then one night I had a nose bleed and I haven't had one of those in over 20 years. My blood pressure was all over the place which I never had issues with before. I also started having inflammation in my gums and canker sores. Bad dreams almost every night and anxiety started to get worse and I just had no care for anything anymore. I wish this worked for me but it just didn't.

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5 Stars

Posted 19 months ago (3/24/2021) 5

Rated for Depression Report

This gave me the push I needed to get out of my funk !!! Everyone needs a little push every now and then this is what did it for me. I would recommend trying if your looking around. Just hang in there I know it sucks right now but time is the ultimate healer!!

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2 Stars

Posted 19 months ago (3/18/2021) 2

Rated for Depression Report

I was transitioned into Viibryd in 2011. It was wonderful. I had been on SSRI's for a total of 23 years. Even though the reason I went on them was long gone. The Profession kept me on SSRI's. Recently I went off them with the help of my MD. We took the long route of 6 weeks. Unfortunately, 6 weeks later I'm still experiencing long term discontinuation syndrome. Its now been a 12 week process and I'm still experiencing Anger, and cardiac palpitations.

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5 Stars

Posted 20 months ago (2/23/2021) 5

Rated for Depression Report

I’ve had this rx for 6 months and finally had enough and decided to take it. I was very concerned about the side effects, but I had some brain fog and a slight headache so I now take it at night. Viibryd has gotten me thru a tough spell, I would normally from 0-60 when it comes to health concerns and rush to the ER, viibryd has calmed me down and made me think rationally. My doc prescribed me this especially because it was said to not cause weight gain. So far, so good. Good luck to everyone.

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5 Stars

Posted 20 months ago (2/19/2021) 5

Rated for Depression Report

Everyone is different, but this was my savior after years of trying different SSRIs. I also take wellbutrin and visteril- good mix. I had such horrible anxiety and depression, I would just cry out of nowhere and couldn't help it- my body was broken. I feel human and can think straight, that is all I wanted for years. Viibryd has been. Godsend for me.

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2 Stars

Posted 20 months ago (2/15/2021) 2

Rated for Depression Report

My doctor didn’t tell me to go up in dosage so I’ve been on 10mg for 3 weeks. I’m going to try 20mg this week but I think I’ll most likely stop it all together after. The first night I took it I woke up having a panic attack, so I decided to take it in the morning from then on. No issues like that again fortunately. I started using ashwaganda before I started this and I was finally getting great sleep, falling asleep earlier, and my anxiety had gotten SO much better. Now I wake up every night at 3am and I’m up for several hours until I can fall back asleep. I feel very apathetic and unmotivated. I’m about to move and I should be excited or nervous and I just feel like “whatever.” And that’s definitely not me. :/ Like I said, I’m going to TRY 20mg for a few days but I’m sure it will suck and I’ll officially know it’s the meds and not me. I’m ready to have decent sleep again.

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1 Stars

Posted 20 months ago (1/30/2021) 1

Rated for Depression Report

I have never experienced so many side effects. . I cannot wait to have this medicine out of my body.

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2 Stars

Posted 21 months ago (1/21/2021) 2

Rated for Depression Report

I was taking 10 mg a day for depression for three weeks. My depression got marginally better, but I got really severe insomnia. I was always a light sleeper, and was waking through the night. But on Viibryd I simply can't fall asleep without a good dose of strong sleeping pills! Stopping it immediately.

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2 Stars

Posted 21 months ago (1/20/2021) 2

Rated for Depression Report

I’ve been on this for 2 years now at 20mg. At first it was nice, but it caused me to have so much water retention. Gained 40 lbs and keep going up despite healthy diet and exercise!!! Also, it causes me to have muscle twitches throughout my body. On eyelids, hands, legs etc. I am asking my Dr. to switch me.... I’ve had enough of this water weight! I feel like a walking water balloon

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5 Stars

Posted 21 months ago (1/18/2021) 5

Rated for Depression Report

This drug has really helped me. It has been 3 months now on 40mg and I feel like a normal person for once. The only negative thing is that the first 4-6 weeks are tough due to the side effects, insomnia and dizziness but now I have almost zero side effects with the only one being mild nausea if I don’t eat enough before taking it. I sleep 8 hours and feel well rested. My anxiety has reduced and my OCD has almost gone away. If you can get through the side effects in the beginning I highly recommend this.

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5 Stars

Posted 21 months ago (1/3/2021) 5

Rated for Depression Report

This medication saved my life. I’ve been prescribed it for 12 months now. Initially, I dealt with (more) vivid dreaming, which were nightmares in my case. It tore my stomach up if I was more than an hour late on taking it. I opted at taking it at lunch time so I knew I would have enough in my stomach. I’m on the patient assistance program, and had changed providers so recently was without Viibryd for 4 months... It took about 2-3 months to get back to a severely unhealthy state again, but I lost the ability to function. After about 10 days back on the medication, I am relived from all of what I had been experience in the lapse of the medication. I have my life back! I haven’t experienced any negative side effects since I have been taking it this time. Perhaps the nightmares subsided with therapy work. Viibryd is the ONLY thing that has ever worked for me.

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2 Stars

Posted 22 months ago (12/23/2020) 2

Rated for Depression Report

Worked for anxiety, but unfortunately it caused severe dizziness with a few falls. Also caused premature ventricular contractions and bradycardia. Discontinued after 2 weeks.

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2 Stars

Posted 22 months ago (12/22/2020) 2

Rated for Depression Report

Terrible, debilitating nausea and vomiting, bloating, disturbed sleep. I've quit this med twice to take other meds that have nausea side effects bc if i take them both I will throw up all day. With vibriid, no matter when i take it, how many mg, with or without food, I will throw up. Its terrible and depressing, of the meds I feel almost the same except i get to keep my breakfast. Sexual side effects are abt the same for me, taking the drug at night makes me toss and turn and sweat throughout the night. When i do manage to swallow and proccess the drug I feel restless and occasionally manic, I am already on a stimulant for ADHD so viibrid on top of that is not great. I've noticed a decrease in general motivation and in increase in brainfog and lack of awareness. Would not reccomend even as a last resort! Plan to switch asap if reweaning doesn't work, getting tired of vomiting every day.

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5 Stars

Posted 23 months ago (11/15/2020) 5

Rated for Depression Report

I don’t respond to other antidepressants. They make me gain weight and don’t work for depression or anxiety. For me, Viibryd was different. It was the first and only thing I’ve ever taken that helped me get back to feeling like me again. I do t mean to sound like a commercial or overly-sentimental, but it really did happen that way. I’m a different person because of Viibryd. I was at my wit’s end not being able to manage my emotions. Viibryd cleared my thinking and helped me to cope with everyday life again. Couldn’t be more pleased.

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3 Stars

Posted 24 months ago (10/20/2020) 3

Rated for Depression Report

Took for GAD. Worked fairly well for my anxiety, but caused significant dizziness which didn’t resolve and for some reason premature ventricular contractions and bradycardia. These side effects resolved after stopping the drug.

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5 Stars

Posted 24 months ago (10/16/2020) 5

Rated for Depression Report

Viibryd quite literally saved my life. I have been treated for anxiety/depression for 30 years, since my late teens. I have been on all of the traditional SSRIs at one point or another, and none have had lasting effects. I have been on 40mg Viibryd for nearly 10 years now. My depression is controlled, and I am focused. I have been able to go back to school, and am about to graduate from veterinary school. The only adverse effect that I experienced was when I was trying to take it at night, before bed. I had lucid night terrors that I was unable to wake from. Taking the medication in the morning has eliminated this. If I forget a dose, I am shaky, itchy, and experiencing withdrawal symptoms by the evening.

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3 Stars

Posted 24 months ago (10/16/2020) 3

Rated for Depression Report

This is about a 4 week report, so much remains to be seen. Initially I had severe diarrhea and headaches. Diarrhea cleared up in under a week, headaches a bit longer. Am experiencing considerable dizziness and have to be quite careful with movements. However, it is having a positive effect on mood. Also, while some report a kind of brain fog, l feel quite alert - BUT with a tendency to feel sleepy during the day. ( yes, it seems contradictory). Not quite sure how this is going to affect night sleep yet. The sleepiness is a puzzler. Who can say if this is good for someone else? It obviously has a palpable effect on the body ( brain included) and with side effects that can be distracting or at least temporarily, somewhat disabling. E.g., if you had to do a lot of physical work or operate complicated machinery, this would be a big problem. Pretty obviously as well, there's no way anyone should drink any alcohol with this effect. I am willing to stick to long trial because I feel definitely better mood-wise, and can afford the time to accommodate - and see if the vertigo goes away. [ If it doesn't - don't know what I will do]

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1 Stars

Posted 26 months ago (8/7/2020) 1

Rated for Depression Report

I have been on SSRI’s for 7 years and this was by far the worst one due to side effects. The first week at 10mg was fine, I experienced manageable diarrhea but also felt unfocused and had brain fog. One full day into taking the 20mg pill and I had a full on panic attack where I had to pull over on a highway. I had a very fast heartbeat, sweating, and I felt like breathing was a manual action. I decided to tough it out for a few more days blaming the panic attack on stress and dehydration. I’m three days post panic attack and have the worst migraine and I NEVER even get headaches. I’m going to stop cold turkey even though it is not recommended because I am miserable. Taking Viibryd has scarred me on SSRI’s and I will be resorting to a healthier diet and more exercise for my anxiety. Do yourself a favor and never take this medication.

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5 Stars

Posted 27 months ago (7/22/2020) 5

Rated for Depression Report

Balanced my moods and brought me back to life

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5 Stars

Posted 27 months ago (7/20/2020) 5

Rated for Depression Report

This drug changed my life for the better. I have struggled with depression for years, and taken many other SSRIs. My biggest symptom of depression is hypersomnia. I would sleep and sleep and sleep and sleeeep. I would take naps daily. I’ve been on Viibryd over 7 months now, and have barely ever taken any naps. I can sleep 8 hours and feel rested. I can not recommend this drug enough. Absolute life changer. The only side effect I get is that I sometimes wake up in the middle of the night and it’s hard to go back to sleep. It doesn’t happen too often though.

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5 Stars

Posted 28 months ago (6/11/2020) 5

Rated for Depression Report

I switched from Trintellix as I don't feel sad and depressed but rather very angry and out of control with life. 10mg for 7 days then to 20 mg-had a little insomnia for about a week-wasn't tired and just kept waking up constantly but never felt tired during the day. I have an incredible amount of energy and feel like I now have a filter when something upsets me I can take a minute and decide if it's really worth getting angry about. I didn't experience any stomach issues which was great as I already have IBS so even if I didn't, I'm used to it. Of course everyone is different but I highly recommend talking to your doctor if you have more issues of anger versus sadness. Best of luck to eveyone.

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5 Stars

Posted 29 months ago (5/21/2020) 5

Rated for Depression Report

On 20 mg of Viibryd for depression. Working very well so far. Happy feelings/mood and reduced nightmares. Was on Wellbutrin for years but had to stop due to headaches getting worse. Having significant diarrhea and popping awake during the night. Only on Viibryd for 3 weeks so far though. Works so well on depression that I’m willing to stay with it and hope the side effects fade.

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5 Stars

Posted 29 months ago (5/11/2020) 5

Rated for Depression Report

I started taking Viibryd on April 20, 2020 at 10mg and upped to 20mg the following week. I felt better within a couple of days. I'm writing a review because I had been prescribed this medication last June and was scared by some of the reviews. It worked very well for me - with mild/tolerable side effects that were short lived. The benefits far outweigh the mild side effects. I would say you need to try it for yourself and not put too much weight in the reviews. EVERYONE is different. Trust your doctor if he suggests it and speak to him about any issues you may have. I wish I had started last June now.

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Viibryd Starter Pack - instructions for use, dosage, composition, analogues, side effects / Pillintrip

Page reviewed by pharmacist Svetlana Olegovna Kovalenko original. Do not use this information for any medical prescription or manipulation under any circumstances. Be sure to read the original instructions for the medicine from the package. This description may contain numerous errors due to automatic translation! Keep this in mind and do not use this description!

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Viibryd Starter Pack

Therapeutic indications

Description Therapeutic indications Viibryd Starter Pack is an automatic translation from the original language. Do not use this information for any medical prescription or manipulation under any circumstances. Be sure to read the original instructions for the medicine from the package. This description may contain numerous errors due to automatic translation! Keep this in mind and do not use this description!

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Indication is a term used to list a condition or symptom or illness for which a drug is prescribed or used by a patient. For example, acetaminophen or paracetamol is used by a patient for a fever, or a doctor prescribes it for a headache or body aches. Currently, fever, headache and body aches are signs of paracetamol. The patient must be aware of the indications of the drugs used for general conditions because they can be taken over the counter in the sense of a pharmacy without a doctor's prescription.

Viibryd Starter Pack® is indicated for the treatment of major depressive disorders (MDD).

DOSAGE AND ADMINISTRATION

Dosage for the treatment of major depressive disorders

The recommended target dose for Viibryd Starter Pack is 20 to 40 mg orally once a day with food. To reach your target dose, titrate Viibryd Starter Pack as follows:

  • Start with an initial dose of 10 mg once daily with food for 7 days
  • Then increase to 20 mg once daily with meals.
  • Dose may be increased to 40 mg once daily with meals with a minimum of 7 days between dose increases.

If a dose is missed, it should be taken as soon as the patient remembers. If it is almost time for the next dose, the patient should skip the missed dose and take the next dose at the usual time. Two doses should not be taken at the same time.

Bipolar screen before Viibryd 9 Starter Pack0033

Before starting treatment with Viibryd Starter Pack or another antidepressant, evaluate patients for a personal or family history of bipolar disorder, mania, or hypomania.

Switching to a monoamine oxidase inhibitor antidepressant

At least 14 days must elapse between stopping the monoamine oxidase inhibitor (MAOI) antidepressant and starting the Viibryd starter pack. In addition, after stopping Viibryd Starter Pack, at least 14 days must elapse before starting an MAOI antidepressant.

Dosage adjustment with CYP3A4 inhibitors or inducers
Patients receiving concomitant CYP3A4 inhibitors

If a strong CYP3A4 inhibitor (e.g., itraconazole, clarithromycin, voriconazole) is co-administered, the dose of Viibryd Starter Pack should not exceed 20 mg once day. The baseline dose of Viibryd Starter Pack may be restarted after the CYP3A4 inhibitor has been discontinued.

Patients receiving concomitant CYP3A4 inducers

Based on clinical response, consider doubling the dose of Viibryd Starter Pack, to a maximum of 80 mg once daily, for 1 to 2 weeks in patients taking strong CYP3A4 inducers (eg., carbamazepine, phenytoin, rifampin ) more than 14 days. If CYP3A4 inducers are discontinued, gradually decrease the dosage of Viibryd Starter Pack to its original level over 1 to 2 weeks.

Stopping treatment with Viibryd Starter Pack

Adverse reactions may occur when stopping Viibryd Starter Pack. Gradual dosage reduction rather than abrupt discontinuation is recommended whenever possible. The Viibryd starter pack should be reduced from 40 mg once daily to 20 mg once daily for 4 days and then 10 mg once daily for 3 days. Patients taking Viibryd Starter Pack 20 mg once daily should be tapered to 10 mg once daily for 7 days.

Viibryd Starter Pack (Viibryd Starter Pack) is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs).

Viibryd Starter Pack is used to treat major depressive disorders (MDD).

Viibryd Starter Pack may also be used for purposes not listed in this medication guide.

Dosage and Administration

Description Dosage and Administration Viibryd Starter Pack is an automatic translation from the original language. Do not use this information for any medical prescription or manipulation under any circumstances. Be sure to read the original instructions for the medicine from the package. This description may contain numerous errors due to automatic translation! Keep this in mind and do not use this description!

more. ..

2.1 Dosage for Major Depressive Disorders

The recommended target dose for Viibryd Starter Pack is 20 to 40 mg orally once a day with food. Titrate Viibryd Starter Pack as follows to reach target dose:

  • Start with an initial dose of 10 mg once daily with food for 7 days
  • Then increase to 20 mg once daily with food.
  • Dose may be increased to 40 mg once daily with meals with a minimum of 7 days between dose increases.

If a dose is missed, it should be taken as soon as the patient remembers. If it is almost time for the next dose, the patient should skip the missed dose and take the next dose at the usual time. Two doses should not be taken at the same time.

2.2 Screen for Bipolar Disorder Before Starting Viibryd Starter Pack

Before starting treatment with Viibryd Starter Pack or other antidepressant, evaluate patients for a personal or family history of bipolar disorder, mania, or hypomania.

2.

3 Switching to or from a monoamine oxidase inhibitor antidepressant

At least 14 days must elapse between stopping a monoamine oxidase inhibitor (MAOI) antidepressant and starting the Viibryd starter pack. In addition, after stopping Viibryd Starter Pack, at least 14 days must elapse before starting an MAOI antidepressant.

2.4 Dose adjustments with CYP3A4 inhibitors or inducers

Patients receiving concomitant CYP3A4 inhibitors:

When a strong CYP3A4 inhibitor (eg, itraconazole, clarithromycin, voriconazole) is co-administered, the dose of Viibryd Starter Pack should not exceed 20 mg once daily. The baseline dose of Viibryd Starter Pack may be restarted after the CYP3A4 inhibitor has been discontinued.

Patients receiving concomitant CYP3A4 inducers:

Based on clinical response, consider increasing the dose of Viibryd Starter Pack by a factor of 2, up to a maximum of 80 mg once daily, for 1 to 2 weeks in patients taking strong CYP3A4 inducers ( eg. , carbamazepine, phenytoin, rifampin) for more than 14 days. If CYP3A4 inducers are discontinued, gradually decrease the dosage of Viibryd Starter Pack to its original level over 1 to 2 weeks.

2.5 Stopping treatment with Viibryd Starter Pack

Adverse reactions may occur when stopping Viibryd Starter Pack. Gradual dosage reduction rather than abrupt discontinuation is recommended whenever possible. The Viibryd starter pack should be reduced from 40 mg once daily to 20 mg once daily for 4 days and then 10 mg once daily for 3 days. Patients taking Viibryd Starter Pack 20 mg once daily should be tapered to 10 mg once daily for 7 days.

Contraindications

Description Contraindications Viibryd Starter Pack is an automatic translation from the original language. Do not use this information for any medical prescription or manipulation under any circumstances. Be sure to read the original instructions for the medicine from the package. This description may contain numerous errors due to automatic translation! Keep this in mind and do not use this description!

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What is the most important information I should know about the Viibryd Starter Pack?

Do not use Viibryd Starter Pack if you have used an MAO inhibitor such as furazolidone (Furoxon), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepril, Emsam, Zelapar) or tranylcypromine (Parnate) in last 1. Dangerous drug interactions can occur, resulting in serious side effects.

Before taking Viibryd Starter Pack, tell your doctor if you have liver or kidney disease, a bleeding or bleeding disorder, seizures, bipolar disorder, low blood sodium, or drug abuse or thoughts of suicide.

You may have suicidal thoughts when you first start taking an antidepressant, especially if you are younger than 24 years of age. Your doctor will need to check on you at regular visits during the first few months of treatment or whenever your dose is changed.

Tell your doctor about any new or worsening symptoms such as: mood or behavior changes, restlessness, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless (mentally or physically) being more depressed or having thoughts of suicide or hurting yourself.

Tell your doctor right away if you become pregnant while taking this medicine. Viibryd Starter Pack may cause heart defects or serious lung problems in a newborn if you take medication during pregnancy. However, you may have a relapse of depression if you stop taking an antidepressant. Do not start or stop taking Viibryd Starter Pack during pregnancy without consulting your doctor.

Special Warnings and Precautions

Description Special Warnings and Precautions Viibryd Starter Pack is an automatic translation from the original language. Do not use this information for any medical prescription or manipulation under any circumstances. Be sure to read the original instructions for the medicine from the package. This description may contain numerous errors due to automatic translation! Keep this in mind and do not use this description!

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Use Viibryd Starter Pack as directed by your doctor. Check the label on the medication for exact dosing instructions.

  • Viibryd Starter Pack comes with an additional patient information sheet called the Medication Guide. Read it carefully. Read this again every time you top up your Viibryd Starter Pack.
  • Take Viibryd Starter Pack by mouth with food.
  • When starting Viibryd Starter Pack, your doctor may slowly increase the dose to avoid side effects. Discuss any questions or concerns with your doctor.
  • Viibryd Starter Pack may take 1 to 4 weeks to work. Do not stop taking Viibryd Starter Pack without consulting your doctor.
  • Do not suddenly stop taking Viibryd Starter Pack. You may have an increased risk of side effects. If you need to stop Viibryd Starter Pack, your doctor will gradually decrease your dose.
  • If you miss your Viibryd Starter Pack, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and return to your regular dosing schedule. Do not take 2 doses at the same time.

Ask your doctor any questions you have about how to use Viibryd Starter Pack.

There are both specific and general uses of a drug or drug. A medicine can be used to prevent a disease, treat a disease for a period, or treat a disease. It can also be used to treat a specific symptom of a disease. The use of the drug depends on the form that the patient takes. It may be more useful in the form of an injection or sometimes in the form of a tablet. The drug may be used for a single alarm symptom or life-threatening condition. While some medications can be stopped after a few days, some medications must be continued for a long period of time to benefit from them.

Viibryd Starter Pack is used to treat major depressive disorder (MDD) in adults. This medication may improve your mood, sleep, appetite, and energy levels and may help restore your interest in daily life.

Interaction with other drugs

Description Interaction with other drugs Viibryd Starter Pack is an automatic translation from the original language. Do not use this information for any medical prescription or manipulation under any circumstances. Be sure to read the original instructions for the medicine from the package. This description may contain numerous errors due to automatic translation! Keep this in mind and do not use this description! Monoamine oxidase inhibitors (MAOIs) Simultaneous use of MAOIs and serotonergic drugs, including Viibryd Starter Pack, increases the risk of developing serotonin syndrome. Viibryd Starter Pack is contraindicated in patients taking MAOIs, including MAOIs such as linezolid or intravenous methylene blue. Other serotonergic drugs Concomitant use of serotonergic drugs, including Viibryd Starter Pack and other serotonergic drugs, increases the risk of developing serotonin syndrome. Monitor patients for signs and symptoms of serotonin syndrome, especially during Viibryd Starter Pack initiation. If serotonin syndrome occurs, consider discontinuing Viibryd Starter Pack and/or concomitant serotonergic drugs. Antiplatelet agents and anticoagulants The release of serotonin by platelets plays an important role in hemostasis. Concomitant use of an antiplatelet agent or anticoagulant with Viibryd Starter Pack may increase the risk of bleeding. Inform patients of an increased risk of bleeding when using Viibryd Starter Pack and antiplatelet and anticoagulant drugs. For patients taking warfarin, closely monitor the International Normalized Ratio (INR) when starting or stopping Viibryd Starter Pack. Strong CYP3A4 inhibitors (e.g., itraconazole, clarithromycin, voriconazole) Co-administration of Viibryd Starter Pack and strong CYP3A4 inhibitors increased exposure to Viibryd Starter Pack compared with Viibryd Starter Pack alone. The dose of Viibryd Starter Pack should not exceed 20 mg once daily when a strong CYP3A4 inhibitor is being used. Strong CYP3A4 inducers (e.g., carbamazepine, phenytoin, rifampin) Co-administration of Viibryd Starter Pack and strong CYP3A4 inducers reduced exposure to Viibryd Starter Pack compared with Viibryd Starter Pack alone. Based on clinical response, consider increasing the dose of Viibryd Starter Pack over 1-2 weeks in patients taking strong CYP3A4 inducers for more than 14 days. Digoxin Digoxin is a narrow therapeutic index of the drug. The concomitant use of Viibryd Starter Pack increased the concentration of digoxin. Measure serum digoxin concentration prior to concomitant use of Viibryd Starter Pack. Continue monitoring and reduce the dose of digoxin as needed.

Drugs with no clinically significant interactions with Viibryd Starter Pack

Based on pharmacokinetic studies, no dose adjustment is required for drugs that are substrates of CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4 and/or P-glycoprotein (with the exception of drugs with a narrow therapeutic index, e.g., digoxin), when Viibryd Starter Pack is administered at the same time.

Drug Abuse and Dependence
Controlled Substance

Viibryd Starter Pack is not a controlled substance.

Abuse and Dependence

Viibryd Starter Pack has been systematically studied in animals and has not demonstrated abuse or dependence potential. Although Viibryd Starter Pack has not been systematically studied in humans for its potential for abuse, there has been no evidence of drug seeking behavior in clinical studies.

Side Effects

Description Side Effects Viibryd Starter Pack is an automatic translation from the original language. Do not use this information for any medical prescription or manipulation under any circumstances. Be sure to read the original instructions for the medicine from the package. This description may contain numerous errors due to automatic translation! Keep this in mind and do not use this description!

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What are the possible side effects of Viibryd Starter Pack?

The following adverse reactions are discussed in more detail elsewhere on the label:

  • Suicidal thoughts and behavior in children, adolescents and young adults.
  • Serotonin syndrome.
  • Increased risk of bleeding.
  • Activation of mania or hypomania.
  • Termination syndrome.
  • Seizures
  • Angular glaucoma.
  • Hyponatremia.
Experience from clinical trials

Because clinical trials are conducted under widely varying conditions and lengths of time, the frequency of adverse reactions observed in clinical trials of a medicinal product cannot be directly compared with the frequency of clinical trials of another medicinal product and may not reflect rates observed in practice.

The most frequently observed adverse reactions in patients treated with Viibryd Starter Pack with major depressive disorder (MDD) in placebo-controlled studies (incidence ≥ 5% and at least twice that of placebo) were diarrhea, nausea, vomiting and insomnia.

Patient exposure

The safety of Viibryd Starter Pack was evaluated in 3007 patients (aged 18-70 years) diagnosed with MDD who participated in clinical studies, representing 676 patient-years of exposure. In an open label 52-week study at 40 mg daily, 599 patients were exposed to Viibryd Starter Pack for a total of 348 patient-years.

The information on adverse reactions below was obtained from studies of Viibryd Starter Pack 20 mg and 40 mg per day in patients with MDD, including:

  • Four placebo-controlled studies lasting 8 to 10 weeks in 2233 patients, including 1266 patients who received Viibryd Starter Pack; and
  • An open-label 52-week study of 599 patients treated with Viibryd Starter Pack.

These studies included a titration period of 10 mg daily for 7 days followed by 20 mg daily for 7 days or up to 40 mg daily for 2 weeks. In these clinical trials, Viibryd Starter Pack was administered with food.

Adverse reactions reported as reasons for treatment discontinuation

In these studies, 7.3% of patients treated with Viibryd Starter Pack discontinued treatment due to an adverse reaction compared to 3.5% of patients treated with placebo. The most common adverse reaction leading to discontinuation in at least 1% of patients treated with Viibryd Starter Pack in placebo-controlled studies was nausea (1. 4%).

Common Adverse Reactions in Placebo Controlled Trials MDD

Table 2 shows the frequency of common adverse reactions occurring in ≥ 2% of patients treated with Viibryd Starter Pack and higher than in patients treated with placebo in MDD studies. No dose-related adverse reactions have been reported between 20 and 40 mg.

Table 2: Common adverse reactions occurring in ≥ 2% of patients treated with Viibryd Starter Pack and higher than in patients treated with placebo

System organ class preferred term placebo

N = 967

VIIBRYD Starter Pack 20 mg / day

N = 288

VIIBRYD STARED STARTER / DAY

N = 978 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 Disorders

diarrhea 10% 26% 29%
Nausea 0003

Table 3: common sexual adverse reactions that occur in ≥ 2% of patients receiving the VIIBryd Starter Pack and higher than in patients receiving placebo

Reactions are classified by body system according to the following definitions: common adverse reactions occur in at least 1/100 patients; infrequently adverse reactions occur in 1/100-1/1000 patients; rare reactions occur in less than 1/1000 patients:

Cardiac disorders: infrequently : ventricular extrasystoles

visual disturbances: infrequently : dry eye, blurred vision 0003

Nervous system: often : sedation, tremor; infrequently : Migraine

Mental Disorders: Infrequently : Panic attack

skin disorders and subcutaneous tissue: Infrequently : Hyperhydrosis, night sweots 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9,0002 Viibryd starter package after approval. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency or establish a causal relationship to drug exposure. Reports of adverse reactions temporarily associated with Viibryd Starter Pack that have been received since market launch and are not listed above include the following:

General disorders and conditions of the Administration Site: irritability

Disorders of the nervous system: Sleep paralysis

Psychic disorders: Hallucinations, suicide attempts, suicidal thoughts

skin disorders and subcutaneous flux: raw ram, generalized ram , urticaria, drug eruption

Gastrointestinal system: acute pancreatitis

Composition

Description Composition Viibryd Starter Pack is an automatic translation from the original language. Do not use this information for any medical prescription or manipulation under any circumstances. Be sure to read the original instructions for the medicine from the package. This description may contain numerous errors due to automatic translation! Keep this in mind and do not use this description!

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Viibryd Starter Pack is a new compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT (1A) receptors. It has been shown to be equally effective as other antidepressants with similar gastrointestinal side effects and possibly reduced sexual side effects and weight gain. Viibryd Starter Pack is an antidepressant that can be used as an alternative for patients who cannot tolerate other antidepressant therapy such as selective serotonin reuptake inhibitors or norepinephrine serotonin reuptake inhibitors. Treatment should be titrated to the target dose, which is 40 mg per day.

Viibryd Starter Pack price

We don't have exact price data for this medicine.
However, we will provide data for each active ingredient

The average cost of Vilazodone 40 mg per unit in online pharmacies is from $0.99 to $4.58, per package from $99 to $458.

The average cost of Vilazodone 20 mg per unit in online pharmacies is from $0.99 to $3.75, per pack from $99 to $375.

Sources:

  • https://www.drugs.com/viibryd.html
  • https://pubmed.ncbi.nlm.nih.gov/?term=viibryd-starter-pack

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Fighting depression: 10 modern drugs

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Articles

Fighting depression: 10 modern drugs

Depression is an urgent problem, the number of visits to doctors is growing every year. It can be solved by contacting a psychotherapist and taking antidepressants . These are drugs that regulate the production of hormones and biochemical processes in the body. It is strictly forbidden to prescribe them to oneself, as these are complex drugs with certain restrictions, side effects effects . The doctor must authorize their appointment and control the intake. We will tell you which of them are the most effective and common in medicine, how many they have pluses and minuses.

What is meant by

depression

Doctors have known it since ancient Greece and Egypt. Hippocrates described it as melancholy - a condition that is accompanied by anxiety, despondency, insomnia, refusal of food, irritability. Most often, the cause is childhood trauma or severe, frequent stress in adulthood. There are many provoking factors: the death of a loved one, deterioration of living conditions, alcoholism, brain diseases. Such cases are referred to as psychogenic depression.

The second type is endogenous. The problem appears not from large external shocks, but because of internal causes. A person is constantly dissatisfied with himself, subjecting himself to criticism. Many patients have panic attacks , haunted by a feeling of fear, anxiety.

How long the period of depression lasts

Many people mistake ordinary periods of low mood for depression. If they do not last long and are quickly replaced by periods of recovery, then we are not talking about a depressive state. The problem is obvious when the symptoms persist for months and dramatically change a person's life. Then you need to see a doctor.

What happens to the body

The most common theory is that there is a malfunction of neurotransmitters located in the brain. These substances transmit signals from neuron to neuron and are responsible for a person's mood. Dysfunction leads to a slowdown in the rate of this transmission and a decrease in the number of neurotransmitters themselves. Serotonin, which is called the "hormone of happiness", suffers the most. For clarity, this biochemical process can be compared, for example, with a drop in blood sugar levels in diabetes mellitus.

How is depression treated

Depression has been treated in different ways. In the ancient world - emetics and laxatives. In the Renaissance - wine and sunbathing. In the Age of Enlightenment - external stimuli, for example, insects. The 19th century brought new recipes - in particular, a solution of camphor in tartaric acid. The treatment also included the use of drugs, which are now no longer allowed for sale , and some are recognized as narcotic.

Obviously, all these drugs had no effect on increasing the amount of serotonin. And the treatment is precisely to normalize its production. This was done after creating modern antidepressants , which have a minimum of side effects, are safe for the body and are not addictive. These are drugs, the action of which is aimed precisely at balancing the disturbed balance of neurotransmitters: serotonin, norepinephrine, dopamine.

Prescription

If a healthy person takes antidepressants , there will be no effect . For a depressed patient, taking them will help:

  • improve psychological state;
  • get rid of irritability;
  • panic fear;
  • increase mental and physical activity;
  • to overcome the dreary mood.

Psychiatrists prescribe antidepressants for chronic back pain, headaches. And also with irritable bowel syndrome, incontinence and other cases when the body stops producing its own painkillers. Medication helps restore pain suppression mechanisms.

You can only take these drugs with a doctor's prescription, as many of them are strong stimulants . Self-administration may cost dearly - the condition may worsen. Only a doctor will correctly calculate how many medicines to take per day. In parallel with the treatment by a psychiatrist, a neurologist, a consultation of a psychotherapist is required.

Precautions

  • Prescribed drug start drinking from a small dose - the first couple of days they take a quarter of a tablet. Gradually increase the dose to normal. So the body adapts better. Finish the course by reducing the dose.
  • The first effect of appears only 2 weeks after the start of administration. Steady action - six months later. All this time, you need to take the remedy without making passes, breaks.
  • Products are not combined with melatonin, St. John's wort, products and dietary supplements based on sibutramine, 5-HTP. Their combination can raise serotonin to dangerous levels. Also, you can not combine them with monoamine oxidase inhibitors, for example, Cipralex. When writing a prescription, the doctor takes these points into account.

  • Drinking antidepressants is better in parallel with visits to a psychotherapist. If the drugs normalize the biochemical processes in the body, then this doctor will help normalize the psychological state after depression.

The best antidepressants

In medicine, they have long argued that some drugs give only a placebo effect. The purpose of the study was to find out which of them are the most effective and valid . The project involved 116 thousand patients, and its results were published by the authoritative edition of the Lancet. We offer a list of the best.

1. Agomelatine

New generation drug. Agomelatine is used for severe depressive disorders, high levels of anxiety. Enhances the release of dopamine and norepinephrine, stimulates melatonin receptors. The standard therapeutic dose is 25-50 mg 1 time / day. Helps to restore the normal structure of sleep, get rid of anxiety and panic attacks attacks

Pros

+ Does not adversely affect attention and memory.

+ No lethargy during the day.

+ No sexual deviations.

+ No correlation with blood pressure.

+ Do not reduce dosage upon discontinuation.

Cons

— In 1-10% of cases, increased sweating, diarrhea, constipation.

- Possible increased fatigue, drowsiness.

- There are no evidence-based safety studies in people with renal or hepatic insufficiency, therefore, such patients are advised to refrain from taking drugs with active ingredient agomelatine.

2. Amitriptyline

Tricyclic antidepressant. Moreover, the World Health Organization considers Amitriptyline the most reliable in this group. The standard dose is 200-250 mg / day. The action is to block the reuptake of neurotransmitters. A good remedy for moderate to severe disorders of the endogenous type. Additionally, it has a sedative and hypnotic effect. Effective in the treatment of neuropathic pain, for the prevention of migraine.

Pluses

+ Drugs with active ingredient amitriptyline are inexpensive.

+ High reliability, minimum side effects.

+ Relatively safe during breastfeeding.

Cons

— Possible side effect in the form of blurred vision, dry mouth.

- Lowering blood pressure.

- Some patients experience constipation.

- Drowsiness.

3. Escitalopram

It belongs to the group of modern serotonin reuptake inhibitors (SSRIs). Most often, it is recommended to take for anxiety, panic attacks. It is taken once, the standard dose is 10 mg per day. Escitalopram has a milder effect and is prescribed to patients who are contraindicated in tricyclic drugs.

Pluses

+ A lasting effect occurs after 3 months.

+ Indicated for patients with disorders of the cardiovascular system.

+ Soft action.

Cons

- In some patients, the functions of the gastrointestinal tract are disturbed, which is most often expressed in diarrhea.

— Anxiety may increase in the first 2 weeks, therefore it is recommended to start treatment with low doses and gradually increase them.

- Contraindicated in pregnancy and lactation.

4. Mirtazapine

A drug of the tetracyclic group. Mirtazapine - good stimulant for anxious depressions, has a moderate sedative effect. The average amount is 30 mg / day, it must be consumed once. Usually it is prescribed to patients who lose interest in life, cease to experience joy, pleasure. Effective in the correction of sleep, in particular, early awakenings.

Pros

+ Earlier onset of action than SSRIs (1 week).

+ Combines well with most drugs in the general group.

+ Full effect in 4 weeks.

+ Does not affect sexual function.

Cons

- The active substance mirtazapine is contraindicated in diabetes mellitus, arterial hypotension, increased intraocular pressure.

— During the admission period, you must drive carefully and engage in potentially dangerous types of work.

- 18% of patients experience drowsiness, 15% dry mouth, 5% weight loss. Other side effects occur in 1-3% of cases.

5. Paroxetine

Belongs to the SSRI group, is used most often for severe anxiety, panic, social phobia, nightmares, stress after trauma. Paroxetine can resolve the problems of anxious depression, anxiety-phobic disorders. Take once a day at a dose of 20 mg.

Pros

+ The most powerful stimulant among SSRIs.

+ Anxiety and insomnia pass quickly.

+ Minimal side effects in the form of vomiting, diarrhea.

+ Suitable for patients with cardiovascular problems.

Cons

— Not suitable for patients with severe motor, mental inhibition.

- Reduces libido.

- Harmful to the fetus when taken during pregnancy.

6. Fluoxetine

One of the most widely used antidepressants in the SSRI group. Known as Prozac. Fluoxetine is also known as a good mood stimulant. Patients have a feeling of fear, tension, anxiety, gloomy dislike for others. Depending on the indications, the average daily dose is 20-60 mg.

Pluses

+ There is practically no effect on the work of the heart.

+ Does not cause sedation.

+ Effective for patients with motor retardation and excessive daytime sleepiness.

Cons

- May cause weight loss.

— Hypoglycemia is possible in diabetes mellitus.

- Contraindicated in severe renal impairment.

7. Fluvoxamine

Another SSRI drug. Fluvoxamine is similar to Prozac Fluoxetine but is fast acting and may cost cheaper. The effect is in a more active slowing down of the reuptake of serotonin by neurons. It is indicated for depression of various origins, as well as obsessive-compulsive disorders. The average daily dose is 100 mg.

Pros

+ Lower price than traditional Prozac.

+ Faster action than him.

+ Relatively minor side effects (diarrhea, dry mouth, drowsiness).

Cons

- Contraindicated in diabetes.

- Pregnant women - with caution, lactation - prohibited.

- Causes nausea in some patients.

8. Sertraline

One of the widely used and universal drugs of the SSRI group. They treat almost any depressive condition, panic disorder, social phobia. However, in severe clinical cases, sertraline may not be effective enough. The standard dose is 50 mg/day.

Pros

+ No cardiotoxicity.

+ The patient's psychomotor activity does not change.

+ Does not increase body weight.

+ Combines well with other groups of antidepressants.

Cons

— In the first 2 weeks there may be problems with sleep, diarrhea.

- Side effects of a sexual nature.

- Contraindicated in pregnant women.

9. Escitalopram

The drug is classified as an SSRI. Its difference is in its effectiveness in depression, which is accompanied by involuntary movements (tic, tremor, chewing, smacking). Escitalopram is prescribed to patients with panic, anxiety, phobias, obsessive thoughts or actions. The daily dose is 20 mg.

Pluses

+ Effective in tardive dyskinesia.

+ One of the most powerful SSRIs.

+ More pronounced thymoleptic effect (improvement of mood) compared to many antidepressants of the same group.

Cons

- In some patients, anxiety increases within 2 weeks after starting treatment.

- Gastrointestinal disorders, insomnia, agitation are possible.

Men Women
Placebo

N = 416

Viibryd Starter Pack 20 mg/day

N = 122

Viibryd Starter Pack 40 mg/day

N = 417


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