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Effexor xr 37.5mg


Effexor XR Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Warnings:

Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits. However, a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. It is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition.

Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.

Warnings:

Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits. However, a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. It is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition.

Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.

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Uses

Venlafaxine is used to treat depression, anxiety, panic attacks, and social anxiety disorder (social phobia). It may improve your mood and energy level and may help restore your interest in daily living. It may also decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. Venlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.

How to use Effexor XR

Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start using venlafaxine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually once daily with food, either in the morning or evening.

Do not crush, chew, or dissolve this medication. Doing so can release all of the drug at once, increasing the risk of side effects. Swallow whole without crushing or chewing.

If you are taking the capsules, swallow them whole. If you have trouble swallowing the capsules whole, you may open the capsule and sprinkle the contents onto a spoonful of applesauce. Swallow all of the mixture right away without chewing. Drink a glass of water after each dose.

The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Keep taking this medication even if you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Also, you may experience symptoms such as confusion, mood swings, blurred vision, headache, tiredness, sleep changes, and brief feelings similar to electric shock. Your dose may need to be gradually decreased to reduce side effects. Report any new or worsening symptoms right away.

It may take several weeks to feel the benefit of this medication. Tell your doctor if your condition lasts or gets worse.

Side Effects

See also Warning section.

Nausea, drowsiness, dizziness, dry mouth, constipation, loss of appetite, blurred vision, nervousness, trouble sleeping, unusual sweating, or yawning may occur. If any of these effects last or get worse, tell your doctor promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high.

Tell your doctor right away if you have any serious side effects, including: easy bruising/bleeding, decreased interest in sex, changes in sexual ability, muscle cramps/weakness, shaking (tremor).

Get medical help right away if you have any very serious side effects, including: cough that doesn't go away, shortness of breath, chest pain, severe/pounding headache, black/bloody stools, vomit that looks like coffee grounds, eye pain/swelling/redness, widened pupils, vision changes (such as seeing rainbows around lights at night), seizure.

This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking venlafaxine, tell your doctor or pharmacist if you are allergic to it; or to desvenlafaxine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, personal or family history of glaucoma (angle-closure type), high blood pressure, heart problems (such as heart failure, previous heart attack), high cholesterol, kidney disease, liver disease, seizure disorder, thyroid disease.

This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially dizziness when standing. Older adults may also be more likely to develop a type of salt imbalance (hyponatremia), especially if they are taking "water pills" (diuretics). Dizziness and salt imbalance can increase the risk of falling. Older adults may also be at greater risk for bleeding while using this drug.

Children may be more sensitive to the side effects of the drug, especially loss of appetite and weight loss. Monitor weight and height in children who are taking this drug.

During pregnancy, this medication should be used only when clearly needed. It may harm an unborn baby. Also, babies born to mothers who have used this drug during the last 3 months of pregnancy may rarely develop withdrawal symptoms such as feeding/breathing difficulties, seizures, muscle stiffness, or constant crying. If you notice any of these symptoms in your newborn, tell the doctor promptly.

Since untreated mental/mood problems (such as depression, anxiety, panic attacks) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss the benefits and risks of using this medication during pregnancy with your doctor.

This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen/naproxen, "blood thinners" such as dabigatran/warfarin).

Aspirin can increase the risk of bleeding when used with this medication. However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually 81-162 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and at least 7 days after treatment with this medication. Ask your doctor when to start or stop taking this medication.

The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/"ecstasy," St. John's wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, other SNRIs such as duloxetine/milnacipran), tryptophan, among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Venlafaxine is very similar to desvenlafaxine. Do not take medications containing desvenlafaxine while using venlafaxine.

This medication may interfere with certain lab tests (including urine tests for amphetamines), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.

Does Effexor XR interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe drowsiness, seizures, fast/irregular heartbeat.

Do not share this medication with others.

Keep all regular medical and psychiatric appointments. Laboratory and/or medical tests (such as blood pressure, cholesterol) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Venlafaxine (Effexor) | NAMI: National Alliance on Mental Illness

Brand names:

  • Effexor®
    • Tablets (immediate release): 25 mg, 37. 5 mg, 50 mg, 75 mg, 100 mg
  • Effexor XR®
    • Capsules (extended release): 37.5 mg, 75 mg, 150 mg
  • Venlafaxine
    • Tablets (extended release): 37.5, 75 mg, 150 mg, 225 mg
    • Tablets (immediate release): 25 mg, 37.5 mg, 50 mg 75, mg 100 mg


Generic name: venlafaxine (ven la FAX een)

All FDA black box warnings are at the end of this fact sheet. Please review before taking this medication.

What Is Venlafaxine And What Does It Treat?

Venlafaxine is an antidepressant medication that works in the brain. It is approved for the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), panic disorder, and social anxiety disorder (social phobia).

Symptoms of depression include:

  • Depressed mood - feeling sad, empty, or tearful
  • Feeling worthless, guilty, hopeless, and helpless
  • Loss of interest or pleasure in your usual activities
  • Sleep and eat more or less than usual (for most people it is less)
  • Low energy, trouble concentrating, or thoughts of death (suicidal thinking)
  • Psychomotor agitation (‘nervous energy’)
  • Psychomotor retardation (feeling like you are moving and thinking in slow motion)
  • Suicidal thoughts or behaviors


Generalized Anxiety Disorder (GAD) occurs when a person experiences excessive anxiety or worry for at least six months. Other symptoms include:

  • Restlessness
  • Fatigue (low energy, feeling tired all the time)
  • Difficulty concentrating
  • Irritability
  • Muscle tension
  • Sleep disturbance (difficulty falling asleep or waking up in the middle of the night)


Panic Disorder occurs when a person experiences unexpected and repeated episodes of intense fear. These episodes have physical symptoms including chest pain, shortness of breath, heart palpitations, sweating, dizziness, and nausea. Fear of future episodes is also part of panic disorder.

Social phobia/social anxiety disorder is a fear of situations where one may feel as if they are being judged by others. Symptoms include:

  • Blushing
  • Difficulty talking
  • Nausea
  • Sweating
  • Shaking


Venlafaxine may also be helpful when prescribed “off-label” for attention-deficit/hyperactivity disorder (ADHD) in adults and children/adolescents, diabetic neuropathy, migraine prevention, hot flashes, obsessive compulsive disorder (OCD), posttraumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD) . “Off-label” means that it hasn't been approved by the Food and Drug Administration for this condition. Your mental health provider should justify his or her thinking in recommending any “off-label” treatment. They should be clear about the limits of the research around that medication and if there are any other options.

What Is The Most Important Information I Should Know About Venlafaxine?

Do not stop taking venlafaxine, even when you feel better. With input from you, your health care provider will assess how long you will need to take the medicine.

Missing doses of venlafaxine may increase your risk for relapse in your symptoms.

Stopping venlafaxine abruptly may result in one or more of the following withdrawal symptoms: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin).

Depression is also a part of bipolar illness. People with bipolar disorder who take antidepressants may be at risk for "switching" from depression into mania. Symptoms of mania include "high" or irritable mood, very high self-esteem, decreased need for sleep, pressure to keep talking, racing thoughts, being easily distracted, frequently involved in activities with a large risk for bad consequences (for example, excessive buying sprees).

Medical attention should be sought if serotonin syndrome is suspected. Please refer to serious side effects for signs/symptoms.

Are There Specific Concerns About Venlafaxine And Pregnancy?

If you are planning on becoming pregnant, notify your health care provider to best manage your medications. People living with MDD who wish to become pregnant face important decisions. Untreated MDD has risks to the fetus, as well as the mother. It is important to discuss the risks and benefits of treatment with your doctor and caregivers. For women who take antidepressant medications during weeks 13 through the end of their pregnancy (second and third trimesters), there is a risk that the baby can be born before it is fully developed (before 37 weeks).

Caution is advised with breastfeeding since venlafaxine does pass into breast milk.

What Should I Discuss With My Health Care Provider Before Taking Venlafaxine?

  • Symptoms of your condition that bother you the most
  • If you have thoughts of suicide or harming yourself
  • Medications you have taken in the past for your condition, whether they were effective or caused any adverse effects
  • If you experience side effects from your medications, discuss them with your provider. Some side effects may pass with time, but others may require changes in the medication.
  • Any other psychiatric or medical problems you have, including a history of bipolar disorder
  • All other medications you are currently taking (including over the counter products, herbal and nutritional supplements) and any medication allergies you have
  • Other non-medication treatment you are receiving, such as talk therapy or substance abuse treatment. Your provider can explain how these different treatments work with the medication.
  • If you are pregnant, plan to become pregnant, or are breastfeeding
  • If you drink alcohol or use drugs


How Should I Take Venlafaxine?

Venlafaxine immediate release tablets are usually taken two or three times per day with or without food. The extended release tablets and capsules are taken one time per day with or without food.

Typically patients begin at a low dose of medicine and the dose is increased slowly over several weeks.

The dose usually ranges from 37.5 mg to 300 mg. Only your health care provider can determine the correct dose for you.

Extended release tablets: swallow whole; do not chew, crush, or break

Extended release capsules: swallow whole or sprinkle onto food, such as applesauce or pudding and eat immediately.

Consider using a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member or friend to remind you or check in with you to be sure you are taking your medication.

What Happens If I Miss A Dose Of Venlafaxine?

If you miss a dose of venlafaxine, take it as soon as you remember, unless it is closer to the time of your next dose. Discuss this with your health care provider. Do not double your next dose or take more than what is prescribed.

What Should I Avoid While Taking Venlafaxine?

Avoid drinking alcohol or using illegal drugs while you are taking antidepressant medications. They may decrease the benefits (e.g., worsen your condition) and increase adverse effects (e.g., sedation) of the medication.

What Happens If I Overdose With Venlafaxine?

If an overdose occurs, call your doctor or 911. You may need urgent medical care. You may also contact the poison control center at 1-800-222-1222.

A specific treatment to reverse the effects of venlafaxine does not exist.

What Are The Possible Side Effects Of Venlafaxine?

Common side effects

  • Headache, nausea, diarrhea, dry mouth, increased sweating
  • Feeling nervous, restless, fatigued, sleepy or having trouble sleeping (insomnia)

These will often improve over the first week or two as you continue to take the medication.

  • Sexual side effects, such as problems with orgasm or ejaculatory delay
  • Increased blood pressure

These often do not improve over time.

Rare/serious side effects

Increased heart rate, low blood pressure, increased salivation, irregular menstrual cycle, increased frequency of urination, changes in taste, low sodium (symptoms of low sodium levels may include headache, weakness, difficulty concentrating and remembering), teeth grinding, difficulty urinating, angle closure glaucoma (symptoms of angle closure glaucoma may include eye pain, changes in vision, swelling or redness in or around eye).

Serotonin syndrome (symptoms may include shivering, diarrhea, confusion, severe muscle tightness, fever, seizures, and death)

SNRI antidepressants including venlafaxine may increase the risk of bleeding events. Combined use of aspirin, nonsteroidal anti-inflammatory drugs (e.g., ibuprofen, naproxen), warfarin, and other anti-coagulants may increase this risk. This may include gums that bleed more easily, nose bleed, or gastrointestinal bleeding. Some cases have been life threatening.

Are There Any Risks For Taking Venlafaxine For Long Periods Of Time?

To date, there are no known problems associated with long term use of venlafaxine. It is a safe and effective medication when used as directed.

What Other Medications May Interact With Venlafaxine?

Venlafaxine should not be taken with or within 2 weeks of taking monoamine oxidase inhibitors (MAOIs). These include phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®), rasagiline (Azilect®), and selegiline (Emsam®).

Although rare, there is an increased risk of serotonin syndrome when venlafaxine is used with other medications that increase serotonin, such as other antidepressants, migraine medications called “triptans” (e.g., Imitrex®), some pain medications (e.g., tramadol (Ultram®), and the antibiotic linezolid (Zyvox®).

Venlafaxine may increase the effects of other medications that can cause bleeding (e. g., ibuprofen (Advil®, Motrin®), warfarin (Coumadin®) and aspirin).

How Long Does It Take For Venlafaxine To Work?

Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.

Summary of FDA Black Box Warnings

Suicidal thoughts or actions in children and adults

Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients with major depressive disorder (MDD), both adult and pediatric, may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in behavior, whether or not they are taking antidepressant medications. This risk may persist until significant remission occurs.

In short-term studies, antidepressants increased the risk of suicidality in children, adolescents, and young adults when compared to placebo. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24. Adults age 65 and older taking antidepressants have a decreased risk of suicidality. Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or health care professional. All patients being treated with antidepressants for any indication should watch for and notify their health care provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.

 

Provided by

(December 2020)

©2020 The College of Psychiatric and Neurologic Pharmacists (CPNP) and the National Alliance on Mental Illness (NAMI). CPNP and NAMI make this document available under the Creative Commons Attribution-No Derivatives 4. 0 International License. Last Updated: January 2016.

This information is being provided as a community outreach effort of the College of Psychiatric and Neurologic Pharmacists. This information is for educational and informational purposes only and is not medical advice. This information contains a summary of important points and is not an exhaustive review of information about the medication. Always seek the advice of a physician or other qualified medical professional with any questions you may have regarding medications or medical conditions. Never delay seeking professional medical advice or disregard medical professional advice as a result of any information provided herein. The College of Psychiatric and Neurologic Pharmacists disclaims any and all liability alleged as a result of the information provided herein.

Effexor - Pharmacy in Israel

  • Description
  • Delivery within Israel
  • Delivery to Russia
  • Delivery to Belarus

Description

Antidepressant from the group of selective serotonin and norepinephrine reuptake inhibitors. Depression is a very serious reason to see a doctor, you should not ignore the problem that has arisen. You will be prescribed an antidepressant that will help you and restore the lost quality of life and the ability to enjoy. Thinking where to buy Effexor? We recommend you our reliable partner, a pharmacy in the center of Tel Aviv. Buying a drug is simple, contact us through the website, we will help you with placing an order and purchasing.

Mechanism of action

The mechanism of the antidepressant action of effexor is to increase the activity of neurotransmitters during the transmission of nerve impulses to the central nervous system.
Venlafaxine and its main metabolite, O-desmethyl venlafaxine, are potent inhibitors of neuronal reuptake of serotonin and norepinephrine and inhibit dopamine reuptake. Single and long-term administration of venlafaxine and EFA reduces β-adrenergic reactions. nine0013

Application protocol

The drug is taken orally, during meals, swallowed whole, washed down with water.
The recommended starting dose is 75 mg/day. If clinically indicated, the dose may be increased to 375 mg/day, but due to the risk of dose-dependent side risks, this should be done only after clinical evaluation by a specialist. Treatment should continue for at least several months.

Efficacy

Effexor has been shown to be effective in the treatment of depressive disorders in clinical studies. There is a pronounced antidepressant effect, with a decrease in signs of emotional lability, irritability, which leads to an improvement in the quality of life and daily activity. nine0013

Indications

  • Treatment and prevention of recurrence of major depressive episodes
  • Treatment of generalized anxiety disorder.
  • Treatment of social anxiety disorder.
  • Treatment of panic disorder with or without agoraphobia.

Contraindications

  • hypersensitivity to effexor or any of the components of the preparation
  • concomitant use with MAO inhibitors
  • severe renal and/or liver dysfunction
  • patients under the age of 18
  • pregnancy or lactation

Side effects

  • agranulocytosis, aplastic anemia, pancytopenia, neutropenia, thrombocytopenia, increased blood prolactin concentration
  • anaphylactic reaction
  • dizziness, asthenia, weakness, insomnia
  • tachycardia, atrial fibrillation, QT prolongation
  • irritability, tremor, muscle hypertonicity, paresthesia
  • increased blood pressure, sedation, fatigue, asthenia, chills
  • hyperemia of the skin
  • decreased appetite, nausea, vomiting, taste perversion
  • decreased libido, erectile dysfunction and/or ejaculation, urinary incontinence, urinary incontinence, anorgasmia, menorrhagia,
  • visual impairment, mydriasis, balance disorder, tinnitus, vertigo
  • depersonalization, nightmares, nervousness, suicidal mood, agitation, confusion, mania, delirium. nine0004

Interaction

Effexor is an inhibitor of the cytochrome P450 2D6 isoenzyme and leads to an increase in the concentration of tricyclic antidepressants, carbamazepine, and some atypical antipsychotics. The drug is not used in combination with MAO inhibitors. Simultaneous use with clozapine increases the concentration of effexor, which can lead to the development of side effects. Drinking alcohol should be avoided while taking Effexor.

Storage conditions

Store in a place protected from light at a temperature not exceeding 25°C, out of the reach of children.

Delivery in Israel

Delivery in Israel

Our pharmacy delivers drugs quickly in Tel Aviv and throughout Israel.

The drug is transported in a refrigerator, while maintaining the temperature regime. This allows you not to spoil the medicine.

How can I order delivery of medication?

To place an order for the delivery of medicines in Tel Aviv or Israel, please contact our pharmacist by phone in the "Contacts" section. We will inform you as soon as possible and the shipping cost. nine0013

Delivery to Russia

Delivery to Russia

Delivery is carried out by the Israeli company Bio Logistica LTD, which specializes in the legal transportation of medicines and biological materials.

Registration of customs documents for the delivery of medicines, as well as airport security permits, accompanying documentation.

The logistics company we cooperate with helps with all these questions. nine0013

To find out the cost of delivering medicines to your country and city, contact Bio Logistica LTD directly via WhatsApp and they will advise you free of charge.

WhatsApp +7 999 542 02 88 (Russian speaking manager)

Every Israeli pharmacy offers discounts on certain medicines. Before ordering medicines from Israel, we recommend that you contact our pharmacists to clarify the availability of discounts and special offers.

In this case, you get the opportunity to return VAT included in the price in the amount of 15% at the TAX FREE counter at the airport. Ben Gurion. nine0013

All documents required for the TAXFREE refund are processed at the pharmacy after the purchase.

Please note that VAT refunds do not apply to special offers.

Delivery to Belarus

Delivery to Belarus

Delivery is carried out by the Israeli company Bio Logistica LTD, which specializes in the legal transportation of medicines and biological materials.

Registration of customs documents for the delivery of medicines, as well as airport security permits, accompanying documentation. nine0013

The logistics company we cooperate with helps with all these questions.

To find out the conditions and cost of delivery to Belarus, contact the representative of Bio Logistica LTD in Belarus by phone and they will advise you free of charge.

WhatsApp +7 999 542 02 88 (Russian speaking manager)

Every Israeli pharmacy offers discounts on certain medicines. Before ordering medicines from Israel, we recommend that you contact our pharmacists to clarify the availability of discounts and special offers. nine0013

In this case, you get the opportunity to return VAT included in the price in the amount of 15% at the TAX FREE counter at the airport. Ben Gurion.

All documents required for the TAXFREE refund are processed at the pharmacy after the purchase.

Please note that VAT refunds do not apply to special offers.

Venlafaxine (Vipax) - Pharmacy in Israel

A new generation antidepressant from the group of selective serotonin and norepinephrine reuptake inhibitors. nine0013

Treating depression should be taken seriously, so the drug is prescribed only by prescription. By contacting our pharmacy, you can buy Venlafaxine and be 100% sure of its authenticity and quality. We will provide you with the original receipt and quality certificates for the drug.

Mechanism of action

The mechanism of the antidepressant action of the drug is associated with its ability to enhance the activity of neurotransmitters during the transmission of nerve impulses to the central nervous system. Venlafaxine and its main metabolite O-desmethylvenlafaxine equally effectively affect the reuptake of neurotransmitters, while they do not have affinity for muscarinic, adrenergic, histaminergic, 5-HT1- and 5-HT2-serotonin receptors, and do not suppress MAO activity. nine0013

Application protocol

The drug is taken orally, during meals, without chewing and drinking liquid, preferably at the same time.

The recommended starting dose is 75 mg twice daily (37.5 mg once, twice daily). The dose can be gradually increased to 150 mg/day, depending on the efficacy of venlafaxine and its tolerability.

Effectiveness

Venlafaxine has been shown to be effective in the treatment of depression in numerous studies. The clinical effect of venlafaxine is characterized by a distinct antidepressant effect, while the severity of affective and anxious disorders decreases. The antidepressant effect is expressed in a subjective improvement in mood, a decrease in the severity of affective disorders, signs of emotional lability and manifestations of irritable weakness syndrome, improved sleep, and increased activity in everyday life.

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