Ambien versus xanax
Differences, similarities, and which is better for you
Drug overview & main differences | Conditions treated | Efficacy | Insurance coverage and cost comparison | Side effects | Drug interactions | Warnings | FAQ
If you or a loved one experience insomnia or anxiety, you are not alone. The National Institutes of Health estimates that about 30% of the U.S. population struggles with sleep problems; other estimates are much higher. Anxiety disorders affect 40 million American adults every year. Two popular prescription drugs for these conditions are Ambien (for insomnia) and Xanax (for anxiety/panic attacks).
Ambien (zolpidem) is a sedative-hypnotic drug (sleep aid), which works on receptors in the brain, helping you to fall asleep. Some people refer to these types of medications as “sleeping pills.” Ambien slows brain activity, allowing you to fall asleep more quickly. Ambien CR is an extended-release tablet with two layers—one to help you fall asleep, and another to help you stay asleep.
Xanax (alprazolam) is in the benzodiazepine class of drugs, and works in the central nervous system (CNS). Benzodiazepines work by increasing activity at receptors for gamma-aminobutyric acid (GABA), a neurotransmitter. By doing this, benzodiazepines produce a relaxing and calming effect. A dose of Xanax starts working within about one hour, and the effects last for about five hours (the extended-release tablet lasts up to about 11 hours).
Because of the potential for abuse and/or psychological or physical dependence, both Ambien and Xanax are controlled substances and are classified as Schedule IV drugs.
What are the main differences between Ambien and Xanax?
Ambien (What is Ambien?) is categorized as a sedative-hypnotic. The generic name of Ambien is zolpidem, or zolpidem tartrate. It is available in tablet form as an immediate-release or extended-release tablet. Ambien should be taken immediately before bedtime, just before getting into bed, when you have at least seven to eight hours to sleep.
Food can decrease the absorption of Ambien, so it’s best taken on an empty stomach. The recommended starting dose for women is 5 mg at bedtime, and the recommended starting dose for men is 5 or 10 mg at bedtime. Patients who are elderly or have mild to moderate liver problems should start with the 5 mg dose as well. (Patients with severe liver problems should not take Ambien.)
Xanax (What is Xanax?) is a benzodiazepine available in both brand and generic form. The generic name of Xanax is alprazolam. It is available in tablet form (immediate-release or extended-release) and as an oral concentrate.
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Conditions treated by Ambien vs. Xanax
Ambien is indicated for the treatment of insomnia, with difficulty initiating sleep. It should be used for short-term treatment. (Ambien CR is used in patients who have trouble falling asleep and staying asleep.
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Xanax is indicated for the short-term relief of the symptoms of anxiety, and short-term relief of anxiety associated with depressive symptoms. Xanax is also indicated for the treatment of panic disorder, with or without agoraphobia. (Xanax XR is indicated for panic disorder with or without agoraphobia, as well.)
Is Ambien or Xanax more effective?
There are no studies comparing Ambien to Xanax because they are different drugs used for different indications. If you have sleep problems, where you have trouble falling and/or staying asleep, Ambien may be an appropriate medication for you. If you are experiencing anxiety or panic disorder, Xanax may be the right drug for you. The best drug for you can only be determined by your healthcare provider, who can take into account your symptoms, medical condition(s) and history, and any medications you take that could potentially interact with Ambien or Xanax.
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Coverage and cost comparison of Ambien vs.
XanaxAmbien is usually covered by private insurance and Medicare Part D in its generic form of zolpidem. The brand-name product may not be covered or may have a much higher copay. A common prescription is for 30 tablets of 10 mg zolpidem and would cost about $60-$100 out of pocket. A SingleCare card can lower the price of generic Ambien to about $10.
Xanax is typically covered by private insurance and Medicare Part D in the generic form of alprazolam. The brand-name Xanax may not be covered or may have a high copay. A typical prescription of alprazolam would be for 60 tablets of 0.5 mg and cost about $33 out-of-pocket. Using a SingleCare card for generic Xanax can bring the price down to as little as $10.
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Common side effects of Ambien vs. Xanax
The most common side effects of Ambien are drowsiness, dizziness, headache, and diarrhea. Other side effects may occur, such as palpitations, a drugged feeling, lightheadedness, abnormal dreams, and sinusitis.
Side effects of Xanax usually increase with higher doses. The most common side effects of Xanax are sedation, dizziness, and weakness. Other side effects may include fatigue, lightheadedness, memory problems/memory loss, confusion, depression, euphoria, suicidal thoughts/attempt, incoordination, lack of energy, dry mouth, convulsions/seizures, vertigo, visual problems, slurred speech, sexual problems, headache, coma, respiratory depression, weight gain or weight loss, worsening of sleep apnea or obstructive pulmonary disease, and gastrointestinal symptoms including nausea, constipation, or diarrhea.
Other, serious side effects may occur. Consult your healthcare professional for a complete list of side effects.
Source: DailyMed (Ambien), DailyMed (Xanax)
Drug interactions of Ambien vs. Xanax
Because of its CNS depressant effects, Ambien should not be taken with other drugs that have the same effect, such as opioids, benzodiazepines, antidepressants, and alcohol, due to additive effects.
Ambien should not be taken with rifampin, because rifampin can decrease Ambien levels. Ambien should not be taken with ketoconazole (or the Ambien dose should be lowered), because ketoconazole can increase Ambien levels.
Xanax should not be taken in combination with opioid painkillers, due to increased risk of sedation, respiratory depression, and overdose, possibly leading to death. If no other combination is possible, the patient should receive each medication at the lowest possible dose and for the shortest duration, and be closely monitored. Benzodiazepines also should not be taken with other CNS depressants such as alcohol, antipsychotics, antidepressants, sedating antihistamines, and anticonvulsants.
Alcohol should not be used with Ambien or Xanax.
Other drug interactions may occur. Consult your healthcare provider for a full list of drug interactions.
Warnings of Ambien and Xanax
Ambien:
- Ambien has a boxed warning, which is the strongest warning required by the FDA.
Complex sleep behaviors have been reported with Ambien use. These may include sleep-walking, sleep-driving, and engaging in other activities (such as cooking, making phone calls, having sex) while not fully awake. Some of these actions could result in serious injury or death. Ambien should be discontinued immediately if this behavior occurs. - Due to CNS depressant effects, Ambien has additive effects with other CNS depressants (see drug interaction section). The combination should be avoided, or the dosage of either or both medication(s) may be adjusted if the combination cannot be avoided. Your healthcare provider can determine the best course of action in this scenario. Ambien should especially not be used with other CNS depressants at bedtime or in the middle of the night.
- Ambien should be taken immediately before bed, just before getting into bed, when you have time to sleep for at least seven to eight hours, due to the risk of next-day psychomotor impairment (including impaired driving).
The risk of impairment is increased if Ambien is taken with less than 7-8 hours of sleep remaining; if a higher than recommended dose is taken; or if Ambien is taken with other CNS depressants, alcohol, or other drugs that increase Ambien levels. - A full night of sleep (seven to eight hours) is recommended due to the risk of drowsiness, prolonged reaction time, dizziness, sleepiness, blurred or double vision, reduced alertness, and impaired driving the morning after taking Ambien. Ambien can also put patients, especially elderly patients, at higher risk of falls.
- Sleep problems can be a sign of another disorder, so the patient should be evaluated.
- Rare but serious cases of anaphylaxis have been reported, requiring emergency medical attention. Swelling of the tongue, throat, glottis, or larynx (angioedema) can be dangerous or fatal. If angioedema occurs, seek emergency medical attention, stop Ambien, and do not take it again.
- Abnormal thinking and changes in behavior have been reported in patients taking Ambien, including hallucinations.
Any changes in behavior should be immediately evaluated. - Patients who are depressed and take Ambien should be monitored for worsening of depression and suicidal thoughts and actions. Patients and caregivers should be aware of this possibility, and immediate medical treatment should be sought in the case of suicidal thoughts or action. Because of the risk of intentional overdose, the lowest number of tablets should be prescribed.
- Because of the potential for respiratory depression, Ambien should be used with caution in patients with breathing problems such as sleep apnea.
- Ambien should not be used in patients with severe liver problems.
- Patients who take Ambien should be monitored for tolerance, abuse, and dependence. Withdrawal symptoms may occur following abrupt discontinuation of Ambien.
- Ambien CR tablets are designed to release over time and should be swallowed whole. Ambien CR tablets should not be chewed, crushed, dissolved, or broken.
Xanax:
- Xanax also has an FDA boxed warning.
Xanax should not be taken in combination with opioid pain relievers because of an increased risk of extreme sedation, severe respiratory depression, coma, or death. If the combination of a benzodiazepine and opioid cannot be avoided, the patient should be prescribed the lowest dose for the shortest period of time and must be closely monitored. Patients should not drive or operate machinery until effects are known.
- Xanax may cause dependence—the risk increases with higher doses, longer duration of use, and/or a history of drug or alcohol abuse. If you take Xanax, take the medication only as prescribed, and do not take additional doses.
- Keep Xanax out of the reach of children and others. Keep under lock and key if possible.
- Xanax should be used as a short-term treatment. When discontinuing Xanax, it should be slowly tapered to avoid withdrawal symptoms. Patients with seizure disorders are at higher risk for withdrawal symptoms. Your prescriber can provide you with a tapering schedule.
- There is a risk of suicide in patients with depression. Patients with depression should also be treated with an antidepressant and should be closely monitored.
- Xanax should be used with caution in patients with breathing problems such as COPD or sleep apnea.
- Use Xanax with caution and/or use lower doses in patients with severe liver problems.
- Xanax should not be used in pregnancy because of the risk to the fetus. If you are taking Xanax and find out that you are pregnant, consult your doctor immediately.
Both Ambien and Xanax are on the Beers’ List (drugs that may be inappropriate in older adults). There is an increased risk of cognitive impairment, delirium, falls, fractures, and motor vehicle crashes in older adults when Ambien or Xanax is used.
Frequently asked questions about Ambien vs. Xanax
What is Ambien?
Ambien is a sedative-hypnotic medication. It is also known by its generic name of zolpidem. It is used as a short-term treatment for sleep. It is approved by the FDA and because of its abuse potential, it is a controlled substance.
What is Xanax?
Xanax, also known by its generic name, alprazolam, is a benzodiazepine drug used to treat anxiety and panic disorder. Other drugs in the benzodiazepine category of medications that you may have heard of include Valium (diazepam), Ativan (lorazepam), Dalmane (flurazepam), Restoril (temazepam), Klonopin (clonazepam), and Halcion (triazolam). All of these drugs are approved by the FDA and are controlled substances like Xanax.
Are Ambien and Xanax the same?
No. While people may mention these drugs in the same sentence, they are quite different. They are in different categories of medication and have different dosing, indications, and side effects. Ambien is prescribed for the treatment of insomnia, and Xanax is used for anxiety or panic disorder.
Is Ambien or Xanax better?
Studies do not directly compare the two drugs, because they are different categories of medication used for different indications. Ambien is a drug that is used to help with sleep, while Xanax is for anxiety and/or panic. Ask your healthcare provider if Ambien or Xanax is appropriate for you.
Can I use Ambien or Xanax while pregnant?
No. Ambien taken during the third trimester can cause respiratory depression and sedation in the neonate. Xanax may cause fetal abnormalities and should not be used during pregnancy.
If you are already taking Ambien or Xanax, and find out that you are pregnant, contact your healthcare provider for guidance.
Can I use Ambien or Xanax with alcohol?
No. Combining either Ambien or Xanax with alcohol is dangerous and can cause psychomotor impairment, respiratory depression, extreme sedation, coma, or even death.
What is stronger than Ambien for sleep?
Ambien is one of the most commonly prescribed sleep medications, and it is similar to several other prescription sleep medications such as Lunesta (eszopiclone) and Sonata (zaleplon). If Ambien is not working for you, consult your healthcare provider for medical advice. Many patients do well, instead, with an OTC (over-the-counter) dietary supplement called melatonin. Melatonin helps regulate the sleep cycle, is available without a prescription, and because it is not a controlled substance, it does not have the potential for abuse or dependence.
What drugs should not be taken with Ambien?
You should not drink alcohol while taking Ambien. Other drugs that cause CNS depression also interact with Ambien. See the above table of drug interactions. Ambien has many drug interactions, and there are too many to list them all. Consult your healthcare provider for a full list of drug interactions.
Can I take Ambien every night?
Ambien should be taken immediately before bedtime, just before getting into bed, when you have at least seven to eight hours to sleep. In clinical trials, Ambien was studied for up to four to five weeks. If you need to take it for longer than four to five weeks, consult your healthcare provider. Many patients do take Ambien for longer periods, but you should be closely monitored by your prescriber.
Is Ambien As Addictive As Xanax?
Ambien and Xanax both belong to a class of medications known as sedative-hypnotics which are used to induce and/ or maintain sleep. Sedatives and hypnotics are two classes of drugs that are also known as sleeping pills, tranquilizers, or sedatives. There are two main types of sedative-hypnotics, which include benzodiazepines and z-drugs. Every individual is unique and will have a somewhat distinct physiological response to ingesting Ambien and Xanax, respectively. Although some individuals may prefer the effects of one over the other, Ambien is considered a less addictive substance than Xanax.
Xanax Basics
Xanax, generically known as alprazolam is an anti-anxiety prescription medication that belongs to the subsection of sedative-hypnotics known as benzodiazepines. It is primarily used to treat panic attacks, anxiety disorders, excessive worry, and posttraumatic stress disorder (PTSD). Xanax is a central nervous system depressant that works by acting on certain neurotransmitters in one’s brain, specifically the GABA-A (gamma-aminobutyric acid-A). When Xanax binds to this receptor it elicits a calming effect as it slows down excessive brain activity and reduces feelings of panic and/ or stress. Xanax is fast acting, and typically begins working within one to two hours. According to the U.S. Food and Drug Administration (FDA) the average half-life, meaning the length of time the substance will remain in one’s system until the concentration in one’s blood has been reduced by half, of alprazolam “has been found to be about 11.2 hours (range: 6.3-26.9 hours) in healthy adults.” Xanax can be a highly effective medication when used properly and under the direct supervision of a medical professional. However, as is true with any medication, there are risk factors and potential side effects associated with taking Xanax. The United Stated Drug Enforcement Administration (DEA) classifies Xanax as a Schedule IV Substance, which are defined as “drugs with a low potential for abuse and low risk of dependence.” When abused, Xanax is known to be a drug with high addiction potential.
Ambien Basics
Ambien is a brand name medication; the generic form is known as zolpidem. It is used to treat certain sleep issues (e.g., insomnia). Ambien belongs to the subsection of sedative-hypnotics known as z-drugs. Ambien is also a central nervous system depressant and works similarly in one’s body to Xanax. Much like Xanax, Ambien has been classified by the DEA as a Schedule IV Substance. Ambien is not intended for long-term use; rather short treatment periods lasting one to two weeks long, or less are most common. The average half-life of Ambien is about 2.5 hours. When Ambien is taken exactly as directed, under strict supervision of a qualified medical professional, it can be a highly effective medication.
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Ambien vs Xanax for insomnia: differences and side effects
- Ambien and Xanax - the same thing?
- What are the possible side effects of Ambien?
- What are the possible side effects of Xanax?
- What is Ambien?
- What is Xanax?
- What drugs interact with Ambien?
- What medications interact with Xanax?
- How should I take Ambien?
- How should I take Xanax?
Are Ambien and Xanax the same thing?
Ambien (zolpidem) and Xanax (alprazolam) are used to treat insomnia.
Xanax is used off-label to treat insomnia; approved for the treatment of panic attacks and anxiety disorders.
Ambien and Xanax belong to different drug classes. Ambien is a sedative/hypnotic and Xanax is a benzodiazepine.
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What are the possible side effects of Ambien?
The total side effects of the amberi include:
- Drumstick,
- Dizziness,
- Weak place,
- Frightening,
- Feeling of narcotic intoxication,
- Fatigue,
- Loss of coordination,
- NOS congestion,
- irritation of irritation irritation nose,
- Dry mouth,
- Sore throat,
- Nausea,
- constipation,
- diarrhea,
- Disorders of the stomach,
- Headache,
- muscle pain,
- Consciousness,
- Insom,
- Euphoria,
- Ataxia (Problems with Balance) and ,
- Visual changes.
Tell your doctor if you have any unlikely but serious side effects of Ambien, including:
- memory loss, suicide, hallucinations, confusion, agitation, violent behavior or restlessness).
What are the possible side effects of Xanax?
The total side effects of the XANAX include:
- drowsiness
- Drizzle
- Refresh problems (insomnia)
- Problems with memory
- Bad balance or coordination
- Inadvertently
- Problems at ,000
- Diarrhea
- Constipation
- Increased sweating
- Headache
- Nausea
- vomiting
- Disorders of the stomach
- Blutched vision
- Changes in appetite or weight
- Swelling
What is Ambien?
Ambien (zolpidem) is a sedative/hypnotic used to treat insomnia.
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What is Xanax?
Xanax (alprazolam) is indicated for the treatment of anxiety disorders and the short-term relief of anxiety symptoms in adults. Xanax is also indicated for the treatment of panic disorder in adults with or without fear of places and situations that may cause panic, helplessness, or embarrassment (agoraphobia).
What drugs interact with Ambien?
Ambien may interact with other medicines that cause drowsiness or slow breathing (eg, cold medicines, pain relievers, muscle relaxants, and medicines for depression, anxiety, or seizures) or antidepressants.
Ambien may also interact with alcohol, chlorpromazine, itraconazole, ketoconazole, or rifampicin.
Symptoms of insomnia may also return after stopping Ambien. These symptoms may seem worse than before you started taking Ambien.
What medications interact with Xanax?
Xanax may interact with cold or allergy medicines, narcotic pain medicines, sleeping pills, muscle relaxants, depression or anxiety medicines, antibiotics, antifungal medicines, antidepressants, and barbiturates. Xanax may also interact with birth control pills, cimetidine, cyclosporine, dexamethasone, ergotamine, imatinib, isoniazid, St. John's wort, heart or blood pressure medicines, HIV/AIDS medicines, and anticonvulsants.
Do not take Xanax if you are allergic to alprazolam, other benzodiazepines, or any of the ingredients in Xanax. See the end of this medication guide for a complete list of Xanax ingredients. you are taking antifungal medicines, including ketoconazole and itraconazole.
Do not stop taking Xanax without talking to your doctor first, even if you feel well. If you suddenly stop taking Xanax, you may experience seizure attacks or unpleasant withdrawal symptoms.
How should I take Ambien?
The recommended adult dose of Ambien is 10 mg as regular tablets or spray or 12.5 mg as extended release tablets.
Does zantac work immediately in adults?
How should I take Xanax?
Take Xanax exactly as your doctor tells you to. Your health care provider will tell you how much and when to take Xanax. If you have taken too much Xanax, call your doctor right away or go to the nearest emergency room.
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Xanax is a benzodiazepine drug. Taking benzodiazepines with opioid medications, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, breathing problems (respiratory depression), coma, and death.
Xanax may cause drowsiness or dizziness and slow thinking and motor skills.
Do not drive, operate heavy machinery, or engage in other dangerous activities until you know how Xanax affects you.
Do not drink alcohol or take other drugs that may make you drowsy or dizzy while taking Xanax without first talking to your doctor. When taken with alcohol or drugs that cause drowsiness or dizziness, Xanax can make your drowsiness or dizziness much worse.
Do not take more Xanax than prescribed.
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Any drug information published on RxList.com regarding general drug information, drug side effects, drug use, dosage, etc. is from the original drug documentation contained in his FDA drug monograph.
The drug information contained in the drug comparisons published on RxList.com is primarily derived from the FDA drug information. The drug comparison information contained in this article does not contain data from human or animal clinical trials conducted by any of the drug manufacturers comparing drugs.
The drug comparison information provided does not cover all potential uses, warnings, drug interactions, side effects, adverse or allergic reactions. RxList.com is not responsible for the health care provided to a person based on the information posted on this site.
Because drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the fact that drug information is time dependent, RxList.com makes no guarantee that the information provided is the latest.
The absence of drug warnings or information does not in any way guarantee the safety, efficacy or absence of side effects of any medicine. The medication information provided is for reference only and should not be used as a substitute for medical advice.
If you have specific questions about a drug's safety, side effects, uses, warnings, etc., you should ask your doctor or pharmacist or refer to specific drug details found on the FDA websites. gov or RxList.com for more information. .
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You can also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or by calling 1-800-FDA-1088.
References Medical Editor: John P. Cunha, DO, FACOEP
List of medicines, preparations and substances that are prohibited from being imported into Russia
The media often write about criminal cases initiated for the importation of medicines into Russia from abroad. It seems like this only happens to drug lords. But in reality, both strong painkillers and ordinary tea for weight loss can attract the attention of the customs service with equal success.
Before checking in your suitcase with a first aid kit in your luggage or placing an order for a medicine or dietary supplement in a foreign online store, we advise you to carefully read the law "On the Circulation of Medicines" and study the composition of the drugs included in your first aid kit. So you can check if you own substances from the list of banned substances in Russia.
We have compiled a list of drugs banned in Russia, after the import of which Russians most often have problems with the law.
Tramal
Solution for injection, tablets, capsules
When used: for pain relief in cancer patients, in the postoperative period, for injuries, for pain due to myocardial infarction, for painful medical procedures
Import into Russia: prohibited
Why banned: contains tramadol, an opioid narcotic analgesic. The law also prohibits the importation of other opioids, such as morphine, heroin-containing drugs
Bupropion
Tablets
When used: for depression, for the prevention of its exacerbations and relapses, as well as for the treatment of nicotine dependence
Improvement to Russia: Bupropion is not in the list of prohibited substances, but policies and customs are called the Russian Federation its “derivative of a narcotic substance” and are being tried for its purchase
Why is prohibited: the active substance buproprion is a derivative of ephedron, a substance of the group of psychostimulants banned in Russia
Meridia
Capsules
When used: for losing weight and treatment of obesity
Improve for Russia: Listenced
Why is prohibited: Sibutramin - derivative of amphetamine, enhancing saturation. The law prohibits the importation of other drugs containing sibutramine, as well as some Chinese slimming teas containing sibutramine
Caffetin
Tablets
When applied: for headache and toothache, migraine, neuralgia, pain in muscles and joints, for painful medical and diagnostic procedures, as well as after injuries
Import to Russia: is restricted. Can only be carried for personal use with a certificate or prescription from a doctor. You need to fill out a customs declaration
Why is prohibited: contains codeine. Such drugs in Russia are dispensed by prescription
Dinitrophenol (DNP)
Capsules
Use: for wood preservatives and pesticides, textile dyeing. In some countries, it is illegally used as a metabolic stimulant - in a simple way, a fat burner
Import to Russia: banned
Why banned: is a highly toxic drug, included in the list of potent substances. The law prohibits the importation of any preparations containing DNP
Retabolil
Injection solution
When used: for building muscle mass
Import to Russia: banned
Why banned: the active ingredient is nandrolone, an anabolic steroid. The law prohibits the import of any anabolics into Russia. Retabolil is also included in the World Anti-Doping Code prohibition list, which is updated every year
Zolpidem
Tablets
When applied: for sleep disorders - insomnia or early morning and night awakenings
Import to Russia: is restricted. Can only be carried for personal use with a certificate or prescription from a doctor. You need to fill out a customs declaration
Why is prohibited: is on the list of psychotropic substances. Restrictions apply to all drugs containing zolpidem
Some smoking mixtures
When used: as a recreational activity
Import into Russia: prohibited
Why banned: Smoking blends often contain banned substances: e. g. sage sage leaf (Salvia Divinorum), Hawaiian rose seed (Argyreia Nervosa), blue lotus flower and leaf (Nymphea Caerulei)
Modafinil
Tablets, capsules
When used: to stimulate brain activity, relieve stress and treat drowsiness
Import to Russia: banned
Why banned: Modafinil is on the list of narcotic and psychotropic substances
Cannabidiol (CBD, CBD)
Tablets, lozenges, chewing gum, cream, oil, capsules, patches, liquid for electronic cigarettes and vapes, etc.
When used: pain in muscles and joints, with migraine and anxiety, with epilepsy, parkinsonism and post-traumatic stress disorder
Import to Russia: prohibited
Why prohibited: the law prohibits the import of cannabidiol and other cannabis derivatives
There are no recommendations for taking medications in this article.
