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Xanax and trintellix


Trintellix And Xanax: Is There Any Interaction?

In this blog post, we are going to talk about the possible interactions between Trintellix and Xanax. We will also talk about the safety and efficacy of the concomitant use of these two prescription medications. 

This blog will also help you understand how to use Trintellix and Xanax properly and what are the possible dangers associated with the combination therapy. 

Is there any interaction between Trintellix and Xanax? 

There is no known interaction between Trintellix and Xanax, but it does not mean that an interaction can not occur. Every single medication reacts with your body as well and if your physiological composition responds negatively to the combination of Trintellix and Xanax then you may suffer from some side effects. 

However, it is impossible to predict any interaction. The only way to find out which combination works best for you is to try them out. If you feel any unusual side effects after taking these two meds together, make sure you immediately report to your healthcare provider.  

Antidepressants and anti-anxiety medications can react inevitably in some people or some underlying health conditions. A possible drug interaction should not be an only concern. Meds can interact with diseases as well. 

This is exactly why such warnings are mentioned on the leaflets of every single medication to help prevent drug-disease interactions as much as possible. It is also extremely important to stick to your doctor recommended dose. 

Both Trintellix and Xanax affect your brain and it is extremely important to make sure you’re taking them right. When anti-anxiety and antidepressants are combined together, the dose is usually adjusted. 

Can Trintellix and Xanax make a good combination? 

Trintellix and Xanax can make a good combination and it may help with some of the following conditions:

It may help control your anxiety 

The combination of Trintellix and Xanax can be a good one to control anxiety or panic attacks. It is a well known fact that antidepressants do not work overnight.  

You have to give these meds at least 3 to 4 weeks to kick in and start managing your depression or any other mental health condition for which you’re taking them. However, antidepressants can start causing side effects way earlier. 

One of the most common early side effects of antidepressants is anxiety. That’s where Xanax comes into the picture. Xanax can help control the early anxiety caused by Trintellix. 

However, it is not suitable to continue using Xanax for a long time as it is a short acting benzodiazepine and can cause addiction in people who tend to misuse medications. Usually Xanax should be used as long as your antidepressant kicks in. 

It may help manage your Insomnia 

The combination therapy with Trintellix and Xanax can help manage insomnia. Some antidepressants also cause sleep disturbances in the early course of the treatment. The funny thing is it may not cause insomnia in everyone. 

Some people respond so well to antidepressants that these meds become life-saviours for them. However, some people get scarred for life. 

This is exactly why I can’t tell you if this combination would work at all for you, but I can tell you for sure that this is something you should never do with proper diagnosis and your doctor’s recommendation. 

It may be a good treatment option for major depressive disorder (MDD) 

The combination of antidepressants and benzodiazepines are well known for their beneficial effects in the treatment and management of major depressive disorder (MDD) or treat-resistant depression. 

Some studies indicate that Xanax itself can control depression. A 1988 study monitored the antidepressive effects of xanax (alprazolam) and observed six case studies, four of which showed great outcomes, similar to those of Tricyclic antidepressants (TCAs), but with less side effects. 

This indicates that xanax itself possesses antidepressant properties but the mechanism through which it works to counteract the symptoms of depression is still unknown. It is also not suitable to use this med for a long time. However, a few weeks of combination therapy of Trintellix and Xanax can deliver fruitful results. 

What are the side effects associated with the use of Trintellix and Xanax? 

Both Trintellix and Xanax are associated with some side effects, because meds without possible side effects? Not possible. It may not cause any side effects in you or me, but it can severely affect someone else. 

Side effects of Trintellix 

Trintellix is associated with a number of side effects. These include:

  • Headache 
  • Nausea 
  • Diarrhoea 
  • Vomiting 
  • Flatulence 
  • Fatigue 
  • Abdominal pain 
  • Xerostomia or dry mouth 
  • Nightmares 
  • Dizziness or lightheadedness 
  • Loss of libido in both male and females. Males may suffer from inability to ejaculate, while females may suffer from inability to have an orgasm. 

Some serious and rare side effects include:

  • Allergic reaction associated with symptoms like redness of skin, itching, burning sensation, blisters, blue-purple patches, tightness of chest, wheezing, difficulty in breathing, hoarseness etc.  
  • Swelling or tenderness in different parts of the body.
  • Dementia 
  • Difficulty in concentrating 
  • Excessive sweating 
  • Fever with chills 
  • Hallucinations
  • Convulsions 
  • Blackouts 
  • Coma

Side effects of Xanax 

Xanax is also associated with some side effects. These include:

  • Dizziness
  • Tiredness or fatigue 
  • Drowsiness 
  • Muscle pain
  • Vision problems 
  • Headache 
  • Hypersomnia 
  • Forgetfulness 
  • Troubled or intrusive thoughts
  • Impairment of motor coordination 
  • Constipation or diarrhoea 
  • Nausea 
  • Vomiting 
  • Dementia 
  • Depression 
  • Abnormal behaviour
  • Blackouts 
  • Serious respiratory depression which lowers down breathing rate and can decrease the availability of oxygen in the blood. It could be life-threatening for people suffering from asthma or chronic obstructive pulmonary disease (COPD) 

What are the risks associated with the use of Trintellix and Xanax? 

Trintellix and Xanax may cause some serious complications in some people. Trintellix is one of those antidepressants which are associated with a black-box warning. It can induce suicidal behavior in users younger than 24 yesrs of age. 

They may start showing signs of self-harming behaviour. It is absolutely necessary to keep an eye on such people, especially when they are new users and they don’t know how Trintellix makes them feel. 

Trintellix can also cause some cardiac side effects in people who are living with some cardiovascular disease. However, it may not affect every heart patient, but precautions are necessary to make sure it doesn’t affect your pre-existing health condition. 

Use of Trintellix in children may not be suitable, especially children younger than 18 years of age as the drug has not been tested on people of such age group. There are a lot of other safer options that you can go for. 

As far as adults are concerned, it may cause some mood disturbances, especially during the first few months of the treatment. Adults can become suicidal as well and they may suffer from enhanced depression for a little while.  

Trintellix may not work for everyone. When an antidepressant does not work, your mental health condition starts deteriorating even more and this is the biggest sign of therapeutic failure. People may also start having panic attacks and they may start worrying over small matters. 

Make sure you inform your doctor if you’re pregnant or trying to get pregnant before using Trintellix. You should also inform your doctor if you’re a breastfeeding mother. 

Xanax is also associated with some important warnings. The proper use of these benzodiazepines is crucial because of its shorter duration of action. The effects of Xanax start to wear off in around 8 to 10 hours. 

This makes people want to take this medication again because of the calming effects it produces. It causes muscle relaxation and makes you feel at peace. 

Xanax should be used carefully in pregnant women. Several research studies have revealed that excessive use of Xanax, especially during the third trimester can cause fetal defects. It may also cause some addictive effects in the new born baby. 

Xanax should be used cautiously by breastfeeding women as it can be passed to the baby through breastmilk and may cause some disturbing side effects in the young one. 

Xanax is contraindicated to be used in patients with major respiratory illnesses. This is because it is capable of causing respiratory depression and it can lead to life threatening complications for people suffering from asthma or chronic obstructive pulmonary disease (COPD), especially at higher doses. 

Make sure you use this combination only when it is absolutely necessary. Do not engage in certain activities right after taking these meds together, especially if you’re a new user and you don’t know how this combination makes you feel. 

Conclusion 

In this blog post, we have discussed the concomitant use and safety and efficacy of Trintellix and Xanax. We have also looked at their basic uses and how these meds usually work. This blog has also covered some reasons why this combination could be a good option.  

One thing to bear in mind is that not every combination of meds work in the exact same way for every individual. Some people may not be able to bear this combination, while some other people may gain wholesome benefits for it. 

Make sure you only use meds in combination when prescribed by your healthcare provider. Always stick to your doctor’s recommended dose and frequency. Self medication is not something you should try and you should change your dose on your own.

FAQs: trintellix and xanax

Can you take Xanax while taking Trintellix?

You can take Xanax while taking Trintellix, but only if recommended by your healthcare provider. Trintellix and Xanax may not interact with one another, but it does not mean that an interaction is not possible.

Every single medication reacts with your body as well and if your physiological composition responds negatively to the combination of Trintellix and Xanax then you may suffer from some side effects. However, it is impossible to predict any interaction.  

What can you not take with Trintellix?

  • Monoaminoxidase inhibitors (MAOIs). The combination use can increase the risk of serotonin syndrome. 
  • Non-steroidal anti-inflammatory drugs (NSAIDS). The combination use can increase the risk of bleeding. 
  • Pimozide. The concomitant use can increase the plasma concentration(availability of a drug in the blood) of pimozide to much higher levels. It can result in life-threatening arrhythmia.
  • Controlled substances, including all narcotic analgesics. The concomitant use can cause severe psychological side effects. 
  • Mood stabilisers 
  • Alcohol 

Can you take antidepressants while on Xanax?

Yes, you can take antidepressants while being on Xanax. In fact, the combination of Xanax and safer antidepressants like selective serotonin reuptake inhibitors (SSRIs) is usually considered a good option to help manage anxiety and insomnia till your antidepressant kicks in. However, the combination is usually short lived and Xanax is discontinued when the antidepressant starts working.  

Is Trintellix good for severe anxiety?

Trintellix is not yet approved by the Food and Drug Administration (FDA) for the treatment of anxiety. However, it can be used off label, but there are plenty other approved and effective medications that can be used to treat severe anxiety. 

What drugs should not be taken with alprazolam?

  • Antifungals and antivirals. They may inhibit the metabolism of clonazepam and cause toxicity. 
  • Antiepileptics. The concomitant use may decrease the beneficial effects of clonazepam. 
  • Anti-allergy medications. The concomitant use increases the risk of sedation 
  • Narcotic analgesics or any other controlled substance. The concomitant use can cause serious CNS side effects. 
  • Sleeping pills
  • Other anxiolytics and tricyclic antidepressants (TCAs). 

References

  • Trintellix and Xanax drug interactions – a phase IV clinical study of FDA data https://www.ehealthme.com/drug-interaction/trintellix/xanax/
  • Drug Interactions between Trintellix and Xanax https://www. drugs.com/drug-interactions/trintellix-with-xanax-3490-18003-133-54.html
  • National Library of Medicine – Vortioxetine https://medlineplus.gov/druginfo/meds/a614003.html 
  • M D Warner et al. J Clin Psychiatry. (1988) – Alprazolam as an antidepressant https://pubmed.ncbi.nlm.nih.gov/3281931/ 
  • Nassima Ait-Daoud, MD, Allan Scott Hamby, MD, and Derek Blevins, MD (2018) – A Review of Alprazolam Use, Misuse, and Withdrawal https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846112/#__ffn_sectitle 

Is Trintellix (vortioxetine) good for anxiety disorders?

Trintellix is FDA approved to treat depression but is sometimes prescribed off-label to treat anxiety

Trintellix is a prescription antidepressant that’s FDA approved to treat major depressive disorder (MDD). It works by balancing levels of the neurotransmitter serotonin, which plays an important role in mood, emotions, and appetite. Because serotonin is believed to help regulate anxiety, Trintellix is also sometimes used off-label to treat anxiety. Let’s take a more in-depth look at taking Trintellix for anxiety. 

Does Trintellix work for anxiety?

Trintellix is one of the brand-names of the generic medication vortioxetine, which belongs to a group of medications called selective serotonin reuptake inhibitors (SSRIs). Trintellix used to be called Brintellix, but it was renamed in 2016 because it was frequently getting confused with an antiplatelet medication called Brilinta. Renaming the medication to Trintellix has helped minimize confusion in doctors and patients. 

Trintellix is an SSRI that can help improve a person’s mood, emotions, and sleep patterns. The Food and Drug Administration (FDA) has only approved Trintellix to treat major depressive disorder, but it can be prescribed off-label to treat anxiety.

Off-label prescribing happens when a doctor prescribes a patient a medication that’s FDA approved to treat a condition that’s different from what the patient has. This is a common occurrence that’s completely legal to do, and it’s estimated that about 1 in 5 prescriptions are actually off-label prescriptions.  

So a doctor can write someone with anxiety a prescription for Trintellix, but why might they do this when there are so many other anti-anxiety medications on the market? Trintellix blocks serotonin reuptake like other SSRIs, but unlike other antidepressants, it also has agonist and antagonistic effects on the 5-HT1A and 5-HT3 serotonin receptors in the brain. Researchers aren’t exactly sure how this works, but they believe it contributes to the antidepressant effects of Trintellix.        

Studies have shown that Trintellix improves symptoms of generalized anxiety disorder more than a placebo and that it is effective and tolerable in patients with severe anxiety. A meta-analysis study published in the Current Drug Targets journal found that Trintellix is effective for people with anxiety disorder with only mild to moderate side effects. Overall, it has proven to be effective at reducing anxiety and depression symptoms for people with major depressive disorder or high levels of anxiety.       

Starting Trintellix for anxiety

Starting any new medication can be stressful, and if you already have anxiety, then knowing what to expect when you start taking Trintellix can help make the process easier. One of the most important things to be aware of when you first start taking Trintellix is that it isn’t a fast-acting medication. It may take some time before you start to see your anxiety symptoms get better. It can take two to four weeks (or longer) to feel the full effects of Trintellix.

Dosage

Trintellix is available as an immediate-release tablet in three dosage strengths: 5 mg, 10 mg, and 20 mg. The usual starting dose of Trintellix is 10 mg taken once per day with or without food. This dosage may be increased to 20 mg per day or decreased to 5 mg per day depending on how the drug is working or any side effects experienced. 

The exact amount of Trintellix that you’ll need to take and how long you’ll need to take it will vary based on your individual symptoms and medical history. Taking higher doses or more than one dose of Trintellix in an attempt to make it work faster isn’t safe and may cause side effects. This is why it’s important to talk with your healthcare provider about the appropriate dosage for managing your anxiety. If you’ve taken too much Trintellix you should call your doctor or the Poison Control Center at 1-800-222-1222. They will be able to advise you on whether or not you should visit an emergency room or urgent care center.     

Interactions

Trintellix shouldn’t be taken at the same time as certain medications because of potential drug-drug interactions. It shouldn’t be taken within two weeks of taking: 

  • Monoamine Oxidase Inhibitors (MAOIs)
  • Methylene blue
  • Linezolid 

Trintellix shouldn’t be taken within two weeks of taking a monoamine oxidase inhibitor (MAOI), and an MAOI shouldn’t be taken within 21 days of stopping Trintellix because of a heightened risk of experiencing serotonin syndrome. Serotonin syndrome is a potentially life-threatening condition that happens when too much serotonin builds up in the body. Symptoms of serotonin syndrome include shivering, tremors, high blood pressure, rapid heart rate, confusion, muscle rigidity, and seizures.  

You should tell your doctor if you’re taking any of the following medications as well, because they may affect how Trintellix works or increase the risk of side effects: 

  • Other depressants
  • Antipsychotic medications 
  • Over-the-counter pain medications like NSAIDs or aspirin 
  • Blood thinners like Coumadin (warfarin)
  • Triptan medicines or tryptophan supplements
  • Diuretics
  • St. John’s Wort
  • Carbamazepine 
  • Fentanyl 
  • Lithium 
  • Phenytoin 
  • Quinidine
  • Bupropion 
  • Buspirone  
  • Rifampin 
  • Tramadol 

Side effects

When you first start taking Trintellix, you may experience some possible side effects. Some people may experience feeling restless or energized soon after taking a dose, which could lead to trouble sleeping. Here are some other common side effects that people experience when they start taking Trintellix:

  • Nausea
  • Vomiting
  • Constipation
  • Diarrhea
  • Dry mouth
  • Muscle stiffness 
  • Gas 
  • Weight gain 
  • Abnormal dreams 
  • Eye pain
  • Vision changes
  • Dizziness
  • Sexual dysfunction   

It’s important that you avoid missing a dose of Trintellix to ensure treatment remains consistent and decreases the risk of relapse in depressive symptoms. If you do miss a dose it’s best to take your next dose as soon as you remember, unless it’s almost time to take your next dose. Doubling up on doses can cause side effects and, in rare cases, may cause serotonin syndrome. Many healthcare providers will recommend taking Trintellix at approximately the same time every day.   

Although it’s rare, Trintellix can cause more serious side effects that may require medical attention. The FDA label for Trintellix contains a boxed warning for potential suicidal thoughts and behaviors, especially in children, adolescents, and young adults. If you’re taking Trintellix and start to have any suicidal thoughts or behaviors, you should seek medical help right away.

Trintellix can also cause serious side effects like:  

  • Unusual bleeding
  • Unusual bruising
  • Mania or hypomania in people with bipolar disorder
  • Angle closure glaucoma
  • Low sodium levels in the blood (hyponatremia)

If you experience any of these side effects while taking Trintellix you should talk with your healthcare provider as soon as you can. If you are allergic to vortioxetine or any of the other ingredients in Trintellix should avoid taking the medication because it may cause allergic reactions.  

Restrictions

People with bipolar disorder should take Trintellix only if approved by their doctor because it may cause manic episodes. People with glaucoma and bleeding disorders should only take Trintellix under the supervision of a doctor since it may increase the risk of bleeding episodes and worsen closed-angle glaucoma.  

Certain medications are unsafe for elderly patients, but Trintellix has been shown to be tolerable and safe for adults older than 65 years old. Clinical studies have shown no difference in safety or efficacy between older adults and younger adults, and there has been no noticeable difference in response to the medication between older and younger adults either. Trintellix is not approved for any patients under the age of 18. 

Trintellix may affect the fetus in pregnant women. Taking Trintellix in the third trimester of pregnancy may lead to an increased risk of a condition called persistent pulmonary hypertension in newborns. There’s no data on Trintellix and how it affects breast milk or breastfed infants, which is why it’s important to weigh the benefits and risks of using the medication while breastfeeding with a healthcare provider.       

What is the most effective antidepressant for anxiety?

There isn’t one medication that is most effective at treating anxiety. What works for one person may not work for another, but the good news is that there are many different types of antidepressants that can treat mental health conditions like anxiety. In addition to SSRIs, here are some other categories of antidepressants:  

  • Serotonin and norepinephrine reuptake inhibitors (SNRIs): increase the availability of serotonin and norepinephrine in the brain.
  • Tricyclic antidepressants: increase levels of serotonin and norepinephrine in the brain and block acetylcholine. 
  • Monoamine oxidase inhibitors (MAOIs): prevent the enzyme monoamine oxidase from removing dopamine, serotonin, and norepinephrine from the brain.  

Here are some of the most effective antidepressants for anxiety.   

Atypical antidepressant. Russian Woman Faces Jail for Ordering Non-Prohibited Medicine

  • Daria Napeeva
  • BBC

Image copyright, Getty Images

A criminal case has been opened in Yekaterinburg against a girl who ordered a package of antidepressants from a foreign online pharmacy. Now she faces up to 20 years in prison for the acquisition and smuggling of drugs on a large scale. nine0018

24-year-old Darya Belyaeva was detained on April 8 at the exit of the post office. According to the Ural Customs Service, the package she received "contained 30 tablets containing the narcotic drug ephedron" with a total weight of 10.6 grams.

This substance is said to be used by drug addicts to stimulate the adrenergic system (the receptors that produce adrenaline and norepinephrine).

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Ephedron (methcathinone) is a strong homemade stimulant of the central nervous system and banned in most countries, including Russia. Among drug users, he is also known as "mulka" and "jeff".

As lawyer Irina Ruchko told the BBC Russian Service, Daria Belyaeva is registered with a psychiatrist with a diagnosis of schizotypal personality disorder. Now the girl is under house arrest. The antidepressant she ordered by mail from Poland is called bupropion. nine0011

Not banned

This drug cannot be sold in Russian pharmacies because it does not have a pharmacological registration, but it is not a banned drug.

"The prescribed drugs did not help, the attending physician said that there is a drug bupropion that can help. Daria read about it on the Internet, made inquiries, concluded that this substance is not prohibited for circulation in Russia, ordered it on the official website in Europe, where the drug is produced and allowed for circulation. She could not and should not have known that this substance may contain some ephedron derivatives in its composition, "says the defender. nine0011

"According to Daria, several people previously ordered this drug in a similar way and received it successfully. There were no claims from the customs authorities against them," lawyer Irina Ruchko said.

Darya Belyaeva herself confirmed to the BBC that she decided to try bupropion because the antidepressants she was taking on prescription did not help her fully.

"Conventional SSRIs [Selective Serotonin Reuptake Inhibitors], which basically treat everyone, do not help me as they should - they do not relieve severe fatigue, lethargy, apathy and 13 hours of sleep. There are also tricyclic antidepressants, but they are quite old, they have a lot of severe "side effects" in somatic terms. I have experienced them myself and don't want any more, - said Daria Belyaeva, - I decided to try [bupropion], because I have been very, very bad for quite a long time, and I just want to improve of his condition." nine0011

Legal uncertainty

Bupropion is not on the list of restricted substances in Russia. However, as stated in the conclusion drawn up by an expert of the customs administration, it is a derivative of ephedrone, which is included in the list of prohibited substances.

Bupropion and ephedron have a similar structure and both belong to the class of phenethylamines, but ephedron cannot be obtained from bupropion itself, Alexander Polezhaev, candidate of chemical sciences, senior researcher at INEOS RAS, told the BBC. nine0011

Image copyright, Getty Images

Photo caption,

Bupropion molecule

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The FCS-requested expert report states that bupropion is a derivative of ephedron, citing a note that was added to the list of controlled psychotropic substances in Russia in 2012. nine0011

The concept of "derivatives of narcotic drugs and psychotropic substances" established in it is based on the mechanism of the so-called "formal substitution" of hydrogen atoms, halogens or hydroxyl groups in the chemical structure of a known narcotic substance, in which the total number of carbon atoms in the resulting substance should not exceed their quantity in the "original substance".

Professional chemists criticize this approach because it does not take into account significant changes in the biochemical and psychoactive properties of substances, which, as a rule, are observed when "formal substitution" of one or more atoms. nine0011

"Formal substitution" does not guarantee the similarity of the biochemical properties of the original substance and its derivative, explains Dmitry Gladyshev, head of the Versiya independent expert bureau. If you follow the definition of the government, then it turns out that, for example, fluoroacetic acid (CH2FCOOH) is a derivative of acetic acid (CH3COOH), since it has one hydrogen atom formally replaced by one fluorine atom. But in fact, the first is a highly toxic poison, and the second is a practically harmless substance widely used in the food industry and cooking. nine0011

According to Gladyshev, one should look not at how many hydrogen atoms and which ones are replaced in a controlled substance, but at what psychoactive and physico-chemical properties the substance has and whether it reproduces the effect of a known drug.

Image copyright, Getty Images

Image caption,

Ephedron molecule

"There are a lot of legal grounds for saying that this substance [bupropion] is not controlled at all in the Russian Federation, and by and large, if a person did not know that this substance has psychoactive properties and did not specifically take it for narcotization and obtaining psychoactive effects, he cannot have intent to circulate such substances. And there should be no questions for him, "Gladyshev believes. nine0011

What is this antidepressant

Bupropion is an atypical antidepressant. Unlike the commonly prescribed SSRI antidepressants, which rely on serotonin reuptake, bupropion affects dopamine and norepinephrine. The drug has been on the market for over 30 years and is the fourth most commonly prescribed antidepressant in the US, with more than 23 million prescriptions in 2016.

In Russia, bupropion, produced by the British company GlaxoSmithKline, was registered in 2010 under the trade name Wellbutrin. According to information from the state register of medicines, six years later, its registration was canceled. As follows from the documents of the Ministry of Health, this decision was made on the basis of a statement from the Russian pharmaceutical company Akrikhin JSC. The BBC did not respond to inquiries. nine0011

In world practice, bupropion is used for various forms of depression, bipolar disorder, attention deficit disorder, nicotine addiction, as well as to enhance the effect of other antidepressants and correct drug-induced sexual disorders.

"It is well tolerated, does not increase or even reduce weight, does not impair sexual function, has a stimulating effect, which is important for many patients with depression," says psychiatrist, narcologist Dmitry Frolov. nine0011

According to psychiatrist Pavel Alfimov, bupropion is usually prescribed when a patient has symptoms such as hypersomnia (excessive sleep) and hyperphagia (overeating), and it also works well for anxiety and atypical depression. In a number of countries, bupropion is prescribed not even by psychiatrists, but by general practitioners, Alfimov notes.

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Both specialists told the BBC that bupropion has established itself as a fairly safe and non-addictive drug. "Its addictive potential is rather casuistry. It does not cause such physical dependence as, for example, phenazepam, Xanax or alcohol and cigarettes," says Alfimov.

Psychiatrists have also confirmed that bupropion can be prescribed to patients with schizotypal personality disorder, like Darya Belyaeva, to treat concomitant depressive symptoms, which are quite common. “With schizotypal disorder, there can be depression, it can be severe and persistent. There are a lot of people for whom SSRIs are poorly suited, for such people bupropion is the drug of choice,” says Alfimov. nine0011

The doctor says that he often sees patients who take or used bupropion, despite the fact that it is not available in Russian pharmacies, some of them were prescribed it abroad. Patients also told Dmitry Frolov about the successful experience of self-treatment with bupropion and the problems associated with its purchase.

As Alfimov notes, despite the pronounced stimulating effect, bupropion is not suitable for recreational consumption: "When using bupropion, one almost never encounters the effect of euphoria, high... Of course, citizens experiment, but it is completely useless." nine0011

Photo author, easyfarma.cl

Photo caption,

Daria Belyaeva bought bupropion under the trade name Elontril

"It's not a drug, it's a well-studied medical drug. Currently, tens of millions of people get it, and these are not consumers drugs, not stimulant addicts. These are people with depression, people who are trying to quit smoking, those who are trying to reduce excess weight and cure sexual dysfunction. This is not a panacea, but there are people for whom it can improve the quality of life," concludes Alfimov. nine0011

"I often feel the need to prescribe such a drug, especially considering that psychostimulants, which are used to treat apathy and drowsiness in depression, in ADHD, are prohibited here. But alas, Russian drug policy sometimes frankly interferes with the treatment of mental disorders," says Frolov .

The doctor suggests that the manufacturing company GlaxoSmithKline could refuse to renew the registration of the drug in Russia, deciding "not to get involved in possible problems with the harsh Russian drug policy." nine0011

According to Alfimov, the lack of bupropion on the Russian market may be due to commercial reasons - the drug is quite cheap, and to enter the market, the manufacturer needs to invest serious resources, and only large corporations can afford this.

Will there be drugs in Russia in 2022 and what will happen to antidepressants and other psychotropic drugs

Daniil Davydov

medical journalist

Author profile

We asked psychotherapist Sergei Divisenko to talk about which psychotropic drugs may disappear or become more expensive in the very near future.

The result is a list of drugs, some of which are produced only abroad - most likely, difficulties with them will arise in the near future due to problems with delivery, and funds that, most likely, will not disappear and will not rise in price. These are drugs that have generics that are produced either in Russia or in countries that have not joined the sanctions - for example, India. nine0011

What is important to know about psychiatric drugs

In psychiatry, five groups of drugs are most commonly used.

Tranquilizers. Strong sedatives that depress the central nervous system. They are prescribed for anxiety, acute stress reactions, panic attacks.

Antipsychotic drugs: from "basic tranquilizers" to neuroscientific nomenclature - "Psychological medicine"

Antidepressants. nine0064 Drugs that normalize the level of neurotransmitters - chemicals through which the nerve cells of the brain exchange information. Antidepressants are given to people with a deficiency or excess of neurotransmitters to relieve symptoms of depression, obsessive-compulsive disorder, generalized anxiety disorder, post-traumatic stress disorder, and bipolar affective disorder.

What are antidepressants - a textbook for medical students StatPearls

Normotimics, or mood stabilizers. A group of medicines used to treat bipolar disorder.

What are Mood Stabilizers - Medscape Medical Guide

Antipsychotics, or neuroleptics. These drugs either temporarily disable neurotransmitter receptors or bind to receptors instead of neurotransmitters, canceling their action. They are typically used to treat schizophrenia or other psychotic disorders, they are also used to treat bipolar disorder, and sometimes to enhance the effects of other medications in the treatment of depression or anxiety. nine0011

What are antipsychotics - StatPearls

What are Z-hypnotics - Journal of the American Medical Association

Sleep aids. This group includes drugs with a different principle of action - both Z-hypnotics, which have a powerful hypnotic effect, similar to tranquilizers, and light hypnotics - for example, melatonin.

How to deal with insomnia

In addition to these main groups, other drugs are used in psychiatry - for example, the drug Strattera, which is designed to treat attention deficit hyperactivity disorder, or ADHD, in children and adults. nine0011

Some psychiatric drugs are new and only produced by overseas companies. Such a medicine can only be replaced by an analogue - a medicine with a different active substance that has a similar effect on the body. Only the attending physician can select such a replacement.

/list/adhd-in-school/

Crop Drawings and Fractional Problems: 7 Techniques to Help Me Learn with ADHD announced its withdrawal from the Russian market. So far, supplies to Russia have been partially limited only by the American company Eli Lilly - it has refused to supply the drug Cialis for the treatment of erectile dysfunction. nine0011

However, most drugs have been on the market for a long time, so they have generics - drugs with the same active ingredient that are produced by other manufacturers, including Russian ones.

Prices for drugs vary among different network pharmacies and may increase in the near future

Is it possible to replace original imported drugs with Russian generics

Sergey Divisenko

psychotherapist

In most cases, replacing the original drug with a generic will not affect the quality of treatment . At the same time, it is important to understand that approximately 90% raw materials for Russian generics are not produced in our country, but are brought from other countries - India, China, Hungary, Poland. If due to logistical problems there are interruptions in the supply of the active substance, there may be problems with the production of Russian drugs, too. It is believed that stocks of the active substance at Russian pharmaceutical factories will last for about six months. Therefore, the prices of generics have already risen — and most likely will continue to rise in the future.

It is possible that after some time even a Russian generic will cost more. Therefore, I advise my patients to stock up on medications that they take regularly in order to save money. The drugs taken regularly are mood stabilizers, antidepressants and antipsychotics - they can be purchased for 3-6 months. nine0011

But this does not apply to tranquilizers and some sleeping pills, that is, drugs that, as a rule, lose their effectiveness over time. And tranquilizers can be addictive, so taking them for a long time is not recommended. If you are taking a drug from these groups, it is enough to make a supply for 1 month.

How to track the availability of medicines

The Mental Health telegram channel talks about drug shortages and their return to pharmacy chains. Strictly controlled drugs, which are prescribed only on special prescriptions, can be searched on the website aptekamos.ru. Despite the name, the site shows pharmacies that have the necessary medicine throughout the country, and not just in Moscow. nine0011

You can track the position of foreign pharmaceutical companies regarding the supply of medicines to Russia in the regularly updated material of Pharmvestnik.

Tranquilizer

Grandaxin

International designation. Tofisopam

Grandaxin — State Register of Medicines, State Drug Administration

What is it. Light Hungarian tranquilizer. He has a lot of Russian-made Russian-made generics - for example, "Tofisopam", "Tofisopam-canon", "Grandapam". nine0011

Should I buy in reserve? It is enough to stock the original drug or Russian generics for 1 month.

How much do drugs cost

Drug Price
Tofisopam-canon 604 P
Grandaxin 390 P
Tofisopam 234 P

Preparation

Price

Tofisopam-canon

604 R

Grandaxin

390 R

Tofisopam

234 R

Tranquilizer

Stresam

International designation. Etifoxin

Strezam — GRLS

What is it. A slightly stronger tranquilizer than Grandaxin, which is made in France. There are no generics of this drug in the Russian Federation.

Should I buy in reserve. nine0064 This drug works well at the beginning, but gradually loses its effectiveness over 4-6 weeks. Therefore, it makes sense to stock the original drug for a maximum of one and a half months.

How much do drugs cost

Drug Price
Strezam 625 P

Preparation

Price

Strezam

625 Р

Tranquilizer

Neurontin

International designation. Gabapentin

Neurontin — GRLS

What is it. An American drug that was developed as an antiepileptic - but later it turned out that it also has an anti-anxiety effect. Neurontin has many Russian generics. For example, "Gabapentin", "Gabapentin-canon", "Konvalis".

Should I buy in reserve. Unlike other tranquilizers, this drug usually does not lose its effectiveness, so it can be taken for more than a month. Therefore, it makes sense to find out from the doctor, clarify the terms, how much you need to take the medicine, and make a supply for the entire period. You can stock up on both the original drug and its generic. nine0011

How much drugs cost

Drug Price
Neurontin 886 R
Convalis 569 R
Gabapentin 377 P

Preparation

Price

Neurrantin

886 R

Convalis

569 R

Gabapentin

9000 377 p 977 r

Tranquilizer

Lyrics

International designation. Pregabalin

Lyrica — GRLS

What is it. Another American drug, which was also originally developed as an antiepileptic. Later it turned out that it has anti-anxiety and analgesic effects - now this remedy is used to treat neuropathic pain. This drug has a lot of generics, including Russian ones. For example, Pregabalin, Pregabalin-SZ, Hungarian Pregabalin Richter. nine0011

Should I buy in reserve? Doctors prescribe this drug very rarely and only for very strict indications. It is sold by only a few pharmacies in Moscow. Most likely, this drug will not disappear, it makes little sense to stock up on it. But just in case, if there is such a need, you can purchase a supply of the original product or a Russian generic for a month.

How much do drugs cost

nine0315
Drug Price
Lyrica 570 P
Pregabalin Richter 209 P

Drug

Price

Lyrica

570 R

Pregabalin Richter 9001 9096

Benzodiazepine tranquilizer

Phenazepam

International designation. Bromdihydrochlorophenylbenzodazepine

Phenazepam — GRLS

What is it. A strong tranquilizer that effectively relieves anxiety, but can lead to addiction if used regularly and for a long time. "Phenazepam" is produced only in Russia.

Should I buy in reserve. "Phenazepam" is a strictly controlled drug, it is rarely prescribed. Now he has disappeared from pharmacies - but most likely, this is temporary. If you or your loved ones need this medicine, you need to contact your doctor and find out how it can be replaced. nine0011

How much drugs cost

Drug Price
Phenazepam from 182 R

Preparation

Price

Phenazepam

Benzodiazepine tranquilizer

Clonazepam

International designation. Clonazepam

Clonazepam - GRLS

What is it. nine0064 A strong tranquilizer produced in Poland. There is a Russian generic, which is also called "Clonazepam".

Is it worth buying in reserve . Clonazepam is a strictly controlled drug, it is rarely prescribed. Now both Polish and Russian medicines have disappeared from pharmacies - but most likely this is temporary. If you or your loved ones need this medicine, you need to contact your doctor and find out how it can be replaced.

nine0311 Price
Preparation
Clonazepam from 109 R

Preparation

Price

Clonazepam

Benzodiazepine tranquilizer

Lorafen

International designation. Lorazepam

Lorafen — GRLS

What is it. A strong tranquilizer produced in Poland. There is a Russian generic called Lorazepam. nine0011

Should I buy in reserve? "Lorafen" is a strictly controlled drug, it is rarely prescribed. Now both Polish and Russian medicines have disappeared from pharmacies - but most likely this is temporary. If you or your loved ones need this medicine, you need to contact your doctor and find out how it can be replaced.

Preparation Price
Lorafen 220 P

Preparation

Price

Lorafen

220

Benzodiazepine tranquilizer

Alprazolam

International designation. Alprazolam

Alprazolam - GRLS

What is it. Russian pharmacies receive only Russian-made drugs.

Should I buy in reserve. This drug has not been available in Russian pharmacies for a very long time. So far, other benzodiazepine tranquilizers have been prescribed instead, such as Phenazepam or Clonazepam. nine0011

SSRI antidepressants

Zoloft

International designation. Sertraline

Zoloft - GRLS

What is it. The most prescribed antidepressant produced in Italy and Germany. It does not have Russian generics, but there are two Indian ones - "Serenata" and "Serlift".

Should I buy in reserve. The manufacturing company is not going to stop the supply of Zoloft to Russia. With Indian generics, most likely, there will also be no interruptions - although they often cost more than the original drug. Probably, the drug will not disappear from pharmacies, but the price may increase. Antidepressants are usually taken for a long time, so it makes sense to stock up on medicine for 2-3 months. nine0011

How much drugs cost

Drug Price
Serenata 591 R
Zoloft 520 P
Serlift 298 R

Preparation

Price

Serenata

591

Zoloft

520 R

CERLIFT

9000 298 R

nine0008 SSRI antidepressants

Cipralex

International designation. Escitalopram

Cipralex - GRLS

What is it. Danish-made antidepressant. Escitalopram-based drugs are the second most popular antidepressant after sertraline. The expensive original Cipralex has a lot of generics: for example, the Russian Escitalopram-SZ, the Polish Elicea Ku-tab, the Hungarian Lenuksin.

Should I buy in reserve. nine0064 It is unlikely that the original drug or its generics will disappear from pharmacies, but their prices may rise significantly. If you are taking a drug with escitalopram, it makes sense to stock up on it for 2-3 months.

How much do drugs cost

Drug Price
Cipralex 2519 R
Elycea Ku-tab 685 P
Escitalopram-SZ 363 R

Preparation

Price

TsipRYLEKS

2519 R

Elicea Ku-Tab

9000

SSRI antidepressants

Fevarin

International designation. Fluvoxamine

Fevarin — GRLS

What is it. "Fevarin" is the third most used and most important antidepressant from the SSRI group, which is produced in the Netherlands. There are Russian generics: for example, pharmacies have Rokona. nine0011

Should I buy in reserve? It is unlikely that Fevarin or its generics will disappear from the market - but their prices may rise significantly. It makes sense to stock up on a medicine or its generic for 2-3 months.

How much do drugs cost

Drug Price
Rokona 1150 R
Fevarin 849 P

Preparation

SSRI antidepressants

Prozac

International designation. Fluoxetine

Prozac — GRLS

What is it. The oldest and cheapest drug from the group of selective reuptake inhibitors, which is produced by the American company Eli Lilly. This remedy has many generics: for example, the Russian Fluoxetine and Fluoxetine-Canon, and the Austrian Fluoxetine-Lannacher. nine0011

Is it worth buying in reserve . Prozac has not been sold in Russia for a long time. However, its generics are still the most inexpensive of the SSRI antidepressants. They will not disappear from the market and are unlikely to rise in price much. But if you take drugs with fluoxetine, just in case, it makes sense to stock up on them for 1-2 months.

How much do drugs cost

Drug Price
Fluoxetine-canon from 147 R
Fluoxetine Lannacher 119 R
Fluoxetine 57 R

Preparation

Price

Fluoxetine-Canon

9000

SSRI antidepressants

Paxil

International designation. Paroxetine

Paxil — GRLS

What is it. An antidepressant produced in Polish and Russian factories. This drug has a lot of generics, including Russian ones. For example, Paroxetine and Paroxetine-SZ.

Should I buy in reserve. This antidepressant has more side effects than other SSRIs. Therefore, it is not prescribed very often, and it is unlikely to be in short supply. Those people who are still suitable for drugs with paroxetine do not need to stock up on them. nine0011

How much drugs cost

Drug Price
Paxil 364 R
Paroxetine 313 R
Paroxetine-SZ 231 P

Preparation

Price

PAXIL

364 P

Paroxetine

313 p

Paroxetin-SZ

9000 231 231 R 1

Serotonin and norepinephrine reuptake inhibitor antidepressants Effexor

Effexor

International designation. Venlafaxine

What is it. The original drug has not been sold in Russia for a very long time, but there are a lot of generics. For example, the Russian Venlafaxin and Venlafaxin-ALSI, the Latvian Venlaxor.

Should I buy in reserve. Generics of this drug are unlikely to disappear from pharmacies. Prices for it are also unlikely to rise significantly. It is not necessary to stock up on this drug. nine0011

How much drugs cost

Drug Price
Venlaxor 905 P
Venlafaxine 430 P
Venlafaxine-ALSI 269 Р

drug

Price

Venalakor

011

269 R

Serotonin and norepinephrine reuptake inhibitor antidepressants

simbalta

International designation. Duloxetine

Simbalta - GRLS

What is it. An antidepressant manufactured by the American company Eli Lilly. In March 2022, this pharmaceutical company announced that it was stopping the supply of several drugs to Russia - but Simbalta was not among them. This drug has many generics - for example, the Russian "Duloxetine-Canon", the Slovenian "Duloxenta" and the Polish "Depratal". nine0011

Should I buy in reserve? So far there is Simbalta in Russia, but it is already very expensive. Generics of this drug are unlikely to disappear from pharmacies - although their prices may rise. Just in case, you can make a reserve for 2-3 months.

How much do drugs cost

Drug Price
Simbalta 3670 R
Duloxetine-canon 2199 R
Duloxenta 800 R

Preparation

Price

SIMBALTA

3670 P

Dulsetin-Canon

2199 R

DULLSENT

9000 800 800 R

Serotonin and norepinephrine reuptake inhibitor antidepressants

Ixel

International designation. Milnacipran

Ixel - GRLS

What is it. nine0064 A unique French drug that belongs to the same class of drugs as SNRI antidepressants. Used to treat certain types of depression. Also, the norepinephrine effect of milnacipran blocks pain signals in the brain, so it is used to treat fibromyalgia - severe soreness in the muscles. There are no officially registered generics in Russia.

Should I buy in reserve. If the supply of this drug to Russia stops, it will not be possible to replace it. People who take this drug need to make a supply of it. But to understand how much medicine to buy, you need to consult with your doctor. nine0011

How much drugs cost

Drug Price
Ixel 1775 P

Drug

Price

Ixel

1775 R

Antidepressants from other groups

Brintellix

International designation. Vortioxetine

Brintellix — GRLS

What is it. nine0064 This is a new antidepressant that is produced in Denmark. This drug has no analogues and generics.

Should I buy in reserve. The manufacturer, the Lundbeck company, does not plan to stop deliveries to Russia, so the drug should not disappear from pharmacies in the near future. However, this expensive drug may further increase in price due to logistics difficulties. If only this drug is suitable for you and other antidepressants are not suitable, you should discuss with your doctor whether it is worth making a supply for 2-3 months. nine0011

How much drugs cost

Drug Price
Brintellix 1890 R

Preparation

Price

Brintellix

1890 Р

Serotonin and norepinephrine reuptake inhibitor antidepressants

Mirtazapine

International designation. Mirtazapine

Mirtazapine Canon - GRLS

What is it. The drug is so old that the original has long disappeared from sale. He has many generics, including the Russian "Mirtazapin-canon" and the Croatian "Calixta".

Should I buy in reserve. This drug is unlikely to run out of stock or become very expensive. They don't need to stock up.

How much do drugs cost

Drug Price
Calixta 980 P
Mirtazapine-canon 693 P

Preparation

Price

Serotonin and norepinephrine reuptake inhibitor antidepressants

Trittico

International designation. Trazodone

Trittiko - GRLS

What is it. Italian-made antidepressant, which is more often prescribed as a sleeping pill and as a corrector for side effects associated with libido disorders. There are no generics.

Should I buy in reserve. It is unlikely that there will be a shortage of this drug - after all, it will be prescribed quite rarely. Nevertheless, if you have been prescribed it, you can buy it for 2-3 months in advance.

How much do drugs cost

Preparation Price
Trittiko 1236 R

Preparation

Price

Normotimics

Lamictal

International designation. Lamotrigine

Lamictal — GRLS

What is it. A very old drug from the British company GSK (GlaxoSmithKline), which was originally invented for the treatment of epilepsy - and then it turned out that it can also stabilize mood. He has a lot of generics: for example, the Russian Lamotrigine and Lamotrigine Canon, the Indian Lamitor. nine0011

Should I buy in reserve? This drug is unlikely to disappear, so it makes no sense to stock up on them.

How much do drugs cost

Drug Price
Lamotrigine-canon 408 P
Lamitor 404 P
Lamotrigine 293 R

Preparation

Price

Lamotrigine-canon

408 R

Lamitor

404 R

Lamotrigine

293 R

Normotimics

Depakine

International designation. Derivative of valproic acid - sodium valproate.

Depakin — GRLS

What is it. A French drug manufactured by Sanofi. Representatives of the company said that they would not limit the supply of the drug - however, due to difficulties with delivery, it may disappear from pharmacies or noticeably rise in price. However, this normotimic has many generics, for example, the Russian "Konvuleks" and the Indian "Enkorat-chrono". However, this normotimic has many generics, for example, the Russian "Konvuleks" and the Indian "Enkorat-chrono". nine0011

Should I buy in reserve? Generics of this drug are unlikely to rise in price or disappear from the Russian market, so there is no point in stocking them up.

How much do drugs cost

Drug Price
Convulex 1399 R
Depakine 283 R
Encorate Chrono 122 P

drug

Price

Convulex

1399 R

Depakin

283 283

ENCORAT-KHRONO

122 R

Normotimics

Finlepsin

International designation. Carbamazepine

Finlepsin - GRLS

What is it. Normotimik of the German pharmaceutical company Menarini-Von Heiden, which has many generics, including Russian ones. For example, Carbamazepine-avexima, Carbamazepine, Carbamazepine-ALSI, Indian Zeptol, Italian Tegretol. nine0011

Should I buy in reserve? The drug is unlikely to disappear from sale, but now it is not available in all pharmacies. Consult your doctor if it is worth buying it in reserve.

How much do drugs cost

Drug Price
Carbamazepine from 137 R

Drug

Price

Carbamazepine

from 137 Р

Normotimics

Trileptal

International designation. Oxcarbazepine

Trileptal - GRLS

What is it. Relatively new Swiss normotimic, he has few generics. Two are produced in Russia: Oxcarbazepine and Oxcarbazepine-nativ, but now they are not on sale.

Should I buy in reserve. The Swiss company Novartis, which produces Trileptal, has not yet announced the termination of drug supplies to Russia. There are a lot of stocks of this drug in pharmacies and warehouses, so it is unlikely that it will disappear from pharmacies or rise in price in the near future. There is no point in purchasing. nine0011

How much drugs cost

Drug Price
Trileptal 349 P

Drug

Price

Trileptal

349 R

Normotimics

Sedalite

International designation. Lithium carbonate

Sedalite — GRLS

What is it. Normotimik, which is produced by different countries, but in Russia there is only a Russian-made drug. Very cheap, available everywhere. It won’t disappear from pharmacies, it makes no sense to stock up. nine0011

Should I buy in reserve? Very cheap drug, available everywhere. It won’t disappear from pharmacies, it makes no sense to stock up.

How much do drugs cost

Drug Price
Sedalite 105 P

Preparation

Price

Sedalit

105 R

Antipsychotics

Seroquel

International name. Quetiapine

Seroquel - GRLS

What is it. Old British made antipsychotic. The drug has many generics, including Russian ones. For example, Quetiapin, Quetiapin Vertex, Quetiapin Canon, Croatian Servitel, Slovenian Quentiax and many other drugs.

Should I buy in reserve. It is unlikely that the drug will disappear from pharmacies or become very expensive. It makes no sense to buy it for the future. nine0011

How much drugs cost

Drug Price
Quetiapine-canon 2041 P
Quetiapine 1089 P
Quetiapine Vertex 311 R

Preparation

Price

Quebiapin-Canon

2041 R

Quetiapin

1089 1089 1089 qvetiapin-vertext

011

311 R

Antipsychotics

Aripiprazole

International designation. Aripiprazole

Aripiprazole — GRLS

What is it. The original drug has not been on sale in Russia for a long time. But this drug has generics. These are the Russian Ralotex and Zilaksera, the Croatian Ariprizol, the Hungarian Amdoal.

Should I buy in reserve. It is unlikely that the drug will disappear from pharmacies, but the price of it may increase. Consult your doctor if it is worth buying it in reserve. nine0011

How much drugs cost

Drug Price
Amdoal 7040 R
Zilaxera 4149 R
Ariprazol 3950 R

Preparation

Price

AMDOL

7040 R

4149 R

011

Antipsychotics

Rispolept

International designation. Risperidone

Rispolept — GRLS

What is it. A very old American antipsychotic. The drug has a lot of generics: Russian "Risperidon-canon", "Risperidon", "Risperidon-organic" and many other drugs.

Should I buy in reserve. It is unlikely that the drug will disappear from pharmacies. It makes no sense to buy it for the future.

How much drugs cost

Drug Price
Risperidone 308 R
Risperidone-canon 153 R
Organic risperidone 136 R

Preparation

Price

Risperidone

308 Risperidone Canon

153 R

Risperidone-organic0011

136 R

Antipsychotics

Zyprexa

International designation. Olanzapine

Zyprexa - GRLS

What is it. A Swiss antipsychotic manufactured by the American company Eli Lilly. In March 2022, this pharmaceutical company announced that it was stopping the supply of several drugs to Russia - but Zyprexa was not among them. In addition, this medicine has a lot of generics, including Russian ones: Olanzapine, Olanzapine-Canon, Olanzapine-SZ, Hungarian Egolanza, Polish Zolafren Quick. nine0011

Should I buy in reserve? Although there will be no originator drug on the market, generics will remain. There is no point in stocking up on Zyprexa.

How much do drugs cost

Drug Price
Olanzapine 569 R
Olanzapine-canon 265 P
Olanzapine-SZ 209 P

Preparation

Price

Olanzapin

569 R

Olanzapin-Canon

265 265 265 Olanzapin-SZ

209 R

Sleeping pills

Andante

International designation. Zaleplon

Andante — GRLS

What is it. Hungarian hypnotic drug, which has only one Polish generic - "Sonata-adamed".

Should I buy in reserve. nine0064 Although this drug is not produced in the Russian Federation, Polish pharmaceutical companies have not yet announced their withdrawal from the Russian market. Now you can only find "Sonata-Adamed" for sale. However, if you already have a package of this drug, you should not buy it for future use.

How much do drugs cost

Drug Price
Adamed Sonata 511 R

Preparation

Price

Sonata-adamed

511 R

Why it does not make sense to make reserves "Sonata-Andamed"

Sergey Divisenko

Psychotherapist

Preparations with a gulpers belong to the Z-adults class. By action, these drugs resemble tranquilizers - this means that they cannot be taken for a long time. If you have already purchased one package, you should not stock up on medicine for the future. The package is enough to complete the course.

If you did not have time to buy a medicine before it disappeared from pharmacies or the price went up, consult your doctor - he will tell you which drug can replace it. This can be either an antidepressant with a hypnotic effect, such as mirtazapine or trazodone, or a 2nd generation antipsychotic, such as quetiapine. nine0011

Sleeping pills

Melatonin

International designation. Melatonin

Melatonin — GRLS

What is it. Melatonin preparations and supplements help you fall asleep faster and sleep better.

They are produced in all countries. For example, Melatonin, Melatonin-SZ, Melarithm are made in Russia.

Should I buy in reserve. Medicines and supplements with melatonin will not disappear from pharmacies and are unlikely to rise in price, there is no point in buying them. nine0011

How much drugs cost

Drug Price
Melatonin-SZ 400 P
Melatonin 404 P
Melarithm 318 P

Preparation

Price

Melatonin-SZ

400 R

Melatonin

404 R

Melaritm

9000 318 R 918 R

Sleeping pills

Donormil

International designation. Doxylamine

Donormil — GRLS

What is it. French sleeping pill, which is allowed for pregnant women. The drug has many generics, including Russian ones: Doxylamine Organic, Doxylamine-SZ, Slovenian Slipzon.

Should I buy in reserve. The drug will not disappear from pharmacies and is unlikely to rise in price, there is no point in buying it.

How much do drugs cost

Preparation Price
Slipzon 305 P
Doxylamine-SZ 149 P
Organic doxylamine 96 P

Preparation

Price

Slipzon

305 R

DOXILAMIN-SZ

149 R

DOXILAMIN-ORGANIC

9000 96

nine0008 Sleeping pills

Valdoxan

International designation. Agomelatine

Valdoxan — GRLS

What is it. A French drug that has a hypnotic effect. Some doctors use it to treat insomnia that other drugs don't work for. Generics are produced in Russia - for example, Agomelatine and Agteminol, but so far they are not on sale.

Should I buy in reserve. Most likely, Valdoxan will not disappear from the market and is unlikely to become much more expensive, so it makes no sense to stock up on them. nine0011

How much drugs cost

Drug Price
Valdoxan 1499 P

Preparation

Price

Valdoxan

1499 Р

ADHD drug for children and adults

Strattera

International designation. Atomoxetine

Strattera — GRLS

What is it. American drug manufactured by Eli Lilly.

Learn more