Symptoms of celexa

Citalopram (Celexa) | NAMI: National Alliance on Mental Illness

Brand names:

Celexa®
- Tablets: 10 mg, 20 mg, 40 mg
Citalopram
- Tablets: 10 mg, 20 mg, 40 mg
- Liquid: 10 mg/5 ml

Generic name: citalopram (sye TAL oh pram)

All FDA black box warnings are at the end of this fact sheet. Please review before taking this medication.

What Is Citalopram And What Does It Treat?

Citalopram is an antidepressant medication that works in the brain. It is approved for the treatment of major depressive disorder (MDD).

Symptoms of depression include:

Depressed mood - feeling sad, empty, or tearful
Feeling worthless, guilty, hopeless, and helpless

Loss of interest or pleasure in your usual activities
Sleep and eat more or less than usual (for most people it is less)
Low energy, trouble concentrating, or thoughts of death (suicidal thinking)
Psychomotor agitation (‘nervous energy’)
Psychomotor retardation (feeling like you are moving and thinking in slow motion)
Suicidal thoughts or behaviors

Citalopram may also be helpful when prescribed “off-label” for obsessive-compulsive disorder, generalized anxiety disorder, panic disorder, social phobia (also known as social anxiety disorder), posttraumatic stress disorder, eating disorders such as binge eating disorder, and premenstrual dysphoric disorder (PMDD). “Off-label” means that it hasn’t been approved by the Food and Drug Administration for this condition. Your mental health provider should justify his or her thinking in recommending an “off-label” treatment. They should be clear about the limits of the research around that medication and if there are any other options.

What Is The Most Important Information I Should Know About Citalopram?

Do not stop taking citalopram even when you feel better. With input from you, your health care provider will assess how long you will need to take the medicine.

Missing doses of citalopram may increase your risk for relapse in your symptoms.

Stopping citalopram abruptly may result in one or more of the following withdrawal symptoms: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin).

Depression is also a part of bipolar illness. People with bipolar disorder who take antidepressants may be at risk for "switching" from depression into mania. Symptoms of mania include "high" or irritable mood, very high self-esteem, decreased need for sleep, pressure to keep talking, racing thoughts, being easily distracted, frequently involved in activities with a large risk for bad consequences (for example, excessive buying sprees).

Medical attention should be sought if serotonin syndrome is suspected. Please refer to serious side effects for signs/symptoms.

Are There Specific Concerns About Citalopram And Pregnancy?

If you are planning on becoming pregnant, notify your health care provider to best manage your medications. People living with MDD who wish to become pregnant face important decisions. Untreated MDD has risks to the fetus, as well as the mother. It is important to discuss the risks and benefits of treatment with your doctor and caregivers. For women who take antidepressant medications during weeks 13 through the end of their pregnancy (second and third trimesters), there is a risk that the baby can be born before it is fully developed (before 37 weeks).

For mothers who have taken SSRIs during their pregnancy, there appears to be less than a 1% chance of infants developing persistent pulmonary hypertension. This is a potentially fatal condition that is associated with use of the antidepressant in the second half of pregnancy. However, women who discontinued antidepressant therapy were five times more likely to have a depression relapse than those who continued their antidepressant. If you are pregnant, please discuss the risks and benefits of antidepressant use with your health care provider.

Caution is advised with breastfeeding since citalopram does pass into breast milk.

What Should I Discuss With My Health Care Provider Before Taking Citalopram?

Symptoms of your condition that bother you the most
If you have thoughts of suicide or harming yourself
Medications you have taken in the past for your condition, whether they were effective or caused any adverse effects
If you experience side effects from your medications, discuss them with your provider. Some side effects may pass with time, but others may require changes in the medication.
Any other psychiatric or medical problems you have, including a history of bipolar disorder
All other medications you are currently taking (including over the counter products, herbal and nutritional supplements) and any medication allergies you have
Other non-medication treatment you are receiving, such as talk therapy or substance abuse treatment. Your provider can explain how these different treatments work with the medication.
If you are pregnant, plan to become pregnant, or are breastfeeding
If you drink alcohol or use drugs

How Should I Take Citalopram?

Citalopram is usually taken one time per day with or without food.

Typically patients begin at a low dose of medicine and the dose is increased slowly over several weeks.

The dose usually ranges from 20 mg to 40 mg once daily. For patients older than 60 years, the maximum recommended dose is 20 mg once daily. Only your health care provider can determine the correct dose for you.

The liquid should be measured with a dosing spoon or oral syringe which you can get from your pharmacy.

If you are taking citalopram, you should not take other medications that include escitalopram (Lexapro®).

Consider using a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member or friend to remind you or check in with you to be sure you are taking your medication.

What Happens If I Miss A Dose Of Citalopram?

If you miss a dose of citalopram, take it as soon as you remember, unless it is closer to the time of your next dose. Discuss this with your health care provider. Do not double your next dose or take more than what is prescribed.

What Should I Avoid While Taking Citalopram?

Avoid drinking alcohol or using illegal drugs while you are taking antidepressant medications. They may decrease the benefits (e. g., worsen your condition) and increase adverse effects (e.g., sedation) of the medication.

What Happens If I Overdose With Citalopram?

If an overdose occurs, call your doctor or 911. You may need urgent medical care. You may also contact the poison control center at 1-800-222-1222.

A specific treatment to reverse the effects of citalopram does not exist.

What Are The Possible Side Effects Of Citalopram?

Common side effects

Headache, nausea, diarrhea, dry mouth, increased sweating, feeling nervous, restless, fatigue, or having trouble sleeping (insomnia). These will often improve over the first week or two as you continue to take the medication.

Sexual side effects, such as problems with orgasm or ejaculatory delay often do not diminish over time.

Rare/serious side effects

Low sodium blood levels (symptoms of low sodium levels may include headache, weakness, difficulty concentrating and remembering), teeth grinding, angle closure glaucoma (symptoms of angle closure glaucoma may include eye pain, changes in vision, swelling or redness in or around eye), serotonin syndrome (symptoms may include shivering, diarrhea, confusion, severe muscle tightness, fever, seizures, and death), seizure

SSRI antidepressants including citalopram may increase the risk of bleeding events. Combined use of aspirin, nonsteroidal anti-inflammatory drugs (e.g., ibuprofen, naproxen), warfarin, and other anti-coagulants may increase this risk. This may include symptoms such as gums that bleed more easily, nose bleed, or gastrointestinal bleeding. Some cases have been life threatening.

Risk of abnormal heart rhythms with citalopram

August 2011: Citalopram at doses greater than 40 mg per day could potentially cause a dangerous abnormality in the electrical activity of the heart. Citalopram use is discouraged in patients with congenital long QT syndrome. Patients with low levels of potassium and magnesium in the blood are also at increased risk. If you are currently taking citalopram at a dose greater than 40 mg per days, talk to your health care professional. Seek immediate care if you experience an irregular heartbeat, shortness of breath, dizziness, or fainting while taking citalopram. If you are taking citalopram, your health care professional may occasionally order an electrocardiogram (ECG, EKG) to monitor your heart rate and rhythm. Your health care provider may also order tests to check levels of potassium and magnesium in your blood.

Are There Any Risks For Taking Citalopram For Long Periods Of Time?

To date, there are no known problems associated with long term use of citalopram. It is a safe and effective medication when used as directed.

What Other Medications May Interact With Citalopram?

Citalopram should not be taken with or within 2 weeks of taking monoamine oxidase inhibitors (MAOIs). These include phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®), rasagiline (Azilect®), and selegiline (Emsam®).

Although rare, there is an increased risk of serotonin syndrome when citalopram is used with other medications that increase serotonin, such as other antidepressants, migraine medications called “triptans” (e.g., Imitrex®), some pain medications (e.g., tramadol (Ultram®), the antibiotic linezolid (Zyvox®), and amphetamines.

Citalopram may increase the effects of other medications that can cause bleeding (e. g., ibuprofen (Advil®, Motrin®), warfarin (Coumadin®) and aspirin).

Increased risk of QT prolongation when used with:

Certain antiarrhythmics: quinidine (Quinidex Extentabs®, Quinaglute®, Quinalan®), procainamide (Procanbid®, Pronestyl®, Pronestyl-SR®), amiodarone (Cordarone®, Pacerone®), sotalol (Betapace®, Sorine®)
Certain antipsychotics: chlorpromazine (Thorazine®), thioridazine (Mellaril®)
Certain antibiotics: gatifloxacin (Tequin®), moxifloxacin (Avelox®)
Methadone®

How Long Does It Take For Citalopram To Work?

Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.

Summary of FDA Black Box Warnings

Suicidal thoughts or actions in children and adults

Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients with major depressive disorder (MDD), both adult and pediatric, may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in behavior, whether or not they are taking antidepressant medications. This risk may persist until significant remission occurs.

In short-term studies, antidepressants increased the risk of suicidality in children, adolescents, and young adults when compared to placebo. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24. Adults age 65 and older taking antidepressants have a decreased risk of suicidality. Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or health care professional. All patients being treated with antidepressants for any indication should watch for and notify their health care provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.

Provided by

(December 2020)

©2020 The College of Psychiatric and Neurologic Pharmacists (CPNP) and the National Alliance on Mental Illness (NAMI). CPNP and NAMI make this document available under the Creative Commons Attribution-No Derivatives 4.0 International License. Last Updated: January 2016.

This information is being provided as a community outreach effort of the College of Psychiatric and Neurologic Pharmacists. This information is for educational and informational purposes only and is not medical advice. This information contains a summary of important points and is not an exhaustive review of information about the medication. Always seek the advice of a physician or other qualified medical professional with any questions you may have regarding medications or medical conditions. Never delay seeking professional medical advice or disregard medical professional advice as a result of any information provided herein. The College of Psychiatric and Neurologic Pharmacists disclaims any and all liability alleged as a result of the information provided herein.

Celexa Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Warnings:

Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits. However, studies have shown that a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. It is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition.

Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.

Warnings:

Uses

Citalopram is used to treat depression. It may improve your energy level and feelings of well-being. Citalopram is known as a selective serotonin reuptake inhibitor (SSRI). This medication works by helping to restore the balance of a certain natural substance (serotonin) in the brain.

How to use Celexa

Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking citalopram and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication with or without food as directed by your doctor, usually once daily in the morning or evening. The dosage is based on your medical condition, response to treatment, age, laboratory tests, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

To reduce your risk of side effects, your doctor may direct you to start taking this drug at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Keep taking this medication even if you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Also, you may experience symptoms such as mood swings, headache, tiredness, sleep changes, and brief feelings similar to electric shock. To prevent these symptoms while you are stopping treatment with this drug, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details. Report any new or worsening symptoms right away.

It may take 1 to 4 weeks to feel a benefit from this drug and up to several weeks before you get the full benefit.

Tell your doctor if your condition does not improve or if it worsens.

Side Effects

See also Warning and Precautions sections.

Nausea, dry mouth, loss of appetite, tiredness, drowsiness, sweating, blurred vision, and yawning may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: shaking (tremor), decreased interest in sex, changes in sexual ability, easy bruising/bleeding.

Get medical help right away if you have any very serious side effects, including: fainting, fast/irregular heartbeat, black stools, vomit that looks like coffee grounds, seizures, eye pain/swelling/redness, widened pupils, vision changes (such as seeing rainbows around lights at night).

This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help right away, or permanent problems could occur.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking citalopram, tell your doctor or pharmacist if you are allergic to it; or to escitalopram; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: personal or family history of bipolar/manic-depressive disorder, personal or family history of suicide attempts, liver disease, seizures, low sodium in the blood, intestinal ulcers/bleeding (peptic ulcer disease) or bleeding problems, personal or family history of glaucoma (angle-closure type).

Citalopram may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using citalopram, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, recent heart attack, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using citalopram safely.

This drug may make you drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially bleeding, loss of coordination, and QT prolongation (see above). They may also be more likely to develop a type of salt imbalance (hyponatremia), especially if they are also taking "water pills" (diuretics). Loss of coordination can increase the risk of falling.

Children may be more sensitive to the side effects of this drug, especially loss of appetite and weight loss. Monitor weight and height in children who are taking this drug.

During pregnancy, this medication should be used only when clearly needed. It may harm an unborn baby. Also, babies born to mothers who have used this drug during the last 3 months of pregnancy may rarely develop withdrawal symptoms such as feeding/breathing difficulties, seizures, muscle stiffness, or constant crying. If you notice any of these symptoms in your newborn, tell the doctor promptly.

Since untreated mental/mood problems (such as depression, obsessive-compulsive disorder, panic disorder) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Interactions

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Do not share this medication with others.

Laboratory and/or medical tests (such as EKG) should be done periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Keep all regular medical and psychiatric appointments.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Plexitis: symptoms and treatment | Diagnostics of plexopathy in JSC "Medicina"

Article content

General information
Causes of disease development
Symptoms of plexitis
Types of disease
Pathology diagnostics
Treatment of plexitis
Surgical treatment
Rehabilitation after surgical treatment
Forecast
Disease prevention
Questions and answers
Sources and literature

Plexitis (plexopathy) is a pathology that develops against the background of damage to the nerve plexuses formed by the spinal nerves. Symptoms of the disease are specific: decreased muscle tone, absence of tendon reflexes, muscle atrophy. The running course of plexitis can be complicated by partial or complete paralysis of the upper and lower extremities. Treatment of the disorder is carried out under the supervision of a neurologist.

General

The nerves emerging from the spinal column are divided into two branches - the posterior and anterior. The anterior one forms paired nerve plexuses localized in the neck, shoulders and lower back. Damage to these anatomical structures leads to the development of plexitis. Pathology is diagnosed in people of all age groups, most often in men over 35 years old. If left untreated, the acute form of plexopathy can become chronic and cause atrophy of the muscles of the upper or lower extremities.

The symptomatology of plexopathies is manifested due to the partial or complete rupture of the fibers that form the nerve plexuses. Hematomas or edema, which have developed due to damage to soft tissues, contribute to compression of the nerves and disruption of their conduction.

Causes of the development of the disease

Plexitis manifests itself against the background of traumatic lesions of the soft tissues of the neck, shoulder or lumbar region:

bruises;
gunshot, stab or cut wounds;
dislocations of the shoulder or hip joint;
excessive stretching of the muscles of the arms and legs due to excessive physical exertion.

The post-traumatic form of the disease is detected in women who have undergone complicated childbirth. Non-traumatic causes of plexitis include:

malignant and benign tumors in the area of the nerve plexuses;
congenital and acquired anomalies of the spine;
certain types of viral and bacterial infections;
autoimmune pathologies;
endocrine disorders.

Often plexopathies become a complication of inflammatory processes - cystitis, salpingitis, prostatitis, adnexitis, etc.

Symptoms of plexitis

Pathological manifestations are specific. In 85% of cases, patients suffer from unilateral plexopathy. Its main features are:

weak muscle tone;
decreased sensitivity;
local edema and hyperemia;
acute pain in the area of the nerve plexus;
a pronounced decrease in the physical strength of the upper or lower extremities.

These symptoms are typical for the neuralgic stage of the disease. The paralytic form of plexitis is characterized by the development of muscle paralysis, atrophy of muscle tissues, and the absence of tendon reflexes. In the affected area, foci of trophic disorders are formed: swelling of the skin and excessive sweating.

Against the background of adequate treatment, the pathology enters the recovery stage, lasting up to 12 months. The level of restoration of motor functions depends on the initial volume of damage to nerve fibers.

Types of disease

Neurologists distinguish three types of plexopathies based on the localization of the pathological focus:

cervical;
shoulder;
lumbar.

Damage to the nerve plexuses in the cervical spine is characterized by acute pain in the anterior and lateral surfaces of the neck. Often the pain syndrome spreads to the ear and back of the head. When the phrenic nerve is irritated, the patient experiences persistent bouts of hiccups. The paralytic stage of the disease is characterized by atrophy of the cervical muscles and weakening of the diaphragm.

The brachial type of plexopathies can occur in three forms: upper, lower and total. In the latter case, the pain syndrome spreads to all tissues of the upper limb. At the paralytic stage of the disease, atrophy of the muscles of the arm and shoulder girdle develops, often complicated by shoulder dislocations.

Lumbar plexitis causes pain on the front of the thigh. Adults and children suffer from the inability to flex the hip and knee joints. Over time, atrophic changes develop in the gluteal and femoral muscles. Often, the pathology is complicated by contracture of the knee joint.

Pathology diagnostics

The neurologist collects objective data for anamnesis and conducts an examination:

reveals the focus of damage to the nerve plexuses;
evaluates the muscle tone of the limbs;
studies the degree of decrease in tendon reflexes;
tests the sensitivity of the skin and muscle tissues.

Confirmation of the primary diagnosis is performed using electroneurography and electromyography, radiography, computed tomography and ultrasound examination of the affected area. If there are relevant indications, the patient receives a referral for consultation with a traumatologist, orthopedist, urologist, gynecologist or oncologist.

Plesopathies are differentiated from radiculitis, poliomyelitis, neuritis, joint damage, osteochondrosis, arthritis and other diseases with similar symptoms.

Treatment of plexitis

A therapeutic course against the background of a post-traumatic type of disease is developed by a neurologist and a traumatologist. Shown:

limb immobilization;
anti-inflammatory drugs;
painkillers;
moderate physical activity.

Plexitis of infectious origin requires the use of antibiotics. With endocrine disorders, hormonal drugs are prescribed. Relief of neurological symptoms is carried out with the help of neuromuscular stimulators. Improving blood circulation in the area of primary damage to nerve fibers is facilitated by injections of nicotinic acid and pentoxifylline.

The transition of the pathology to the recovery stage allows doctors to refer patients to physiotherapy procedures:

UHF therapy;
electrophoresis;
phonophoresis;
iontophoresis;
massage and exercise therapy.

In some cases, children and adults are prescribed hydrotherapy - hydrogen sulfide and radon baths.⁠

Surgical treatment

Surgical intervention is performed in post-traumatic forms of the disease that are not amenable to conservative treatment, and compression of the nerve plexus by hematomas or tumors. In the first case, surgeons perform a plastic surgery of the nerve trunk - they connect torn or completely torn nerve fibers. In the second, formations that compress the plexus of nerves are removed.

Rehabilitation after surgical treatment

The nature of rehabilitation measures depends on the type of damage that provoked the development of plexitis. In the case of gunshot, stab or cut wounds, complete rest, temporary immobilization of the limb and systematic consultations with the surgeon until the injury is completely healed are indicated. When removing malignant neoplasms, people suffering from plexitis require further treatment under the supervision of an oncologist (chemotherapy, radiation procedures, etc. ).

Forecast

Timely initiation of treatment allows doctors to form a favorable prognosis for patients of all age groups. Complete recovery can be achieved in 85–87% of cases. Refusal of treatment or lack of qualified medical care can become the causes of a person's disability.

Disease prevention

It is possible to prevent the development of traumatic forms of the disease if safety precautions are observed during physical activity: physical labor, sports training, cycling, etc. Prevention of plexopathies of infectious origin is based on the timely treatment of viral and bacterial diseases.

Questions and answers

— Which doctor deals with the treatment of plexitis?

- Diagnosis and development of treatment tactics is carried out by a neurologist. Consultations of surgeons, traumatologists, rheumatologists, infectious disease specialists, oncologists and doctors of other specializations may be required.

— Why are post-traumatic plexopathies dangerous?

- Traumatic lesions of the nerve plexuses can cause disability due to developed complications: paralysis of the upper or lower extremities.

— How effective is the conservative treatment of plexitis?

- The effectiveness of treatment depends on the genesis of the disease, the age of the patient, the presence or absence of complications. Timely initiation of drug therapy allows for complete recovery of tendon reflexes in 85% of cases.⁠

Sources and literature

The following materials were used in preparing the article:

Brief Medical Encyclopedia / Ch. editor B. V. Petrovsky. — M.: Soviet Encyclopedia, 1989.
Puzin MN Nervous diseases. - Moscow: Medicine, 2002.
Shtok V.N., Levin O.S. Reference book on the formulation of the clinical diagnosis of diseases of the nervous system. - Moscow: LLC Medical Information Agency, 2006.

Celexa side effects: what you need to know

Introduction

If you are looking for treatment options for depression, your doctor may suggest Celexa (citalopram) for your condition. This is a prescription medication used to treat depression in adults.

Celexa comes as a tablet that you take by mouth. Usually used as a long term treatment. For more information about Celex, see this detailed drug article.

Like all medicines, Celexa can cause mild or serious side effects. Keep reading to find out more.

What are the most common side effects of Celexa?

Some people may experience mild or severe side effects while taking Celexa. Examples of commonly reported side effects of Celexa may include:

nausea
drowsiness
dry mouth
insomnia (trouble sleeping)*
sweating more than usual

.90 side effects of Celexa.

What are the mild side effects of Celexa?

Celexa may cause mild side effects in some people.

Examples of mild side effects reported with Celexa include:

sexual problems in women and men*†
weight gain or weight loss*
insomnia (sleep problems)*
digestive problems such as:
- diarrhea
- indigestion
- Loss of appetite
- Nausea and vomiting
Drumeness
Dry mouth
Fatigue (low energy)
Painful menstruation
Sweep more than usually
swollen sins or nasal cavities
(trembling)
upper respiratory infections such as the common cold

In most cases, these side effects should be temporary. Some of them are easy to manage too. But if you have any symptoms that continue or bother you, talk to your doctor or pharmacist. And don't stop taking Celexa unless your doctor tells you to.

Celexa may cause mild side effects other than those listed above. See the Celexa Medication Guide for details.

After the Food and Drug Administration (FDA) approves a drug, it monitors and analyzes the drug's side effects. If you would like to notify the FDA of a side effect you had with Celexa, visit MedWatch.

What are the serious side effects of Celexa?

In rare cases, Celexa may cause serious side effects. Serious side effects reported with Celexa include:

Suicidal thoughts and behavior in children and young adults*
Withdrawal symptoms when the drug is stopped abruptly†
Bruising or bleeding more easily than usual
Abnormal heart rhythms
hypomania or mania (episodes of high energy and excitement)
low blood sodium
seizures
serotonin syndrome (high levels of a brain chemical called serotonin)
allergic reaction‡

If you develop serious side effects while taking Celexa, call your doctor right away. If the side effects seem life-threatening or if you think you need a medical emergency, call 911 or your local emergency number right away.

Side effects in children

Celexa is not approved for use in children. But in some cases, the drug can be used off-label to treat depression in children. Off-label use of a drug means the use of a drug for purposes other than those for which it has been approved by the Food and Drug Administration (FDA).

If you have questions about whether your child can take Celexa, talk to their doctor.

It is important to note that Celexa has a boxed warning for the risk of suicidal thoughts and behavior in children and young adults (ages 18 to 24). The boxed warning is the most severe warning from the FDA. It warns doctors and patients about drug side effects that can be dangerous.

See the "Explanation of Side Effects" section below for details.

Frequently Asked Questions About Celexa Side Effects

Below are answers to some frequently asked questions about Celexa side effects.

Do I have a higher risk of side effects during the first week of taking Celexa?

Yes, you may have a higher risk of certain side effects during the first week of taking Celexa.

For example, the risk of suicidal thoughts and behavior* is highest when taking Celexa immediately after you start taking the drug.

To reduce the risk of side effects from Celexa, your doctor will start with a low dose of Celexa. They may slowly increase your dosage over time until the symptoms of your condition begin to ease. For detailed dosage information, see this detailed drug article.

Will I experience withdrawal side effects if I stop taking Celexa?

Yes, you may experience withdrawal side effects if you suddenly stop taking Celexa.

Withdrawal side effects are symptoms that can occur when you stop taking a drug that your body has become addicted to. Examples of withdrawal side effects that may occur with Celexa include:

agitation
weakness
dizziness
drowsiness
dry mouth
insomnia (trouble sleeping)
nausea and vomiting

You should not stop taking Celexa unless your doctor tells you it is safe to do so. When it's time to stop taking Celexa, your doctor will gradually decrease your dosage. This helps reduce the risk of side effects of withdrawal after stopping treatment with Celexa.

Does Celexa cause any long term side effects?

Possibly. Most Celexa side effects improve or disappear within hours or days of taking the drug. But in rare cases, the side effects of Celexa can last longer.

For example, there have been reports of sexual problems* caused by antidepressants (such as Celexa) persisting for several weeks or months after stopping treatment. These long-term sexual problems were reported after antidepressants were released to the market.

Ever since Celexa was approved, abnormal heart rhythm (a rare side effect) has been reported in extremely rare cases to cause long-term, life-threatening heart problems.

If you have questions about what to expect from Celexa treatment, talk to your doctor or pharmacist.

Do the side effects of Celexa change depending on the dose I take (10mg, 20mg or 40mg)?

Yes, the side effects of Celexa may vary depending on the strength of the drug you are taking.

For example, your risk of abnormal heart rhythms from Celexa is higher if you take higher doses of the drug.

Talk to your doctor or pharmacist if you have any questions about the risk of certain side effects from Celexa or what concentration is right for your condition.

How long do the side effects of Celexa usually last?

Most side effects of Celexa last from a few hours to a few days after the start of treatment. But the duration of side effects from the drug can be different for each person taking Celexa.

For more information about what to expect from Celexa treatment, talk to your doctor or pharmacist.

Side effects explained

Find out more about some of the side effects Celexa may cause.

Sexual problems in women and men

Sexual problems are a common side effect of Celexa. These side effects can occur in both women* and men* taking the drug.

Sexual problems in men taking Celexa may include:

delayed ejaculation (when ejaculation requires more than 30 minutes of sexual stimulation)
erectile dysfunction (inability to get or maintain an erection sufficient for intercourse)
low libido (sex drive)

Sexual problems in women taking Celexa may include:

orgasm problems
low libido

Be aware that the depression that Celexa is used to treat can also cause sexual problems. Therefore, it can be difficult to tell if these side effects are caused by Celexa or the disease you are taking the drug to treat.

What can help

If you have sexual problems while taking Celexa, talk to your doctor. They can help determine if these side effects are related to your condition or to a drug.

Weight gain or weight loss

Weight gain and weight loss are common side effects of Celexa. But some weight changes may not be caused by Celexa itself. The depression that Celexa is used to treat can also cause weight changes. Therefore, a change in weight after you start taking Celexa may be a sign that the drug is working to treat your condition.

What can help

If you are concerned about weight gain or loss while taking Celexa, talk to your doctor. They may suggest ways to manage your weight during treatment.

Insomnia (trouble sleeping)

Insomnia is a common side effect of Celexa. The drug may also cause other sleep problems in some people. For example, instead of insomnia, you may feel sleepy after taking Celexa.

You will usually learn more about how Celexa affects you after you have taken several doses of the drug.

What can help

Talk to your doctor if you have insomnia or other sleep problems because of Celexa. They may recommend ways to manage this side effect.

Suicidal thoughts and behavior in children and young people

Selexa has a boxed warning for suicidal thoughts and behavior. The boxed warning is the most serious warning from the Food and Drug Administration (FDA).

This risk affects children and young adults (aged 18 to 24) who take antidepressants such as Celexa. It is important to note that Celexa is not approved for use in people under 18 years of age.

Regardless of age, this risk is highest during the first few months of treatment and after any dosage changes.

While you are taking Celexa, you should watch for the following symptoms:

restlessness
hypomania or mania (episodes of high energy and excitement)
impulsive behavior
insomnia (sleep problems)
mood changes such as agitation, aggressiveness, hostility and irritability
panic attacks
feelings of anxiety

It is important to note that suicidal thoughts and behaviors can also be depression for which Celexa is used.

What can help

Tell your doctor right away if you have any unusual changes in mood, behaviour, thoughts or feelings while taking Celexa. They may ask you to stop taking Celexa and switch to another drug to treat your condition.

If you have thoughts of harming yourself, call 911 or your local emergency number immediately.

Suicide Prevention

If you think someone is at immediate risk of harming themselves or others:

Call 911 or your local emergency number.

Stay with the person until help arrives.

Remove all weapons, knives, medicines, and other items that could cause harm.

Listen, but don't judge, argue, threaten or yell.

If you or someone you know is thinking about suicide, get help from a crisis or suicide prevention hotline. Call the National Suicide Prevention Hotline at 800-273-8255.

Allergic reaction

Like most medicines, Celexa may cause an allergic reaction in some people. This side effect was not reported in studies of the drug. But ever since Celexa became available for use, allergic reactions have been reported.

Symptoms may be mild or severe and may include:

skin rash
itching
erythema (temporary warmth, redness or discoloration of the skin)
swelling under the skin, usually on the eyelids, lips, arms or legs
swelling of the mouth, tongue, or throat that makes breathing difficult

What can help

If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. They may suggest an over-the-counter oral antihistamine such as Benadryl (diphenhydramine) or a topical product such as hydrocortisone cream to relieve your symptoms.

If your doctor confirms that you had a mild allergic reaction to Celexa, he or she will decide whether you should continue taking Celexa.

If you have symptoms of a severe allergic reaction, such as swelling or difficulty breathing, call 911 or your local emergency number right away. These symptoms can be life threatening and require immediate medical attention.

If your doctor confirms that you have had a serious allergic reaction to Celexa, he may ask you to switch to another treatment.

Tracking side effects

Consider keeping a record of any side effects you experience during your treatment with Celexa. You can then share this information with your doctor. This is especially helpful when you first start taking new medications or using a combination of treatments.

Your side effect notes may include things like:

what dose of the drug you were taking when you had the side effect

How soon after starting this dose did you experience a side effect

What were your symptoms due to the side effect

How did it affect your daily activities

What other medications did you also take

Any other information you think important

Taking notes and sharing them with your doctor will help him learn more about how Celexa affects you. Your doctor may use this information to adjust your treatment plan if necessary.

Celexa Warnings

It may not be safe to take Celexa in certain situations. Read on to learn more about possible warnings for Celexa.

Boxed Warning: Suicidal Thoughts and Behaviors in Children and Young Adults

Selexa has a boxed warning for suicidal thoughts and behaviors. The boxed warning is the most serious warning from the Food and Drug Administration (FDA).

This risk affects children and young adults (aged 18 to 24) who take antidepressants such as Celexa. It is important to note that Celexa is not approved for use in people under 18 years of age.

See the "Explanation of Side Effects" section above for more information.

Other warnings

Celexa may not be right for you if you have certain medical conditions or other health conditions. Talk to your doctor about your medical history before taking Celexa. The list below includes factors to consider.

Angle-closure glaucoma. Before starting treatment with Celexa, tell your doctor if you have angle-closure glaucoma. The drug may increase the risk of an attack of glaucoma (a sudden worsening of glaucoma that leads to blurred vision and pain in the eyes). If you develop these symptoms while taking Celexa, call 911 or your local emergency number immediately.

Bipolar disorder. Celexa may cause hypomania or mania (episodes of high energy and arousal that may be associated with bipolar disorder). Tell your doctor if you have bipolar disorder before taking Celexa. They may prescribe a drug other than Celexa for your condition.

Bleeding problems. Celexa may increase the risk of bleeding. If you already have bleeding problems, your risk of this side effect may be even higher. Tell your doctor if you have any bleeding problems before taking Celexa.

Heart problems. Celexa may cause abnormal heart rhythms. You may be at a higher risk of this side effect if you already have heart problems. Tell your doctor if you have any heart problems, such as heart failure or a recent heart attack, before taking Celexa.

Liver or kidney problems. If you have liver or kidney problems, your body may have trouble getting Celexa out of your system. This may increase the risk of side effects from the drug. Tell your doctor about any liver or kidney problems you have before taking Celexa.

Low blood sodium. Celexa may cause low blood sodium levels. If you already have low sodium, talk to your doctor before taking Celexa.

Seizures. Celexa may cause convulsions. If you already had seizures before taking the drug, your risk of this side effect may be even higher while taking Celexa. Tell your doctor if you have seizures before taking Celexa.

Allergic reaction. If you have had an allergic reaction to Celexa or any of its ingredients, your doctor will likely not prescribe Celexa. Ask your doctor which other medicines are best for your condition.

Use of monoamine oxidase inhibitors (MAOIs). MAOIs are a group of drugs used to treat depression. Before you start Celexa, tell your doctor if you are taking an MAOI. Taking these drugs together may increase the risk of serotonin syndrome. Because of this, you should not take Celexa if you are taking an MAOI. Your doctor will ask you to wait 2 weeks or more after you stop taking an MAOI before you start taking Celexa. And if you stop taking Celexa, your doctor will suggest that you wait at least 2 weeks before starting an MAOI.

Drinking alcohol and Celexa

It is recommended that you avoid drinking alcohol while taking Celexa. Drinking alcohol while taking Celexa may cause problems with clear thinking or muscle coordination.

If you drink alcohol, talk to your doctor before taking Celexa.

Pregnancy and lactation while taking Celexa

Taking Celexa while pregnant or breastfeeding may not be safe.

If you are pregnant or breastfeeding, planning to become pregnant or breastfeeding, talk to your doctor about the risks and benefits of taking Celexa.

What to ask your doctor

Celexa is used to treat depression in adults. Some people who take Celexa may experience mild side effects. In rare cases, serious side effects may also occur.

If you have any questions about the side effects of Celexa, talk to your doctor or pharmacist. Here are some questions you can ask:

What are the side effects of Selexa compared to the side effects of similar drugs such as Lexapro (escitalopram)?
How can I deal with the side effects that I may have with Celexa?
Do I have other health conditions that could increase my risk of side effects while taking Celexa?
Are there any side effects of Celexa that I should tell you about right away?

To read first-hand stories of people coping with their condition, subscribe to Drink-Drink's depression newsletter.

Ask a pharmacist

Q:

Are there any medicines that can increase my risk of side effects if I take them with Celexa?

Anonymous

A:

Yes, taking certain medications with Celexa can increase the risk of side effects. Examples of such drugs include:

Certain CYP2C19 inhibitors. Taking Celexa with these drugs may increase the risk of side effects of Celexa, including irregular heartbeats (a rare side effect). Examples of CYP2C19 inhibitorsinclude omeprazole (Prilosec), cimetidine (Tagamet), and voriconazole (Vfend).

Non-steroidal anti-inflammatory drugs (NSAIDs). Taking NSAIDs with Celexa may increase the risk of bleeding. Examples of these drugs include naproxen (Aliv), ibuprofen (Advil), and meloxicam (Mobic).

Anticoagulants and antiaggregants (blood thinners). Taking these drugs with Celexa may increase the risk of bleeding. Examples of blood thinners include clopidogrel (Plavix), warfarin (Coumadin), rivaroxaban (Xarelto), apixaban (Eliquis), and aspirin (Bayer, Ecotrin, Saint Joseph Low, and others).

Antipsychotics. Taking antipsychotics with Celexa may increase the risk of serotonin syndrome. Examples of these drugs include aripiprazole (Abilify) and quetiapine (Seroquel).

Certain oral antifungals. Taking Celexa with some antifungal medicines you take by mouth may increase the risk of heart rhythm problems while taking Celexa. Examples of these antifungals include ketoconazole and itraconazole.

The above list does not include all drugs that may interact with Celexa. Before starting treatment with Celexa, tell your doctor and pharmacist about all prescription and over-the-counter medicines you are taking. They can determine if they are safe to use with Celexa.

Elisabeth Scheffel, PharmD, BCACP, CDCES Answers represent the opinions of our medical experts. All content is for informational purposes only and should not be considered medical advice.

Registration data: Drink-Drink has made every effort to ensure that all information is accurate, complete and up to date.

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Frequently Asked Questions About Celexa Side Effects

Do I have a higher risk of side effects during the first week of taking Celexa?

Will I experience withdrawal side effects if I stop taking Celexa?

Does Celexa cause any long term side effects?

Do the side effects of Celexa change depending on the dose I take (10mg, 20mg or 40mg)?

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Sexual problems in women and men

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Weight gain or weight loss

What can help

Insomnia (trouble sleeping)

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Suicidal thoughts and behavior in children and young people

What can help

Allergic reaction

What can help

Celexa Warnings

Boxed Warning: Suicidal Thoughts and Behaviors in Children and Young Adults

Other warnings

Drinking alcohol and Celexa

Pregnancy and lactation while taking Celexa

What to ask your doctor

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