Pristiq reviews for menopause
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Most voted positive review
98 People found this comment helpful
I hate to break it to you folks, but you could not feel better hours after taking this for the first time. I have tried every kind of antidepressant known to man. This has worked. No side-effects, it took some time - but IT WORKS. Don't listen to all the negative reviews. Everyone has a different chemistry so what is deemed "horrible" for one means in no way, shape, or form that this is the ex...
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Most voted negative review
13 People found this comment helpful
i truly thought that there was a magic pill out there that would cure my depression and anxiety. i have been on 9 different medications since 1998 most recently Pristiq. NONE of the medications i have been on have helped because there is no magic pill. i am NOT telling anyone to stop their medications but i am saying (for most people out there) you have to face what is depressing you-- figure out ...
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SORT BYCondition: Depression
Overall rating 5.0
EffectivenessEase of UseSatisfactionI was in crisis with major depressive disorder I had tried over the past 25 years so many different medications which helped but not enough then with a new doctor she prescribed me pristiq after about a month or so what a difference my ability to keep up with responsibilities and also starting to be able function and do more is awesome what a difference!
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Fill 3Created with Sketch.Condition: Major Depressive Disorder
Overall rating 5.0
EffectivenessEase of UseSatisfactionI want to give credit where it's due and share my experience so that it might resonate and help others. It's been a year since my "crash" and no one is still sure exactly what caused it but I feel Pristiq (generic Desvenlafaxine) should get the credit for pulling me out of an 4month insomnia/OCD/Depression rabbithole that darn near killed me. Everyone shouts from the rooftop when something doesn't work..so I feel it's only fair to do the same when it does. Crash got so bad psychiatrist insisted I go in-patient (I did not want to go on it this was how I was gonna feel for the rest of my life..dig?) and even though this was the WORST experience of my life for half a month it was here that I was given Pristiq for the first time (altho NO credit to them IMO). They threw handfuls of pills down my throat without really bothering to check for interactions. The psychiatrist only spent 1-5 minutes with me everyday and when I asked for more time he ignored me. Therapy was a joke (kindergarten level coloring sessions w/ Dr. Phil pop psychology) and it repeated after 7 day!. Thrown in with some truly disturbed and violent people (several there under police court direction) with no safeguards..and staff DID NOT CARE! Never got any decent sleep cuz feared getting attacked in night by other in-patients. Wife finally got me discharged (this whole time I was "voluntary"..but they wouldn't let me go for 16 days) by threatening legal action (altho the real trick was that SHE was a nurse and knew what patient rights were and were not). I got home and I was a zombie for a month (in-patient passed out benzos like candy..be careful of this) while a dozen meds leeched from my body..BUT I kept taking Pristiq the whole and after 6 weeks I finally began to feel normal again. I NEVER thought I would ever feel normal again..but I did. It's been almost a year later and I'm still taking the lowest dose and it's working for me. In truth, I'm tired A LOT, I'm over-sleeping and I've gained a lot of weight. But this is where discipline and will power need to kick in and intelligently managing my day..BUT..I'm alive. If I had it to do over I would find a way to unplug from job and duties for 4-6 weeks and just STAY HOME, get family to take of you and experiment with meds. Also, go slow..doctors wanna increase dose after just 1 or 2 weeks but this is when nasty side effects can really kick in IMHO). I started off with Zoloft but it only made my (already present) insomnia even worse..and I am self employed so staying home meant no money coming in. UNDER NO CIRCUMSTANCES WILL I EVER ALLOW MYSELF TO GO INPATIENT AGAIN! The truly sad thing is I was told by several other "inmates" (who had been in and out of these many times) that this was one of the nicer facilities. Sadly, I believe them. With a small handful as an exception, I truly wish Karmic retribution on each and everyone of the doctors, nurse & techs involved with my inpatient stay. I was simply a piece of meat that had good insurance to them and they did not care if I lived or died, got better or hung myself. AVOID INPATIENT LIKE THE PLAGUE! (IMHO)Read More Read Less
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Fill 3Created with Sketch.Condition: Other
Overall rating 1.0
EffectivenessEase of UseSatisfactionI have GAD,DEPRESSION AND PTSD AND IBS. This medication was terrible. The first time I took it made me have headaches, nausea, jitters, increased anxiety, insomnia and diareah. This medication is supposed to help you with depression and anxiety not make it worse. I took a gene sight test and it's still not for me. If you are thinking of taking this medication I would think about it and take the time to research to weigh your pros and cons considering that their are no pros. But what I'm trying to say don't take this it will make you feel crummier than you already are now.Read More Read Less
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Fill 3Created with Sketch.Condition: Depression
Overall rating 4.7
EffectivenessEase of UseSatisfactionI’ve been on several different SSRI’s over the years and this is the first one to really work well for me. I’ve thought antidepressants have helped me in the past but now I realize I had set the bar so low for myself to feel okay. I’m able to work though things in therapy with clarity I haven’t been able to achieve in the past without benzos which affected my ability to work and be productive. I wish I could take this at night instead of at the beginning of the day since I’m more likely to forget then. The half life is shorter so if you miss a dose you definitely feel side effects from withdrawal pretty quickly. But if taken at the same time as prescribed every day that isn’t an issue. I would highly recommend it to people dealing with depression, particularly for people who have tried other antidepressants that haven’t worked for them in the past. Read More Read Less
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Fill 3Created with Sketch.Condition: Posttraumatic Stress Syndrome
Overall rating 1. 0
EffectivenessEase of UseSatisfactionI took one 50 mg tablet and will never take it again. The effects I experienced were extremely unpleasant. I felt dizzy, confused, disoriented, anxious and nauseous.
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Fill 3Created with Sketch.Condition: Bipolar Depression
Overall rating 5.0
EffectivenessEase of UseSatisfactionI spent years trying antidepressants with no success. Pristiq works. I will never stop the Pristiq because I know it provides the chemical that my brain is missing. It also took me years to be diagnosed with bipolar II depression (I do not have the highs as in bipolar I). Pristiq works for the depression. However I recently went through a mixed episode of severe anxiety and depression that was crippling for several months and a mood stabilizer (Lamotrogine (Lamictal)) was added. I wonder if others on Pristiq have the same type of depression and could also benefit from a mood stabilizer in addition to the Pristiq. Again, I know I will always take these meds and I am ok with that now.Read More Read Less
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Fill 3Created with Sketch.Condition: Posttraumatic Stress Syndrome
Overall rating 5.0
EffectivenessEase of UseSatisfactionThe first week of taking Pristiq, I experienced excessive sweating. After the first week, the sweating completely went away and it has been amazingly effective. Pristiq is the first mental disorder drug I’ve ever taken that actually helps me and has no side effects.
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Fill 3Created with Sketch.Condition: Extreme Apprehension or Fear of Social Interaction
Overall rating 5.0
EffectivenessEase of UseSatisfactionI used this for anxiety; specially social and generalized anxiety. the only side effects i had was dry mouth for the first month or so; initially I wasn't sure it was working so w my doctor's approval i went off and DAMN it had been working great LOL. I went right back on. I'm on a low dose so i do still have anxiety but it's no longer running my life
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Fill 3Created with Sketch.Condition: Major Depressive Disorder
Overall rating 5.0
EffectivenessEase of UseSatisfactionIt seemed to work for me. Im getting out of bed everyday and engaging with life without getting triggered. No side effects except hiccups the first few days
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Fill 3Created with Sketch.Condition: Major Depressive Disorder
Overall rating 5.0
EffectivenessEase of UseSatisfactionI've only been on this for a couple of weeks. I have tried every antidepressant on the market. The SSRI which are most of them have always made me worse. Sometimes I'd hit on one that didn't have many side effects but it didn't pull me out of it but I just decided that this was as good as it'll ever be. Then one day I thought there's got to be something that will help me. I started seeing a therapist did no good because it wasn't due to circumstances every thing was great it had to be a chemical imbalance. I have spent years in bed never wanted to go anywhere or do anything. I'm not like that. I don't like wasting time I like being productive but depression is the worst. Dr decided to do the DNA test it came back with only one antidepressant pristiq. I don't have anything to lose I just hoped I could stand side effects. THERE'S BEEN NO SIDE EFFECTS. I'M FEELING SO MUCH BETTER. I KNOW IT'S GONNA TAKE A LITTLE TIME TO WORK COMPLETELY. I LOOK FORWARD TO TAKING THIS JOURNEY WITH PRISTIQ. ????Read More Read Less
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Fill 3Created with Sketch.Condition: Depression
Overall rating 1.0
EffectivenessEase of UseSatisfactionPristiq was prescribed to me as I was feeling down from the pandemic, severe bushfires locally/climate change, an unplanned move interstate, and a significant career change all within the previous year. I had never taken an antidepressant and never will again. Pristiq nearly killed me. I ended up in emergency three times and sustained a fractured skull, broken and dislocated arm, and cranial hematoma. It completely flipped my life upside down for the short period of time I was on it and cost me the small amount of savings I had left after moving, because I was bedridden with severe vertigo from the injuries and unable to work. Pristiq caused the onset of fainting spells. I thought I was slipping over, but it kept happening and unfortunately I fell down a flight of stairs. It also caused the onset of severe and previously non-existent suicidal ideation and visions within a few weeks of being on it. I was assessed by a psychiatric team and told to keep taking it, despite it being completely out of character. Pristiq provided no benefit whatsoever. I experienced extreme depersonalisation and derealisation for the six weeks I was taking it. This horrible experiment that I allowed my doctor to trial resulted in months of debilitating illness that extended well beyond the time I was taking it and I had no support to come off it. I ended up quitting cold turkey and going through the bizarre withdrawals (surreal and disturbing nightmares, out of the blue agitation, insomnia, and mood swings). I would not recommend taking this drug to anybody.Read More Read Less
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Fill 3Created with Sketch.Condition: Depression
Overall rating 5.0
EffectivenessEase of UseSatisfactionI had really bad anxiety and low moods but this has been very beneficial and has eased my anxiety tremendously. I was previously on Lexapro and Wellbutrin which has a negative impact on me and seemed to not help as much. This did the trick so far. I still get anxious every once in a while but I am better able to handle it and it only lasts a couple of hours vs the whole day.
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Fill 3Created with Sketch.Condition: Major Depressive Disorder
Overall rating 3. 0
EffectivenessEase of UseSatisfactionI wanted to like this one so bad... It worked until it didn't. I felt my depression get better for a little bit but I'm terribly depressed now and I can't take it anymore. Switching to paxil now
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Fill 3Created with Sketch.Condition: "Change of Life" Signs
Overall rating 1.0
EffectivenessEase of UseSatisfactionWhat's the "End Game" for taking this? is it to always have to rely on this because I cant be Undepressed? I get to live a medicated half life? There's no surgery to relieve me of this condition. I cant talk my way out of it . So I guess in order to have a life I get to have a "fake" life/ medicated life with side effects, the issue is from within not a condition that can be "cut out" or operated on
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Fill 3Created with Sketch.Condition: Repeated Episodes of Anxiety
Overall rating 4.7
EffectivenessEase of UseSatisfactionIt took several months to become fully effective but now that I've stayed with it my daily anxiety and triggers have calmed down as well as depression/general well being. My only real negative is how quickly you feel the withdrawal the next day, it's enough to help remind me if I forget. Overall, I'd highly recommend. -- my main issues are depression, generalized anxiety, social sit, and IBS
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Fill 3Created with Sketch.Condition: Major Depressive Disorder
Overall rating 5.0
EffectivenessEase of UseSatisfactionWonderful med! Helped my depression immensely
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Fill 3Created with Sketch.Condition: Depression
Overall rating 1.0
EffectivenessEase of UseSatisfactionThis drug made me worse. Nervous and shaking. I have never experienced such bad side effects like this. Could only take it for 4 days and had to get off it.
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Fill 3Created with Sketch.Condition: Depression
Overall rating 3.3
EffectivenessEase of UseSatisfactionI took Pristiq for over 10 years. It was a great benefit in the early years and over time became a problem. Dosage was increased over the years to combat diminishing returns. Side effects included severe constipation from time to time, restless leg Syndrome and impacted my central sleep apnoea. I have now been off Pristiq for 6 months and although it was very good for me initially, it became a problem and I am now fearful of trying any other anti-depressants. My Advice from my experience - try it, but put a definite time limit on its use. 6 months to 2 years and no more. Make sure you can deal with restless leg syndrome and constipation.Read More Read Less
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Fill 3Created with Sketch.Condition: Depression
Overall rating 5.0
EffectivenessEase of UseSatisfactionI have been on antidepressants since the 1980s for depression and anxiety. This is the best one yet. Recently, my husband tried and failed on other meds. He was switched to desvenlafaxine and he's back to his normal self. I'm very happy.
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Fill 3Created with Sketch.Condition: Major Depressive Disorder
Overall rating 4.7
EffectivenessEase of UseSatisfactionworked extremely quickly, and had a massive impact. each med does something different for each person, it is not one size fits all. this one was absolutely amazing for me.
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Wyeth's Pristiq helps menopause hot flashes-trials
By Deena Beasley
4 Min Read
SAN DIEGO, May 8 (Reuters) - Wyeth's WYE. N experimental drug Pristiq alleviates symptoms of menopause such as hot flashes without a significant impact on sexual function, researchers said on Tuesday, but the degree of relief falls short of that seen with estrogen therapy.
Pristiq, an altered form of Wyeth’s top-selling anti-depressant Effexor, is awaiting U.S. Food and Drug Administration approval as a treatment for both hot flashes associated with menopause and depression in adults.
Trial results unveiled here at a meeting of the American College of Obstetricians and Gynecologists also showed that Pristiq helped with mood disturbances and sleep.
Wyeth expects to launch Pristiq as a treatment for hot flashes in the third quarter of this year. The new drug is expected to help fill the void in Wyeth’s sales that would emerge when Effexor loses its patent protection by 2010 and faces competition from cheaper generics.
A six-month trial involving 541 women suffering from moderate-to-severe hot flashes found that a 100 mg dose of Pristiq resulted in about a 60 percent reduction in symptoms after 12 weeks, compared with a drop of about 50 percent for women given a sugar pill. A 150 mg dose cut symptoms by 66 percent.
“You can get a 90 percent, or more, reduction in hot flashes with estrogens,” said Dr. Isaac Schiff, chief of obstetrics and gynecology at Massachusetts General Hospital in Boston. He was not involved in the Pristiq trials.
Wyeth is the maker of once-blockbuster hormone replacement therapy Premarin, sales of which have plummeted after hormone drugs were linked to a higher risk of breast cancer.
The high placebo effect seen in studies of Pristiq matches that seen in trials of hormone therapies, said study author Dr. David Archer, professor of obstetrics and gynecology at Eastern Virginia Medical School.
If approved, Pristiq would be the first non-hormonal treatment indicated for relief of vasomotor symptoms.
“For women who can’t take estrogens -- those with a history of breast cancer or who do not want to take estrogens for whatever reason -- this should be made available,” said Dr. Schiff.
An FDA decision on Pristiq was postponed to July after Wyeth decided to conduct trials aimed at reducing nausea by starting patients out at a lower 50 mg dose. A Wyeth spokeswoman said results from those trials will be presented at a medical meeting later this year.
Dr. Archer said side effects seen in the steady-dose trials of Pristiq included temporary nausea and dizziness.
Nausea “is thought to be due to giving a bigger dose initially,” he explained. As a result, the latest trials of the drug start patients out on a 50 mg dose before ratcheting up to 100 mg or 150 mg. The dosage is also tapered down when patients are taken off the drug, said Dr. Archer.
Pristiq, like Effexor, is a serotonin-norepinephrine reuptake inhibitor. Other common anti-depressants, like Pfizer’s Zoloft, are serotonin reuptake inhibitors.
As a dual reuptake inhibitor, the theory is that Pristiq would be a better option for depressed women who are transitioning through menopause and often are experiencing a fluctuation or decline in estrogen that may diminish both serotonin and norepinephrine functioning.
In addition, some anti-depressants have been associated with lower libido. A trial of Pristiq showed that a nonsignificant 4.2 percent of patients treated with the drug had problems like abnormal orgasm and decreased libido, compared with 1.3 percent of patients on placebo.
Wyeth is also studying Pristiq as a treatment for fibromyalgia, an under-treated chronic pain syndrome.
The drug will be manufactured at Wyeth’s Guayama, Puerto Rico, plant where the FDA is reinspecting the facilities to certify that past problems have been fixed.
((Reporting by Deena Beasley, editing by Richard Chang; Reuters Messaging: [email protected]@reuters.net; 1-213-955-6746)) Keywords: WYETH PRISTIQ
C Reuters 2007. All rights reserved. Republication or redistribution ofReuters content, including by caching, framing or similar means, is expresslyprohibited without the prior written consent of Reuters. Reuters and the Reuterssphere logo are registered trademarks and trademarks of the Reuters group ofcompanies around the world.nN01365560
What drugs to take for menopause in women 2021
Not everyone knows which drugs to use for menopause so that the therapy is non-hormonal. The so-called hot flashes are a feeling of warmth covering the body and accompanied by redness, sweating. These symptoms vary according to severity ranging from minor irritation to severe impairment of quality life, therefore menopause treatment non-hormonal drugs justified to improve the general condition.
Among the causes are:
· decrease in estrogen levels, which affects the center regulation of brain temperature, causing shivering;
other related health conditions, including thyroid disease, diabetes, hyperhidrosis, anxiety and panic disorders, obesity, hormonally active tumors, chronic infections, neurological disorders;
taking certain medications. These include antiestrogens: tamoxifen, aromatase inhibitors, toremifene, raloxifene and clomiphene, and gonadotropin-releasing hormone analogues, i.e. goserelin, leuprorelin and nafarelin.
Treatment of menopause with non-hormonal drugs
Non-hormonal drugs for menopause are effective for women.
Paroxetine (trade name Brisdelle is a non-hormonal therapy specifically approved for tides. This remedy is the most effective drug for menopause , which has been used for years for depression.
Gabapentin (brand name "Neurontin") - a medicine that is mainly used for seizures. Included in list best drugs for menopause by reviews of users. A systematic review confirmed that the 900 mg daily dose the day reduces the tides. The most common side effect is drowsiness, swelling of the lower extremities and weight gain. The discontinuation should be gradually over the course of a week.
The most common answer to the question, which drugs to take for menopause , is clonidine. It is a centrally acting alpha-adrenergic receptor agonist, which stimulates certain receptors in the brain, reduces blood pressure, prevents migraines, and is also needed as a drugs against menopause. Side effects include dry mouth, shortness of breath, dizziness, constipation, and sleep disturbance. stop reception if after four weeks there are no results. High doses should be gradually reduced to avoid an increase in blood pressure.
Antidepressants are recommended for those who cannot take hormonal preparations for menopause .
Venlafaxine (Effexor), desvenlafaxine (Pristiq), citalopram (Celexa) and escitalopram (Lexapro) are designed for depression, but studies show that it is also effective preparations for menopause .
Fluoxetine (Prozac) and sertraline (Zoloft) are also exploited as drugs for menopause , but do not work as well as the other antidepressants listed.
Phytoestrogens - herbal preparations for menopause "natural" or a "safer" alternative to hormones. They are found in foods nutrition, including soybeans, chickpeas, flaxseeds, lentils, grains, fruits, vegetables and red clover. Isoflavone supplements (example bada with menopause in women ), one of the types of phytoestrogens, you can buy in health food stores.
Many medicinal herbs are advertised how the best drugs for menopause by reviews of doctors . Among them is black cohosh, although there is no clinical evidence. their effectiveness. They may not be more cost-effective than placebos.
Which hormonal preparations to take with menopause in women ? Low dose vaginal estrogen best remedy for postmenopausal women with vaginal dryness or pain during sexual intercourse.
Fomin's clinic — a network of multidisciplinary clinics
During menopause, serious changes occur in the body, about which women usually know very little. In this article, we will debunk the most popular myths, and at the same time explain what menopause is, what to expect from it, and whether it is necessary to endure the unpleasant symptoms associated with it.
The age of onset of sexual activity does not affect the rate of menopause in any way. The timing of menopause is determined by genetics. You will most likely go through menopause around the same age as your mother.
To date, scientists know only one external factor, independent of heredity, that can bring menopause closer in otherwise healthy people - this is smoking. On average, smokers stop menstruating 2 years earlier than non-smokers.
This is not true. The menopause is a smooth physiological restructuring associated with a decrease in the level of sex hormones until the complete disappearance of menstruation. Changes in the hormonal background begin at about 40-50 years old, can last up to 8-10 years and take place in three stages.
Perimenopause . Normally, it begins at the age of 40-45 years and can last from 4 years to several months. At this time, a woman produces less and less female sex hormones - estrogens. At this time, menstruation becomes irregular, sometimes their character changes - the discharge becomes either unusually plentiful, or, conversely, scarce.
In the last year or two of perimenopause, the fall in estrogen levels accelerates. Approximately 40% of women experience menopausal symptoms for the first time at this time - due to biochemical and hormonal changes, they may become more irritable, experience hot flashes (an unexpected feeling of hotness and sweating), sleep disturbances, or even fall into depression.
Menopause . At this time, menstruation stops. However, it is possible to assert that this is menopause, and not a cycle failure, only after a woman has lived without menstruation for a whole year. At this time, menopause symptoms appear in 60-80% of women.
Postmenopausal . Comes after a year of menopause. At this time, for many women, menopausal symptoms subside. Unfortunately, at this stage, health problems associated with a lack of estrogens, such as osteoporosis, can appear.
With age, the level of sex hormones decreases in both women and men, so the term "male menopause" has the right to exist. At the same time, age-related hormonal changes in women occur differently than in men.
In women during the last period of perimenopause, the level of estrogen decreases quite sharply in just 1-2 years, so that this leads to a complete cessation of menstruation, that is, menopause. Although this is a natural physiological process, due to the gradual “turning off” of the usual hormonal background, women often experience unpleasant symptoms.
In men, testosterone levels begin to decline gradually from the age of 30. After this age, testosterone levels drop by about 1-2% each year. A sharp decrease in the level of sex hormones in men does not occur, so the "male menopause" most often goes without noticeable physical symptoms.
However, there are exceptions to every rule. In about 2.1% of men, the age-related decrease in the level of sex hormones leads to changes resembling the female menopause. True, "male menopause" is not usually considered a natural part of aging. According to British doctors, the age-related decline in testosterone levels is a disease that must be treated with hormone therapy.
Not really. Although the ability to have children decreases in perimenopause, the chance still remains. In order to definitely not get pregnant, you need to use contraceptives until a “guaranteed” menopause occurs, that is, at least a year must have passed since the last menstruation.
However, you shouldn't stop using condoms completely, even after menopause. Although it is no longer possible to become pregnant, there is still a risk of getting a sexually transmitted disease through unprotected sex with a new/non-regular partner.
Indeed, there is evidence that estrogen improves learning and memory in healthy women. But it is not a fact that the lack of estrogen is to blame for the forgetfulness of older women. Memory problems may be associated with age-related changes in the cardiovascular system. Because of this, the blood supply to the brain worsens in older people of both sexes.
As for hysteria, some menopausal women sometimes experience mood swings, may become more irritable and experience unreasonable anxiety. But sudden mood swings depend not only on hormones, so you can’t write them off solely on menopause.
The only menopausal symptom unequivocally associated with a decrease in the synthesis of sex hormones is hot flashes, which are experienced by 80% of women of different cultures. Fortunately, hot flashes that are too strong and too frequent can be managed with menopausal hormone therapy or non-hormonal treatment, which can be prescribed by your gynecologist.
Tooth decay is not associated with menopause but with the normal aging process. Unfortunately, the lack of estrogen leads to other problems, such as hair loss and dry skin, and in some people, menopause provokes muscle and joint pain. If you are faced with such manifestations, it is not necessary to endure them - you need to contact a gynecologist who will select the appropriate treatment for you.
43% of menopausal women lose interest in sex. But despite their age, more than half of women continue to do it! Another thing is that due to the lack of estrogen, sex may not be as pleasant as before.
According to a large American study, 39% of menopausal women complained of a lack of lubrication, 34% noted an inability to climax, 23% experienced no pleasure from sex, and 17% experienced pain during sex.
Fortunately, these problems can be overcome. To regain interest in sex, you can try to have it more often and do Kegel exercises to strengthen the muscles of the pelvic floor - this will help increase blood flow to the vagina and strengthen the muscles involved in orgasm.
Lack of lubrication can be compensated with lubricants, and interest in sex is often restored in women who start taking menopausal hormone therapy.
True, it must be taken into account that menopausal hormone therapy is not indicated for everyone. For example, there is evidence that hormone therapy harms rather than helps women over 60 years of age. Before starting treatment, you must always consult with your doctor.
The benefits of proper menopausal hormone therapy (MHT) far outweigh the risks. MHT relieves the discomfort of hot flashes, helps prevent osteoporosis-related fractures, and generally improves quality of life.
When hormone therapy was first introduced to relieve menopausal symptoms, there was evidence that it increased the risk of breast cancer and coronary heart disease.
However, subsequent studies have shown that if MHT is started immediately after the onset of menopause, it, on the contrary, reduces the risk of death from coronary heart disease and other causes, and also relieves menopausal symptoms and reduces the risk of fractures due to osteoporosis.
However, MHT is not suitable for everyone: for example, it is not suitable for women with severe liver disease, venous thrombosis, and breast cancer.