Information about wellbutrin

Bupropion (Wellbutrin) | NAMI: National Alliance on Mental Illness

Brand names:

Wellbutrin SR®
- Tablets: 100 mg, 150 mg, 200 mg
Wellbutrin XL®
- Tablets: 150 mg, 300 mg
Zyban®
- Tablets: 150 mg
Forfivo XL®
- Tablets: 450 mg
Aplenzin®
- Tablets: 174 mg, 348 mg, 522 mg
Bupropion hydrochloride
- Immediate release tablets: 75mg, 100 mg
- Sustained release tablets: 100 mg, 150 mg, 200 mg
- Extended release tablets: 150 mg, 300 mg
Bupropion hydrobromide
- Extended release tablets: 174 mg, 348 mg, 522 mg

Generic name: bupropion (byoo PRO pee on)

All FDA black box warnings are at the end of this fact sheet. Please review before taking this medication.

What Is Bupropion And What Does It Treat?

Bupropion is an antidepressant medication that works in the brain. It is approved for the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and to help people quit smoking (smoking cessation).

Symptoms of depression include:

Depressed mood - feeling sad, empty, or tearful
Feeling worthless, guilty, hopeless, and helpless
Loss of interest or pleasure in your usual activities
Sleep and eat more or less than usual (for most people it is less)
Low energy, trouble concentrating, or thoughts of death (suicidal thinking)
Psychomotor agitation (‘nervous energy’)
Psychomotor retardation (feeling like you are moving and thinking in slow motion)
Suicidal thoughts or behaviors

SAD is a type of depression that occurs mainly during the autumn-winter season. Although the common term SAD is now referred to as Major Depression with Seasonal Pattern, this fact sheet will continue to use SAD as it is more commonly known.

Bupropion may also be helpful when prescribed “off-label” for bipolar disorder, attention deficit hyperactivity disorder (ADHD, and sexual dysfunction due to SSRI antidepressants. “Off-label” means that it hasn’t been approved by the Food and Drug Administration for this condition. Your mental health provider should justify his or her thinking in recommending an “off-label” treatment. They should be clear about the limits of the research around that medication and if there are any other options.

What Is The Most Important Information I Should Know About Bupropion?

After starting bupropion, symptoms gradually decrease over a period of weeks. In MDD and SAD, sleep and other physical symptoms may improve before there is noticeable improvement in mood or interest in activities. Once symptoms are under control, MDD usually requires long-term treatment to help prevent the return of depressive symptoms. If you are using bupropion for SAD or smoking cessation, the length of your treatment may be shorter. With input from you, your health care provider will assess how long you will need to take the medicine.

Do not stop taking bupropion or change your dose without talking with your health care provider first.

Depression is also a part of bipolar illness. People with bipolar disorder who take antidepressants may be at risk for "switching" from depression into mania. Symptoms of mania include "high" or irritable mood, very high self-esteem, decreased need for sleep, pressure to keep talking, racing thoughts, being easily distracted, frequently involved in activities with a large risk for bad consequences (for example, excessive buying sprees).

Are There Specific Concerns About Bupropion And Pregnancy?

If you are planning on becoming pregnant, notify your health care provider to best manage your medications. People living with MDD who wish to become pregnant face important decisions, each with risks and benefits as they relate to how the illness, medications, and risks to the fetus may interact. Untreated MDD has risks to the fetus, as well as the mother. It is important to discuss the risks and benefits of treatment with your doctor and caregivers.

Bupropion has also been evaluated for smoking cessation during pregnancy and is recommended only after other therapies have failed.

Caution is advised with breastfeeding since bupropion does pass into breast milk.

What Should I Discuss With My Health Care Provider Before Taking Bupropion?

Symptoms of your condition that bother you most
If you have thoughts of suicide or harming yourself
Medications you have taken in the past for your condition, whether they were effective or caused any adverse effects
If you experience side effects from your medications, discuss them with your provider. Some side effects may pass with time, but others may require an adjustment in the medication.
Any other psychiatric or medical problems you have, including a history of bipolar disorder
All other medications you are currently taking and any medication allergies you have. This will help your prescriber assess for potential drug interactions.
Other non-medication treatment you are receiving (such as psychotherapy (i.e., talk therapy) or substance abuse treatment). Your provider can explain how these different treatments work with the medication.
If you are pregnant, plan to become pregnant, or are breastfeeding
If you drink alcohol or use drugs

How Should I Take Bupropion?

Bupropion hydrochloride is available in 3 different forms: immediate release (IR), sustained release (SR), and extended release (XL).

Bupropion IR is usually taken 2 or 3 times per day with 4-6 hours between doses. The dose usually ranges from 100 mg twice daily to 150 mg three times daily, with the last dose taken mid-afternoon.

Bupropion SR is usually taken twice daily in the morning and mid-afternoon. The dose usually ranges from 100 mg twice daily up to 200 mg twice daily.

Bupropion XL is usually taken once daily in the morning. The dose ranges from 150 mg to 450 mg.

Bupropion hydrobromide (Aplenzin®) is usually taken once daily in the morning. The dose ranges from 174 mg to 522 mg.

While there are dose ranges for each form, your health care provider will determine the form and dose that is right for you based on your response.

The dose for SAD is bupropion XL 150 mg once daily in the morning. The dose may be increased to 300 mg once daily.

The dose for smoking cessation is bupropion SR 150 mg once daily for 3 days and then twice daily for 7 to 12 weeks.

You should not take more than one product that contains bupropion, including the products that are used to quit smoking. Do not take more than your prescribed dose since higher doses may increase your risk of having a seizure. Since quickly increasing the dose of bupropion can cause seizures in some people, your doctor will slowly increase your dose.

You can take bupropion on an empty stomach or with food. The SR and XL forms should be swallowed whole — not chewed, crushed, or broken — so that the medication can work correctly in your body and to reduce the risk of serious side effects. The tablet shell from the SR and XL forms may appear in your feces.

Consider using a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member or friend to remind you or check in with you to be sure you are taking your medication.

What Happens If I Miss A Dose Of Bupropion?

For bupropion IR or SR, if you miss a dose, take it as soon as you remember. Take the remaining doses for the day at evenly spaced times at least 4 hours apart. DO NOT take 2 doses at once. You should not take more than your prescribed dose and doing so may increase your risk of having a seizure.

For bupropion XL, do not take an extra tablet to make up for the dose you forgot. Wait and take your next dose at your regular time the next day.

What Should I Avoid While Taking Bupropion?

Avoid drinking alcohol or using illegal drugs while you are taking bupropion because the beneficial effects of the medication may be decreased and the risk of seizures may be increased. If you are dependent on drugs or alcohol and would like to stop, consult your healthcare provider for help. Abruptly stopping these substances can result in a seizure, especially when taking bupropion.

What Happens If I Overdose With Bupropion?

If an overdose occurs, call your doctor or 911. You may need urgent medical care. You may also contact the poison control center at 1-800-222-1222.

What Are The Possible Side Effects Of Bupropion?

Common side effects

Headache, weight loss, dry mouth, trouble sleeping (insomnia), nausea, dizziness, constipation, fast heartbeat, and sore throat. These will often improve over the first week or two as you continue to take the medication.

Rare/serious side effects

Less than 10% of patients will experience skin rash, sweating, ringing in the ears, shakiness, stomach pain, muscle pain, thought disturbances, anxiety or angle closure glaucoma (symptoms of angle closure glaucoma may include eye pain, changes in vision, swelling or redness in or around eye).

Unlike many antidepressants, bupropion does not commonly cause sexual side effects and may be selected as an alternative treatment when antidepressant-induced sexual side effects are problematic. Sexual side effects include such problems as difficulty achieving orgasm or ejaculatory delay.

In general the risk of seizures due to bupropion is low. The risk of having a seizure increases with higher than recommended doses of bupropion, a history of seizures or head injury, tumor in the brain, severe liver disease, an eating disorder, alcohol or drug dependence, or taking other drugs that can also increase your risk of having a seizure.

There is a low risk of cardiovascular adverse events associated with stimulating agents, including bupropion. This risk increases if you have heart disease, high blood pressure, previous heart attack, or irregular heartbeat, or when used with transdermal nicotine replacement products. In these cases, a thorough cardiovascular evaluation is recommended before starting this medicine.

Are There Any Risks For Taking Bupropion For Long Periods Of Time?

To date, there are no known problems associated with long term use of bupropion. It is a safe and effective medication when used as directed.

What Other Medications May Interact With Bupropion?

Bupropion should not be taken with or within two weeks of taking monoamine oxidase inhibitors (MAOIs). These include phenelzine (Nardil®), tranycypromine (Parnate®), isocarboxazid (Marplan®), and selegiline (Emsam®).

There are several products with the active ingredient bupropion. Do not take more than one product that contains bupropion since this may increase your risk of having a seizure.

Certain medications may increase your risk of having a seizure when combined with bupropion. These include other antidepressants, antipsychotics, theophylline, isoniazid, tramadol, stimulants, steroids, hypoglycemic agents (including insulin), certain antibiotics (e.g., Cipro®), and abrupt discontinuation of benzodiazepines (e.g., Ativan®).

Notify your doctor and pharmacist if you are taking any of the following medications: phenytoin (Dilantin®), carbamazepine (Tegretol®, Equetro®), phenobarbital, cimetidine (Tagamet®), ritonavir (Norvir®), lopinavir (Kaletra™), nelfinavir (Viracept®), or efavirenz (Sustiva®). These medications can change the way your body reacts to bupropion.

Notify your doctor and pharmacist if you are taking any of the following medications: atomoxetine (Stratterra®), codeine, tamoxifen, tetrabenazine, thioridazine (Mellaril®), tramadol (Ultram®), or a tricyclic antidepressant. Bupropion can change the way your body reacts to these medications.

How Long Does It Take For Bupropion To Work?

Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.

Summary of FDA Black Box Warnings

Suicidal thoughts or actions in children and adults

Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients with major depressive disorder (MDD), both adult and pediatric, may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in behavior, whether or not they are taking antidepressant medications. This risk may persist until significant remission occurs.

In short-term studies, antidepressants increased the risk of suicidality in children, adolescents and young adults when compared to placebo. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24. Adults ages 65 and older taking antidepressants have a decreased risk of suicidality. Patients, their families and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or healthcare professional. All patients being treated with antidepressants for any indication should watch for and notify their healthcare provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.

Provided by

(December 2020)

©2020 The College of Psychiatric and Neurologic Pharmacists (CPNP) and the National Alliance on Mental Illness (NAMI). CPNP and NAMI make this document available under the Creative Commons Attribution-No Derivatives 4.0 International License. Last Updated: January 2016.

This information is being provided as a community outreach effort of the College of Psychiatric and Neurologic Pharmacists. This information is for educational and informational purposes only and is not medical advice. This information contains a summary of important points and is not an exhaustive review of information about the medication. Always seek the advice of a physician or other qualified medical professional with any questions you may have regarding medications or medical conditions. Never delay seeking professional medical advice or disregard medical professional advice as a result of any information provided herein. The College of Psychiatric and Neurologic Pharmacists disclaims any and all liability alleged as a result of the information provided herein.

Wellbutrin Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Warnings:

Bupropion is an antidepressant used to treat a variety of conditions, including depression, other mental/mood disorders, and smoking cessation. Antidepressants can help prevent suicidal thoughts/attempts and provide other important benefits. However, studies have shown that a small number of people (especially people younger than 25) who take antidepressants for any condition may experience new or worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. It is very important to talk with the doctor about the risks and benefits of antidepressant medication, even if treatment is not for a mental/mood condition.

Tell the doctor right away if you notice new or worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.

If you are using bupropion to quit smoking, stop taking bupropion and contact your doctor right away if you experience any of the symptoms listed above. Tell your doctor right away if you have any of these symptoms after stopping treatment.

Warnings:

Uses

Bupropion is used to treat depression. It can improve your mood and feelings of well-being. It may work by helping to restore the balance of certain natural chemicals (neurotransmitters) in your brain.

How to use Wellbutrin 75 Mg Tablet

Read the Patient Information Leaflet and Medication Guide available from your pharmacist before you start using bupropion and each time you get a refill. Consult your doctor or pharmacist if you have any questions.

Take this medication by mouth with or without food as directed by your doctor, usually three times daily. If stomach upset occurs, you may take this drug with food. It is important to take your doses at least 6 hours apart or as directed by your doctor to decrease your risk of having a seizure.

The manufacturer directs not to crush, cut, or chew the tablet before taking it. However, many similar drugs (immediate-release tablets) can be crushed, cut, or chewed. Follow your doctor's directions on how to take this medication.

Do not take more or less medication or take it more frequently than prescribed. Taking more than the recommended dose of bupropion may increase your risk of having a seizure.

The dosage is based on your medical condition and response to treatment. Your dose may be slowly increased to limit side effects such as sleeplessness, and to decrease the risk of seizures. To avoid trouble sleeping, do not take this medication too close to bedtime. Let your doctor know if sleeplessness becomes a problem.

Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same times each day.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.

It may take 4 or more weeks before you notice the full benefit of this drug. Continue to take this medication as directed by your doctor even after you feel better. Talk to your doctor if your condition does not improve or if it worsens.

Side Effects

Precautions

Before taking bupropion, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: seizures or conditions that increase your risk of seizures (including brain/head injury, brain tumors, arteriovenous malformation, eating disorders such as bulimia/anorexia nervosa), alcohol/drug dependence (including benzodiazepines, opioid pain medicines, cocaine and stimulants), diabetes, heart disease (such as congestive heart failure, high blood pressure, recent heart attack), kidney problems, liver problems (such as cirrhosis), personal or family history of psychiatric disorder (such as bipolar/manic-depressive disorder), personal or family history of suicide thoughts/attempts, personal or family history of glaucoma (angle-closure type).

This medication should not be used if you are suddenly stopping regular use of sedatives (including benzodiazepines such as lorazepam), drugs used to treat seizures, or alcohol. Doing so may increase your risk of seizures.

This drug may make you dizzy or affect your coordination. Alcohol or marijuana (cannabis) can make you more dizzy or affect your coordination. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Alcohol can also increase your risk of seizures. Talk to your doctor if you are using marijuana (cannabis).

Older adults may be more sensitive to the side effects of this drug, especially dizziness and memory loss. Dizziness can increase the risk of falling.

During pregnancy, this medication should be used only when clearly needed. Since untreated mental/mood problems (such as depression, seasonal affective disorder, bipolar disorder) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: codeine, pimozide, tamoxifen, thioridazine.

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Ask your doctor when to start or stop taking this medication.

This medication may interfere with certain medical/laboratory tests (including brain scan for Parkinson's disease, urine screening for amphetamines), possibly causing false results. Tell laboratory personnel and all your doctors you use this drug.

Does Wellbutrin 75 Mg Tablet interact with other drugs you are taking?

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Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: seizures, hallucinations, fast or slow heart rate, loss of consciousness.

Do not share this medication with others.

Psychiatric/medical checkups or tests such as blood pressure monitoring may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

If you miss a dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Bupropion tablets may have a strange odor. This is normal and the medication is still okay to use. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Bupropion gave criminal complications - Gazeta Kommersant No.

29 (6750) dated February 18, 2020 psychiatrists consider it a legal antidepressant. Astrakhan customs opened a large-scale drug smuggling case against Olga Kalinovskaya, suffering from a psychiatric illness, who received pills in the mail. The woman claims that she did not even order the medicine - the package was allegedly a New Year's gift from a friend who advised her on treatment. Experts point out that bupropion is not banned in Russia, but this does not interfere with judging for its purchase. nine0003

Photo: Sergey Mikheev, Kommersant / buy photo

Olga Kalinovskaya lived in Ukraine since 2008, where she was diagnosed with a depressive personality disorder. In 2012, an acquaintance of hers, a teacher who works with special children, suggested that the woman might also have attention deficit hyperactivity disorder (ADHD). She advised me to contact a friend from Norway who lives with ADHD himself and consults other patients remotely. He confirmed the diagnosis of Olga Kalinovskaya and recommended bupropion for treatment; she several times ordered the drug to Ukraine from an Indian pharmaceutical company without any problems. nine0003

Abroad Bupropion is completely legal and prescribed by doctors as an antidepressant or to help quit smoking. Foreign pharmaceutical companies produce bupropion tablets under different names: Zyban, Elontril, Wellbutrin. Until 2016, it was also sold in Russia, and the Ministry of Health even included it in the standards for the provision of medical care. But then the manufacturer left the Russian market and withdrew the license from the State Register of Medicines. By law, such drugs without a license can be bought and sold as dietary supplements. nine0014

In 2017, Olga Kalinovskaya returned to Volgograd with her husband and child to take care of her elderly mother. The woman passed a psychiatric commission, but Russian doctors did not confirm ADHD. She was given a different diagnosis (she asked not to disclose it to the media) and prescribed treatment. Ivan Martynikhin, a member of the executive committee of the Russian Society of Psychiatrists, told Kommersant that ADHD is poorly diagnosed in Russia: “Doctors do not know that it persists in adults. I see patients who come in with a depressive disorder, and ADHD is at the root.” nine0003
At the same time, the psychiatrist emphasized that one should not engage in self-examination: “Only in half of the patients who came to see me and complained of ADHD, the syndrome was actually confirmed.”

At the end of December 2019, Kalinovskaya received a notification about the delivery of an unknown package from India. She was detained at the post office - it turned out that the package contained 300 bupropion tablets. According to Mrs. Kalinovskaya, this was a complete surprise for her. Later, the woman found out that the same patient-consultant from Norway had sent the drug. “He didn’t warn me, he sent me pills for his money. He explained that he knew about my problem and just wanted to help,” said Olga Kalinovskaya. As a result, the Astrakhan customs opened a criminal case against Ms. Kalinovskaya under Part 3 of Art. 229.1 of the Criminal Code of the Russian Federation (drug smuggling on an especially large scale, the maximum penalty is up to 20 years in prison). Customs experts considered that the tablets contained "derivatives" of the illegal drug ephedron.

As Kommersant already told, in early 2019, Russian law enforcement agencies began to arrest citizens ordering drugs with bupropion in foreign online stores. The fact is that in Russian legislation since 2012 there is the concept of “derivatives of narcotic drugs” - this is the name of substances created by slightly changing the chemical formula of the drug. "Derivatives" are not listed as banned substances, but are still considered drugs. This wording appeared as part of the fight against new types of drugs, primarily "spice" - manufacturers quickly changed parts of the formula, which made it possible for some time to sell the drug without the threat of punishment. However, lawyers and narcologists already then criticized the idea of “derivatives” for legal uncertainty: they warned that sooner or later legal pharmaceuticals would fall under the ban. nine0003
There are already about ten criminal cases of bupropion smuggling, at least two people are in jail.

At the same time, the Russian Society of Psychiatrists (ROP) published an official conclusion in August 2019 that bupropion is not a drug and does not lead to dependence. Ivan Martynikhin, a member of the executive committee of the ROP, said that patients applied to the society with a request to include bupropion in clinical recommendations. The psychiatrist told Kommersant that the drug has practically no analogues and "kills two birds with one stone: bupropion is good in the treatment of depression and affects the cause - attention deficit hyperactivity disorder." Ivan Martynikhin noted that bupropion does not have severe side effects, which is important for patients with bipolar depression. Moreover, the drug can be prescribed in addition to the main drugs to correct side effects. nine0003
Legal consultant on drug-related cases, expert of the Institute of Human Rights Arseniy Levinson draws attention to the fact that no Russian legal act prohibits bupropion for circulation in the Russian Federation, nowhere is it officially indicated that it is considered a drug. “If a person does not read the news, then there is no way for him to know that bupropion is recognized by the police as a derivative of ephedron,” says Mr. Levinson. “Obviously, such a person cannot commit smuggling, a crime involving direct intent. In other words, the person must know that he is committing a crime and desire it. How could Olga Kalinovskaya know that the medicine she freely bought in Ukraine suddenly turned out to be a drug in Russia?” According to him, "the authorities stubbornly ignore" the problem of criminal liability for "derivatives". Mr. Levinson participates in the work of the Duma working group on improving anti-drug legislation; summer 2019years he spoke there about the situation with bupropion. “The representative of the Ministry of Internal Affairs said that they are aware of the problem, that the police are humanely sorry for those who are persecuted for purchasing medicine for medical reasons, but nothing needs to be changed,” said Arseniy Levinson.

“As a result, I face 20 years in prison for inaccuracies in the legislation,” says Olga Kalinovskaya.

Recall that the first criminal case on the smuggling of bupropion was initiated in April 2019 by the Ural customs against Daria Belyaeva, who ordered an antidepressant from Poland. As Irina Ruchko, the girl's lawyer, told Kommersant, in January 2020 the case was returned for additional investigation for the third time - with the wording that the investigation "did not specify the circumstances of socially dangerous acts." According to her, now the investigator intends to send several requests: “At least, to the medical institution where Daria was treated - to find out what drugs she was prescribed in connection with the disease. And to the Ministry of Health - to find out the attitude of the department towards bupropion. nine0003
The lawyer said that the investigator himself became the object of a departmental check: “Initially, the defense was acquainted with the decision on the appointment of an examination on bupropion, where the expert was asked five questions. And then the same decision appeared in the case file, only with three questions. In simple terms, this means that the investigator replaced one decision with another.” The lawyer sent a petition, after which the Investigative Committee checked the actions of the investigator. “The results are not yet known to me, but I very much doubt that a criminal case will be initiated,” she said. nine0003
During the investigation, Darya Belyaeva was assigned an additional psychiatric examination - the girl was declared insane. “If the court concludes that she is guilty, then she will be sent to compulsory outpatient treatment,” the lawyer explained. “That is, in any case, she is not threatened with a colony now. But this situation puts pressure on her - after all, she already had a serious illness. Of course, it is not easy for her to bear it. “Let's hope that the case will be dismissed without trial on rehabilitative grounds,” says Arseniy Levinson. “It is absolutely obvious that there is no public danger in the actions of a patient who acquires a medicine legal all over the world for medical use.” nine0003
Elizaveta Lamova, Alexander Chernykh

The article came by parcel – Kommersant Krasnoyarsk

Photo: Sergey Mikheev, Kommersant

Photo: Sergey Mikheev, Kommersant

In Kuzbass, law enforcers opened a criminal case on drug smuggling because of the purchase of the antidepressant bupropion, used to treat mental disorders. The drug from India was ordered by 28-year-old resident of Novokuznetsk Renard A., who suffers from a mental illness. He is currently serving as a witness in the case. It should be noted that at the end of 2021, the investigation stopped the criminal prosecution of Daria Belyaeva, a resident of Yekaterinburg. The girl ordered from Poland the popular Elontril drug containing bupropion, which in Russia was recognized as a “derivative” of the illegal drug ephedron. nine0047

Kemerovo customs opened a criminal case on drug smuggling due to the purchase of the antidepressant bupropion in a foreign online store. The events described in the materials of the investigation took place on January 10. As Arseniy Levinson, a legal consultant on drug-related cases, told Kommersant-Siberia, in one of the post offices of Novokuznetsk, law enforcement officers detained the mother of Renar A. (later she was released), who came to receive a package from India with the drug bupropion. The parcel contained about 500 150 mg tablets, which would have been enough for her son, who suffers from a mental illness, for several months. nine0003
According to Arseny Levinson, Renard A. has been under the supervision of psychiatrists for several years. Due to illness, he was released from military service and had to leave his job. Of the many drugs, only bupropion helped the patient: he became ill from SSRIs and aripiprazole, and sulpiride did not give the desired effect. “The psychiatrists with whom he consulted suggested the dosage, but they could not officially recommend this drug, since it was excluded from the state register of medicines,” said Mr. Levinson, noting that until 2016 this drug was freely sold in Russia under the trade name Wellbutrin. nine0003
According to Arseniy Levinson, without the necessary drug, Renard A. began to feel much worse, so he decided to order the drug in an Indian online store.

On Wednesday, January 19, Renard A. and his mother were summoned for questioning at the customs. “A criminal case has been initiated under Part 3 of Art. 229.1 of the Criminal Code of the Russian Federation (smuggling of narcotic drugs on an especially large scale), but my client was interrogated as a witness. In this status, no one will introduce us to any intermediate documents. In this we see a trick on the part of the investigation. As the operational officer explained to me, there is a certificate from the forensic center of the Internal Affairs Directorate stating that this drug is a narcotic,” lawyer Olga Koinova told Kommersant-Siberia. The lawyer noted that the criminal case was initiated on the fact, and not against a specific person. It was not possible to get a comment from the investigating authorities. nine0003
Lawyer Arseniy Levinson notes that the circumstances of the case confirm that Renard A. purchased exactly the drugs, and not narcotic drugs and their derivatives. “I believe that in the press he watched the case of Darya Belyaeva, who for several years of investigation was not prosecuted, the court returned her case to the prosecutor's office, and then she was completely rehabilitated. Consequently, in relation to bupropion, law enforcement agencies made a mistake,” said Mr. Levinson. In his opinion, the lack of intent to smuggle is confirmed by other circumstances. For example, the fact that Renard A. made an order to his address, called the post office and was interested in the shipment. nine0003
As Kommersant wrote, in December last year, the investigation stopped the criminal prosecution of 26-year-old resident of Yekaterinburg Darya Belyaeva. In 2019, the girl ordered from Poland the popular Elontril drug containing bupropion, which in Russia was recognized as a “derivative” of the illegal drug ephedron. She acquired the medicine on the recommendation of a doctor for the treatment of schizotypal personality disorder, but the investigation accused her of buying and smuggling drugs. The Russian Society of Psychiatrists, during the trial of Darya Belyaeva, prepared an official conclusion that bupropion is not a drug. Doctors said that the drug does not cause euphoria, and its use does not lead to dependence. The lawyer of Darya Belyaeva then said that in the process of correcting the criminal procedural violations of the case materials pointed out by the court, the investigation concluded that there was no evidence of the girl's guilt.
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