Vyvanse adverse effects
What are Common Vyvanse® Side Effects? For Adult ADHD
MEDICATION GUIDE
(lisdexamfetamine dimesylate)
Capsules and Chewable Tablets, CII
What is the most important information I should know about VYVANSE?
VYVANSE may cause serious side effects, including:
- Abuse and dependence. VYVANSE, other amphetamine containing medicines, and methylphenidate have a high chance for abuse and may cause physical and psychological dependence. Your healthcare provider should check you or your child for signs of abuse and dependence before and during treatment with VYVANSE.
- Tell your healthcare provider if you or your child have ever abused or been dependent on alcohol, prescription medicines, or street drugs.
- Your healthcare provider can tell you more about the differences between physical and psychological dependence and drug addiction.
- Heart-related problems including:
- sudden death, stroke, and heart attack in adults
- sudden death in children who have heart problems or heart defects
- increased blood pressure and heart rate
Your healthcare provider should check you or your child carefully for heart problems before starting treatment with VYVANSE. Tell your healthcare provider if you or your child have any heart problems, heart defects, high blood pressure, or a family history of these problems.
Your healthcare provider should check your or your child’s blood pressure and heart rate regularly during treatment with VYVANSE.
Call your healthcare provider or go to the nearest hospital emergency room right away if you or your child have any signs of heart problems such as chest pain, shortness of breath, or fainting during treatment with VYVANSE.
- Mental (psychiatric) problems, including:
- new or worse behavior and thought problems
- new or worse bipolar illness
- new psychotic symptoms (such as hearing voices, or seeing or believing things that are not real) or new manic symptoms
Tell your healthcare provider about any mental problems you or your child have or about a family history of suicide, bipolar illness, or depression.
Call your healthcare provider right away if you or your child have any new or worsening mental symptoms or problems during treatment with VYVANSE, especially hearing voices, seeing or believing things that are not real, or new manic symptoms.
What Is VYVANSE?
VYVANSE is a central nervous system (CNS) stimulant prescription medicine used for the treatment of:
- Attention Deficit Hyperactivity Disorder (ADHD) in adults and children 6 years of age and older. VYVANSE may help increase attention and decrease impulsiveness and hyperactivity in people with ADHD.
- Moderate to severe binge eating disorder (BED) in adults. VYVANSE may help reduce the number of binge eating days in people with BED.
VYVANSE is not for use in children under 6 years of age with ADHD.
VYVANSE is not for weight loss. It is not known if VYVANSE is safe and effective for the treatment of obesity.
It is not known if VYVANSE is safe and effective for use in children with BED.
VYVANSE is a federally controlled substance (CII) because it contains lisdexamfetamine dimesylate that can be a target for people who abuse prescription medicines or street drugs. Keep VYVANSE in a safe place to protect it from theft.
Never give your VYVANSE to anyone else because it may cause death or harm them. Selling or giving away VYVANSE may harm others and is against the law.
Do not take VYVANSE if you or your child are:
- allergic to amphetamine products or any of the ingredients in VYVANSE. See the end of this Medication Guide for a complete list of ingredients in VYVANSE.
- taking, or have stopped taking in the last 14 days, a medicine called a Monoamine Oxidase Inhibitor (MAOI).
- being treated with the antibiotic linezolid or intravenous methylene blue.
Before taking VYVANSE, tell your healthcare provider about all medical conditions, including if you or your child:
- have heart problems, heart defects, or high blood pressure
- have mental problems including psychosis, mania, bipolar illness, or depression or have a family history of suicide, bipolar illness, or depression
- have circulation problems in fingers and toes
- are pregnant or plan to become pregnant.
VYVANSE may harm the unborn baby.- There is a pregnancy registry for females who are exposed to VYVANSE during pregnancy. The purpose of the registry is to collect information about the health of females exposed to VYVANSE and their baby. If you or your child becomes pregnant during treatment with VYVANSE, talk to your healthcare provider about registering with the National Pregnancy Registry for Psychostimulants at 1-866-961-2388 or visit online at https://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/adhd-medications/.
- are breastfeeding or plan to breastfeed. VYVANSE passes into breast milk. You should not breastfeed during treatment with VYVANSE. Talk to your healthcare provider about the best way to feed the baby during treatment with VYVANSE.
Tell your healthcare provider about all the medicines that you or your child take
, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
VYVANSE can affect the way other medicines work and other medicines may affect how VYVANSE works. Taking VYVANSE with other medicines can cause serious side effects. Sometimes the doses of other medicines will need to be changed while taking VYVANSE.
Especially tell your healthcare provider if you or your child take:
| selective serotonin reuptake inhibitors (SSRIs) | serotonin norepinephrine reuptake inhibitors (SNRIs) |
| medicines used to treat migraine headaches called triptans | tricyclic antidepressants |
| lithium | fentanyl |
| tramadol | tryptophan |
| buspirone | St. John’s Wort |
Keep a list of all medicines to show your healthcare provider and pharmacist when you get a new medicine. Your healthcare provider will decide if VYVANSE can be taken with other medicines.
Do not start any new medicine during treatment with VYVANSE without talking to your healthcare provider first.
How should VYVANSE be taken?
- Take VYVANSE exactly as prescribed by your healthcare provider.
- Your healthcare provider may change the dose if needed.
- Take VYVANSE 1 time each day in the morning with or without food.
- Your healthcare provider may sometimes stop VYVANSE treatment for a while to check ADHD or BED symptoms.
- VYVANSE comes in capsules or chewable tablets.
Taking VYVANSE Capsules:
- VYVANSE capsules may be swallowed whole.
- If VYVANSE capsules cannot be swallowed whole, the capsule may be opened and the entire contents sprinkled onto yogurt, or poured into water or orange juice.
- Using a spoon, break apart any powder that is stuck together. Stir the VYVANSE powder and yogurt, water, or orange juice until they are completely mixed together.
- Swallow all the yogurt, water, or orange juice mixture right away. Do not store the yogurt, water, or orange juice mixture.
- It is normal to see a filmy coating on the inside of your glass or container after you eat or drink all the VYVANSE mixture.
Taking VYVANSE Chewable Tablets:
- Chew VYVANSE tablets completely before swallowing.
If you or your child take too much VYVANSE, call your healthcare provider or poison control center at 1-800-222-1222 or go to the nearest hospital emergency room right away.
What should I avoid while taking VYVANSE?
Do not drive, operate machinery, or do other dangerous activities until you know how VYVANSE affects you.
What are possible side effects of VYVANSE?
VYVANSE may cause serious side effects, including:
- See "What is the most important information I should know about VYVANSE?"
- Slowing of growth (height and weight) in children. Children should have their height and weight checked often during treatment with VYVANSE.
VYVANSE treatment may be stopped if your child is not growing or gaining weight. - Circulation problems in fingers and toes (Peripheral vasculopathy, including Raynaud’s phenomenon). Signs and symptoms may include:
- Fingers or toes may feel numb, cool, painful
- Fingers or toes may change color from pale, to blue, to red
Tell your healthcare provider if you or your child have numbness, pain, skin color change, or sensitivity to temperature in your fingers or toes.
Call your healthcare provider right away if you or your child have any signs of unexplained wounds appearing on fingers or toes during treatment with VYVANSE.
- Serotonin Syndrome. A potentially life-threatening problem called serotonin syndrome may happen when VYVANSE is taken with certain other medicines. Stop taking VYVANSE and call your healthcare provider or go to the nearest hospital emergency room right away if you or your child develop any of the following signs and symptoms of serotonin syndrome:
| agitation | fast heartbeat |
| flushing | seizures |
| coma | sweating |
| loss of coordination | confusion |
| dizziness | tremors, stiff muscles, or muscle twitching |
| seeing or hearing things that are not real (hallucination) | changes in blood pressure |
| high body temperature (hyperthermia) | nausea, vomiting, diarrhea |
The most common side effects of VYVANSE in children 6 to 17 years old and adults with ADHD include:
| loss of appetite (anorexia) | anxiety |
| decreased appetite | weight loss |
| diarrhea | dizziness |
| dry mouth | irritability |
| trouble sleeping | nausea |
| stomach pain | vomiting |
The most common side effects of VYVANSE in adults with BED include:
| dry mouth | trouble sleeping |
| decreased appetite | increased heart rate |
| constipation | feeling jittery |
| anxiety | |
These are not all the possible side effects of VYVANSE.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
How should I store VYVANSE?
- Store VYVANSE in a safe place (like a locked cabinet) and in a tightly closed container at room temperature between 68°F to 77°F (20°C to 25°C).
- Protect VYVANSE from light.
- Dispose of remaining, unused, or expired VYVANSE by a medicine take-back program at authorized collection sites such as retail pharmacies, hospital or clinic pharmacies, and law enforcement locations. If no take-back program or authorized collector is available, mix VYVANSE with an undesirable, nontoxic substance such as dirt, cat litter, or used coffee grounds to make it less appealing to children and pets. Place the mixture in a container such as a sealed plastic bag and throw away (discard) VYVANSE in the household trash.
Keep VYVANSE and all medicines out of the reach of children.
General information about the safe and effective use of VYVANSE.
Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use VYVANSE for a condition for which it was not prescribed. Do not give VYVANSE to other people, even if they have the same symptoms that you have. It may harm them and it is against the law. You can ask your pharmacist or healthcare provider for information about VYVANSE that is written for health professionals.
What are the ingredients in VYVANSE?
Active Ingredient: lisdexamfetamine dimesylate
Capsule Inactive Ingredients: microcrystalline cellulose, croscarmellose sodium, and magnesium stearate. The capsule shells (imprinted with S489) contain gelatin, titanium dioxide, and one or more of the following: FD&C Red #3, FD&C Yellow #6, FD&C Blue #1, Black Iron Oxide, and Yellow Iron Oxide.
Chewable Tablet Inactive Ingredients: colloidal silicon dioxide, croscarmellose sodium, guar gum, magnesium stearate, mannitol, microcrystalline cellulose, sucralose, artificial strawberry flavor.
Distributed by: Takeda Pharmaceuticals America, Inc., Lexington, MA 02421.
VYVANSE® and the VYVANSE Logo® are registered trademarks of Takeda Pharmaceuticals U.S.A., Inc.
©2022 Takeda Pharmaceuticals U.S.A., Inc. All rights reserved.
For more information, go to www.vyvanse.com or call 1-877-TAKEDA-7 (1-877-825-3327).
This Medication Guide has been approved by the U.S. Food and Drug Administration.
Revised: 10/2021
SPI-0340 Reformatted for US-LIS-1284
Vyvanse® Adverse Effects and Safety Profile for ADHD
STUDY 303
IN ADULTS
Adverse reactions reported by ≥2% of adult patients taking Vyvanse and at least twice the incidence in patients taking placebo in Study 303, the 4-week, parallel-group, pivotal clinical study (N=420).
1| ADVERSE REACTIONS | VYVANSE (n=358) | PLACEBO (n=62) |
|---|---|---|
| Decreased Appetite | 27% | 2% |
| Insomnia | 27% | 8% |
| Dry Mouth | 26% | 3% |
| Diarrhea | 7% | 0% |
| Nausea | 7% | 0% |
| Anxiety | 6% | 0% |
| Anorexia | 5% | 0% |
| Feeling Jittery | 4% | 0% |
| Agitation | 3% | 0% |
| Increased Blood Pressure | 3% | 0% |
| Hyperhidrosis | 3% | 0% |
| Restlessness | 3% | 0% |
| Decreased Weight | 3% | 0% |
| Dyspnea | 2% | 0% |
| Increased Heart Rate | 2% | 0% |
| Tremor | 2% | 0% |
| Palpitations | 2% | 0% |
Six percent (21/358) of Vyvanse-treated adult patients discontinued due to adverse reactions compared to 2% (1/62) of placebo-treated patients.
The most frequently reported adverse reactions (1% or more and twice the rate of placebo) were insomnia (8/358; 2%), tachycardia (3/358; 1%), irritability (2/358; 1%), hypertension (4/358; 1%), headache (2/358; 1%), anxiety (2/358; 1%), and dyspnea (3/358; 1%). Less frequently reported adverse reactions (less than 1% or less than twice the rate of placebo) included palpitations, diarrhea, nausea, decreased appetite, dizziness, agitation, depression, paranoia, and restlessness.
In the adult population, erectile dysfunction was observed in 2.6% of males who took Vyvanse and 0% who took placebo; decreased libido was observed in 1.4% of subjects who took Vyvanse and 0% who took placebo.
STUDY 301
IN CHILDREN
Adverse reactions reported by ≥2% of pediatric patients (6-12 years of age) taking Vyvanse and at least twice the incidence in patients taking placebo in Study 301, the 4-week, parallel-group, pivotal clinical study (N=290).
1| ADVERSE REACTIONS | VYVANSE (n=218) | PLACEBO (n=72) |
|---|---|---|
| Decreased Appetite | 39% | 4% |
| Insomnia | 22% | 3% |
| Upper Abdominal Pain | 12% | 6% |
| Irritability | 10% | 0% |
| Vomiting | 9% | 4% |
| Decreased Weight | 9% | 1% |
| Nausea | 6% | 3% |
| Dry Mouth | 5% | 0% |
| Dizziness | 5% | 0% |
| Affect Lability | 3% | 0% |
| Rash | 3% | 0% |
| Pyrexia | 2% | 1% |
| Somnolence | 2% | 1% |
| Tic | 2% | 0% |
| Anorexia | 2% | 0% |
Eight percent (18/218) of Vyvanse-treated pediatric patients discontinued due to adverse reactions compared to 0% (0/72) of placebo-treated patients.
The most frequently reported adverse reactions (1% or more and twice the rate of placebo) were ECG voltage criteria for ventricular hypertrophy, tic, vomiting, psychomotor hyperactivity, insomnia, decreased appetite, and rash (2 instances for each adverse reaction, ie, 2/218 [1%]). Less frequently reported adverse reactions (less than 1% or less than twice the rate of placebo) included upper abdominal pain, dry mouth, decreased weight, dizziness, somnolence, logorrhea, chest pain, anger, and hypertension.
STUDY 305
IN ADOLESCENTS
Adverse reactions reported by ≥2% of adolescent patients (13-17 years of age) taking Vyvanse and at least twice the incidence in patients taking placebo in Study 305, the 4-week, parallel-group, pivotal clinical study (N=310).
1| ADVERSE REACTIONS | VYVANSE (n=233) | PLACEBO (n=77) |
|---|---|---|
| Decreased Appetite | 34% | 3% |
| Insomnia | 13% | 4% |
| Decreased Weight | 9% | 0% |
| Dry Mouth | 4% | 1% |
| Palpitations | 2% | 1% |
| Anorexia | 2% | 0% |
| Tremor | 2% | 0% |
Three percent (7/233) of Vyvanse-treated adolescent patients discontinued due to adverse reactions compared to 1% (1/77) of placebo-treated patients.
The most frequently reported adverse reactions (1% or more and twice the rate of placebo) were decreased appetite (2/233; 1%) and insomnia (2/233; 1%). Less frequently reported adverse reactions (less than 1% or less than twice the rate of placebo) included irritability, dermatillomania, mood swings, and dyspnea.
what you need to know - Drink-Drink
Although not common, Vivanse can cause long-term side effects. This includes side effects that may persist even after the end of treatment, or side effects that occur after taking the drug for a long time.
If you have any questions about possible long-term side effects of Vivanse, talk to your doctor or pharmacist.
Vyvanse is used to treat attention deficit hyperactivity disorder (ADHD) in children 6 years of age and older. Children may be more prone to certain side effects than adults.
Studies have also reported sudden changes in emotion or mood in children aged 6 to 12 years who took Vivanse.
Examples of these types of changes may include uncontrollable crying or laughing at inappropriate times. Emotional or mood changes have not been reported in people aged 13 years and older who took Vivanse during the studies.
Vivanse may cause growth retardation (height and weight) in children. Your child's doctor will closely monitor their height and weight and compare them to the average height for your child's age. If they notice signs of growth retardation, your child's doctor may temporarily or permanently stop taking Vivanse.
If you have any questions about Vivanse side effects in children, talk to your child's doctor or pharmacist.
Frequently Asked Questions about Vivanse Side Effects
Get answers to some frequently asked questions about Vivanse side effects.
Can Vivanse's side effects vary depending on the strength of my dose (10mg, 20mg, 30mg, 40mg, 50mg, 60mg, 70mg)?
It is possible. For example, studies have shown that weight loss is more likely at higher doses of Vivanse.
These studies did not always compare side effects at different dosages of Vivanse, so it is not known if other side effects may differ depending on the dosage.
If you experience side effects from taking Vivanse, lowering the dose may help reduce the side effect. But you should not change your dose of Vivanse unless your doctor tells you to do so. Always take Vivanse exactly as directed by your doctor.
If you have any other questions about how your dose may affect the risk of side effects, talk to your doctor or pharmacist.
Does Vyvanse cause anger or other emotional side effects?
Yes, Vivanse can cause emotional side effects, including anger.
People who took Vivanse reported certain emotional side effects in studies, including:
- anger
- depression*
- irritability
- extreme excitement and energy)
- mood changes
If you are concerned about the emotional side effects of Vivanse, talk to your doctor or pharmacist.
They can discuss how to treat these side effects.
How long do the side effects of Vivance last?
In many cases, the side effects caused by Vivanse are supposed to be temporary. And mild side effects often go away on their own or are easy to treat.
But if you have any symptoms that persist or bother you, talk to your doctor or pharmacist. They may suggest stopping Vivanse treatment and switching to another drug.
Side effects explained
Find out more about some of the side effects Vivanse may cause.
Sleep problems
Sleep problems may occur during treatment with Vyvance. Sleep problems reported in studies of the drug included insomnia (trouble sleeping) and nightmares. Insomnia was one of the most common side effects of Vivanse's drug. In rare cases, people have stopped taking Vivanse due to insomnia.
Insomnia has been more common in adults in studies, but has also been reported in children treated with Vivanse.
It is important to note that sleep problems can also be a symptom of serious side effects that Vivanse can cause.
Examples of these serious side effects include psychiatric disorders such as mania, depression and psychosis.
What can help
Vyvanse is a central nervous system stimulant that may keep you awake if taken later in the day. To prevent sleep problems such as insomnia, avoid taking your dose in the afternoon while taking Vivanse. Instead, take Vivanse in the morning.
If you have trouble sleeping while taking Vivanse, talk to your doctor. They may offer treatment for this side effect, which may include new prescription or over-the-counter medications. Or they may force you to stop taking Vivanse and switch to another treatment for your condition.
Headache
Some people may experience headaches during treatment with Vivanse. This side effect has been rare in studies, but some people have stopped taking Vivanse due to headaches.
What can help
Vivanse headaches can go away on their own. But if you experience headaches that bother you or don't go away, talk to your doctor or pharmacist.
They may suggest treatment for this side effect, such as a new prescription or over-the-counter drug. Or they may suggest that you stop taking Vivanse and try another treatment for your condition.
Depression
In some cases, depression may occur when using Vivanse. Studies have reported depression in people taking Vivanse, but this was not common.
Symptoms of depression may include:
- changes in appetite
- feelings of agitation or anxiety
- feelings of guilt or worthlessness
- loss of interest in activities you normally enjoy
- help you sleep too much or too little What can be done
- aggressive or hostile behavior
- excessive sweating
- heavy breathing
- high blood pressure
- sleep problems, including insomnia
- Thoughts of hurting yourself or others
- skin rash
- itching
- redness (temporary warmth, redness, or increased skin color)
- swelling under the skin, usually on the eyelids, lips, arms, or legs
- swelling of the mouth, tongue, or throat that makes breathing difficult
- what dose of the drug you were taking when you had the side effect
- how soon after starting this dose you had the side effect
- what were your symptoms due to for a side effect
- how it affected your daily activities
- what other medications you also took
- any other information you think is important
- What are the side effects of Vivanse compared to other medicines that might help my condition?
- Can Vivanse cause sexual side effects?
- If I get side effects while taking Vivanse, will a lower dose help?
- severe fatigue (low energy)
- depression
- severe cravings
- mood changes
- chills
- LEADING ATTATITION
- Loss of appetite
- Loss weight
- Nausea
- Pain in the upper stomach 9003
- Insomnia
- Irritability
- Anxiety
- Reduced appetite
- Card
- Dry mouth
- Ligue pulse
- Insomnia
- Axiety
- SENTERS FAURITION
- Psychiatric problems such as anxiety, aggression or mania Neurological disorders such as tics, cramps or serotonin syndrome
- problems with the heart of the heart with the heart of the heart with the heart , heart attack and sudden death in people with heart problems
- Circulatory problems such as high blood pressure, stroke, damage to peripheral blood vessels, discoloration of the skin and Raynaud's phenomenon
- Severe allergic reactions
- Dependence, drug abuse and withdrawal symptoms upon abrupt discontinuation
- Plan your schedule : Schedule the most important activities of the day for the hours when Vyvanse is most active in the body. Schedule an extended break around the time of day that a Vyvanse accident usually occurs.
- Avoid depressants : Vyvanse collapse symptoms may worsen if you are taking other central nervous system depressants such as alcohol, sedatives, muscle relaxants, anticonvulsants and sleeping pills.
- Sleep hygiene : Lack of sleep also contributes to the collapse of Vyvanse. There are some good habits you can use to ensure you get enough sleep at night, such as doing relaxing activities before bed, going to bed at the same time every night, and eliminating distractions when you go to bed.
- Talk to your doctor : Vyvanse is not necessarily for everyone.
Your healthcare provider may suggest alternatives, such as changing your dose, changing your dosing schedule, or switching to a different medication. - Fatigue
- Excessive sleep
- Depression
- Mood swings
- Increased appetite
- Cravings
- Hypersensitivity to amphetamines or any other Vyvanse ingredient.
- Pregnant or breastfeeding women
- Heart disease, heart defects, arrhythmias or ischemic heart disease.
- Tranylcypromine
- Marplan (isocarboxazid)
- Nardil (radio)phenelzine)
- Linezolid
- Selegiline
- Xadago (safinamide)
- Methylene blue injection
- Caffeine, cocaine or ginseng
- Other drugs for ADHD
- Certain nasal decongestants
- Appetite suppressants such as phendimetrazine
- Awake drugs that treat narcolepsy
- Steroids
- Sympathomimetic drugs such as epinephrine or norepinephrine.
- Alcohol, marijuana or cannabinoids
- Cough medicines
- Drugs
- Sedatives
- Barbiturates
- Axiety
- Preparations for nervous pain
- Anti -road drugs
Antidepressants and serotonergic drugs
Do not use Vyvanse with any other drug that alters serotonin levels unless considered safe by your healthcare provider. Antidepressants, some migraine medications, and certain appetite suppressants taken with Vyvanse increase the risk of serotonin syndrome.
Blood pressure medicines
Amphetamines, such as Vyvanse, increase blood pressure, so they block the action of medicines designed to lower blood pressure.
Combining amphetamines with blood pressure medications will require careful monitoring and possibly modification of therapy. Also avoid the use of amphetamines in combination with drugs that increase blood pressure. Acidifying or alkylating agents
Medicines that increase (acidify) or decrease (alkylate) acid in the stomach or urine, reduce the body's ability to absorb Vyvance and prevent its elimination. In particular, avoid antacids, acidic foods, citrates, and diuretics while taking Vyvanse. Certain multivitamins should also be avoided.
Ask your healthcare professional for a complete list of drug and food interactions.
How to avoid the side effects of Vyvanse
Stimulants like Vyvanse usually cause side effects. Because Vyvanse speeds up the brain, side effects such as decreased appetite, insomnia, high blood pressure, increased heart rate, agitation or restlessness are common. Some patients experience a collapse of Vyvanse similar to a withdrawal syndrome where the drug wears off later in the day.
A few tips to help manage the side effects of Vyvanse:
- Take Vyvanse as directed. Do not increase or decrease the dose. If the medicine does not work or side effects occur, talk to your doctor about changing your dose or switching to a new medicine. Always follow the instructions in the medication guide.
- Take Vyvanse every morning at the same time. Vyvanse should be taken early in the morning. Pick a time at least an hour before alertness and attention is required, and stick to that schedule. If you miss a dose, take it later in the morning. However, do not take your dose in the afternoon to avoid insomnia before bed.
- Report all your medical conditions and medications. This will prevent side effects and dangerous interactions.
- Find an alternative to coffee. Other stimulants may increase the risk and severity of Vyvanse's side effects and avoid them. Apart from some medications, stimulants also include caffeine.
You may need to find an alternative to your daily cup of coffee that will invigorate you. - Practice good sleep hygiene. Sleep problems are one of the most common side effects of Vyvanse. The first step in overcoming medication-induced insomnia is practicing daily sleep hygiene. Avoid TV or video games before bed, develop a nightly relaxation routine, and go to bed at the same time every night.
- Take medication leave (if approved by your doctor). If side effects occur while taking ADHD stimulants, your healthcare provider may advise you to take a dispensation when the medication is stopped or the dose is reduced for several days, weeks, or even months.
However, medication leave is not for everyone. Patients with moderate to severe ADHD symptoms may require a strict dosing schedule. Holidays to take binge eating medication will increase the risk of severe binge eating. Seek professional medical attention first; there may be alternative treatments with fewer side effects.
If you notice symptoms of depression while taking Vivanse, it is important to talk to your doctor. They may suggest treatment options such as prescription drugs, cognitive behavioral therapy, or a combination of therapies. Your doctor may also suggest that you stop taking Vivanse and try another treatment for your condition.
Misuse and risk of addiction
Vivanse has a warning in the box for risk of misuse (also called abuse) and addiction. The boxed warning is the most serious warning from the Food and Drug Administration (FDA). It warns doctors and patients about drug side effects that can be dangerous.
Treatment with Vivanse may lead to physical dependence or misuse. With addiction, your body needs the drug to feel normal. Misuse, on the other hand, means taking the drug differently from what your doctor ordered. This includes taking medications for non-medical purposes.
Misuse can lead to addiction. Some people may also develop addiction when taking Vivance as prescribed. In addiction, it is difficult to stop taking the drug, even if it can cause harm.
Symptoms of misuse of Vivanse may include:
What can help
Your doctor will review your medical history before prescribing Vivanse.
They will look for any risk factors for misuse or addiction. They will also monitor you for any symptoms of abuse or addiction during treatment.
Call your doctor right away if you are concerned about misuse or addiction while taking Vivanse. They may lower your dose or force you to switch to a different drug for your condition.
Because Vivanse can be addictive, it is important that you do not stop taking the drug unless your doctor tells you to. If you need to stop treatment, your doctor will reduce your dose over time. This can help prevent withdrawal symptoms (side effects that can occur when you stop taking a drug your body has become addicted to).
Talk to your doctor or pharmacist if you have any questions about stopping treatment with Vivanse or the risk of abuse or dependence.
Allergic reaction
Like most medicines, Vivanse may cause an allergic reaction in some people. But this side effect was not reported in studies. However, this has been reported since the drug was approved for use.
Symptoms may be mild or severe and may include:
What can help
If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. They may suggest an over-the-counter oral antihistamine such as Benadryl (diphenhydramine) or a topical product such as hydrocortisone cream to relieve your symptoms.
If your doctor confirms that you had a mild allergic reaction to Vivance, they will decide whether you should continue using it.
If you have symptoms of a severe allergic reaction, such as swelling or difficulty breathing, call 911 or your local emergency number immediately. These symptoms can be life threatening and require immediate medical attention.
If your doctor confirms that you have had a serious allergic reaction to Vivance, he may ask you to switch to another treatment.
Tracking side effects
Consider keeping a record of any side effects you experience during your treatment with Vyvanse. You can then share this information with your doctor. This is especially helpful when you first start taking new medications or using a combination of treatments.
Your notes about side effects may include things like:
Taking notes and sharing them with your doctor will help him learn more about how Vivanse is affecting you.
And your doctor can use this information to adjust your treatment plan if necessary.
Warnings for Vivanse
Before deciding to take Vivanse, certain warnings must be taken into account. See below for details.
Warning box: risk of misuse and addiction
Vivanse has a warning in the box for risk of misuse and addiction. The boxed warning is the most serious warning from the Food and Drug Administration (FDA).
The use of stimulant drugs such as Vivanse can lead to abuse and dependence. This can happen even at recommended doses.
See the "Explanation of Side Effects" section above for more information.
Other warnings
Vyvanse may not be right for you if you have certain medical conditions or other health conditions. Talk to your doctor about your medical history before taking Vivanse. The list below includes factors to consider.
Blood flow problems. Vyvanse can cause problems with blood flow in the fingers and toes, including a condition called Raynaud's phenomenon.
If you already have blood flow problems, taking Vivanse may make your condition worse. Your doctor can help determine if it is safe for you to take Vivanse.
Heart problems. In rare cases, Vivanse may cause heart-related side effects, including heart attack, stroke, high blood pressure, or sudden death. You may be at a higher risk of these side effects if you already have heart problems, such as an abnormal heart rhythm or heart disease. Your doctor can help determine if it is safe to take Vivanse for your heart condition.
Kidney problems. Tell your doctor if you have kidney problems such as chronic kidney disease before taking Vivanse. Kidney problems can lead to a buildup of the drug in the body, which can increase the risk of side effects. Your doctor may need to prescribe a lower dose of the drug for you.
Mental health conditions. Vivanse may cause certain psychiatric disorders including mania, depression and psychosis.
If you or a family member has a mental illness, you may be at a higher risk of these side effects if you are taking Vivanse. Your doctor can determine if Vivanse is safe for you. They can also advise you on symptoms to look out for if they prescribe Vivanse for you.
Allergic reaction. If you have had an allergic reaction to Vivanse or any of its ingredients, your doctor will likely not prescribe Vivanse. Ask your doctor which other medicines are best for you.
Alcohol use and Vyvanse
There are no known interactions between alcohol and Vyvanse. But Vivanse has a warning in the box for the risk of abuse and addiction. (See "Explanation of Side Effects" above for more information.)
If you have ever abused or depended on alcohol, your doctor may decide to prescribe a medicine other than Vivanse. This is because you may have a higher risk of misuse or dependence on Vyvanse.
If you drink alcohol, talk to your doctor before taking Vivanse.
They can tell you how much alcohol (if any) is safe for you during treatment.
Pregnancy and lactation while taking Vivanse
There are limited data on the use of Vivanse during pregnancy. But taking Vivanse during pregnancy can harm the fetus.
If you have any questions about using Vivanse during pregnancy, talk to your doctor. If you are taking Vivanse while pregnant, consider registering with the National Pregnancy Registry for ADHD medications. Pregnancy registries collect information about the safety of certain medicines when taken during pregnancy.
You should not breastfeed while taking Vivanse. This is due to the fact that the drug passes into breast milk. The drug can cause serious side effects in a breastfed baby. If you have questions about using Vivanse while breastfeeding, talk to your doctor.
What to ask your doctor
If you are looking for treatment options for attention deficit hyperactivity disorder (ADHD) or an eating disorder, your doctor may suggest Vyvanse.
Like most medicines, taking Vivanse can cause side effects in some people.
Talk to your doctor if you are considering treatment with Vivanse. Some examples of questions you might want to ask include:
If you are taking Vivanse for ADHD, consider subscribing to the Drink-Drink online newsletter. This resource offers guidance on managing your condition and provides answers to frequently asked questions.
Ask a pharmacist
Q:
If I need to stop taking Vivanse, will I have withdrawal symptoms?
Anonymous
A:
If you suddenly stop taking Vivanse, withdrawal symptoms may result. Since your body can become dependent on Vyvanse, it is important that you do not stop taking the drug unless your doctor has recommended it.
(With addiction, your body needs the drug to feel normal.)
Withdrawal symptoms are side effects that occur when you stop taking a drug that your body has become addicted to. Examples of these symptoms include:
If you and your doctor decide to gradually decrease your dose over time, your doctor will decide to stop your treatment over time. This helps prevent withdrawal symptoms.
If you have any questions about stopping your Vivanse treatment, talk to your doctor.
Tanya Kerstman, PharmD Answers represent the opinions of our medical experts. All content is for informational purposes only and should not be considered medical advice.
Registration data: Drink-Drink has made every effort to ensure that all information is accurate, complete and up to date. However, this article should not be used as a substitute for the knowledge and experience of a licensed healthcare professional.
You should always check with your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or side effects. The absence of warnings or other information for a given medicinal product does not mean that the drug or combination of drugs is safe, effective, or suitable for all patients or for all specific uses.
Side effects of Vyvanse and how to avoid them - Product Information
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Information about the drug
Side effects of Vyvanse | Wreck of Vyvanse | Weight loss | Anxiety | Conclusion | How long do side effects last? | Warnings | Interactions | How to avoid side effects
Vyvanse (active ingredient: lisdexamfetamine dimesylate) is a brand-name prescription drug that treats attention deficit hyperactivity disorder (ADHD) in adults and children over 6 years of age.
It is also approved for the treatment of compulsive overeating (BED) in adults, but is usually used as a second line therapy.
Vyvanse belongs to a class of central nervous system stimulants called amphetamines. Its main effect is to speed up the work of the brain. Unlike most other stimulant drugs, Vyvanse is a prodrug, which means that it does not work until it is metabolized into an active form by the body. dextroamphetamine. Like all stimulant medications, Vyvans may not be suitable for everyone. Talk to your doctor about side effects, warnings, and drug interactions before you start taking this medicine.
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Common Side Effects of Vyvanse
Side effects of Vyvanse will vary from patient to patient.
Stimulants reduce hyperactivity, inattention, and impulsivity in ADHD patients, but may have the opposite effect in patients. misdiagnosed ADHD. Someone who takes Vyvanse but does not need it may experience restlessness, restlessness, agitation, nervousness, heart palpitations, or excessive sweating.
In the treatment of ADHD, the most frequent side effects of Vivans are:
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PERSONAL SINGIONALS VyVanse
02 All drugs, which affect the central unarms. life-threatening side effects. Many of the serious side effects of Vyvanse are due to its effect on speeding up the brain and nervous system.
The most serious side effects of VyVanse include:
Vyvanse crash
The effect of the morning dose of Vyvanse or usually disappears in the afternoon. When they do this, some patients experience a Vyvanse accident characterized by fatigue, fatigue, depression, irritability, anxiety, nervousness, and mood swings. The symptoms of Vyvanse collapse are very similar to Vyvanse withdrawal syndrome.
The crash of Vyvanse is not always avoidable, but it can be successfully managed:
Weight loss
Two prominent side effects of Vyvanse are decreased appetite and weight loss. Although decreased appetite is equally common in adults and children, weight loss is a more common side effect of Vyvanse in children. In the initial clinical trials of Vyvanse, nearly one in ten children who took Vyvanse for four weeks lost weight in proportion to the dose: the higher the dose, the greater the average weight loss. Children on Vivance also grow more slowly than other children.
Only 3% of adults who took Vyvans for ADHD lost weight over the same four-week period. However, when Vyvanse is taken for compulsive overeating, weight loss has been observed in 4% of patients. More recent studies show that a clinically significant number of people with binge eating habits lose weight while taking Vivanse by reducing their appetite and the number of binge episodes each week.
Because decreased appetite and weight loss are side effects of Vyvanse, some physicians prescribe Vyvanse off-label. severe obesity in children and adolescents.
Anxiety
In previous studies, 5% to 6% of adults reported anxiety as a side effect of Vyvanse. Children are less likely to experience anxiety as a side effect of Vivanse. In one study, anxiety and agitation were observed in less than 1% of children.
Normally, stimulants like Vyvanse speed up and excite the brain, so alertness, energy, nervousness, restlessness, agitation, jittery thoughts, and restlessness are common side effects. However, in people with ADHD, certain stimulants increase alertness, attention, and impulse control, while reducing hyperactivity, anxiety, and restlessness. These stimulants increase the amount of certain chemicals in the brain - dopamine and norepinephrine. Because ADHD patients do not produce enough of these chemicals, stimulants improve their ability to manage hyperactivity and attention.
Too much dopamine and norepinephrine, a chemical similar to adrenaline, overstimulates the brain and causes increased energy, inattention, nervousness, agitation, excitability, or euphoria. If a person with normal dopamine and norepinephrine levels is experiencing anxiety, Vyvans is likely to exacerbate the anxiety. Side effects such as restlessness, nervousness, and tension may indicate that either Vyvanse or the prescribed dose is inappropriate.
Terminal
Vyvanse is a Schedule II controlled substance, meaning it has a high potential for abuse and dependence. Long-term use of Vyvanse may cause withdrawal symptoms if the dose is reduced or the drug is abruptly discontinued. These symptoms include:
The attending physician may use a gradually decreasing dose to prevent or reduce withdrawal symptoms.
There are certain side effects, such as serotonin syndrome or heart problems, that will require immediate discontinuation of Vyvans.
How long do side effects last?
Vyvans remains active in the body for eight to 14 hours, so the side effects should disappear within this time. However, Vyvanse withdrawal symptoms can last up to seven days. If side effects persist after stopping Vivans, contact your doctor.
Vyvanse contraindications and warnings
Vyvanse is not for everyone. People with the following conditions should not take Vyvanse:
There are other warnings.
People taking monoamine oxidase inhibitors (MAOIs), a class of drugs that includes certain types of antidepressants, antibiotics, or drugs that treat Parkinson's disease, will not be given Vyvans until they have stopped taking MAOIs for at least 14 days.
Slow growth in children
Vyvanse has been approved by the FDA as a safe treatment for ADHD in children aged 6 to 17 years. However, Vyvanse inhibits growth in children, so height and weight must be carefully monitored. If growth suppression is too pronounced, it may be necessary to change Vivanse's therapy.
Pregnancy and lactation
Insufficient data to determine the safety of using Vivanse in pregnant or nursing mothers. Dextroamphetamine crosses the placenta and is present in small amounts in breast milk. However, if you have been taking Vyvanse, do not stop it suddenly without talking to your doctor.
Elderly
The safety of using Vyvanse in people over 65 years of age has not been well studied. If considered safe by a healthcare professional, older people often start with a low dose of Vivanse.
Vyvanse interactions
Vyvanse has clinically significant interactions with more than 200 drugs and other substances. Most of these interactions are not dangerous, but people may notice that Vivans or other drugs are less effective when taken together.
MAO inhibitors
Vyvanse should never be taken for at least 14 days after taking monoamine oxidase inhibitors (MAOIs), including certain types of antidepressants, antibiotics, and Parkinson's drugs such as:
When combined with Vivance, these drugs can cause dangerously high blood pressure.
Stimulants
Vyvans may increase the effects of other CNS stimulants, including increased blood pressure and heart rate. CNS stimulants include:
Depressants
In general, the combination of stimulants with depressants is rarely recommended. Amphetamines such as Vyvanse usually reduce the effects of depressants, but some combinations of amphetamines and depressants can be dangerous. Vyvanse should not be used with depressants such as:
